| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Ponzoni, M Moretti, M Sala, F Fasoli, V Mucchietto, V Lucini, G Cannazza, G Gallesi, C N Castellana, F Clementi, M Zoli, C Gotti, D Braid. Different physiological and behavioural effects of e-cigarette vapour and cigarette smoke in mice. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 10. 2016-07-12. PMID:26141510. |
chronic intermittent non-contingent, second-hand exposure to cigarette smoke or e-cig vapour led to similar brain cotinine and nicotine levels, similar urine cotinine levels and the similar up-regulation of α4β2 nicotinic acetylcholine receptors in different brain areas, but had different effects on body weight, food intake, and the signs of mecamylamine-precipitated and spontaneous withdrawal episodic memory and emotional responses. |
2016-07-12 |
2023-08-13 |
mouse |
| Shuguang Leng, Joel L Weissfeld, Maria A Picchi, Mindi A Styn, Eric D Claus, Vincent P Clark, Guodong Wu, Cynthia L Thomas, Frank D Gilliland, Jianmin Yuan, Jill M Siegfried, Steven A Belinsk. A prospective and retrospective analysis of smoking behavior changes in ever smokers with high risk for lung cancer from New Mexico and Pennsylvania. International journal of molecular epidemiology and genetics. vol 7. issue 2. 2016-06-23. PMID:27335628. |
the ethnic disparity in adverse smoking behavior between hispanics and non-hispanic whites may be at least partially explained by the sequence variants at 15q25 locus that contains multiple nicotine acetylcholine receptors. |
2016-06-23 |
2023-08-13 |
Not clear |
| Kevin Gibbs, Joseph M Collaco, Sharon A McGrath-Morro. Impact of Tobacco Smoke and Nicotine Exposure on Lung Development. Chest. vol 149. issue 2. 2016-06-21. PMID:26502117. |
this review examines the impact of prenatal tobacco and nicotine exposure on lung development with a particular focus on nicotinic acetylcholine receptors. |
2016-06-21 |
2023-08-13 |
Not clear |
| Carlos A Báez-Pagán, Manuel Delgado-Vélez, José A Lasalde-Dominicc. Activation of the Macrophage α7 Nicotinic Acetylcholine Receptor and Control of Inflammation. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 10. issue 3. 2016-06-20. PMID:25870122. |
activation of the macrophage α7 receptor by acetylcholine, nicotine, or other agonists, selectively inhibits production of pro-inflammatory cytokines while leaving anti-inflammatory cytokines undisturbed. |
2016-06-20 |
2023-08-13 |
human |
| David Chi-Leung Lam, Susan Yang Luo, Kin-Hang Fu, Macy Mei-Sze Lui, Koon-Ho Chan, Ignacio Ivans Wistuba, Boning Gao, Sai-Wah Tsao, Mary Sau-Man Ip, John Dorrance Minn. Nicotinic acetylcholine receptor expression in human airway correlates with lung function. American journal of physiology. Lung cellular and molecular physiology. vol 310. issue 3. 2016-06-15. PMID:26608528. |
nicotine and its derivatives, by binding to nicotinic acetylcholine receptors (nachrs) on bronchial epithelial cells, can regulate cellular signaling and inflammatory processes. |
2016-06-15 |
2023-08-13 |
human |
| Naoya Hirata, Shigeru Yamada, Miki Asanagi, Yuko Sekino, Yasunari Kand. Nicotine induces mitochondrial fission through mitofusin degradation in human multipotent embryonic carcinoma cells. Biochemical and biophysical research communications. vol 470. issue 2. 2016-06-14. PMID:26774337. |
nicotine exerts its cellular functions by acting on nicotinic acetylcholine receptors (nachrs), and adversely affects normal embryonic development. |
2016-06-14 |
2023-08-13 |
human |
| Haiji Sun, Xiaoli M. α5-nAChR modulates nicotine-induced cell migration and invasion in A549 lung cancer cells. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 67. issue 9. 2016-06-13. PMID:26205096. |
by binding to nicotinic acetylcholine receptors (nachrs), nicotine induces the proliferation and migration of non-small cell lung cancer. |
2016-06-13 |
2023-08-13 |
human |
| R J Wickha. How Menthol Alters Tobacco-Smoking Behavior: A Biological Perspective. The Yale journal of biology and medicine. vol 88. issue 3. 2016-06-01. PMID:26339211. |
recent evidence highlights four distinct biological mechanisms that can alter smoking behavior: 1) menthol acts to reduce the initially aversive experiences associated with tobacco smoking; 2) menthol can serve as a highly reinforcing sensory cue when associated with nicotine and promote smoking behavior; 3) menthol's actions on nicotinic acetylcholine receptors may change the reinforcing value of nicotine; and 4) menthol can alter nicotine metabolism, thus increasing nicotine bioavailability. |
2016-06-01 |
2023-08-13 |
Not clear |
| Michael R Post, Walrati Limapichat, Henry A Lester, Dennis A Doughert. Heterologous expression and nonsense suppression provide insights into agonist behavior at α6β2 nicotinic acetylcholine receptors. Neuropharmacology. vol 97. 2016-05-24. PMID:25908401. |
these studies reveal that acetylcholine forms a strong cation-π interaction with the conserved tryptophan, while nicotine and tc299423 do not, suggesting a unique pharmacology for the α6β2 nachr. |
2016-05-24 |
2023-08-13 |
xenopus_laevis |
| Matthias Bauwens, Felix M Mottaghy, Jan Buceriu. PET Imaging of the Human Nicotinic Cholinergic Pathway in Atherosclerosis. Current cardiology reports. vol 17. issue 8. 2016-05-16. PMID:26183620. |
during the past years, non-neuronal vascular nicotinic acetylcholine receptors (nachrs) increasingly have gained interest in cardiovascular research, as they are known to mediate the deleterious effects of nicotine and nitrosamines, components of tobacco smoke, on the vasculature. |
2016-05-16 |
2023-08-13 |
human |
| Rahul Srinivasan, Beverley M Henley, Brandon J Henderson, Tim Indersmitten, Bruce N Cohen, Charlene H Kim, Sheri McKinney, Purnima Deshpande, Cheng Xiao, Henry A Leste. Smoking-Relevant Nicotine Concentration Attenuates the Unfolded Protein Response in Dopaminergic Neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 1. 2016-05-09. PMID:26740650. |
animal model studies suggest nicotine as a neuroprotective agent and nicotinic acetylcholine (ach) receptors (nachrs) as targets for neuroprotection, but the underlying neuroprotective mechanism(s) are unknown. |
2016-05-09 |
2023-08-13 |
mouse |
| Mohammed H Al-Wadei, Jheelam Banerjee, Hussein A N Al-Wadei, Hildegard M Schulle. Nicotine induces self-renewal of pancreatic cancer stem cells via neurotransmitter-driven activation of sonic hedgehog signalling. European journal of cancer (Oxford, England : 1990). vol 52. 2016-05-02. PMID:26689865. |
nicotinic acetylcholine receptors (nachrs) α3, α4, α5 and α7 were expressed and chronic exposure to nicotine increased the protein expression of these receptors. |
2016-05-02 |
2023-08-13 |
Not clear |
| Manale Bensaid, Patrick P Michel, Stewart D Clark, Etienne C Hirsch, Chantal Françoi. Role of pedunculopontine cholinergic neurons in the vulnerability of nigral dopaminergic neurons in Parkinson's disease. Experimental neurology. vol 275 Pt 1. 2016-04-29. PMID:26571193. |
this finding and other studies showing that nicotine, the preferential agonist of nicotinic acetylcholine receptors, is neuroprotective in experimental models of pd suggest that a deficit in ppn excitatory cholinergic inputs might contribute to the death of nigral dopaminergic neurons in pd. |
2016-04-29 |
2023-08-13 |
rat |
| Chun-Chieh Liu, Hung-I Ye. Nicotine: A Double-Edged Sword in Atherosclerotic Disease. Acta Cardiologica Sinica. vol 30. issue 2. 2016-04-28. PMID:27122776. |
with binding to specific nicotinic acetylcholine receptors, nicotine can induce migration and proliferation of vascular cells, and hence enhances angiogenesis. |
2016-04-28 |
2023-08-13 |
Not clear |
| Céline M Bourdin, Jacques Lebreton, Monique Mathé-Allainmat, Steeve H Than. Pharmacological profile of zacopride and new quaternarized fluorobenzamide analogues on mammalian α7 nicotinic acetylcholine receptor. Bioorganic & medicinal chemistry letters. vol 25. issue 16. 2016-04-12. PMID:26087938. |
our results revealed different pharmacological properties between the four compounds on acetylcholine and nicotine currents. |
2016-04-12 |
2023-08-13 |
xenopus_laevis |
| Guillaume Fond, Jean-Arthur Micoulaud-Franchi, Lore Brunel, Alexandra Macgregor, Stéphanie Miot, Régis Lopez, Raphaëlle Richieri, Mocrane Abbar, Christophe Lancon, Dimitris Repanti. Innovative mechanisms of action for pharmaceutical cognitive enhancement: A systematic review. Psychiatry research. vol 229. issue 1-2. 2016-04-05. PMID:26187342. |
methylphenidate, amphetamines, modafinil, nicotine, acetylcholine esterase inhibitors and antidepressants were extensively studied in previous meta-analyses and were not included in the present work. |
2016-04-05 |
2023-08-13 |
human |
| Jérémie Naudé, Malou Dongelmans, Philippe Faur. Nicotinic alteration of decision-making. Neuropharmacology. vol 96. issue Pt B. 2016-03-22. PMID:25498234. |
we focus on the role of nicotine acetylcholine receptors and their different subunits, and on the spatio-temporal dynamics (i.e. |
2016-03-22 |
2023-08-13 |
Not clear |
| Jérémie Naudé, Malou Dongelmans, Philippe Faur. Nicotinic alteration of decision-making. Neuropharmacology. vol 96. issue Pt B. 2016-03-22. PMID:25498234. |
diversity of the neural circuits, short- and long-term effects) of both endogenous acetylcholine and nicotine action. |
2016-03-22 |
2023-08-13 |
Not clear |
| Joseph R Polli, Dorothy L Dobbins, Robert A Kobet, Mary A Farwell, Baohong Zhang, Myon-Hee Lee, Xiaoping Pa. Drug-dependent behaviors and nicotinic acetylcholine receptor expressions in Caenorhabditis elegans following chronic nicotine exposure. Neurotoxicology. vol 47. 2016-03-22. PMID:25530353. |
nicotine, the major psychoactive compound in tobacco, targets nicotinic acetylcholine receptors (nachrs) and results in drug dependence. |
2016-03-22 |
2023-08-13 |
caenorhabditis_elegans |
| Marina R Picciotto, Alan S Lewis, Gerrit I van Schalkwyk, Yann S Mineu. Mood and anxiety regulation by nicotinic acetylcholine receptors: A potential pathway to modulate aggression and related behavioral states. Neuropharmacology. vol 96. issue Pt B. 2016-03-22. PMID:25582289. |
the role of nicotinic acetylcholine receptors (nachrs) in circuits regulating mood and anxiety is beginning to be elucidated in animal models, but the mechanisms underlying the effects of nicotine on aggression-related behavioral states (arbs) are still not understood. |
2016-03-22 |
2023-08-13 |
Not clear |