| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Emily E Roguski, Burt M Sharp, Hao Chen, Shannon G Matt. Full-gestational exposure to nicotine and ethanol augments nicotine self-administration by altering ventral tegmental dopaminergic function due to NMDA receptors in adolescent rats. Journal of neurochemistry. vol 128. issue 5. 2014-04-29. PMID:24147868. |
full-gestational exposure to nicotine and ethanol augments nicotine self-administration by altering ventral tegmental dopaminergic function due to nmda receptors in adolescent rats. |
2014-04-29 |
2023-08-12 |
rat |
| Emily E Roguski, Burt M Sharp, Hao Chen, Shannon G Matt. Full-gestational exposure to nicotine and ethanol augments nicotine self-administration by altering ventral tegmental dopaminergic function due to NMDA receptors in adolescent rats. Journal of neurochemistry. vol 128. issue 5. 2014-04-29. PMID:24147868. |
therefore, we hypothesized that full-gestational exposure to nic + etoh disrupts control of dopaminergic (da) circuitry by ventral tegmental area (vta) nmda receptors, augmenting nicotine sa and da release in nucleus accumbens (nacc) of adolescents. |
2014-04-29 |
2023-08-12 |
rat |
| Emily E Roguski, Burt M Sharp, Hao Chen, Shannon G Matt. Full-gestational exposure to nicotine and ethanol augments nicotine self-administration by altering ventral tegmental dopaminergic function due to NMDA receptors in adolescent rats. Journal of neurochemistry. vol 128. issue 5. 2014-04-29. PMID:24147868. |
we hypothesized that concurrent gestational exposure to nicotine and ethanol would disrupt the control of vta dopaminergic circuitry by nmda receptors. |
2014-04-29 |
2023-08-12 |
rat |
| Babak Bahadori, Natalie D Riediger, Sharla M Farrell, Elisabeth Uitz, Mohammed F Moghadasia. Hypothesis: smoking decreases breast feeding duration by suppressing prolactin secretion. Medical hypotheses. vol 81. issue 4. 2014-04-07. PMID:23948597. |
an analysis of pertinent rodents studies suggests that chronic nicotine administration boosts dopaminergic activity in the tuberoinfundibular tract which functions to inhibit prolactin release; this increase in dopaminergic activity, in turn, may reflect a nicotine-mediated suppression of hypothalamic opioid activity. |
2014-04-07 |
2023-08-12 |
Not clear |
| b' Mikl\\xc3\\xb3s Palotai, Zsolt Bagosi, Mikl\\xc3\\xb3s J\\xc3\\xa1szber\\xc3\\xa9nyi, Krisztina Csabafi, Roberta Dochnal, M\\xc3\\xa1t\\xc3\\xa9 Manczinger, Gyula Telegdy, Gyula Szab\\xc3\\xb. Ghrelin amplifies the nicotine-induced dopamine release in the rat striatum. Neurochemistry international. vol 63. issue 4. 2014-04-02. PMID:23831084.' |
nicotine activates the mesencephalic dopaminergic neurons via nicotinic acetylcholine receptors (nachr). |
2014-04-02 |
2023-08-12 |
rat |
| b' Mikl\\xc3\\xb3s Palotai, Zsolt Bagosi, Mikl\\xc3\\xb3s J\\xc3\\xa1szber\\xc3\\xa9nyi, Krisztina Csabafi, Roberta Dochnal, M\\xc3\\xa1t\\xc3\\xa9 Manczinger, Gyula Telegdy, Gyula Szab\\xc3\\xb. Ghrelin and nicotine stimulate equally the dopamine release in the rat amygdala. Neurochemical research. vol 38. issue 10. 2014-03-28. PMID:23836294.' |
ghrelin and nicotine activates the mesolimbicocortical dopaminergic pathways via growth hormone secretagogue receptors (ghs-r1a) and nicotinic acetylcholine receptors (nachr), respectively, resulting in the release of dopamine in the nucleus accumbens, the amygdala and the prefrontal cortex. |
2014-03-28 |
2023-08-12 |
rat |
| b' Mikl\\xc3\\xb3s Palotai, Zsolt Bagosi, Mikl\\xc3\\xb3s J\\xc3\\xa1szber\\xc3\\xa9nyi, Krisztina Csabafi, Roberta Dochnal, M\\xc3\\xa1t\\xc3\\xa9 Manczinger, Gyula Telegdy, Gyula Szab\\xc3\\xb. Ghrelin and nicotine stimulate equally the dopamine release in the rat amygdala. Neurochemical research. vol 38. issue 10. 2014-03-28. PMID:23836294.' |
the present results demonstrate that both ghrelin and nicotine stimulates directly the dopamine release in the amygdala, an important dopaminergic target area of the mesolimbicocortical pathway. |
2014-03-28 |
2023-08-12 |
rat |
| Susmita Chatterjee, Nathan Santos, Joan Holgate, Carolina L Haass-Koffler, F Woodward Hopf, Viktor Kharazia, Henry Lester, Antonello Bonci, Selena E Bartlet. The α5 subunit regulates the expression and function of α4*-containing neuronal nicotinic acetylcholine receptors in the ventral-tegmental area. PloS one. vol 8. issue 7. 2014-03-05. PMID:23869214. |
while the presence of the α5 subunit blunts the desensitization of nachrs following nicotine exposure, it does not alter the amount of ethanol potentiation of vta dopaminergic neurons. |
2014-03-05 |
2023-08-12 |
mouse |
| Susmita Chatterjee, Nathan Santos, Joan Holgate, Carolina L Haass-Koffler, F Woodward Hopf, Viktor Kharazia, Henry Lester, Antonello Bonci, Selena E Bartlet. The α5 subunit regulates the expression and function of α4*-containing neuronal nicotinic acetylcholine receptors in the ventral-tegmental area. PloS one. vol 8. issue 7. 2014-03-05. PMID:23869214. |
additionally, the α5α4* nachr in vta dopaminergic neurons regulates the effect of nicotine but not ethanol on currents. |
2014-03-05 |
2023-08-12 |
mouse |
| Jaromir Budzianowsk. [Tobacco--once a medicinal plant. Does it contain substances with medicinal properties?]. Przeglad lekarski. vol 70. issue 10. 2014-02-27. PMID:24501813. |
through the effect of this compound on specific nicotinic cholinergic receptors (nachrs), which interacts with nigrostriatal dopaminergic system as well as the possibility of using nicotine for the treatment of parkinson's disease and other neurodegenerative diseases. |
2014-02-27 |
2023-08-12 |
Not clear |
| Xiomara A Perez, J Michael McIntosh, Maryka Qui. Long-term nicotine treatment down-regulates α6β2* nicotinic receptor expression and function in nucleus accumbens. Journal of neurochemistry. vol 127. issue 6. 2014-02-18. PMID:23992036. |
long-term nicotine treatment decreases dopamine (da) transmission in the mesolimbic dopaminergic system. |
2014-02-18 |
2023-08-12 |
rat |
| Beverley M Henley, Brian A Williams, Rahul Srinivasan, Bruce N Cohen, Cheng Xiao, Elisha D W Mackey, Barbara J Wold, Henry A Leste. Transcriptional regulation by nicotine in dopaminergic neurons. Biochemical pharmacology. vol 86. issue 8. 2013-12-17. PMID:23939186. |
transcriptional regulation by nicotine in dopaminergic neurons. |
2013-12-17 |
2023-08-12 |
Not clear |
| Beverley M Henley, Brian A Williams, Rahul Srinivasan, Bruce N Cohen, Cheng Xiao, Elisha D W Mackey, Barbara J Wold, Henry A Leste. Transcriptional regulation by nicotine in dopaminergic neurons. Biochemical pharmacology. vol 86. issue 8. 2013-12-17. PMID:23939186. |
the results give an emerging picture of the role of nicotine on the snc and on dopaminergic neurons. |
2013-12-17 |
2023-08-12 |
Not clear |
| S de la Salle, D Smith, J Choueiry, D Impey, T Philippe, H Dort, A Millar, P Albert, V Knot. Effects of COMT genotype on sensory gating and its modulation by nicotine: Differences in low and high P50 suppressors. Neuroscience. vol 241. 2013-12-12. PMID:23535252. |
elevated smoking rates seen in schizophrenia populations may be an attempt to correct neuropathologies associated with deficient nicotinic acetylcholine receptors and/or dopaminergic systems using exogenous nicotine. |
2013-12-12 |
2023-08-12 |
Not clear |
| Lorinda K Baker, Danyan Mao, Henry Chi, Anitha P Govind, Yolanda F Vallejo, Michael Iacoviello, Stacy Herrera, James J Cortright, William N Green, Daniel S McGehee, Paul Vezin. Intermittent nicotine exposure upregulates nAChRs in VTA dopamine neurons and sensitises locomotor responding to the drug. The European journal of neuroscience. vol 37. issue 6. 2013-08-29. PMID:23331514. |
dopaminergic projections from the ventral tegmental area (vta) to the nucleus accumbens (nacc) mediate the behavioral and motivational effects of many drugs of abuse, including nicotine. |
2013-08-29 |
2023-08-12 |
Not clear |
| Yvonne Paelecke-Habermann, Marko Paelecke, Katharina Giegerich, Katja Reschke, Andrea Küble. Implicit and explicit reward learning in chronic nicotine use. Drug and alcohol dependence. vol 129. issue 1-2. 2013-08-12. PMID:23098679. |
chronic tobacco use is related to specific neurobiological alterations in the dopaminergic brain reward system that can be termed "reward deficiency syndrome" in dependent nicotine consumers. |
2013-08-12 |
2023-08-12 |
Not clear |
| Kanjana Suriyaprom, Rungsunn Tungtrongchitr, Talabporn Harnroongro. Impact of COMT Val 108/158 Met and DRD2 Taq1B gene polymorphisms on vulnerability to cigarette smoking of Thai males. Journal of molecular neuroscience : MN. vol 49. issue 3. 2013-07-25. PMID:22740151. |
the nicotine in cigarette smoke can stimulate the dopaminergic reward pathways. |
2013-07-25 |
2023-08-12 |
Not clear |
| Mariaelvina Sala, Daniela Braida, Luca Pucci, Irene Manfredi, Michael J Marks, Charles R Wageman, Sharon R Grady, Barbara Loi, Sergio Fucile, Francesca Fasoli, Michele Zoli, Bruno Tasso, Fabio Sparatore, Francesco Clementi, Cecilia Gott. CC4, a dimer of cytisine, is a selective partial agonist at α4β2/α6β2 nAChR with improved selectivity for tobacco smoking cessation. British journal of pharmacology. vol 168. issue 4. 2013-07-16. PMID:22957729. |
many of the addictive and rewarding effects of nicotine are due to its actions on the neuronal nicotinic ach receptor (nachr) subtypes expressed in dopaminergic mesocorticolimbic cells. |
2013-07-16 |
2023-08-12 |
Not clear |
| Emma Jane Rose, Thomas J Ross, Betty Jo Salmeron, Mary Lee, Diaa M Shakleya, Marilyn A Huestis, Elliot A Stei. Acute nicotine differentially impacts anticipatory valence- and magnitude-related striatal activity. Biological psychiatry. vol 73. issue 3. 2013-06-28. PMID:22939991. |
dopaminergic activity plays a role in mediating the rewarding aspects of abused drugs, including nicotine. |
2013-06-28 |
2023-08-12 |
Not clear |
| Sulan Luo, Dongting Zhangsun, Yong Wu, Xiaopeng Zhu, Yuanyan Hu, Melissa McIntyre, Sean Christensen, Muharrem Akcan, David J Craik, J Michael McIntos. Characterization of a novel α-conotoxin from conus textile that selectively targets α6/α3β2β3 nicotinic acetylcholine receptors. The Journal of biological chemistry. vol 288. issue 2. 2013-03-26. PMID:23184959. |
α6β2 nicotinic acetylcholine receptors (nachrs) expressed by dopaminergic neurons in the cns are potential therapeutic targets for the treatment of several neuropsychiatric diseases, including nicotine addiction and parkinson disease. |
2013-03-26 |
2023-08-12 |
rat |