| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sybren F de Kloet, Huibert D Mansvelder, Taco J De Vrie. Cholinergic modulation of dopamine pathways through nicotinic acetylcholine receptors. Biochemical pharmacology. vol 97. issue 4. 2016-02-09. PMID:26208783. |
profound modulatory cholinergic input from the pedunculopontine and laterodorsal tegmentum to dopaminergic midbrain nuclei as well as local cholinergic interneuron projections to dopamine neuron axons in the striatum may play a major role in the effects of nicotine. |
2016-02-09 |
2023-08-13 |
Not clear |
| Paula L Vieira-Brock, Lisa M McFadden, Shannon M Nielsen, Jonathan D Ellis, Elliot T Walters, Kristen A Stout, J Michael McIntosh, Diana G Wilkins, Glen R Hanson, Annette E Fleckenstei. Chronic Nicotine Exposure Attenuates Methamphetamine-Induced Dopaminergic Deficits. The Journal of pharmacology and experimental therapeutics. vol 355. issue 3. 2016-02-09. PMID:26391161. |
chronic nicotine exposure attenuates methamphetamine-induced dopaminergic deficits. |
2016-02-09 |
2023-08-13 |
Not clear |
| Paula L Vieira-Brock, Lisa M McFadden, Shannon M Nielsen, Jonathan D Ellis, Elliot T Walters, Kristen A Stout, J Michael McIntosh, Diana G Wilkins, Glen R Hanson, Annette E Fleckenstei. Chronic Nicotine Exposure Attenuates Methamphetamine-Induced Dopaminergic Deficits. The Journal of pharmacology and experimental therapeutics. vol 355. issue 3. 2016-02-09. PMID:26391161. |
many meth abusers smoke cigarettes and thus self-administer nicotine; yet few studies have investigated the effects of nicotine on meth-induced dopaminergic deficits. |
2016-02-09 |
2023-08-13 |
Not clear |
| Paula L Vieira-Brock, Lisa M McFadden, Shannon M Nielsen, Jonathan D Ellis, Elliot T Walters, Kristen A Stout, J Michael McIntosh, Diana G Wilkins, Glen R Hanson, Annette E Fleckenstei. Chronic Nicotine Exposure Attenuates Methamphetamine-Induced Dopaminergic Deficits. The Journal of pharmacology and experimental therapeutics. vol 355. issue 3. 2016-02-09. PMID:26391161. |
this study revealed that oral nicotine exposure beginning in adolescence [postnatal day (pnd) 40] through adulthood [pnd 96] attenuated meth-induced striatal dopaminergic deficits when meth was administered at pnd 89. |
2016-02-09 |
2023-08-13 |
Not clear |
| Paula L Vieira-Brock, Lisa M McFadden, Shannon M Nielsen, Jonathan D Ellis, Elliot T Walters, Kristen A Stout, J Michael McIntosh, Diana G Wilkins, Glen R Hanson, Annette E Fleckenstei. Chronic Nicotine Exposure Attenuates Methamphetamine-Induced Dopaminergic Deficits. The Journal of pharmacology and experimental therapeutics. vol 355. issue 3. 2016-02-09. PMID:26391161. |
these findings indicate that nicotine protects against meth-induced striatal dopaminergic deficits, perhaps by affecting α4β2 and/or α6β2 expression, and that both age of onset and duration of nicotine exposure affect this protection. |
2016-02-09 |
2023-08-13 |
Not clear |
| Manivannan Subramaniyan, John A Dan. Dopaminergic and cholinergic learning mechanisms in nicotine addiction. Annals of the New York Academy of Sciences. vol 1349. 2015-12-07. PMID:26301866. |
dopaminergic and cholinergic learning mechanisms in nicotine addiction. |
2015-12-07 |
2023-08-13 |
Not clear |
| Manivannan Subramaniyan, John A Dan. Dopaminergic and cholinergic learning mechanisms in nicotine addiction. Annals of the New York Academy of Sciences. vol 1349. 2015-12-07. PMID:26301866. |
here, we focus on the acquisition phase of smoking addiction and review animal model studies on how nicotine modifies dopaminergic and cholinergic signaling in key nodes of the reinforcement circuitry: ventral tegmental area, nucleus accumbens (nac), amygdala, and hippocampus. |
2015-12-07 |
2023-08-13 |
Not clear |
| Li Wang, Shujiang Shang, Xinjiang Kang, Sasa Teng, Feipeng Zhu, Bin Liu, Qihui Wu, Mingli Li, Wei Liu, Huadong Xu, Li Zhou, Ruiying Jiao, Haiqiang Dou, Panli Zuo, Xiaoyu Zhang, Lianghong Zheng, Shirong Wang, Changhe Wang, Zhuan Zho. Modulation of dopamine release in the striatum by physiologically relevant levels of nicotine. Nature communications. vol 5. 2015-12-03. PMID:24968237. |
nicotine does not affect the ap(da)-dependent da release (ap(da), ap of dopaminergic axon). |
2015-12-03 |
2023-08-13 |
Not clear |
| Raphaël Eddine, Sebastien Valverde, Stefania Tolu, Daniel Dautan, Audrey Hay, Carole Morel, Yihui Cui, Bertrand Lambolez, Laurent Venance, Fabio Marti, Philippe Faur. A concurrent excitation and inhibition of dopaminergic subpopulations in response to nicotine. Scientific reports. vol 5. 2015-12-01. PMID:25640814. |
a concurrent excitation and inhibition of dopaminergic subpopulations in response to nicotine. |
2015-12-01 |
2023-08-13 |
Not clear |
| Michio Itasaka, Naoyuki Hironaka, Hisatsugu Miyat. [Behavioral characteristics of nicotine seeking: a role of the nicotine-conditioned effects and other mechanisms]. Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence. vol 50. issue 3. 2015-11-30. PMID:26502572. |
after having the repeated pavlovian conditioning in the training/conditioning sessions, css begin to play a key role for eliciting nicotine seeking behavior, with the activation of mesolimbic dopaminergic systems. |
2015-11-30 |
2023-08-13 |
human |
| Matthew I Palmatier, Marissa R Kellicut, A Brianna Sheppard, Russell W Brown, Donita L Robinso. The incentive amplifying effects of nicotine are reduced by selective and non-selective dopamine antagonists in rats. Pharmacology, biochemistry, and behavior. vol 126. 2015-11-09. PMID:25230311. |
these experiments are the first to investigate the effects of dopaminergic drugs on the facilitation of sign-tracking engendered by nicotine and they implicate dopaminergic systems both in conditioned approach as well as the incentive-promoting effects of nicotine. |
2015-11-09 |
2023-08-13 |
rat |
| Yuan Liu, Xiaoning Zeng, Yujian Hui, Chenlei Zhu, Jie Wu, Devin H Taylor, Juan Ji, Weimin Fan, Zuhu Huang, Jun H. Activation of α7 nicotinic acetylcholine receptors protects astrocytes against oxidative stress-induced apoptosis: implications for Parkinson's disease. Neuropharmacology. vol 91. 2015-09-28. PMID:25486621. |
systemic administration of nicotine dramatically alleviated mptp-induced symptoms, protected dopaminergic neurons against degeneration, inhibited astrocytes and microglia activation in the substantia nigra pars compacta (snpc) and blocked the decrease of gdnf in the striatum by activating α7-nachrs. |
2015-09-28 |
2023-08-13 |
Not clear |
| Frédéric Chagué, Charles Guenancia, Aurélie Gudjoncik, Daniel Moreau, Yves Cottin, Marianne Zelle. Smokeless tobacco, sport and the heart. Archives of cardiovascular diseases. vol 108. issue 1. 2015-09-16. PMID:25497687. |
importantly, smokeless tobacco, similar to cigarette smoking, leads to nicotine dependence through dopaminergic pathways. |
2015-09-16 |
2023-08-13 |
Not clear |
| Tanuja Bordia, J Michael McIntosh, Maryka Qui. The nicotine-mediated decline in l-dopa-induced dyskinesias is associated with a decrease in striatal dopamine release. Journal of neurochemistry. vol 125. issue 2. 2015-08-18. PMID:23373725. |
this study investigates whether nicotine may exert its beneficial effects by modulating pre-synaptic dopaminergic function. |
2015-08-18 |
2023-08-12 |
rat |
| Tanuja Bordia, J Michael McIntosh, Maryka Qui. The nicotine-mediated decline in l-dopa-induced dyskinesias is associated with a decrease in striatal dopamine release. Journal of neurochemistry. vol 125. issue 2. 2015-08-18. PMID:23373725. |
these data suggest that nicotine may improve lids in parkinsonian animal models by dampening striatal dopaminergic activity. |
2015-08-18 |
2023-08-12 |
rat |
| Manindra Nath Tiwari, Swati Agarwal, Priyanka Bhatnagar, Naveen Kumar Singhal, Shashi Kant Tiwari, Pradeep Kumar, Lalit Kumar Singh Chauhan, Devendra Kumar Patel, Rajnish Kumar Chaturvedi, Mahendra Pratap Singh, Kailash Chand Gupt. Nicotine-encapsulated poly(lactic-co-glycolic) acid nanoparticles improve neuroprotective efficacy against MPTP-induced parkinsonism. Free radical biology & medicine. vol 65. 2015-08-07. PMID:23933227. |
the selected indicators of oxidative stress, dopaminergic neurodegeneration and apoptosis, were measured in both in vitro and rodent models of parkinsonism in the presence or absence of "nanotized" or bulk nicotine. |
2015-08-07 |
2023-08-12 |
mouse |
| Elizabeth Glenn Guy, Paul J Fletche. Responding for a conditioned reinforcer, and its enhancement by nicotine, is blocked by dopamine receptor antagonists and a 5-HT(2C) receptor agonist but not by a 5-HT(2A) receptor antagonist. Pharmacology, biochemistry, and behavior. vol 125. 2015-07-28. PMID:25158104. |
this effect of nicotine to enhance responding for a conditioned reinforcer is likely due to nicotine-induced enhancements in mesolimbic dopaminergic activity, but this has not been directly assessed. |
2015-07-28 |
2023-08-13 |
rat |
| Laura E O'Dell, Luis A Natividad, Joseph A Pipkin, Francisco Roman, Ivan Torres, Jesus Jurado, Oscar V Torres, Theodore C Friedman, John M Tenayuca, Arbi Nazaria. Enhanced nicotine self-administration and suppressed dopaminergic systems in a rat model of diabetes. Addiction biology. vol 19. issue 6. 2015-07-20. PMID:23834715. |
enhanced nicotine self-administration and suppressed dopaminergic systems in a rat model of diabetes. |
2015-07-20 |
2023-08-12 |
rat |
| Francesco Pistillo, Francesco Clementi, Michele Zoli, Cecilia Gott. Nicotinic, glutamatergic and dopaminergic synaptic transmission and plasticity in the mesocorticolimbic system: focus on nicotine effects. Progress in neurobiology. vol 124. 2015-07-09. PMID:25447802. |
nicotinic, glutamatergic and dopaminergic synaptic transmission and plasticity in the mesocorticolimbic system: focus on nicotine effects. |
2015-07-09 |
2023-08-13 |
mouse |
| Francesco Pistillo, Francesco Clementi, Michele Zoli, Cecilia Gott. Nicotinic, glutamatergic and dopaminergic synaptic transmission and plasticity in the mesocorticolimbic system: focus on nicotine effects. Progress in neurobiology. vol 124. 2015-07-09. PMID:25447802. |
it is now becoming clear that various aspects of nicotine dependence are mediated by close interactions of the glutamatergic, dopaminergic and γ-aminobutyric acidergic systems in the mesocorticolimbic system. |
2015-07-09 |
2023-08-13 |
mouse |