| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mehmet Atilla Uysal, Ülgen Sever, Ayşe Feyda Nursal, Sacide Pehlİva. Dopamine D4 Receptor Gene Exon III VNTR Variant Influences Smoking Status in Turkish Population. Noro psikiyatri arsivi. vol 56. issue 4. 2020-10-01. PMID:31903031. |
dopaminergic gene variants may affect nicotine dependence through their possible impact on the dopamine reward pathway. |
2020-10-01 |
2023-08-13 |
Not clear |
| Josephine R Tarren, Henry A Lester, Arnauld Belmer, Selena E Bartlet. Acute Ethanol Administration Upregulates Synaptic α4-Subunit of Neuronal Nicotinic Acetylcholine Receptors within the Nucleus Accumbens and Amygdala. Frontiers in molecular neuroscience. vol 10. 2020-09-30. PMID:29114204. |
effects of ethanol on specific brain nachr subtypes within the mesolimbic dopaminergic (da) pathway may be a key element in the comorbidity of ethanol and nicotine. |
2020-09-30 |
2023-08-13 |
mouse |
| In Soo Ryu, Jieun Kim, Su Yeon Seo, Ju Hwan Yang, Jeong Hwan Oh, Dong Kun Lee, Hyun-Wook Cho, Kyuhong Lee, Seong Shoon Yoon, Joung-Wook Seo, Insop Shim, Eun Sang Cho. Repeated Administration of Cigarette Smoke Condensate Increases Glutamate Levels and Behavioral Sensitization. Frontiers in behavioral neuroscience. vol 12. 2020-09-30. PMID:29615877. |
nicotine, a nicotinic acetylcholine receptor agonist, produces the reinforcing effects of tobacco dependence by potentiating dopaminergic and glutamatergic neurotransmission. |
2020-09-30 |
2023-08-13 |
rat |
| Terril L Verplaetse, Evan D Morris, Sherry A McKee, Kelly P Cosgrov. Sex differences in the nicotinic acetylcholine and dopamine receptor systems underlying tobacco smoking addiction. Current opinion in behavioral sciences. vol 23. 2020-09-30. PMID:31341936. |
we review the recent imaging literature on sex differences in the nicotinic acetylcholine receptor system and in the dopaminergic system in response to nicotine administration and tobacco smoking. |
2020-09-30 |
2023-08-13 |
Not clear |
| Gloria Pérez-Rubio, Salvador García-Carmona, Leonor García-Gómez, Andrea Hernández-Pérez, Alejandra Ramírez-Venegas, Luis Alberto López-Flores, Raúl Sansores, Ramcés Falfán-Valenci. The VNTR 48 bp Polymorphism in the Diagnostics (Basel, Switzerland). vol 10. issue 1. 2020-09-28. PMID:31905892. |
the vntr 48 bp polymorphism in the cigarette smoking is influenced by nicotine's effects on dopaminergic activity, which appear to be moderated by genetic variation, particularly a variable number tandem repeat (vntr, 48 bp) polymorphism in the third exon of the dopamine receptor gene ( |
2020-09-28 |
2023-08-13 |
Not clear |
| Raj Kumar Tiwari, Vikas Sharma, Ravindra Kumar Pandey, Shiv Shankar Shukl. Nicotine Addiction: Neurobiology and Mechanism. Journal of pharmacopuncture. vol 23. issue 1. 2020-09-28. PMID:32322429. |
further, the neurobiological pathway to nicotine dependence might perhaps be appropriate to the attachment of nicotine to nicotinic acetylcholine receptors, peruse by stimulation of dopaminergic system and activation of general pharmacological changes that might be responsible for nicotine addiction. |
2020-09-28 |
2023-08-13 |
Not clear |
| Robert A Waeiss, Christopher P Knight, Gustavo B Carvajal, Richard L Bell, Eric A Engleman, William J McBride, Sheketha R Hauser, Zachary A Rod. Peri-adolescent alcohol consumption increases sensitivity and dopaminergic response to nicotine during adulthood in female alcohol-preferring (P) rats: Alterations to α7 nicotinic acetylcholine receptor expression. Behavioural brain research. vol 376. 2020-09-17. PMID:31473285. |
peri-adolescent alcohol consumption increases sensitivity and dopaminergic response to nicotine during adulthood in female alcohol-preferring (p) rats: alterations to α7 nicotinic acetylcholine receptor expression. |
2020-09-17 |
2023-08-13 |
human |
| Zeyi Huang, Daichao Wu, Xilin Qu, Meixiang Li, Ju Zou, Sijie Ta. BDNF and nicotine dependence: associations and potential mechanisms. Reviews in the neurosciences. 2020-09-05. PMID:32887210. |
although it is well known that nicotine binds to the nicotinic acetylcholine receptors (nachrs) and activates the mesolimbic dopaminergic system (mds) to generate the pleasant and rewarding effects, the molecular mechanisms of nicotine addiction are not fully understood. |
2020-09-05 |
2023-08-13 |
Not clear |
| Karin Sandager-Nielsen, Philip K Ahring, Jessica Klein, Marloes van Hout, Siganya Thaneshwaran, Altair B Dos Santos, Thomas A Jacobsen, Dipak V Amrutkar, Dan Peters, Anders A Jensen, Kristi A Kohlmeier, Palle Christophersen, Tino Dyhrin. Characterization of AN317, a novel selective agonist of α6β2-containing nicotinic acetylcholine receptors. Biochemical pharmacology. vol 174. 2020-08-24. PMID:31887288. |
α6β2-containing (α6β2*) nachrs are highly expressed in and regulate the activity of midbrain dopaminergic neurons, which makes them attractive drug targets in several psychiatric and neurological diseases, including nicotine addiction and parkinson's disease. |
2020-08-24 |
2023-08-13 |
Not clear |
| Benedetto Romoli, Adrian F Lozada, Ivette M Sandoval, Fredric P Manfredsson, Thomas S Hnasko, Darwin K Berg, Davide Dulci. Neonatal Nicotine Exposure Primes Midbrain Neurons to a Dopaminergic Phenotype and Increases Adult Drug Consumption. Biological psychiatry. vol 86. issue 5. 2020-08-13. PMID:31202491. |
neonatal nicotine exposure primes midbrain neurons to a dopaminergic phenotype and increases adult drug consumption. |
2020-08-13 |
2023-08-13 |
Not clear |
| Benedetto Romoli, Adrian F Lozada, Ivette M Sandoval, Fredric P Manfredsson, Thomas S Hnasko, Darwin K Berg, Davide Dulci. Neonatal Nicotine Exposure Primes Midbrain Neurons to a Dopaminergic Phenotype and Increases Adult Drug Consumption. Biological psychiatry. vol 86. issue 5. 2020-08-13. PMID:31202491. |
nicotine intake induces addiction through neuroplasticity of the reward circuitry, altering the activity of dopaminergic neurons of the ventral tegmental area. |
2020-08-13 |
2023-08-13 |
Not clear |
| Benedetto Romoli, Adrian F Lozada, Ivette M Sandoval, Fredric P Manfredsson, Thomas S Hnasko, Darwin K Berg, Davide Dulci. Neonatal Nicotine Exposure Primes Midbrain Neurons to a Dopaminergic Phenotype and Increases Adult Drug Consumption. Biological psychiatry. vol 86. issue 5. 2020-08-13. PMID:31202491. |
here we investigated the effects of neonatal nicotine exposure on the dopaminergic system and nicotine consumption in adulthood. |
2020-08-13 |
2023-08-13 |
Not clear |
| Carole Morel, Sarah Montgomery, Ming-Hu Ha. Nicotine and alcohol: the role of midbrain dopaminergic neurons in drug reinforcement. The European journal of neuroscience. vol 50. issue 3. 2020-08-07. PMID:30251377. |
nicotine and alcohol: the role of midbrain dopaminergic neurons in drug reinforcement. |
2020-08-07 |
2023-08-13 |
Not clear |
| Carole Morel, Sarah Montgomery, Ming-Hu Ha. Nicotine and alcohol: the role of midbrain dopaminergic neurons in drug reinforcement. The European journal of neuroscience. vol 50. issue 3. 2020-08-07. PMID:30251377. |
additionally, this review briefly summarizes the role of vta da neurons in nicotine, alcohol, and their synergistic effects in reinforcement and also addresses the remaining questions related to the circuit-function specificity of the dopaminergic system in mediating nicotine/alcohol reinforcement and comorbidity. |
2020-08-07 |
2023-08-13 |
Not clear |
| Renee F Keller, Tina Kazemi, Andrei Dragomir, Yasemin M Akay, Metin Aka. Comparison between dopaminergic and non-dopaminergic neurons in the VTA following chronic nicotine exposure during pregnancy. Scientific reports. vol 9. issue 1. 2020-07-27. PMID:30679632. |
comparison between dopaminergic and non-dopaminergic neurons in the vta following chronic nicotine exposure during pregnancy. |
2020-07-27 |
2023-08-13 |
rat |
| Renee F Keller, Tina Kazemi, Andrei Dragomir, Yasemin M Akay, Metin Aka. Comparison between dopaminergic and non-dopaminergic neurons in the VTA following chronic nicotine exposure during pregnancy. Scientific reports. vol 9. issue 1. 2020-07-27. PMID:30679632. |
several studies have shown that nicotine produces long-lasting effects on gene expression within many brain regions, including the ventral tegmental area (vta), which is the origin of dopaminergic neurons and the dopamine reward pathway. |
2020-07-27 |
2023-08-13 |
rat |
| Renee F Keller, Tina Kazemi, Andrei Dragomir, Yasemin M Akay, Metin Aka. Comparison between dopaminergic and non-dopaminergic neurons in the VTA following chronic nicotine exposure during pregnancy. Scientific reports. vol 9. issue 1. 2020-07-27. PMID:30679632. |
using a well-established rat model for perinatal nicotine exposure, we sought to investigate altered biological pathways using mrna and mirna expression profiles of dopaminergic (da) and non-dopaminergic (non-da) neurons in this highly-valuable area. |
2020-07-27 |
2023-08-13 |
rat |
| Amol V Shivange, Philip M Borden, Anand K Muthusamy, Aaron L Nichols, Kallol Bera, Huan Bao, Ishak Bishara, Janice Jeon, Matthew J Mulcahy, Bruce Cohen, Saidhbhe L O'Riordan, Charlene Kim, Dennis A Dougherty, Edwin R Chapman, Jonathan S Marvin, Loren L Looger, Henry A Leste. Determining the pharmacokinetics of nicotinic drugs in the endoplasmic reticulum using biosensors. The Journal of general physiology. vol 151. issue 6. 2020-06-24. PMID:30718376. |
we target inicsnfr3 biosensors either to the plasma membrane or to the er and measure nicotine kinetics in hela, sh-sy5y, n2a, and hek293 cell lines, as well as mouse hippocampal neurons and human stem cell-derived dopaminergic neurons. |
2020-06-24 |
2023-08-13 |
mouse |
| Louise Adermark, Julia Morud, Amir Lotfi, Mia Ericson, Bo Söderpal. Acute and chronic modulation of striatal endocannabinoid-mediated plasticity by nicotine. Addiction biology. vol 24. issue 3. 2020-05-18. PMID:29292565. |
nicotine may thus modulate ecb-signaling by affecting dopaminergic and cholinergic neurotransmission in a long-lasting manner. |
2020-05-18 |
2023-08-13 |
Not clear |
| Jing Yang, Dong-Jun Lv, Ling-Xi Li, Ya-Li Wang, Di Qi, Jing Chen, Cheng-Jie Mao, Fen Wang, Yi Liu, Li-Fang Hu, Chun-Feng Li. Nicotine improved the olfactory impairment in MPTP-induced mouse model of Parkinson's disease. Neurotoxicology. vol 73. 2020-04-27. PMID:30978411. |
in addition, nicotine ameliorated the loss of cholinergic neurons and dopaminergic innervation in the horizontal limb of the diagonal band (hdb), which is the primary origin of cholinergic input to the ob. |
2020-04-27 |
2023-08-13 |
mouse |