| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Corentin Le Magueresse, Enrico Cherubin. Presynaptic calcium stores contribute to nicotine-elicited potentiation of evoked synaptic transmission at CA3-CA1 connections in the neonatal rat hippocampus. Hippocampus. vol 17. issue 4. 2007-06-13. PMID:17330864. |
nicotine acetylcholine (ach) receptors (nachrs) are ligand-gated ion channels that are widely expressed throughout the central nervous system. |
2007-06-13 |
2023-08-12 |
rat |
| Virginie Arnaud, Michel Berthelot, Michel Evain, Jérôme Graton, Jean-Yves Le Queste. Hydrogen-bond interactions of nicotine and acetylcholine salts: a combined crystallographic, spectroscopic, thermodynamic and theoretical study. Chemistry (Weinheim an der Bergstrasse, Germany). vol 13. issue 5. 2007-06-12. PMID:17103466. |
hydrogen-bond interactions of nicotine and acetylcholine salts: a combined crystallographic, spectroscopic, thermodynamic and theoretical study. |
2007-06-12 |
2023-08-12 |
Not clear |
| Virginie Arnaud, Michel Berthelot, Michel Evain, Jérôme Graton, Jean-Yves Le Queste. Hydrogen-bond interactions of nicotine and acetylcholine salts: a combined crystallographic, spectroscopic, thermodynamic and theoretical study. Chemistry (Weinheim an der Bergstrasse, Germany). vol 13. issue 5. 2007-06-12. PMID:17103466. |
the hydrogen-bond (hb) interactions of the monocharged active forms of nicotine and acetylcholine (ach) have been compared theoretically by using density functional theory (dft) calculations and experimentally on the basis of crystallographic observations and the measurement of equilibrium constants in solution. |
2007-06-12 |
2023-08-12 |
Not clear |
| Morgane Besson, Sylvie Granon, Monica Mameli-Engvall, Isabelle Cloëz-Tayarani, Nicolas Maubourguet, Anne Cormier, Pierre Cazala, Vincent David, Jean-Pierre Changeux, Philippe Faur. Long-term effects of chronic nicotine exposure on brain nicotinic receptors. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 19. 2007-06-07. PMID:17470777. |
chronic nicotine exposure results in long-term homeostatic regulation of nicotinic acetylcholine receptors (nachrs) that play a key role in the adaptative cellular processes leading to addiction. |
2007-06-07 |
2023-08-12 |
mouse |
| Theodore A Slotkin, Emiko A MacKillop, Charles L Rudder, Ian T Ryde, Charlotte A Tate, Frederic J Seidle. Permanent, sex-selective effects of prenatal or adolescent nicotine exposure, separately or sequentially, in rat brain regions: indices of cholinergic and serotonergic synaptic function, cell signaling, and neural cell number and size at 6 months of age. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 5. 2007-06-05. PMID:17047666. |
we assessed the permanence of effects in rats on indices of neural cell number and size, and on acetylcholine and serotonin (5ht) systems, conducting assessments at 6 months of age, after prenatal nicotine exposure, adolescent exposure, or sequential exposure in both periods. |
2007-06-05 |
2023-08-12 |
rat |
| Matthew I Palmatier, Xiu Liu, Anthony R Caggiula, Eric C Donny, Alan F Sve. The role of nicotinic acetylcholine receptors in the primary reinforcing and reinforcement-enhancing effects of nicotine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 5. 2007-06-05. PMID:17091131. |
the role of nicotinic acetylcholine receptors in the primary reinforcing and reinforcement-enhancing effects of nicotine. |
2007-06-05 |
2023-08-12 |
rat |
| Matthew I Palmatier, Xiu Liu, Anthony R Caggiula, Eric C Donny, Alan F Sve. The role of nicotinic acetylcholine receptors in the primary reinforcing and reinforcement-enhancing effects of nicotine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 5. 2007-06-05. PMID:17091131. |
the primary reinforcing effects of nicotine are mediated by the drugs action at central nervous system nicotinic acetylcholine receptors (nachrs). |
2007-06-05 |
2023-08-12 |
rat |
| Jonathan J Couey, Rhiannon M Meredith, Sabine Spijker, Rogier B Poorthuis, August B Smit, Arjen B Brussaard, Huibert D Mansvelde. Distributed network actions by nicotine increase the threshold for spike-timing-dependent plasticity in prefrontal cortex. Neuron. vol 54. issue 1. 2007-06-01. PMID:17408579. |
nicotine enhances attention and working memory by activating nicotinic acetylcholine receptors (nachrs). |
2007-06-01 |
2023-08-12 |
mouse |
| N H Kleinsasser, A W Sassen, M P Semmler, R Staudenmaier, U A Harréus, E Richte. [Does nicotine add to the carcinogenic strain of tobacco smoke?]. HNO. vol 54. issue 5. 2007-05-30. PMID:16170509. |
it is accepted that nicotine in tobacco smoke causes addiction via nicotinic acetylcholine receptors in the central nervous system. |
2007-05-30 |
2023-08-12 |
human |
| N H Kleinsasser, A W Sassen, M P Semmler, R Staudenmaier, U A Harréus, E Richte. [Does nicotine add to the carcinogenic strain of tobacco smoke?]. HNO. vol 54. issue 5. 2007-05-30. PMID:16170509. |
however, more recently data have accumulated which suggest that nicotine may add to the cancer risk by stimulating cellular growth via non-neuronal acetylcholine receptors, by suppressing apoptosis, and by inducing angiogenesis not only in atheromatous plaques but also in tumors. |
2007-05-30 |
2023-08-12 |
human |
| Roger L Papke, Linda P Dwoskin, Peter A Crook. The pharmacological activity of nicotine and nornicotine on nAChRs subtypes: relevance to nicotine dependence and drug discovery. Journal of neurochemistry. vol 101. issue 1. 2007-05-29. PMID:17241116. |
we have now examined the effects of nornicotine on specific combinations of neuronal nicotinic acetylcholine receptor (nachr) subunits expressed in xenopus oocytes and compared these responses to those evoked by acetylcholine and nicotine. |
2007-05-29 |
2023-08-12 |
xenopus_laevis |
| Sevil Ozger Ilhan, Ismail Mert Vural, Ergin Dileköz, Gökçe Sevim Oztürk, Yusuf Sariogl. Enhancement effects of nicotine on neurogenic contractile responses in rabbit gastric fundus. European journal of pharmacology. vol 561. issue 1-3. 2007-05-22. PMID:17292347. |
we aimed to investigate the effects of nicotine on neurogenic contractile responses via nicotinic acetylcholine receptors and, if a change occurred, to investigate the effects of n(w)-nitro-l-arginine methyl ester (l-name) and indomethacin on this change in rabbit gastric fundus. |
2007-05-22 |
2023-08-12 |
rabbit |
| Sevil Ozger Ilhan, Ismail Mert Vural, Ergin Dileköz, Gökçe Sevim Oztürk, Yusuf Sariogl. Enhancement effects of nicotine on neurogenic contractile responses in rabbit gastric fundus. European journal of pharmacology. vol 561. issue 1-3. 2007-05-22. PMID:17292347. |
in conclusion, nicotine increased efs-evoked contractile responses, possibly by facilitating neurotransmitter release from nerve terminals by a mechanism dependent on the influx of ca(2+) from voltage-gated ca(2+) channels via activation of nicotinic acetylcholine receptors in isolated rabbit gastric fundus. |
2007-05-22 |
2023-08-12 |
rabbit |
| Eun-Joo Shin, Jong Seok Chae, Myung-Eun Jung, Guoying Bing, Kwang Ho Ko, Won-Ki Kim, Myung Bok Wie, Mi-Ae Cheon, Seung-Yeol Nah, Hyoung-Chun Ki. Repeated intracerebroventricular infusion of nicotine prevents kainate-induced neurotoxicity by activating the alpha7 nicotinic acetylcholine receptor. Epilepsy research. vol 73. issue 3. 2007-05-15. PMID:17174071. |
these results suggest that repeated nicotine treatment provides alpha7 nicotinic acetylcholine receptor-mediated neuroprotection against ka toxicity. |
2007-05-15 |
2023-08-12 |
rat |
| Piotr Tutka, Witold Zatońsk. Cytisine for the treatment of nicotine addiction: from a molecule to therapeutic efficacy. Pharmacological reports : PR. vol 58. issue 6. 2007-05-11. PMID:17220536. |
recent pharmacological research has elucidated that the drug is a low efficacy partial agonist of alpha4beta2 nicotinic acetylcholine receptors, which are believed to be central to the effect of nicotine (nic) on the reward pathway. |
2007-05-11 |
2023-08-12 |
Not clear |
| David N Ruskin, Rene Anand, Gerald J LaHost. Menthol and nicotine oppositely modulate body temperature in the rat. European journal of pharmacology. vol 559. issue 2-3. 2007-05-09. PMID:17303112. |
to investigate possible interactions with nicotine, (-)-menthol (200 or 400 mg/kg) and (-)-nicotine (0.5 mg/kg) were injected subcutaneously in rats, and body temperature, which is modulated by brain nicotinic acetylcholine receptors, was measured. |
2007-05-09 |
2023-08-12 |
rat |
| Tiffany J Davis, Christopher M de Fiebr. Alcohol's actions on neuronal nicotinic acetylcholine receptors. Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism. vol 29. issue 3. 2007-05-02. PMID:17373406. |
in the brain, nicotine acts at several different types of receptors collectively known as nicotinic acetylcholine receptors (nachrs). |
2007-05-02 |
2023-08-12 |
Not clear |
| E P Reyes, R Fernández, C Larraín, P Zapat. Effects of combined cholinergic-purinergic block upon cat carotid body chemoreceptors in vitro. Respiratory physiology & neurobiology. vol 156. issue 1. 2007-05-01. PMID:16959549. |
dose-response curves for fchi increases evoked by intra-stream boluses of acetylcholine, nicotine and atp were studied. |
2007-05-01 |
2023-08-12 |
cat |
| Hildegard M Schulle. Neurotransmitter receptor-mediated signaling pathways as modulators of carcinogenesis. Progress in experimental tumor research. vol 39. 2007-04-19. PMID:17314500. |
studies conducted by our laboratory first showed that binding of the parasympathetic neurotransmitter, acetylcholine, as well as nicotine or its nitrosated cancer-causing derivative, nnk, to nicotinic acetylcholine receptors comprised of alpha7 subunits activated a mitogenic signal transduction pathway in normal and neoplastic pulmonary neuroendocrine cells. |
2007-04-19 |
2023-08-12 |
human |
| Luis Ulloa, Ping Wan. The neuronal strategy for inflammation. Novartis Foundation symposium. vol 280. 2007-04-17. PMID:17380797. |
nicotine is more efficient than acetylcholine at inhibiting the nf-kappab pathway and attenuating the production of pro-inflammatory cytokines from macrophages through a mechanism dependent on the alpha7-nicotinic acetylcholine receptor (alpha7n achr). |
2007-04-17 |
2023-08-12 |
Not clear |