| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Hébant, M Guillaume, M Desbordes, G Gaillon, D Maltête, R Lefaucheu. Combination of paroxetine and rasagiline induces serotonin syndrome in a parkinsonian patient. Revue neurologique. vol 172. issue 12. 2017-04-11. PMID:27838092. |
combination of paroxetine and rasagiline induces serotonin syndrome in a parkinsonian patient. |
2017-04-11 |
2023-08-13 |
Not clear |
| Heidi Collins Fantasi. A Nonhormonal Treatment for Moderate to Severe Vasomotor Symptoms of Menopause. Nursing for women's health. vol 20. issue 5. 2017-04-04. PMID:27719781. |
in 2013, the u.s. food and drug administration approved paroxetine, a low-dose selective serotonin reuptake inhibitor, as the first nonhormonal treatment for moderate to severe vasomotor symptoms of menopause. |
2017-04-04 |
2023-08-13 |
Not clear |
| Bruce A Davis, Anu Nagarajan, Lucy R Forrest, Satinder K Sing. Mechanism of Paroxetine (Paxil) Inhibition of the Serotonin Transporter. Scientific reports. vol 6. 2017-02-17. PMID:27032980. |
mechanism of paroxetine (paxil) inhibition of the serotonin transporter. |
2017-02-17 |
2023-08-13 |
drosophila_melanogaster |
| Bruce A Davis, Anu Nagarajan, Lucy R Forrest, Satinder K Sing. Mechanism of Paroxetine (Paxil) Inhibition of the Serotonin Transporter. Scientific reports. vol 6. 2017-02-17. PMID:27032980. |
sert has garnered significant clinical attention partly because it is the target of multiple psychoactive agents, including the antidepressant paroxetine (paxil), the most potent selective serotonin reuptake inhibitor known. |
2017-02-17 |
2023-08-13 |
drosophila_melanogaster |
| Wataru Matsuura, Shinichi Harada, Shogo Tokuyam. Effects of Adjuvant Analgesics on Cerebral Ischemia-Induced Mechanical Allodynia. Biological & pharmaceutical bulletin. vol 39. issue 5. 2017-01-27. PMID:27150152. |
by contrast, milnacipran (a serotonin and norepinephrine reuptake inhibitor), paroxetine (selective serotonin reuptake inhibitor), carbamazepine (antiepileptic), and indomethacin (nonsteroidal anti-inflammatory drug) did not affect the bcao-induced mechanical allodynia. |
2017-01-27 |
2023-08-13 |
mouse |
| Yicong Li, Coedy Hadden, Anthonya Cooper, Asli Ahmed, Hong Wu, Vladimir V Lupashin, Philip R Mayeux, Fusun Kili. Sepsis-induced elevation in plasma serotonin facilitates endothelial hyperpermeability. Scientific reports. vol 6. 2017-01-03. PMID:26956613. |
in vivo, reducing the 5-ht uptake rates with the 5-ht transporter (sert) inhibitor, paroxetine blocked renal microvascular leakage and the decline in microvascular perfusion. |
2017-01-03 |
2023-08-13 |
mouse |
| Emily A Karanges, Linnet Ramos, Bruno Dampney, Anastasia S Suraev, Kong M Li, Iain S McGregor, Glenn E Hun. Contrasting regional Fos expression in adolescent and young adult rats following acute administration of the antidepressant paroxetine. Brain research bulletin. vol 121. 2016-12-13. PMID:26876759. |
we used fos immunohistochemistry to examine regional differences in adolescent (postnatal day (pnd) 28) and young adult (pnd 56) male, wistar rats given a single injection of the selective serotonin reuptake inhibitor paroxetine (10mg/kg). |
2016-12-13 |
2023-08-13 |
rat |
| Ronald S Oosting, Johnny S Chan, Berend Olivier, Pradeep Banerjee, Yong Kee Choi, Frank Taraz. Differential effects of vilazodone versus citalopram and paroxetine on sexual behaviors and serotonin transporter and receptors in male rats. Psychopharmacology. vol 233. issue 6. 2016-10-12. PMID:26758283. |
differential effects of vilazodone versus citalopram and paroxetine on sexual behaviors and serotonin transporter and receptors in male rats. |
2016-10-12 |
2023-08-13 |
rat |
| Yogendra Raj Pandey, Shobhit Kumar, Bijay Kumar Gupta, Javed Ali, Sanjula Baboot. Intranasal delivery of paroxetine nanoemulsion via the olfactory region for the management of depression: formulation, behavioural and biochemical estimation. Nanotechnology. vol 27. issue 2. 2016-10-05. PMID:26629830. |
paroxetine is a selective serotonin reuptake inhibitor (ssri) and is used for the treatment of depression and anxiety problems, but suffers from the drawback of poor oral bioavailability (less than 50%) due to its extensive first pass metabolism. |
2016-10-05 |
2023-08-13 |
rat |
| Vishal Bali, Satabdi Chatterjee, Ryan M Carnahan, Hua Chen, Michael L Johnson, Rajender R Aparas. Risk of Dementia Among Elderly Nursing Home Patients Using Paroxetine and Other Selective Serotonin Reuptake Inhibitors. Psychiatric services (Washington, D.C.). vol 66. issue 12. 2016-09-21. PMID:26234334. |
risk of dementia among elderly nursing home patients using paroxetine and other selective serotonin reuptake inhibitors. |
2016-09-21 |
2023-08-13 |
Not clear |
| Shin-Ichi Hisasu. The drug treatment of premature ejaculation. Translational andrology and urology. vol 5. issue 4. 2016-09-21. PMID:27652221. |
for the drug treatment for pe, gold standard is selective serotonin reuptake inhibitors (ssris) including dapoxetine or paroxetine. |
2016-09-21 |
2023-08-13 |
Not clear |
| Yoshikazu Nikaido, Junko Yamada, Keisuke Migita, Yuko Shiba, Tomonori Furukawa, Toshihiro Nakashima, Shinya Uen. cis-3-Hexenol and trans-2-hexenal mixture prevents development of PTSD-like phenotype in rats. Behavioural brain research. vol 297. 2016-09-20. PMID:26475511. |
to further investigate the mechanism of effect of go, we examined the effect of paroxetine (a selective serotonin reuptake inhibitor), p-chlorophenylalanine (pcpa, an irreversible serotonin synthesis inhibitor), alone or in combination of go on ptsd-like phenotype. |
2016-09-20 |
2023-08-13 |
rat |
| Russell J Lewis, Philip M Kemp, Robert D Johnso. Paroxetine in Postmortem Fluids and Tissues from Nine Aviation Accident Victims. Journal of analytical toxicology. vol 39. issue 8. 2016-09-09. PMID:26378138. |
paroxetine is a selective serotonin reuptake inhibitor commonly prescribed for the treatment of depression, obsessive-compulsive disorder, panic disorder, social anxiety disorder and post-traumatic stress disorder. |
2016-09-09 |
2023-08-13 |
Not clear |
| Kristin Feltmann, Åsa Konradsson-Geuken, Dimitri De Bundel, Maria Lindskog, Björn Schilströ. Antidepressant drugs specifically inhibiting noradrenaline reuptake enhance recognition memory in rats. Behavioral neuroscience. vol 129. issue 6. 2016-09-01. PMID:26501179. |
in contrast, the serotonin reuptake inhibitors citalopram and paroxetine and the cyclic antidepressant drugs desipramine and mianserin did not enhance recognition memory. |
2016-09-01 |
2023-08-13 |
rat |
| Heather Kovich, Amanda DeJon. Common Questions About the Pharmacologic Management of Depression in Adults. American family physician. vol 92. issue 2. 2016-08-17. PMID:26176368. |
it is unclear whether selective serotonin reuptake inhibitor use in breastfeeding mothers causes adverse effects in their infants, but sertraline and paroxetine transfer to breast milk in lower concentrations than other antidepressants. |
2016-08-17 |
2023-08-13 |
Not clear |
| Masaki Iwai, Yoshikage Muroi, Ken-ichi Kinoshita, Toshiaki Ishi. Serotonin modulates the dehydration-induced changes in tolerance for bitter water. Physiology & behavior. vol 151. 2016-06-28. PMID:26325013. |
moreover, administration of paroxetine, a selective serotonin reuptake inhibitor, decreased the intake of quinine solution, but not water, in mice deprived of water for 48 h, indicating that paroxetine treatment restored the aversion to quinine. |
2016-06-28 |
2023-08-13 |
mouse |
| Shigeru Hasebe, Yukio Ago, Saki Nishiyama, Satoshi Oka, Hitoshi Hashimoto, Kazuhiro Takuma, Toshio Matsud. Pharmacological profile of encounter-induced hyperactivity in isolation-reared mice. Behavioural pharmacology. vol 26. issue 7 Spec No. 2016-05-25. PMID:25932719. |
encounter-induced hyperactivity was reduced by acute administration of various antidepressants including the tricyclic antidepressant desipramine (10 mg/kg), the selective serotonin (5-ht) reuptake inhibitors fluvoxamine (10 mg/kg) and paroxetine (10 mg/kg), the 5-ht/noradrenaline reuptake inhibitors venlafaxine (10 mg/kg) and duloxetine (10 mg/kg), the antipsychotic drug risperidone (0.01 mg/kg), the 5-ht2 antagonist ritanserin (1 mg/kg), and the glucocorticoid receptor antagonist ru-43044 (30 mg/kg). |
2016-05-25 |
2023-08-13 |
mouse |
| Lisa N Kransdorf, Melissa A McNeil, Julia A Files, Marjorie R Jenkin. Women's health 2015: an update for the internist. Cleveland Clinic journal of medicine. vol 82. issue 11. 2016-04-26. PMID:26540326. |
major studies in 2014 and the first half of 2015 suggest that selective serotonin reuptake inhibitors are not strongly associated with congenital heart defects, that paroxetine 7.5 mg is effective for treating menopausal symptoms, and that women with heart failure may benefit more from cardiac resynchronization therapy than men. |
2016-04-26 |
2023-08-13 |
Not clear |
| Yu Guo, You Wang, Xi Wang, Gang Ye, Yuanbin Jiang, Wei Xion. Association Between Changes in Serum 5-Hydroxy-Tryptamine Concentrations and Improvement in Clinical Symptoms in Primary Premature Ejaculation with Paroxetine Treatment. Medical science monitor : international medical journal of experimental and clinical research. vol 21. 2016-04-22. PMID:26305631. |
this study aimed to investigate the association between changes in serum 5-hydroxy tryptamine (5-ht) concentrations and improvement in clinical symptoms in primary premature ejaculation with paroxetine treatment. |
2016-04-22 |
2023-08-13 |
Not clear |
| Sylvain Chassang, Erik Snowberg, Ben Seymour, Cayley Bowle. Accounting for Behavior in Treatment Effects: New Applications for Blind Trials. PloS one. vol 10. issue 6. 2016-03-15. PMID:26062024. |
out of six eligible studies, which included three for the selective serotonin re-uptake inhibitor paroxetine, and three for the tricyclic imipramine, three studies had a high (>65%) probability of treatment. |
2016-03-15 |
2023-08-13 |
human |