| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Teresa Fernandez-Zafra, Tianle Gao, Alexandra Jurczak, Katalin Sandor, Zoe Hore, Nilesh M Agalave, Jie Su, Johanna Estelius, Jon Lampa, Tomas Hokfelt, Zsuzsanna Wiesenfeld-Hallin, Xiaojun Xu, Franziska Denk, Camilla I Svensso. Exploring the transcriptome of resident spinal microglia after collagen antibody-induced arthritis. Pain. vol 160. issue 1. 2019-06-26. PMID:30247264. |
although the intensity of substance p, calcitonin gene-related peptide, and galanin immunoreactivity in the spinal cord was not different from controls, the intensity of microglia (iba-1) and astrocyte (glial fibrillary acidic protein) markers was elevated in both males and females. |
2019-06-26 |
2023-08-13 |
mouse |
| Miguel Goulão, Biswarup Ghosh, Mark W Urban, Malya Sahu, Christina Mercogliano, Brittany A Charsar, Sreeya Komaravolu, Cole G Block, George M Smith, Megan C Wright, Angelo C Lepor. Astrocyte progenitor transplantation promotes regeneration of bulbospinal respiratory axons, recovery of diaphragm function, and a reduced macrophage response following cervical spinal cord injury. Glia. vol 67. issue 3. 2019-06-13. PMID:30548313. |
astrocyte progenitor transplantation promotes regeneration of bulbospinal respiratory axons, recovery of diaphragm function, and a reduced macrophage response following cervical spinal cord injury. |
2019-06-13 |
2023-08-13 |
Not clear |
| Mingxiao Zhang, Qinxue Dai, Dongdong Liang, Dan Li, Sijia Chen, Shuangdong Chen, Kunyuan Han, Luping Huang, Junlu Wan. Involvement of adenosine A1 receptor in electroacupuncture-mediated inhibition of astrocyte activation during neuropathic pain. Arquivos de neuro-psiquiatria. vol 76. issue 11. 2019-06-10. PMID:30570016. |
electroacupuncture (ea) has an antinociceptive effect on neuropathic pain, which is partially due to inhibiting astrocyte activation in the spinal cord. |
2019-06-10 |
2023-08-13 |
Not clear |
| Pooja Singhmar, XiaoJiao Huo, Yan Li, Patrick M Dougherty, Fang Mei, Xiaodong Cheng, Cobi J Heijnen, Annemieke Kavelaar. Orally active Epac inhibitor reverses mechanical allodynia and loss of intraepidermal nerve fibers in a mouse model of chemotherapy-induced peripheral neuropathy. Pain. vol 159. issue 5. 2019-06-04. PMID:29369966. |
in addition, spinal cord astrocyte activation and intraepidermal nerve fiber (ienf) loss are significantly reduced in epac1-/- mice as compared to wild-type mice. |
2019-06-04 |
2023-08-13 |
mouse |
| Pooja Singhmar, XiaoJiao Huo, Yan Li, Patrick M Dougherty, Fang Mei, Xiaodong Cheng, Cobi J Heijnen, Annemieke Kavelaar. Orally active Epac inhibitor reverses mechanical allodynia and loss of intraepidermal nerve fibers in a mouse model of chemotherapy-induced peripheral neuropathy. Pain. vol 159. issue 5. 2019-06-04. PMID:29369966. |
in addition, oral administration of esi-09 suppressed spinal cord astrocyte activation in the spinal cord and protected against ienf loss. |
2019-06-04 |
2023-08-13 |
mouse |
| Wenqian Yang, Qulian Guo, Zhigang Cheng, Yunjiao Wang, Nianyue Bai, Zhenghua H. [mTOR signaling pathway of spinal cord is involved in peripheral nerve injury-induced hyperalgesia in rats]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 44. issue 4. 2019-05-30. PMID:31113912. |
the gfap immunohistochemistry positive area and absorbance value in the dorsal horn of the lumbar spinal cord in the cci rats were decreased in the cci+early rapa group compared with the cci+early dmso group (p<0.05 or p<0.01), and which were also decreased in the cci+later rapa group compared with the cci+later dmso group (p<0.05 or p<0.01).
conclusion: mtor signaling pathway may be involved in hyperalgesia induced by peripheral nerve injury via spinal astrocyte activation in the dorsal horn of the spinal cord. |
2019-05-30 |
2023-08-13 |
rat |
| Keisuke Miyamoto, Kei-Ichiro Ishikura, Kazuhiko Kume, Masahiro Ohsaw. Astrocyte-neuron lactate shuttle sensitizes nociceptive transmission in the spinal cord. Glia. vol 67. issue 1. 2019-05-15. PMID:30430652. |
astrocyte activation in the spinal cord is involved in the expression of neuropathic pain. |
2019-05-15 |
2023-08-13 |
mouse |
| M Bobinac, T Ćelić, I Vukelić, J Španjol, N Rubinić, D Bobina. Nuclear factor erythroid 2-related factor 2 and choline acetyltransferase co-expression in rat spinal cord neurons after ischemia-reperfusion injury. Journal of biological regulators and homeostatic agents. vol 32. issue 4. 2019-05-06. PMID:30043562. |
the animals used for this study were sacrificed 1 h, 6 h, and 48 h after reperfusion to determine time-related changes of nrf2 expression, as well as changes of astrocyte activity in the spinal cord. |
2019-05-06 |
2023-08-13 |
rat |
| Fabrício Nicola, Marília Rossato Marques, Felipe Odorcyk, Letícia Petenuzzo, Dirceu Aristimunha, Adriana Vizuete, Eduardo Farias Sanches, Daniela Pavulack Pereira, Natasha Maurmann, Carlos-Alberto Gonçalves, Patricia Pranke, Carlos Alexandre Nett. Stem Cells from Human Exfoliated Deciduous Teeth Modulate Early Astrocyte Response after Spinal Cord Contusion. Molecular neurobiology. vol 56. issue 1. 2019-04-01. PMID:29796991. |
stem cells from human exfoliated deciduous teeth modulate early astrocyte response after spinal cord contusion. |
2019-04-01 |
2023-08-13 |
human |
| Lang-Yue Hu, Yang Zhou, Wen-Qiang Cui, Xue-Ming Hu, Li-Xia Du, Wen-Li Mi, Yu-Xia Chu, Gen-Cheng Wu, Yan-Qing Wang, Qi-Liang Mao-Yin. Triggering receptor expressed on myeloid cells 2 (TREM2) dependent microglial activation promotes cisplatin-induced peripheral neuropathy in mice. Brain, behavior, and immunity. vol 68. 2019-03-12. PMID:29051087. |
in the spinal cord, activation of microglia, but not astrocyte, was persistently observed until week five after the first cisplatin injection. |
2019-03-12 |
2023-08-13 |
mouse |
| Jiannan Zhang, Bingxu Ren, Kun Ni, Yue Liu, Zhengliang M. [Intrathecal injection of AG-490 reduces bone-cancer-induced spinal cord astrocyte reaction and thermal hyperalgesia in a mouse model]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 43. issue 11. 2019-02-13. PMID:30643061. |
[intrathecal injection of ag-490 reduces bone-cancer-induced spinal cord astrocyte reaction and thermal hyperalgesia in a mouse model]. |
2019-02-13 |
2023-08-13 |
mouse |
| Yoshikazu Sumida, Naosuke Kamei, Norifumi Suga, Mitsuo Ochi, Nobuo Adach. The endoplasmic reticulum stress transducer old astrocyte specifically induced substance positively regulates glial scar formation in spinal cord injury. Neuroreport. vol 29. issue 17. 2019-02-12. PMID:30273224. |
the endoplasmic reticulum stress transducer old astrocyte specifically induced substance positively regulates glial scar formation in spinal cord injury. |
2019-02-12 |
2023-08-13 |
mouse |
| Yoshikazu Sumida, Naosuke Kamei, Norifumi Suga, Mitsuo Ochi, Nobuo Adach. The endoplasmic reticulum stress transducer old astrocyte specifically induced substance positively regulates glial scar formation in spinal cord injury. Neuroreport. vol 29. issue 17. 2019-02-12. PMID:30273224. |
to investigate the relationship between endoplasmic reticulum (er) stress mediated by old astrocyte specifically induced substance (oasis) and astrogliosis in spinal cord injury (sci). |
2019-02-12 |
2023-08-13 |
mouse |
| Yanfei Shao, Biqin Tan, Jing Shi, Qian Zho. Methotrexate induces astrocyte apoptosis by disrupting folate metabolism in the mouse juvenile central nervous system. Toxicology letters. vol 301. 2019-01-07. PMID:30502384. |
moreover, gfap-labeled astrocyte cells significantly decreased in the mouse spinal cord and brain. |
2019-01-07 |
2023-08-13 |
mouse |
| Cheng-Ta Hsieh, Yih-Jing Lee, Xiaoli Dai, Norma Beatriz Ojeda, Hyun Joon Lee, Lu-Tai Tien, Lir-Wan Fa. Systemic Lipopolysaccharide-Induced Pain Sensitivity and Spinal Inflammation Were Reduced by Minocycline in Neonatal Rats. International journal of molecular sciences. vol 19. issue 10. 2018-12-11. PMID:30262747. |
the levels of microglia and astrocyte activation, pro-inflammatory cytokine interleukin-1β (il-1β), cyclooxygenase-2 (cox-2), and prostaglandin e2 (pge2) in the spinal cord of neonatal rats were increased 24 h after the administration of lps. |
2018-12-11 |
2023-08-13 |
rat |
| Cheng-Ta Hsieh, Yih-Jing Lee, Xiaoli Dai, Norma Beatriz Ojeda, Hyun Joon Lee, Lu-Tai Tien, Lir-Wan Fa. Systemic Lipopolysaccharide-Induced Pain Sensitivity and Spinal Inflammation Were Reduced by Minocycline in Neonatal Rats. International journal of molecular sciences. vol 19. issue 10. 2018-12-11. PMID:30262747. |
treatment with minocycline significantly attenuated lps-induced allodynia, hyperalgesia, the increase in spinal cord microglia, and astrocyte activation, and elevated levels of il-1β, cox-2, and pge2 in neonatal rats. |
2018-12-11 |
2023-08-13 |
rat |
| Xiongsong Lu, Pengfei Xue, Luyu Fu, Jinlong Zhang, Jiawei Jiang, Xiaofeng Guo, Guofeng Bao, Guanhua Xu, Yuyu Sun, Jiajia Chen, Zhiming Cu. HAX1 is associated with neuronal apoptosis and astrocyte proliferation after spinal cord injury. Tissue & cell. vol 54. 2018-12-11. PMID:30309497. |
hax1 is associated with neuronal apoptosis and astrocyte proliferation after spinal cord injury. |
2018-12-11 |
2023-08-13 |
rat |
| Ya-Lan Zhou, Shu-Zhuan Zhou, Hao-Ling Li, Man-Li Hu, Hui Li, Qing-Huan Guo, Xiao-Ming Deng, Yu-Qiu Zhang, Hua X. Bidirectional modulation between infiltrating CD3 Scientific reports. vol 8. issue 1. 2018-11-21. PMID:29311654. |
the establishment of monoarthritis produced t cell infiltration and astrocyte activation, exhibiting similar kinetics in the spinal cord. |
2018-11-21 |
2023-08-13 |
Not clear |
| Lihui Zhou, Lian Ouyang, Shuangzhi Lin, Song Chen, YingJie Liu, Wei Zhou, Xucan Wan. Protective role of β-carotene against oxidative stress and neuroinflammation in a rat model of spinal cord injury. International immunopharmacology. vol 61. 2018-11-05. PMID:29857242. |
additionally, β-carotene decreased the generation of pro-inflammatory cytokines, including tumor necrosis factor-α, interleukin-1β, interleukin-18 and cyclooxygenase-2, and inhibited the activation of astrocyte in the spinal cord. |
2018-11-05 |
2023-08-13 |
rat |
| Yeyang Wang, Wenjun Li, Mingsen Wang, Chuangxin Lin, Guitao Li, Xiaozhong Zhou, Junnan Luo, Dadi Ji. Quercetin reduces neural tissue damage and promotes astrocyte activation after spinal cord injury in rats. Journal of cellular biochemistry. vol 119. issue 2. 2018-10-15. PMID:28865131. |
quercetin reduces neural tissue damage and promotes astrocyte activation after spinal cord injury in rats. |
2018-10-15 |
2023-08-13 |
rat |