| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Robert D Oades, Michael Slusarek, Silke Velling, Brigitta Bond. Serotonin platelet-transporter measures in childhood attention-deficit/hyperactivity disorder (ADHD): clinical versus experimental measures of impulsivity. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 3. issue 2. 2003-01-23. PMID:12479082. |
here, we explored in 20 children with adhd the relationship of the density (bmax) and affinity (kd) of the platelet 5-ht transporter measured with [3h]paroxetine to both clinical ratings of impulsivity (conners' parent questionnaire), and an experimental measure of impulsivity (the ability to withhold a prepotent response in the "stop-signal" paradigm). |
2003-01-23 |
2023-08-12 |
Not clear |
| Heather J Chial, Michael Camilleri, Duane Burton, George Thomforde, Kevin W Olden, Debra Stephen. Selective effects of serotonergic psychoactive agents on gastrointestinal functions in health. American journal of physiology. Gastrointestinal and liver physiology. vol 284. issue 1. 2003-01-23. PMID:12488239. |
participants received one of four regimens in a randomized, double-blind manner: buspirone, a 5-ht(1a) receptor agonist (10 mg twice daily); paroxetine, a selective serotonin reuptake inhibitor (20 mg daily); venlafaxine-xr, a selective serotonin and norepinephrine reuptake inhibitor (75 mg daily); or placebo for 11 days. |
2003-01-23 |
2023-08-12 |
human |
| Ashwin A Patkar, Charles C Thornton, Wade H Berrettini, Edward Gottheil, Stephen P Weinstein, Kevin P Hil. Predicting treatment-outcome in cocaine dependence from admission urine drug screen and peripheral serotonergic measures. Journal of substance abuse treatment. vol 23. issue 1. 2003-01-16. PMID:12127466. |
we investigated whether urine drug screens (uds) at admission and platelet paroxetine binding, a measure of serotonin transporter sites, were related to outcome measures for cocaine patients in treatment. |
2003-01-16 |
2023-08-12 |
Not clear |
| Ashwin A Patkar, Charles C Thornton, Wade H Berrettini, Edward Gottheil, Stephen P Weinstein, Kevin P Hil. Predicting treatment-outcome in cocaine dependence from admission urine drug screen and peripheral serotonergic measures. Journal of substance abuse treatment. vol 23. issue 1. 2003-01-16. PMID:12127466. |
a significant association was found between cocaine-positive uds at admission and negative urines, treatment retention, dropouts, and treatment sessions; while bmax values of paroxetine binding (density of serotonin transporter sites) were significantly associated with treatment retention and negative urines. |
2003-01-16 |
2023-08-12 |
Not clear |
| Martin B Kelle. Rationale and options for the long-term treatment of depression. Human psychopharmacology. vol 17 Suppl 1. 2003-01-13. PMID:12404670. |
mirtazapine has shown sustained efficacy in the long-term treatment of depression, being more effective than amitriptyline and at least as effective as the selective serotonin reuptake inhibitors paroxetine and citalopram. |
2003-01-13 |
2023-08-12 |
Not clear |
| C K Olsen, S Hogg, M D S Lapi. Tonic immobility in guinea pigs: a behavioural response for detecting an anxiolytic-like effect? Behavioural pharmacology. vol 13. issue 4. 2002-12-24. PMID:12218506. |
the selective 5-ht reuptake inhibitors citalopram, paroxetine and fluoxetine, the 5-ht(1a) receptor antagonist way100.635, the 5-ht(2c) receptor agonist mk-212, the 5-ht/na reuptake inhibitor imipramine, the na reuptake inhibitor talopram, the benzodiazepine antagonist flumazenil, the alpha(2)-adrenergic receptor antagonist idazoxan and the psychostimulant amphetamine did not have any effect. |
2002-12-24 |
2023-08-12 |
Not clear |
| M E Sewnath, R van Hillegersberg, M M W Koopman, M M Levi, D J Goum. [Increased perioperative blood loss during treatment with paroxetine]. Nederlands tijdschrift voor geneeskunde. vol 146. issue 38. 2002-12-17. PMID:12369443. |
paroxetine is a non-tricyclic serotonin reuptake inhibitor prescribed for the treatment of depression. |
2002-12-17 |
2023-08-12 |
Not clear |
| Francesca Fernandez, Sylvie Aguerre, Pierre Mormède, Francis Chaoulof. Influences of the corticotropic axis and sympathetic activity on neurochemical consequences of 3,4-methylenedioxymethamphetamine (MDMA) administration in Fischer 344 rats. The European journal of neuroscience. vol 16. issue 4. 2002-11-22. PMID:12270036. |
the respective influences of the corticotropic axis and sympathetic activity on 3,4-methylenedioxymethamphetamine (mdma, ecstasy) immediate effects on body temperature and long-term neurotoxicity, as assessed by decreases in hippocampal and striatal [(3)h]5-hydroxytryptamine ([(3)h]5-ht) reuptake, [(3)h]paroxetine binding at 5-ht transporters (5-htt), and 5-ht and 5-hydroxyindoleacetic acid (5-hiaa) levels, were examined in fischer 344 rats. |
2002-11-22 |
2023-08-12 |
rat |
| Francesca Fernandez, Sylvie Aguerre, Pierre Mormède, Francis Chaoulof. Influences of the corticotropic axis and sympathetic activity on neurochemical consequences of 3,4-methylenedioxymethamphetamine (MDMA) administration in Fischer 344 rats. The European journal of neuroscience. vol 16. issue 4. 2002-11-22. PMID:12270036. |
six days after the last injection of 10 mg/kg mdma, [(3)h]5-ht reuptake, [(3)h]paroxetine binding and 5-ht and 5-hiaa levels were decreased in the hippocampus and, to a lower extent, in striatum. |
2002-11-22 |
2023-08-12 |
rat |
| Francesca Fernandez, Sylvie Aguerre, Pierre Mormède, Francis Chaoulof. Influences of the corticotropic axis and sympathetic activity on neurochemical consequences of 3,4-methylenedioxymethamphetamine (MDMA) administration in Fischer 344 rats. The European journal of neuroscience. vol 16. issue 4. 2002-11-22. PMID:12270036. |
this pretreatment markedly reduced the amplitudes of the immediate hyperthermia and long-term declines in hippocampal [(3)h]5-ht reuptake and [(3)h]paroxetine binding at 5-htt, and in hippocampal and striatal 5-ht and 5-hiaa levels. |
2002-11-22 |
2023-08-12 |
rat |
| Marilyn J Duncan, Julie G Hensle. Aging alters in a region-specific manner serotonin transporter sites and 5-HT(1A) receptor-G protein interactions in hamster brain. Neuropharmacology. vol 43. issue 1. 2002-11-21. PMID:12213257. |
an age-related decrease in the maximal density of serotonin transporter sites labelled with [(3)h]paroxetine (fmol/mg protein, old: 396+/-13; young: 487+/-27) was observed in the dorsal raphe nucleus (drn) but not the median raphe nucleus (mrn), without affecting the affinity of [(3)h]paroxetine. |
2002-11-21 |
2023-08-12 |
Not clear |
| Mary C Wolff, J David Leande. Selective serotonin reuptake inhibitors decrease impulsive behavior as measured by an adjusting delay procedure in the pigeon. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 27. issue 3. 2002-11-15. PMID:12225699. |
chronic (17 day), but not acute injections of the selective serotonin reuptake inhibitors (ssris) fluoxetine (10 mg/kg), citalopram (10 mg/kg) and paroxetine (3 mg/kg) increased the delay period. |
2002-11-15 |
2023-08-12 |
pigeon |
| Bernardo Ng, Wayne A Bardwell, Alvaro Camach. Depression treatment in rural California: preliminary survey of nonpsychiatric physicians. The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association. vol 18. issue 4. 2002-11-08. PMID:12380898. |
the most commonly prescribed drugs were selective serotonin reuptake inhibitors (in order of frequency:fluoxetine, sertraline, and paroxetine). |
2002-11-08 |
2023-08-12 |
Not clear |
| David J Rademacher, Anthony P Anderson, Rhea E Steinprei. Acute effects of amperozide and paroxetine on social cohesion in male conspecifics. Brain research bulletin. vol 58. issue 2. 2002-11-06. PMID:12127016. |
the effects of acute administration of the selective 5-hydroxytrypamine (5-ht; serotonin) uptake inhibitor, paroxetine, and the potent 5-ht(2a) receptor antagonist, n-ethyl-4-[4',4'-bis(rho-flourophenyl)butyl]-1-piperazinecarboxamide (amperozide) on social cohesion was determined by using a tether paradigm, in which the movement of one of a pair of rats was restricted to one-half of an observation chamber. |
2002-11-06 |
2023-08-12 |
rat |
| Barry E Levin, Ambrose A Dunn-Meynel. Maternal obesity alters adiposity and monoamine function in genetically predisposed offspring. American journal of physiology. Regulatory, integrative and comparative physiology. vol 283. issue 5. 2002-11-06. PMID:12376402. |
after 12 wk on chow and 4 wk on a 31% fat diet, offspring hypothalamic nucleus size and [(3)h]nisoxetine binding to norepinephrine transporters (net) and [(3)h]paroxetine binding to serotonin transporters (set) were measured. |
2002-11-06 |
2023-08-12 |
Not clear |
| Jesús M Míguez, Lucinda Paz-Valiñas, Isabel Míguez, Manuel Aldegund. Somatodendritic action of pindolol to attenuate the paroxetine-induced decrease in serotonin release from the rat ventral hippocampus: a microdialysis study. Naunyn-Schmiedeberg's archives of pharmacology. vol 365. issue 5. 2002-11-04. PMID:12012024. |
we used intracerebral microdialysis to study the role of raphe and presynaptic serotonin (5-ht) autoreceptors in the effect of the selective 5-ht reuptake inhibitor, paroxetine, on 5-ht release from ventral hippocampus of anaesthetised rats. |
2002-11-04 |
2023-08-12 |
rat |
| Jesús M Míguez, Lucinda Paz-Valiñas, Isabel Míguez, Manuel Aldegund. Somatodendritic action of pindolol to attenuate the paroxetine-induced decrease in serotonin release from the rat ventral hippocampus: a microdialysis study. Naunyn-Schmiedeberg's archives of pharmacology. vol 365. issue 5. 2002-11-04. PMID:12012024. |
in addition, we have tested the ability of pindolol, a non-selective beta-adrenergic/5-ht(1a) receptor antagonist, to alter the response of hippocampal 5-ht to paroxetine. |
2002-11-04 |
2023-08-12 |
rat |
| Jesús M Míguez, Lucinda Paz-Valiñas, Isabel Míguez, Manuel Aldegund. Somatodendritic action of pindolol to attenuate the paroxetine-induced decrease in serotonin release from the rat ventral hippocampus: a microdialysis study. Naunyn-Schmiedeberg's archives of pharmacology. vol 365. issue 5. 2002-11-04. PMID:12012024. |
doses of paroxetine with maximal effects were near to three-fold less effective when administered systemically than after local infusion at increasing extracellular 5-ht in ventral hippocampus. |
2002-11-04 |
2023-08-12 |
rat |
| Jesús M Míguez, Lucinda Paz-Valiñas, Isabel Míguez, Manuel Aldegund. Somatodendritic action of pindolol to attenuate the paroxetine-induced decrease in serotonin release from the rat ventral hippocampus: a microdialysis study. Naunyn-Schmiedeberg's archives of pharmacology. vol 365. issue 5. 2002-11-04. PMID:12012024. |
moreover, systemic paroxetine treatment resulted in a marked decrease of the extracellular 5-ht in the hippocampus when 5-ht reuptake was blocked with paroxetine 3 microm applied locally, thereby evidencing that systemic treatment induced a decrease of 5-ht release in the neuronal terminal. |
2002-11-04 |
2023-08-12 |
rat |
| Jesús M Míguez, Lucinda Paz-Valiñas, Isabel Míguez, Manuel Aldegund. Somatodendritic action of pindolol to attenuate the paroxetine-induced decrease in serotonin release from the rat ventral hippocampus: a microdialysis study. Naunyn-Schmiedeberg's archives of pharmacology. vol 365. issue 5. 2002-11-04. PMID:12012024. |
in addition, the infusion into median raphe of (-)-pindolol, the isoform with highest antagonist activity, at concentrations of 10 microm and 100 microm was able to partially block the decrease of hippocampal 5-ht release after systemic paroxetine. |
2002-11-04 |
2023-08-12 |
rat |