| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Áurea Gabriela Rodrigues Mendes, Gabriel Gomes Vilar de Sousa, Martha de Souza França, Carlos Alberto Marques de Carvalho, Evander de Jesus Oliveira Batista, Adelaide da Conceição Fonseca Passos, Karen Renata Herculano Matos Oliveira, Anderson Manoel Herculano, Suellen Alessandra Soares de Morae. Astrocyte reactivity in spinal cord and functional impairment after tendon injury in rats. Heliyon. vol 7. issue 4. 2021-05-14. PMID:33981899. |
we conclude that during the acute phase of achilles tendon repairment, there was astrocyte reactivity in the spinal cord and impairment of mechanical sensitivity and gait, whereas in the chronic phase only gait remains compromised. |
2021-05-14 |
2023-08-13 |
rat |
| Lu-Xia Ye, Ning-Chen An, Peng Huang, Duo-Hui Li, Zhi-Long Zheng, Hao Ji, Hao Li, Da-Qing Chen, Yan-Qing Wu, Jian Xiao, Ke Xu, Xiao-Kun Li, Hong-Yu Zhan. Exogenous platelet-derived growth factor improves neurovascular unit recovery after spinal cord injury. Neural regeneration research. vol 16. issue 4. 2021-04-29. PMID:33063740. |
our results showed that after platelet-derived growth factor administration, spinal cord injury, neuronal apoptosis, and blood-spinal cord barrier permeability were reduced, excessive astrocyte proliferation and the autophagy-related apoptosis signaling pathway were inhibited, collagen synthesis was increased, and mouse locomotor function was improved. |
2021-04-29 |
2023-08-13 |
mouse |
| Monokesh K Sen, Mohammed S M Almuslehi, Jens R Coorssen, David A Mahns, Peter J Shortlan. Behavioural and histological changes in cuprizone-fed mice. Brain, behavior, and immunity. vol 87. 2021-04-27. PMID:32014578. |
no loss of oligodendrocytes, neurons or motoneurons occurred but a significant increase in astrocyte staining ensued throughout the white matter of the spinal cord. |
2021-04-27 |
2023-08-13 |
mouse |
| Abdulaziz M F Shayea, Alyaa M A Mousa, Waleed M Renno, Mohammed Shaban Nadar, Bedoor Qabazard, Mariam H M Yousi. Chronic Treatment With Hydrogen Sulfide Donor GYY4137 Mitigates Microglial and Astrocyte Activation in the Spinal Cord of Streptozotocin-Induced Diabetic Rats. Journal of neuropathology and experimental neurology. vol 79. issue 12. 2021-03-05. PMID:33271602. |
chronic treatment with hydrogen sulfide donor gyy4137 mitigates microglial and astrocyte activation in the spinal cord of streptozotocin-induced diabetic rats. |
2021-03-05 |
2023-08-13 |
rat |
| Abdulaziz M F Shayea, Alyaa M A Mousa, Waleed M Renno, Mohammed Shaban Nadar, Bedoor Qabazard, Mariam H M Yousi. Chronic Treatment With Hydrogen Sulfide Donor GYY4137 Mitigates Microglial and Astrocyte Activation in the Spinal Cord of Streptozotocin-Induced Diabetic Rats. Journal of neuropathology and experimental neurology. vol 79. issue 12. 2021-03-05. PMID:33271602. |
the treatment decreased the microglial response and increased astrocyte counts in spinal cord gray and white matter compared with untreated diabetic rats. |
2021-03-05 |
2023-08-13 |
rat |
| Pol Andrés-Benito, Mònica Povedano, Raúl Domínguez, Carla Marco, Maria J Colomina, Óscar López-Pérez, Isabel Santana, Inês Baldeiras, Sergio Martínez-Yelámos, Inga Zerr, Franc Llorens, Joaquín Fernández-Irigoyen, Enrique Santamaría, Isidro Ferre. Increased C-X-C Motif Chemokine Ligand 12 Levels in Cerebrospinal Fluid as a Candidate Biomarker in Sporadic Amyotrophic Lateral Sclerosis. International journal of molecular sciences. vol 21. issue 22. 2021-03-03. PMID:33213069. |
cxcl12/cxcr4/cxcr7 axis in the spinal cord probably plays a complex role in inflammation, oligodendroglial and astrocyte signaling, and neuronal and axonal preservation in sals. |
2021-03-03 |
2023-08-13 |
Not clear |
| Sebok K Halder, Richard Milne. The GFAP Monoclonal Antibody GA-5 Identifies Astrocyte Remodeling and Glio-Vascular Uncoupling During the Evolution of EAE. Cellular and molecular neurobiology. 2021-02-05. PMID:33544272. |
to examine how astrocyte activation is regulated at different phases of relapsing-remitting eae, we performed an immunofluorescent analysis of the spinal cord using the anti-glial fibrillary acidic protein (gfap) monoclonal antibody ga-5. |
2021-02-05 |
2023-08-13 |
Not clear |
| Ju-Young Oh, Tae-Yeon Hwang, Jae-Hwan Jang, Ji-Yeun Park, Yeonhee Ryu, HyeJung Lee, Hi-Joon Par. Muscovite nanoparticles mitigate neuropathic pain by modulating the inflammatory response and neuroglial activation in the spinal cord. Neural regeneration research. vol 15. issue 11. 2020-12-11. PMID:32394976. |
in the spinal cord, the muscovite nanoparticle injections exhibited inhibitory effects on astrocyte and microglia activation and reduced the expression of pro-inflammatory cytokines, such as interleukin-1β, tumor necrosis factor-α, interleiukin-6 and monocyte chemoattractant protein-1, which were upregulated in the partial sciatic nerve ligation model. |
2020-12-11 |
2023-08-13 |
Not clear |
| Gang Li, Yang Cao, Feifei Shen, Yangsong Wang, Liangjie Bai, Weidong Guo, Yunlong Bi, Gang Lv, Zhongkai Fa. Mdivi-1 Inhibits Astrocyte Activation and Astroglial Scar Formation and Enhances Axonal Regeneration after Spinal Cord Injury in Rats. Frontiers in cellular neuroscience. vol 10. 2020-10-01. PMID:27807407. |
mdivi-1 inhibits astrocyte activation and astroglial scar formation and enhances axonal regeneration after spinal cord injury in rats. |
2020-10-01 |
2023-08-13 |
rat |
| An-Chen Guo, Takho Chu, Xu-Qing Liu, Huan-Xing Su, Wu-Tian W. Reactivated astrocytes as a possible source of oligodendrocyte precursors for remyelination in remitting phase of experimental autoimmune encephalomyelitis rats. American journal of translational research. vol 8. issue 12. 2020-10-01. PMID:28078034. |
we suggest that activated astrocyte could de-differentiate into opcs and re-differentiate into mature oligodendrocytes, raising the possibility that astrocytes can be a potential source of opcs in the adult demyelinated spinal cord. |
2020-10-01 |
2023-08-13 |
rat |
| Marcus Berndt, Yongchao Li, Negar Seyedhassantehrani, Li Ya. Fabrication and characterization of microspheres encapsulating astrocytes for neural regeneration. ACS biomaterials science & engineering. vol 3. issue 7. 2020-10-01. PMID:28948211. |
recent studies have revealed that astrocyte transplantation can promote axonal regeneration and functional recovery after spinal cord injury. |
2020-10-01 |
2023-08-13 |
rat |
| Marcus Berndt, Yongchao Li, Negar Seyedhassantehrani, Li Ya. Fabrication and characterization of microspheres encapsulating astrocytes for neural regeneration. ACS biomaterials science & engineering. vol 3. issue 7. 2020-10-01. PMID:28948211. |
biomaterial can be designed as a growth-permissive substrate and serve as a carrier for astrocyte transplantation into injured spinal cord. |
2020-10-01 |
2023-08-13 |
rat |
| Atsushi Takazawa, Naosuke Kamei, Nobuo Adachi, Mitsuo Och. Endoplasmic reticulum stress transducer old astrocyte specifically induced substance contributes to astrogliosis after spinal cord injury. Neural regeneration research. vol 13. issue 3. 2020-09-29. PMID:29623941. |
endoplasmic reticulum stress transducer old astrocyte specifically induced substance contributes to astrogliosis after spinal cord injury. |
2020-09-29 |
2023-08-13 |
mouse |
| Qian Zhang, Li-Xin Zhang, Jing An, Liang Yan, Cui-Cui Liu, Jing-Jing Zhao, Hao Yan. Neural regeneration research. vol 13. issue 12. 2020-09-29. PMID:30323153. |
immunofluorescence and western blot assays were performed to measure immunoreactivity and expression levels of brain-derived neurotrophic factor, neuronal marker neurofilament protein, microglial marker cd11b and astrocyte marker glial fibrillary acidic protein in the injured spinal cord. |
2020-09-29 |
2023-08-13 |
rat |
| Ryan T Muir, Aditya Bharatha, Dalia Rotstei. Mirror-Image Lesions in Sequential Relapses of AQP4-Positive Neuromyelitis Optica Spectrum Disorder. Frontiers in neurology. vol 11. 2020-09-28. PMID:32477258. |
we hypothesize, using data from prior pathologic and epidemiologic studies, that mirror image lesions, where the same anatomic sites are affected on the contralateral side of the brain or spinal cord, may appear in subsequent attacks due to (i) areas of high remaining aqp4 density and/or (ii) local compromise of astrocyte or blood-brain barrier (bbb) function that persists after the initial inciting attack. |
2020-09-28 |
2023-08-13 |
Not clear |
| Kazuki Ohuchi, Michinori Funato, Yuta Yoshino, Shiori Ando, Satoshi Inagaki, Arisu Sato, Chizuru Kawase, Junko Seki, Toshio Saito, Hisahide Nishio, Shinsuke Nakamura, Masamitsu Shimazawa, Hideo Kaneko, Hideaki Har. Notch Signaling Mediates Astrocyte Abnormality in Spinal Muscular Atrophy Model Systems. Scientific reports. vol 9. issue 1. 2020-09-24. PMID:30842449. |
in the present study, we found that the astrocyte density was increased around the central canal of the spinal cord in a mouse sma model and we identified the dysregulation of notch signaling which is a known mechanism that regulates astrocyte differentiation and proliferation, in the spinal cord in both early and late stages of sma pathogenesis. |
2020-09-24 |
2023-08-13 |
mouse |
| Hui Kan Hong, Yi Ma, Hengtao Xi. TRPV1 and spinal astrocyte activation contribute to remifentanil-induced hyperalgesia in rats. Neuroreport. vol 30. issue 16. 2020-07-14. PMID:31568203. |
immunofluorescence assay was applied to analyze the activation of astrocyte in spinal cord. |
2020-07-14 |
2023-08-13 |
rat |
| Hui Kan Hong, Yi Ma, Hengtao Xi. TRPV1 and spinal astrocyte activation contribute to remifentanil-induced hyperalgesia in rats. Neuroreport. vol 30. issue 16. 2020-07-14. PMID:31568203. |
moreover, remifentanil also increased the tnf-α, il-1β, and il-6 levels and activates the astrocyte in spinal cord. |
2020-07-14 |
2023-08-13 |
rat |
| Ignacio Jure, Alejandro F De Nicola, Florencia Labombard. Progesterone effects on oligodendrocyte differentiation in injured spinal cord. Brain research. vol 1708. 2020-06-15. PMID:30527678. |
notwithstanding that astrocyte, oligodendrocyte precursor and microglial cell density increased after spinal cord injury, the number of these cells which expressed tgfβ1 remained unchanged regarding sham operated rats. |
2020-06-15 |
2023-08-13 |
rat |
| Lun Li, Li Ni, Eliseo A Eugenin, Robert F Heary, Stella Elkabe. Toll-like receptor 9 antagonism modulates astrocyte function and preserves proximal axons following spinal cord injury. Brain, behavior, and immunity. vol 80. 2020-05-21. PMID:30953770. |
toll-like receptor 9 antagonism modulates astrocyte function and preserves proximal axons following spinal cord injury. |
2020-05-21 |
2023-08-13 |
mouse |