| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Limor Dinur-Klein, Semion Kertzman, Oded Rosenberg, Moshe Kotler, Abraham Zangen, Pinhas N Danno. Response inhibition and sustained and attention in Heavy smokers versus non-smokers. The Israel journal of psychiatry and related sciences. vol 51. issue 4. 2017-04-04. PMID:25841219. |
repeated nicotine administration induces neuro-adaptations associated with abnormal dopaminergic activity. |
2017-04-04 |
2023-08-13 |
Not clear |
| Sawsan Abuhamdah, Ashraf Khalil, Youssef Sar. Targeting Dopaminergic System for Treating Nicotine Dependence. Central nervous system agents in medicinal chemistry. vol 16. issue 2. 2017-02-23. PMID:26530056. |
targeting dopaminergic system for treating nicotine dependence. |
2017-02-23 |
2023-08-13 |
Not clear |
| Benoit Forget, Mihail Guranda, Islam Gamaleddin, Steven R Goldberg, Bernard Le Fol. Attenuation of cue-induced reinstatement of nicotine seeking by URB597 through cannabinoid CB1 receptor in rats. Psychopharmacology. vol 233. issue 10. 2017-02-22. PMID:26864774. |
faah inhibition has been recently identified as having a critical involvement in behaviors related to nicotine addiction and has been shown to reduce the effect of nicotine on the mesolimbic dopaminergic system via cb1r and peroxisome proliferator-activated receptor alpha (pparα). |
2017-02-22 |
2023-08-13 |
rat |
| Dawei Qi, Qian Zhang, Wanhong Zhou, Jingjing Zhao, Bo Zhang, Yunfei Sha, Zhiqing Pan. Quantification of Dopamine in Brain Microdialysates with High-Performance Liquid Chromatography-Tandem Mass Spectrometry. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. vol 32. issue 4. 2016-12-20. PMID:27063714. |
the dopamine level in the brain and the mesolimbick dopaminergic system are responsible for nicotine addiction. |
2016-12-20 |
2023-08-13 |
rat |
| Andon N Placzek, David L Molfese, Sanjeev Khatiwada, Gonzalo Viana Di Prisco, Wei Huang, Carmela Sidrauski, Krešimir Krnjević, Christopher L Amos, Russell Ray, John A Dani, Peter Walter, Ramiro Salas, Mauro Costa-Mattiol. Translational control of nicotine-evoked synaptic potentiation in mice and neuronal responses in human smokers by eIF2α. eLife. vol 5. 2016-12-13. PMID:26928076. |
here we report that nicotine potentiates excitatory synaptic transmission in ventral tegmental area dopaminergic neurons more readily in adolescent mice compared to adults. |
2016-12-13 |
2023-08-13 |
mouse |
| Juan Camilo Jurado-Coronel, Marco Avila-Rodriguez, Francisco Capani, Janneth Gonzalez, Valentina Echeverria Moran, George E Barret. Targeting the Nicotinic Acetylcholine Receptors (nAChRs) in Astrocytes as a Potential Therapeutic Target in Parkinson's Disease. Current pharmaceutical design. vol 22. issue 10. 2016-12-13. PMID:26972289. |
however, nicotine administration can protect dopaminergic neurons against degeneration by inhibiting astrocytes activation in the substantia nigra pars compacta (snpc) and therefore reduce inflammation. |
2016-12-13 |
2023-08-13 |
Not clear |
| Juçara X Zaparoli, Eduardo K Sugawara, Altay A L de Souza, Sérgio Tufik, José Carlos F Galduró. Omega-3 Levels and Nicotine Dependence: A Cross-Sectional Study and Clinical Trial. European addiction research. vol 22. issue 3. 2016-09-09. PMID:26570994. |
since omega-3 fatty acids play a role in dopaminergic neurotransmission related to dependence, it is important to understand their effects on nicotine dependence. |
2016-09-09 |
2023-08-13 |
Not clear |
| Joshua S Beckmann, Andrew C Meyer, M Pivavarchyk, David B Horton, Guangrong Zheng, Andrew M Smith, Thomas E Wooters, J Michael McIntosh, Peter A Crooks, Michael T Bardo, Linda P Dwoski. r-bPiDI, an α6β2* Nicotinic Receptor Antagonist, Decreases Nicotine-Evoked Dopamine Release and Nicotine Reinforcement. Neurochemical research. vol 40. issue 10. 2016-09-02. PMID:26227997. |
α6β2* nicotinic acetylcholine receptors (nachrs) expressed by dopaminergic neurons mediate nicotine-evoked dopamine (da) release and nicotine reinforcement. |
2016-09-02 |
2023-08-13 |
rat |
| Brandon J Hall, Susan Slade, Cheyenne Allenby, Munir G Kutlu, Edward D Levi. Neuro-anatomic mapping of dopamine D1 receptor involvement in nicotine self-administration in rats. Neuropharmacology. vol 99. 2016-08-30. PMID:25797492. |
dopaminergic signaling has long been known to be a critical factor in nicotine addiction, as well as other drugs of abuse. |
2016-08-30 |
2023-08-13 |
rat |
| Paul T Harrell, Hui-Yi Lin, Jong Y Park, Melissa D Blank, David J Drobes, David E Evan. Dopaminergic genetic variation moderates the effect of nicotine on cigarette reward. Psychopharmacology. vol 233. issue 2. 2016-08-08. PMID:26497691. |
dopaminergic genetic variation moderates the effect of nicotine on cigarette reward. |
2016-08-08 |
2023-08-13 |
Not clear |
| Durna Chalabi-Yani, Hedayat Sahraei, Gholam Hossein Meftahi, Seydeh Bentolhuda Hosseini, Sara Sadeghi-Gharajehdaghi, Hengameh Ali Beig, Zahra Bourbour, Mina Ranjabara. Effect of Transient Inactivation of Ventral Tegmental Area on the Expression and Acquisition of Nicotine-Induced Conditioned Place Preference in Rats. Iranian biomedical journal. vol 19. issue 4. 2016-07-22. PMID:26210948. |
nicotine can activate dopaminergic neurons within the ventral tegmental area (vta). |
2016-07-22 |
2023-08-13 |
rat |
| Matthew W Buczynski, Melissa A Herman, Ku-Lung Hsu, Luis A Natividad, Cristina Irimia, Ilham Y Polis, Holly Pugh, Jae Won Chang, Micah J Niphakis, Benjamin F Cravatt, Marisa Roberto, Loren H Parson. Diacylglycerol lipase disinhibits VTA dopamine neurons during chronic nicotine exposure. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 4. 2016-06-17. PMID:26755579. |
chronic nicotine exposure (cne) alters synaptic transmission in the ventral tegmental area (vta) in a manner that enhances dopaminergic signaling and promotes nicotine use. |
2016-06-17 |
2023-08-13 |
rat |
| Ryan Ting-A-Kee, Andrew Heinmiller, Derek van der Koo. A proposed resolution to the paradox of drug reward: Dopamine's evolution from an aversive signal to a facilitator of drug reward via negative reinforcement. Neuroscience and biobehavioral reviews. vol 56. 2016-06-02. PMID:26116542. |
we suggest that after being consumed, plant neurotoxins such as nicotine activated an aversive dopaminergic pathway, thereby deterring predatory herbivores. |
2016-06-02 |
2023-08-13 |
Not clear |
| Rahul Srinivasan, Beverley M Henley, Brandon J Henderson, Tim Indersmitten, Bruce N Cohen, Charlene H Kim, Sheri McKinney, Purnima Deshpande, Cheng Xiao, Henry A Leste. Smoking-Relevant Nicotine Concentration Attenuates the Unfolded Protein Response in Dopaminergic Neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 1. 2016-05-09. PMID:26740650. |
smoking-relevant nicotine concentration attenuates the unfolded protein response in dopaminergic neurons. |
2016-05-09 |
2023-08-13 |
mouse |
| Manale Bensaid, Patrick P Michel, Stewart D Clark, Etienne C Hirsch, Chantal Françoi. Role of pedunculopontine cholinergic neurons in the vulnerability of nigral dopaminergic neurons in Parkinson's disease. Experimental neurology. vol 275 Pt 1. 2016-04-29. PMID:26571193. |
this finding and other studies showing that nicotine, the preferential agonist of nicotinic acetylcholine receptors, is neuroprotective in experimental models of pd suggest that a deficit in ppn excitatory cholinergic inputs might contribute to the death of nigral dopaminergic neurons in pd. |
2016-04-29 |
2023-08-13 |
rat |
| Thomas P K Breckel, Carsten Giessing, Anja Gieseler, Sarah Querbach, Martin Reuter, Christiane M Thie. Nicotinergic Modulation of Attention-Related Neural Activity Differentiates Polymorphisms of DRD2 and CHRNA4 Receptor Genes. PloS one. vol 10. issue 6. 2016-04-21. PMID:26079805. |
recent findings indicate that genetic variations that affect the cholinergic and dopaminergic neurotransmitter system impact performance in cognitive tasks and effects of nicotine. |
2016-04-21 |
2023-08-13 |
human |
| C R Pinheiro, E G Moura, A C Manhães, M C Fraga, S Claudio-Neto, V Younes-Rapozo, A P Santos-Silva, B M Lotufo, E Oliveira, P C Lisbo. Maternal nicotine exposure during lactation alters food preference, anxiety-like behavior and the brain dopaminergic reward system in the adult rat offspring. Physiology & behavior. vol 149. 2016-04-08. PMID:26048299. |
maternal nicotine exposure during lactation alters food preference, anxiety-like behavior and the brain dopaminergic reward system in the adult rat offspring. |
2016-04-08 |
2023-08-13 |
rat |
| C R Pinheiro, E G Moura, A C Manhães, M C Fraga, S Claudio-Neto, V Younes-Rapozo, A P Santos-Silva, B M Lotufo, E Oliveira, P C Lisbo. Maternal nicotine exposure during lactation alters food preference, anxiety-like behavior and the brain dopaminergic reward system in the adult rat offspring. Physiology & behavior. vol 149. 2016-04-08. PMID:26048299. |
children whose parents smoke are more vulnerable to present addictive-like behavior to drugs and food.we evaluated the association between maternal nicotine exposure during lactation with changes in feeding, behavior and in the dopaminergic reward system. |
2016-04-08 |
2023-08-13 |
rat |
| C R Pinheiro, E G Moura, A C Manhães, M C Fraga, S Claudio-Neto, V Younes-Rapozo, A P Santos-Silva, B M Lotufo, E Oliveira, P C Lisbo. Maternal nicotine exposure during lactation alters food preference, anxiety-like behavior and the brain dopaminergic reward system in the adult rat offspring. Physiology & behavior. vol 149. 2016-04-08. PMID:26048299. |
postnatal exposure to nicotine increases preference for sugar and anxiety levels in the adult progeny possibly due to a decrease in dopaminergic action in the nucleus accumbens and arcuate nucleus. |
2016-04-08 |
2023-08-13 |
rat |
| Minsook Ye, Hyunju Lee, Hyunsu Bae, Dae-Hyun Hahm, Hye-Jung Lee, Insop Shi. Paecilomycies japonica reduces repeated nicotine-induced neuronal and behavioral activation in rats. BMC complementary and alternative medicine. vol 15. 2016-03-09. PMID:26169054. |
many studies have demonstrated that repeated injections of nicotine can produce progressive increases in locomotor activity and enhanced expression of c-fos and tyrosine hydroxylase (th) in brain dopaminergic areas. |
2016-03-09 |
2023-08-13 |
rat |