| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anaïs Le Mauff, Hamza Chouikh, Alison Cartereau, Claude L Charvet, Cédric Neveu, Claude Rispe, Olivier Plantard, Emiliane Taillebois, Steeve H Than. Nicotinic acetylcholine receptors in the synganglion of the tick Ixodes ricinus: Functional characterization using membrane microtransplantation. International journal for parasitology. Drugs and drug resistance. vol 14. 2021-08-20. PMID:33120248. |
we found that oocytes microtransplanted with tick synganglion membranes expressed nicotinic acetylcholine receptor subtypes which were activated by acetylcholine (1 mm) and nicotine (1 mm). |
2021-08-20 |
2023-08-13 |
xenopus_laevis |
| Anaïs Le Mauff, Hamza Chouikh, Alison Cartereau, Claude L Charvet, Cédric Neveu, Claude Rispe, Olivier Plantard, Emiliane Taillebois, Steeve H Than. Nicotinic acetylcholine receptors in the synganglion of the tick Ixodes ricinus: Functional characterization using membrane microtransplantation. International journal for parasitology. Drugs and drug resistance. vol 14. 2021-08-20. PMID:33120248. |
currents induced by pressure application of acetylcholine and nicotine were diminished by 10 nm α-bungarotoxin and methyllycaconitine, suggesting that they expressed two subtypes of nicotinic receptors, α-bungarotoxin-sensitive and -insensitive, respectively. |
2021-08-20 |
2023-08-13 |
xenopus_laevis |
| Anna K Whitehead, Abigail P Erwin, Xinping Yu. Nicotine and vascular dysfunction. Acta physiologica (Oxford, England). vol 231. issue 4. 2021-08-18. PMID:33595878. |
this review summarizes our current knowledge of the expression and function of the nicotinic acetylcholine receptors in the cardiovascular system and the impact of nicotine exposure on cardiovascular health, with a focus on nicotine-induced vascular dysfunction. |
2021-08-18 |
2023-08-13 |
Not clear |
| Ruthie E Wittenberg, Shannon L Wolfman, Mariella De Biasi, John A Dan. Nicotinic acetylcholine receptors and nicotine addiction: A brief introduction. Neuropharmacology. vol 177. 2021-08-12. PMID:32738308. |
nicotinic acetylcholine receptors and nicotine addiction: a brief introduction. |
2021-08-12 |
2023-08-13 |
Not clear |
| Ruthie E Wittenberg, Shannon L Wolfman, Mariella De Biasi, John A Dan. Nicotinic acetylcholine receptors and nicotine addiction: A brief introduction. Neuropharmacology. vol 177. 2021-08-12. PMID:32738308. |
nicotine binds to neuronal nicotinic acetylcholine receptors (nachrs), which come in a diverse collection of subtypes. |
2021-08-12 |
2023-08-13 |
Not clear |
| Lauren C Smith, Olivier Georg. Advances in smoking cessation pharmacotherapy: Non-nicotinic approaches in animal models. Neuropharmacology. vol 178. 2021-08-12. PMID:32758566. |
nicotine replacement therapy and varenicline both act on nicotinic acetylcholine receptors. |
2021-08-12 |
2023-08-13 |
Not clear |
| Lauren C Smith, Olivier Georg. Advances in smoking cessation pharmacotherapy: Non-nicotinic approaches in animal models. Neuropharmacology. vol 178. 2021-08-12. PMID:32758566. |
recent pharmacological approaches to improve nicotine cessation rates in animal models have turned their focus away from activating nicotinic acetylcholine receptors. |
2021-08-12 |
2023-08-13 |
Not clear |
| Yuka Kasahara, Daiki Masukawa, Yoshie Nakamura, Koshi Murata, Tatsuo Hashimoto, Kohtaro Takizawa, Motokazu Koga, Fumio Nakamura, Yugo Fukazawa, Kengo Funakoshi, Yoshio Goshim. Distribution of mRNA for GPR143, a receptor of 3,4-L-dihydroxyphenylalanine, and of immunoreactivities for nicotinic acetylcholine receptors in the nigrostriatal and mesolimbic regions. Neuroscience research. vol 170. 2021-08-04. PMID:32896531. |
nicotine exerts its reinforcing actions by activating nicotinic acetylcholine receptors (nachrs), but the detailed mechanisms remain unclear. |
2021-08-04 |
2023-08-13 |
Not clear |
| Alireza Majdi, Saeed Sadigh-Eteghad, Albert Gjedd. Effects of transdermal nicotine delivery on cognitive outcomes: A meta-analysis. Acta neurologica Scandinavica. vol 144. issue 2. 2021-07-19. PMID:33899218. |
by the association of nicotinic acetylcholine receptors in the brain, nicotine in the therapeutic window lowers neuronal damage and raises protective factors. |
2021-07-19 |
2023-08-13 |
Not clear |
| Yuan-Bing Huang, Ze-Gang Ma, Chao Zheng, Xiao-Kuang K Ma, Devin H Taylor, Ming Gao, Ronald J Lukas, Jie W. Levo-tetrahydropalmatine inhibits α4β2 nicotinic receptor response to nicotine in cultured SH-EP1 cells. Acta pharmacologica Sinica. 2021-07-13. PMID:34253876. |
nicotine, a major component of tobacco, is highly addictive and acts on nicotinic acetylcholine receptors (nachrs) to stimulate reward-associated circuits in the brain. |
2021-07-13 |
2023-08-13 |
human |
| Martin A Fuentes-Cano, Dulce J Bustamante-Valdez, Pilar Durá. Perinatal exposure to nicotine disrupts circadian locomotor and learning efficiency rhythms in juvenile mice. Brain structure & function. vol 225. issue 7. 2021-07-06. PMID:32789697. |
nicotine, as an alkaloid, alters the reward system acting as acetylcholine (ach) agonist on nicotinic cholinergic receptors (nachrs). |
2021-07-06 |
2023-08-13 |
mouse |
| E Carstens E, M Iodi Carsten. Sensory effects of nicotine and tobacco. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2021-07-02. PMID:33955474. |
nicotine elicits oral irritation and pain via the activation of neuronal nicotinic acetylcholine receptors (nachrs) expressed by trigeminal nociceptors. |
2021-07-02 |
2023-08-13 |
human |
| Hirohito Esaki, Shoma Izumi, Akari Fukao, Shiho Ito, Naoya Nishitani, Satoshi Deyama, Katsuyuki Kaned. Nicotine Enhances Object Recognition Memory via Stimulating α4β2 and α7 Nicotinic Acetylcholine Receptors in the Medial Prefrontal Cortex of Mice. Biological & pharmaceutical bulletin. vol 44. issue 7. 2021-07-01. PMID:34193682. |
nicotine enhances object recognition memory via stimulating α4β2 and α7 nicotinic acetylcholine receptors in the medial prefrontal cortex of mice. |
2021-07-01 |
2023-08-13 |
mouse |
| A Alhowai. Varenicline enhances the survival of doxorubicin-treated mice. European review for medical and pharmacological sciences. vol 24. issue 21. 2021-06-28. PMID:33215455. |
nicotine has been shown to inhibit dox-induced cytotoxicity in vitro by activating nicotinic acetylcholine receptors. |
2021-06-28 |
2023-08-13 |
mouse |
| Mina Afrashteh Nour, Khalil Hajiasgharzadeh, Fatemeh Kheradmand, Zahra Asadzadeh, Nadia Bolandi, Behzad Baradara. Nicotinic acetylcholine receptors in chemotherapeutic drugs resistance: An emerging targeting candidate. Life sciences. vol 278. 2021-06-24. PMID:33930371. |
nicotine as a component of cigarette smoke is an exogenous activator of nicotinic acetylcholine receptors (nachrs). |
2021-06-24 |
2023-08-13 |
Not clear |
| Roberto Cuevas-Olguin, Eric Esquivel-Rendon, Jorge Vargas-Mireles, Carlos Barajas-Lόpez, Roberto Salgado-Delgado, Nadia Saderi, Hugo R Arias, Marco Atzori, Marcela Miranda-Morale. Nicotine smoking concentrations modulate GABAergic synaptic transmission in murine medial prefrontal cortex by activation of α7* and β2* nicotinic receptors. The European journal of neuroscience. vol 51. issue 3. 2021-06-21. PMID:31613395. |
we used patch clamp in vitro recording from c57bl/6 mice in the whole-cell configuration to investigate the effect of nicotine on pharmacologically isolated gabaergic postsynaptic currents (ipscs) in the absence or presence of methyllycaconitine (mla) or dihydro-β-erythroidine (dhβe), selective antagonists of α7- and β2-containing (α7* and β2*) nicotinic acetylcholine receptors (achrs), respectively. |
2021-06-21 |
2023-08-13 |
mouse |
| Xiao-Tao Jin, Brenton R Tucker, Ryan M Drena. Nicotine Self-Administration Induces Plastic Changes to Nicotinic Receptors in Medial Habenula. eNeuro. vol 7. issue 4. 2021-06-18. PMID:32675176. |
chronic nicotine upregulates nicotinic acetylcholine receptors (nachrs) throughout the brain, and reducing their activity may promote somatic and affective states that lead to nicotine seeking. |
2021-06-18 |
2023-08-13 |
rat |
| Xiao-Tao Jin, Brenton R Tucker, Ryan M Drena. Nicotine Self-Administration Induces Plastic Changes to Nicotinic Receptors in Medial Habenula. eNeuro. vol 7. issue 4. 2021-06-18. PMID:32675176. |
using patch-clamp whole-cell recordings and local application of acetylcholine, we observed robust functional enhancement of nachrs in mhb neurons from rats with a history of nicotine sa. |
2021-06-18 |
2023-08-13 |
rat |
| Ekaterina Morozova, Philippe Faure, Boris Gutkin, Christoper Lapish, Alexey Kuznetso. Distinct Temporal Structure of Nicotinic ACh Receptor Activation Determines Responses of VTA Neurons to Endogenous ACh and Nicotine. eNeuro. vol 7. issue 4. 2021-06-18. PMID:32737187. |
the addictive component of tobacco, nicotine, acts via nicotinic acetylcholine receptors (nachrs). |
2021-06-18 |
2023-08-13 |
Not clear |
| Austin T Akers, Skylar Y Cooper, Zachary J Baumgard, Gabriella P Casinelli, Alicia J Avelar, Brandon J Henderso. Upregulation of nAChRs and Changes in Excitability on VTA Dopamine and GABA Neurons Correlates to Changes in Nicotine-Reward-Related Behavior. eNeuro. vol 7. issue 5. 2021-06-18. PMID:32988984. |
previous reports indicate that nicotine reward is mediated through α4β2*, α6β2*, and α4α6β2* nicotinic acetylcholine receptors (nachrs; * indicates that additional nachr subunits may be present). |
2021-06-18 |
2023-08-13 |
mouse |