| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| David Ohayon, Alain Garcès, Willy Joly, Chadi Soukkarieh, Tsuyoshi Takagi, Jean-Charles Sabourin, Eric Agius, Douglas S Darling, Pascal De Santa Barbara, Yujiro Higashi, Claus C Stolt, Jean-Philippe Hugnot, William D Richardson, Patrick Carroll, Alexandre Patty. Onset of Spinal Cord Astrocyte Precursor Emigration from the Ventricular Zone Involves the Zeb1 Transcription Factor. Cell reports. vol 17. issue 6. 2017-11-20. PMID:27806288. |
during spinal cord development, astrocyte precursors arise from neuroepithelial progenitors, delaminate from the ventricular zone, and migrate toward their final locations where they differentiate. |
2017-11-20 |
2023-08-13 |
Not clear |
| Wei Jiang, Ying Wang, Wei Sun, Mengyuan Zhan. Morin Suppresses Astrocyte Activation and Regulates Cytokine Release in Bone Cancer Pain Rat Models. Phytotherapy research : PTR. vol 31. issue 9. 2017-09-25. PMID:28618070. |
morin (5-20 mg/kg) dose-dependently attenuated behavioral hypersensitivities, including mechanical allodynia and free movement pain, which was accompanied by downregulation of astrocyte marker glial fibrillary acidic protein in the spinal cord in cancer-bearing rats. |
2017-09-25 |
2023-08-13 |
human |
| Hyesook Yoon, Grant Walters, Alex R Paulsen, Isobel A Scarisbric. Astrocyte heterogeneity across the brain and spinal cord occurs developmentally, in adulthood and in response to demyelination. PloS one. vol 12. issue 7. 2017-09-25. PMID:28700615. |
astrocyte heterogeneity across the brain and spinal cord occurs developmentally, in adulthood and in response to demyelination. |
2017-09-25 |
2023-08-13 |
Not clear |
| Hyesook Yoon, Grant Walters, Alex R Paulsen, Isobel A Scarisbric. Astrocyte heterogeneity across the brain and spinal cord occurs developmentally, in adulthood and in response to demyelination. PloS one. vol 12. issue 7. 2017-09-25. PMID:28700615. |
equivalent elevations in gfap, gfap/aldh1l1 ratios, and in il-6, were observed in primary astrocyte cultures derived from spinal cord compared to cortex. |
2017-09-25 |
2023-08-13 |
Not clear |
| Hyesook Yoon, Grant Walters, Alex R Paulsen, Isobel A Scarisbric. Astrocyte heterogeneity across the brain and spinal cord occurs developmentally, in adulthood and in response to demyelination. PloS one. vol 12. issue 7. 2017-09-25. PMID:28700615. |
altogether, these studies point to key differences in astrocyte abundance and the expression of gfap and il-6 across the brain and spinal cord that are positioned to influence regional specialization developmentally and responses occurring in the context of injury and disease. |
2017-09-25 |
2023-08-13 |
Not clear |
| Michal K Oklinski, Jung-Suk Lim, Hyo-Jung Choi, Paulina Oklinska, Mariusz T Skowronski, Tae-Hwan Kwo. Immunolocalization of Water Channel Proteins AQP1 and AQP4 in Rat Spinal Cord. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 62. issue 8. 2017-09-07. PMID:24828513. |
in contrast, aqp1 did not colocalize with gfap, an astrocyte marker, at any level of the spinal cord. |
2017-09-07 |
2023-08-13 |
rat |
| Lesley S Chaboub, Jeanne M Manalo, Hyun Kyoung Lee, Stacey M Glasgow, Fengju Chen, Yoshihiro Kawasaki, Tetsu Akiyama, Chay T Kuo, Chad J Creighton, Carrie A Mohila, Benjamin Denee. Temporal Profiling of Astrocyte Precursors Reveals Parallel Roles for Asef during Development and after Injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 47. 2017-08-18. PMID:27881777. |
to identify these stages, we performed gene-expression profiling on astrocyte precursor populations in the spinal cord, identifying distinct patterns of gene induction during their development that are strongly correlated with human astrocytes. |
2017-08-18 |
2023-08-13 |
mouse |
| Jessica J Matyas, Cliona M O'Driscoll, Laina Yu, Marina Coll-Miro, Sean Daugherty, Cynthia L Renn, Alan I Faden, Susan G Dorsey, Junfang W. Truncated TrkB.T1-Mediated Astrocyte Dysfunction Contributes to Impaired Motor Function and Neuropathic Pain after Spinal Cord Injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 14. 2017-07-27. PMID:28270575. |
truncated trkb.t1-mediated astrocyte dysfunction contributes to impaired motor function and neuropathic pain after spinal cord injury. |
2017-07-27 |
2023-08-13 |
Not clear |
| Sheu-Ran Choi, Dae-Hyun Roh, Seo-Yeon Yoon, Soon-Gu Kwon, Hoon-Seong Choi, Ho-Jae Han, Alvin J Beitz, Jang-Hern Le. Astrocyte sigma-1 receptors modulate connexin 43 expression leading to the induction of below-level mechanical allodynia in spinal cord injured mice. Neuropharmacology. vol 111. 2017-07-11. PMID:27567941. |
astrocyte sigma-1 receptors modulate connexin 43 expression leading to the induction of below-level mechanical allodynia in spinal cord injured mice. |
2017-07-11 |
2023-08-13 |
mouse |
| Sheu-Ran Choi, Dae-Hyun Roh, Seo-Yeon Yoon, Soon-Gu Kwon, Hoon-Seong Choi, Ho-Jae Han, Alvin J Beitz, Jang-Hern Le. Astrocyte sigma-1 receptors modulate connexin 43 expression leading to the induction of below-level mechanical allodynia in spinal cord injured mice. Neuropharmacology. vol 111. 2017-07-11. PMID:27567941. |
we have previously shown using a spinal cord injury (sci) model that gap junctions contribute to the early spread of astrocyte activation in the lumbar spinal cord and that this astrocyte communication plays critical role in the induction of central neuropathic pain. |
2017-07-11 |
2023-08-13 |
mouse |
| Sheu-Ran Choi, Dae-Hyun Roh, Seo-Yeon Yoon, Soon-Gu Kwon, Hoon-Seong Choi, Ho-Jae Han, Alvin J Beitz, Jang-Hern Le. Astrocyte sigma-1 receptors modulate connexin 43 expression leading to the induction of below-level mechanical allodynia in spinal cord injured mice. Neuropharmacology. vol 111. 2017-07-11. PMID:27567941. |
a thoracic spinal cord hemisection significantly increased both astrocyte activation and cx43 expression in lumbar dorsal horn. |
2017-07-11 |
2023-08-13 |
mouse |
| Svitlana Garbuzova-Davis, Edward Haller, Naoki Tajiri, Avery Thomson, Jennifer Barretta, Stephanie N Williams, Eithan D Haim, Hua Qin, Aric Frisina-Deyo, Jerry V Abraham, Paul R Sanberg, Harry Van Loveren, Cesario V Borlonga. Blood-Spinal Cord Barrier Alterations in Subacute and Chronic Stages of a Rat Model of Focal Cerebral Ischemia. Journal of neuropathology and experimental neurology. vol 75. issue 7. 2017-06-22. PMID:27283328. |
major bscb ultrastructural changes in spinal cord gray and white matter included vacuolated endothelial cells containing autophagosomes, pericyte degeneration with enlarged mitochondria, astrocyte end-feet degeneration and perivascular edema; damaged motor neurons, swollen axons with unraveled myelin in ascending and descending tracts and astrogliosis were also observed. |
2017-06-22 |
2023-08-13 |
rat |
| Alessandra Pacini, Laura Micheli, Mario Maresca, Jacopo Juno Valerio Branca, J Michael McIntosh, Carla Ghelardini, Lorenzo Di Cesare Mannell. The α9α10 nicotinic receptor antagonist α-conotoxin RgIA prevents neuropathic pain induced by oxaliplatin treatment. Experimental neurology. vol 282. 2017-05-09. PMID:27132993. |
in the spinal cord the numerical increase of astrocyte cell density present in oxaliplatin-treated rats is partially prevented by rgia treatment. |
2017-05-09 |
2023-08-13 |
rat |
| Frédéric Sorgeloos, Cécile Lardinois, Sophie Jacobs, Frank J M van Kuppeveld, Bernd Kaspers, Thomas Michiel. Neurotropism of Saffold virus in a mouse model. The Journal of general virology. vol 97. issue 6. 2017-04-28. PMID:26959376. |
the virus was detected by immunohistochemistry in many parts of the brain and spinal cord, both in neurons and astrocytes, but astrocyte infection was more extensive. |
2017-04-28 |
2023-08-13 |
mouse |
| Melanie M Das, Pablo Avalos, Patrick Suezaki, Marlesa Godoy, Leslie Garcia, Christine D Chang, Jean-Philippe Vit, Brandon Shelley, Genevieve Gowing, Clive N Svendse. Human neural progenitors differentiate into astrocytes and protect motor neurons in aging rats. Experimental neurology. vol 280. 2017-04-28. PMID:27032721. |
here, we test whether rejuvenating the astrocyte niche can improve the survival of motor neurons in an aging spinal cord. |
2017-04-28 |
2023-08-13 |
human |
| Melanie M Das, Pablo Avalos, Patrick Suezaki, Marlesa Godoy, Leslie Garcia, Christine D Chang, Jean-Philippe Vit, Brandon Shelley, Genevieve Gowing, Clive N Svendse. Human neural progenitors differentiate into astrocytes and protect motor neurons in aging rats. Experimental neurology. vol 280. 2017-04-28. PMID:27032721. |
we transplanted fetal-derived human neural progenitor cells (hnpcs) into the aging rat spinal cord and found that the cells survive and differentiate into astrocytes with a much higher efficiency than when transplanted into younger animals, suggesting that the aging environment stimulates astrocyte maturation. |
2017-04-28 |
2023-08-13 |
human |
| Tetsuya Ohnou, Masafumi Yokai, Takashi Kurihara, Maiko Hasegawa-Moriyama, Takao Shimizu, Kazuhiko Inoue, Yuki Kambe, Yuichi Kanmura, Atsuro Miyat. Pituitary adenylate cyclase-activating polypeptide type 1 receptor signaling evokes long-lasting nociceptive behaviors through the activation of spinal astrocytes in mice. Journal of pharmacological sciences. vol 130. issue 4. 2017-04-20. PMID:26948958. |
immunohistochemistry and immunoblotting analysis revealed that spinal administration of max-induced erk phosphorylation and jnk phosphorylation, and also augmented an astrocyte marker, glial fibrillary acidic protein in mouse spinal cord. |
2017-04-20 |
2023-08-13 |
mouse |
| Xingxing Mao, Jin Liu, Chen Chen, Weidong Zhang, Rong Qian, Xinlei Chen, Hongjian Lu, Jianbing Ge, Chengjin Zhao, Dongmei Zhang, Youhua Wan. PCBP2 Modulates Neural Apoptosis and Astrocyte Proliferation After Spinal Cord Injury. Neurochemical research. vol 41. issue 9. 2017-04-17. PMID:27209304. |
pcbp2 modulates neural apoptosis and astrocyte proliferation after spinal cord injury. |
2017-04-17 |
2023-08-13 |
human |
| Caixia Sun, Jin Zhang, Li Chen, Tanghua Liu, Gaobing Xu, Chunye Li, Wen Yuan, Huaxi Xu, Zhaoliang S. IL-17 contributed to the neuropathic pain following peripheral nerve injury by promoting astrocyte proliferation and secretion of proinflammatory cytokines. Molecular medicine reports. vol 15. issue 1. 2017-03-31. PMID:27959414. |
the present study, based on the rat model of spinal nerve ligation, analyzed the infiltration of cluster of differentiation (cd)4+ t cells and the expression of il‑17 in the spinal cord during the maintenance phase of neuropathic pain, and investigated central inflammatory reaction and astrocyte activation. |
2017-03-31 |
2023-08-13 |
rat |
| Zhijuan Cao, Wenling Dai, Ran Zhang, Lu Chen, Xiangyu Yang, Liang Hu, Li-Yang Chiang, Wentao Li. Opening of the Adenosine Triphosphate-sensitive Potassium Channel Attenuates Morphine Tolerance by Inhibiting JNK and Astrocyte Activation in the Spinal Cord. The Clinical journal of pain. vol 32. issue 7. 2017-03-24. PMID:26626290. |
opening of the adenosine triphosphate-sensitive potassium channel attenuates morphine tolerance by inhibiting jnk and astrocyte activation in the spinal cord. |
2017-03-24 |
2023-08-13 |
Not clear |