| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dong Zhang, Yue Cheng, Kerong Wu, Qi Ma, Junhui Jiang, Zejun Ya. Paroxetine in the treatment of premature ejaculation: a systematic review and meta-analysis. BMC urology. vol 19. issue 1. 2019-05-08. PMID:30606186. |
paroxetine is one of the selective serotonin reuptake inhibitors (ssris) used in the treatment of premature ejaculation (pe). |
2019-05-08 |
2023-08-13 |
Not clear |
| Angela D'Ascola, Giuseppe Bruschetta, Gabriella Zanghì, Salvatore Campo, Pietro Medica, Stefania Campana, Guido Ferlazzo, Bernhard F Gibbs, Alida Maria Ferlazz. Changes in plasma 5-HT levels and equine leukocyte SERT expression in response to treadmill exercise. Research in veterinary science. vol 118. 2019-05-03. PMID:29518708. |
the functionality of sert on leukocytes was investigated by using paroxetine as inhibitor of 5-ht reuptake. |
2019-05-03 |
2023-08-13 |
Not clear |
| Angela D'Ascola, Giuseppe Bruschetta, Gabriella Zanghì, Salvatore Campo, Pietro Medica, Stefania Campana, Guido Ferlazzo, Bernhard F Gibbs, Alida Maria Ferlazz. Changes in plasma 5-HT levels and equine leukocyte SERT expression in response to treadmill exercise. Research in veterinary science. vol 118. 2019-05-03. PMID:29518708. |
flow cytometry revealed that sert is functional in one specific horse leukocyte subpopulation, still not identified, and paroxetine was able to block 5-ht reuptake into leukocytes. |
2019-05-03 |
2023-08-13 |
Not clear |
| Shan-Yan Gao, Qi-Jun Wu, Ce Sun, Tie-Ning Zhang, Zi-Qi Shen, Cai-Xia Liu, Ting-Ting Gong, Xin Xu, Chao Ji, Dong-Hui Huang, Qing Chang, Yu-Hong Zha. Selective serotonin reuptake inhibitor use during early pregnancy and congenital malformations: a systematic review and meta-analysis of cohort studies of more than 9 million births. BMC medicine. vol 16. issue 1. 2019-04-08. PMID:30415641. |
in 2005, the fda cautioned that exposure to paroxetine, a selective serotonin reuptake inhibitor (ssri), during the first trimester of pregnancy may increase the risk of cardiac malformations. |
2019-04-08 |
2023-08-13 |
human |
| Shami Kanekar, Chandni S Sheth, Hendrik J Ombach, Paul R Olson, Olena V Bogdanova, Matthew Petersen, Chloe E Renshaw, Young-Hoon Sung, Kristen E D'Anci, Perry F Rensha. Hypobaric hypoxia exposure in rats differentially alters antidepressant efficacy of the selective serotonin reuptake inhibitors fluoxetine, paroxetine, escitalopram and sertraline. Pharmacology, biochemistry, and behavior. vol 170. 2019-03-22. PMID:29738811. |
hypobaric hypoxia exposure in rats differentially alters antidepressant efficacy of the selective serotonin reuptake inhibitors fluoxetine, paroxetine, escitalopram and sertraline. |
2019-03-22 |
2023-08-13 |
rat |
| Magdalena Kolasa, Joanna Solich, Agata Faron-Górecka, Dariusz Żurawek, Paulina Pabian, Sylwia Łukasiewicz, Maciej Kuśmider, Kinga Szafran-Pilch, Marta Szlachta, Marta Dziedzicka-Wasylewsk. Paroxetine and Low-dose Risperidone Induce Serotonin 5-HT Neuroscience. vol 377. 2019-03-11. PMID:29544901. |
paroxetine and low-dose risperidone induce serotonin 5-ht recently, it has been shown that serotonin 5-ht |
2019-03-11 |
2023-08-13 |
Not clear |
| Tatiana Paschoalin-Maurin, Tayllon Dos Anjos-Garcia, Luiz Luciano Falconi-Sobrinho, Renato Leonardo de Freitas, Jade Pissamiglio Cysne Coimbra, Carlos Júlio Laure, Norberto Cysne Coimbr. The Rodent-versus-wild Snake Paradigm as a Model for Studying Anxiety- and Panic-like Behaviors: Face, Construct and Predictive Validities. Neuroscience. vol 369. 2019-02-21. PMID:29183829. |
mesocricetus auratus was chronically treated with intraperitoneal administration of the selective serotonin uptake inhibitor paroxetine or the gamma aminobutyric acid (gaba)/benzodiazepine receptor agonist alprazolam at three different doses and were then confronted with a venomous coral snake (micrurus frontalis, reptilia, elapidae). |
2019-02-21 |
2023-08-13 |
Not clear |
| Yan Zhang, Futao Liu, Hao Xiao, Xinyue Yao, Genxun Li, Seok Rye Choi, Karl Ploessl, Zhihao Zha, Lin Zhu, Hank F Kun. Fluorine-18 labeled diphenyl sulfide derivatives for imaging serotonin transporter (SERT) in the brain. Nuclear medicine and biology. vol 66. 2019-02-08. PMID:30096380. |
inhibitors of sert binding are well known as selective serotonin reuptake inhibitors (ssris) such as fluoxetine, sertraline, paroxetine, and escitalopram, that are commonly prescribed antidepressants. |
2019-02-08 |
2023-08-13 |
Not clear |
| N Hlavacova, Y Li, A Pehrson, C Sanchez, I Bermudez, A Csanova, D Jezova, M Frankli. Effects of vortioxetine on biomarkers associated with glutamatergic activity in an SSRI insensitive model of depression in female rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 82. 2019-01-22. PMID:29269186. |
the aim of this study was to investigate the antidepressant activity of vortioxetine in a tryptophan (trp) depletion female rat model of depression and compare it to that of paroxetine using doses that fully occupy the serotonin transporter (sert). |
2019-01-22 |
2023-08-13 |
rat |
| Sara I Shafiey, Wafaa R Mohamed, Ali A Abo-Sai. Paroxetine and rivastigmine mitigates adjuvant-induced rheumatoid arthritis in rats: Impact on oxidative stress, apoptosis and RANKL/OPG signals. Life sciences. vol 212. 2018-12-14. PMID:30267788. |
the present study aimed to investigate the anti-rheumatic effects of paroxetine, a selective serotonin reuptake inhibitor (ssri), and rivastigmine, acetyl choline esterase inhibitor (achei), in complete freund's adjuvant (cfa)-induced ra. |
2018-12-14 |
2023-08-13 |
rat |
| Ning Jiang, Lin-Xi Fan, Yu-Jie Yang, Xin-Min Liu, Hai-Ying Lin, Li Gao, Qiong Wan. [Antidepressant effects of the extract of Dendrobium nobile Lindl on chronic unpredictable mild stress-induced depressive mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 69. issue 2. 2018-10-30. PMID:28435974. |
in comparison with the cums group, paroxetine obviously increased the da levels in the hippocampus and the cortex and the 5-ht level in the hippocampus (p < 0.05). |
2018-10-30 |
2023-08-13 |
mouse |
| Goran Arbanas, Tanja Jurin, Vladimir Mozetič, Suzana Mimica Matanović, Josipa Rožman, Dean Markić, Iva Žegur. [THE FIRST CROATIAN GUIDELINES FOR DIAGNOSIS, TREATMENT AND FOLLOW-UP OF PERSONS WITH PREMATURE EJACULATION]. Lijecnicki vjesnik. vol 138. issue 11-12. 2018-09-11. PMID:30148566. |
the first line of treatment is selective serotonin reuptake inhibitors (dapoxetine, which is the only drug with an official label for this indication, paroxetine, sertraline, fluoxetine, citalopram, escitalopram). |
2018-09-11 |
2023-08-13 |
Not clear |
| Naohiro Takeuchi, Shinpei Nonen, Masaki Kato, Masataka Wakeno, Yoshiteru Takekita, Toshihiko Kinoshita, Fumihiko Kugaw. Therapeutic Response to Paroxetine in Major Depressive Disorder Predicted by DNA Methylation. Neuropsychobiology. vol 75. issue 2. 2018-07-27. PMID:29131015. |
approximately 30% of major depressive disorder (mdd) patients do not respond significantly to antidepressants such as paroxetine, a selective serotonin reuptake inhibitor (ssri). |
2018-07-27 |
2023-08-13 |
Not clear |
| Mahyar Etminan, Mohit Sodhi, Ric M Procyshyn, Michael Guo, Bruce C Carleto. Risk of hair loss with different antidepressants: a comparative retrospective cohort study. International clinical psychopharmacology. vol 33. issue 1. 2018-07-18. PMID:28763345. |
the results of this large population-based cohort study suggest an increase in the risk of hair loss with bupropion compared with selective serotonin reuptake inhibitors and selective norepinephrine reuptake inhibitors, whereas paroxetine had the lowest risk. |
2018-07-18 |
2023-08-13 |
Not clear |
| Sandor Kantor, Janos Varga, Shreya Kulkarni, A Jennifer Morto. Chronic Paroxetine Treatment Prevents the Emergence of Abnormal Electroencephalogram Oscillations in Huntington's Disease Mice. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 14. issue 4. 2018-07-17. PMID:28653279. |
to test whether selective serotonin reuptake inhibitors can correct abnormal rem sleep and sleep-dependent brain oscillations in hd mice, we treated wild-type and symptomatic r6/2 mice acutely with vehicle and paroxetine (5, 10, and 20 mg/kg). |
2018-07-17 |
2023-08-13 |
mouse |
| Dawei Xu, Yuyu Sun, Chengniu Wang, Hao Wang, Yingjie Wang, Wei Zhao, Guofeng Bao, Fei Wang, Zhiming Cui, Bo Jian. Hippocampal mTOR signaling is required for the antidepressant effects of paroxetine. Neuropharmacology. vol 128. 2018-07-13. PMID:29030165. |
although thought as a selective serotonin reuptake inhibitor (ssri), the antidepressant mechanisms of paroxetine remain unknown. |
2018-07-13 |
2023-08-13 |
Not clear |
| Wan-Hui Lin, Xiao-Feng Li, Ming-Xing Lin, Ying Zhou, Hua-Pin Huan. Novel insights into the effect of paroxetine administration in pilocarpine‑induced chronic epileptic rats. Molecular medicine reports. vol 16. issue 6. 2018-06-26. PMID:28983622. |
the aim of the present study was to investigate the role of paroxetine intervention in epilepsy, and its association with the expression of serotonin transporter (sert) and hippocampal apoptosis. |
2018-06-26 |
2023-08-13 |
rat |
| Ranko M Kutlesic, Jasmina Popovic, Milan Stefanovic, Predrag Vukomanovic, Bojan Lukic, Goran Lili. ALTERNATIVES OF MENOPAUSAL HORMONE THERAPY. Medicinski pregled. vol 69. issue 5-6. 2018-06-05. PMID:29693846. |
selective serotonin reuptake inhibitors (paroxetine and fluoxetine) and selective noradrenaline reuptake inhibitors (venlafaxine) reduce vasomotor symptoms and improve depression, anxiety and sleep. |
2018-06-05 |
2023-08-13 |
Not clear |
| Shuchi Guo, Rhonda L Carter, Laurel A Grisanti, Walter J Koch, Douglas G Tille. Impact of paroxetine on proximal β-adrenergic receptor signaling. Cellular signalling. vol 38. 2018-05-18. PMID:28711716. |
via structural and biochemical analyses, the selective serotonin reuptake inhibitor (ssri) paroxetine was identified as a grk2 inhibitor that enhances βar-dependent cardiomyocyte and cardiac contractility and reverses cardiac dysfunction and myocardial βar expression in mouse models of heart failure. |
2018-05-18 |
2023-08-13 |
mouse |
| Mona Thapa, Ismene Petrakis, Elizabeth Ralevsk. A Comparison of Sexual Side Effects of Antidepressants With and Without Naltrexone. Journal of dual diagnosis. vol 13. issue 3. 2018-04-23. PMID:28481169. |
the aim of the study was to compare the rate of sexual side effects of the selective serotonin reuptake inhibitor paroxetine versus the tricyclic antidepressant desipramine and to examine the effect of co-prescription of naltrexone on sexual side effects among participants in a randomized clinical trial. |
2018-04-23 |
2023-08-13 |
human |