| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L György, M Dód. Influence of apomorphine on sympathetic neural transmission in the nictitating membrane of the cat. Archives internationales de pharmacodynamie et de therapie. vol 226. issue 2. 1977-08-12. PMID:195545. |
haloperidol antagonized the inhibition evoked by dopamine but did not influence the similar effect of noradrenaline. |
1977-08-12 |
2023-08-11 |
cat |
| G Gianutsos, K E Moor. Increase in mouse brain dopamine content by baclofen: effects of apomorphine and neuroleptics. Psychopharmacology. vol 52. issue 3. 1977-08-12. PMID:406622. |
haloperidol but not pimozide counteracts this effect of apomorphine and dose-dependently enhances the increase in brain dopamine produced by baclofen. |
1977-08-12 |
2023-08-11 |
mouse |
| M Massott. Involvement of striatal dopamine, homovanillic acid and 3,4-dihydroxyphenylacetic acid in the hypothermia and catalepsy induced by haloperidol. Pharmacological research communications. vol 9. issue 4. 1977-07-29. PMID:559310. |
involvement of striatal dopamine, homovanillic acid and 3,4-dihydroxyphenylacetic acid in the hypothermia and catalepsy induced by haloperidol. |
1977-07-29 |
2023-08-11 |
Not clear |
| W Janiec, T Piekarska, M Szczypior, E Misterkiewic. The effect of apomorphine, amantadine and dimethylaminoadamantane on the level of cyclic AMP in the rat striatum. Polish journal of pharmacology and pharmacy. vol 29. issue 2. 1977-06-30. PMID:193093. |
the content of cyclic amp (camp) in the slices of rat striatum and cerebral cortex was tested after incubation with various concentrations (10(-6)--10(4) m) of dopamine (da), apomorphine (apm), amantadine (amd), and dimethylaminoadamatane (dmad), and incubation with da, amd and dmad in combination with kcl (43 mm) or haloperidol (hp) (10(-5) m). |
1977-06-30 |
2023-08-11 |
rat |
| W Kehr, A Carlsson, M Lindqvis. Catecholamine synthesis in rat brain after axotomy: interaction between apomorphine and haloperidol. Naunyn-Schmiedeberg's archives of pharmacology. vol 297. issue 2. 1977-06-22. PMID:193050. |
in c. striatum and the limbic system haloperidol caused a decrease in dopamine on the intact side which was not antagonized by additional treatment with apomorphine. |
1977-06-22 |
2023-08-11 |
rat |
| A Carlsson, W Kehr, M Lindqvis. Agonist--antagonist interaction on dopamine receptors in brain, as reflected in the rates of tyrosine and tryptophan hydroxylation. Journal of neural transmission. vol 40. issue 2. 1977-06-22. PMID:323424. |
the threshold dose was severalfold higher in the noradrenaline-predominated hemisphere portion than in the dopamine-rich striatal and limbic regions, suggesting a higher affinity of haloperidol for dopamine than for noradrenaline receptors. |
1977-06-22 |
2023-08-11 |
rat |
| C J Pycock, P G Jenner, C D Marsde. The interaction of clonidine with dopamine-dependent behaviour in rodents. Naunyn-Schmiedeberg's archives of pharmacology. vol 297. issue 2. 1977-06-22. PMID:558529. |
clonidine (0.5 mg/kg) potentiated the cataleptic effect of the dopamine antagonist haloperidol (0.1-2 mg/kg) in rats. |
1977-06-22 |
2023-08-11 |
mouse |
| S A Darwish, B L Furma. Effects of levodopa and dopamine of plasma glucose concentration in mice. European journal of pharmacology. vol 41. issue 4. 1977-05-20. PMID:139316. |
the hypoglycaemic response to levodopa was prevented by the dopamine antagonists, haloperidol and pimozide. |
1977-05-20 |
2023-08-11 |
mouse |
| M J Bastie, N Vaysse, B Brenac, J P Pascal, A Ribe. Effects of catecholamines and their inhibitors on the isolated canine pancreas. II. Dopamine. Gastroenterology. vol 72. issue 4 Pt 1. 1977-04-28. PMID:838228. |
dopaminergic agonists (dopamine, 2, 10, 50, and 250 mug; apomorphine, 1 mg; noradrenaline, 2, 20, and 200 mug), and inhibitors (haloperidol, 5 mg; pentamethonium, 500 mg; phenoxybenzamine, 15 mg, and atropine sulfate, 10 mg), were tested on isolated perfused canine pancreas; under basal conditions and under stimulation by a background of secretin (0.1, 0.5, and 10.0 clinical unit per hr), or of caerulein (1200 ng per hr). |
1977-04-28 |
2023-08-11 |
Not clear |
| M J Bastie, N Vaysse, B Brenac, J P Pascal, A Ribe. Effects of catecholamines and their inhibitors on the isolated canine pancreas. II. Dopamine. Gastroenterology. vol 72. issue 4 Pt 1. 1977-04-28. PMID:838228. |
low doses of dopamine induced a vasodilation inhibited by haloperidol large doses induced a vasoconstriction, presumably by stimulation of alpha adrenergic receptors. |
1977-04-28 |
2023-08-11 |
Not clear |
| M J Bastie, N Vaysse, B Brenac, J P Pascal, A Ribe. Effects of catecholamines and their inhibitors on the isolated canine pancreas. II. Dopamine. Gastroenterology. vol 72. issue 4 Pt 1. 1977-04-28. PMID:838228. |
secretory response to noradrenaline after phenoxy benzamine was inhibited by haloperidol, suggesting that this effect was mediated by the stimulation of dopamine receptors of the cells. |
1977-04-28 |
2023-08-11 |
Not clear |
| M Laubie, H Schmitt, M Drouilla. Central sites and mechanisms of the hypotensive and bradycardic effects of the narcotic analgesic agent fentanyl. Naunyn-Schmiedeberg's archives of pharmacology. vol 296. issue 3. 1977-04-25. PMID:14307. |
blockade of dopamine receptors by haloperidol or pimozide or of serotonin receptors by methysergide did not change the hypotensive, bradycardic and sympathoinhibitory effects of fentanyl. |
1977-04-25 |
2023-08-11 |
Not clear |
| J Bockaert, J P Tassin, A M Thierry, J Glowinski, J Premon. Characteristics of dopamine and beta-adrenergic sensitive adenylate cyclases in the frontal cerebral cortex of the rat. Comparative effects of neuroleptics on frontal cortex and striatal dopamine sensitive adenylate cyclases. Brain research. vol 122. issue 1. 1977-04-15. PMID:837225. |
thus, haloperidol was less effective than fluphenazine in blocking the striatal dopaminergic receptors, and equally potent than fluphenazine in inhibiting the frontal cerebral cortex dopamine sensitive adenylate cyclase. |
1977-04-15 |
2023-08-11 |
rat |
| K M Braunstein, K E Sarji, J Kleinfelder, H B Schraibman, J A Colwell, K Eureniu. The effects of dopamine on human platelet aggregation, in vitro. The Journal of pharmacology and experimental therapeutics. vol 200. issue 2. 1977-04-15. PMID:839449. |
phentolamine is able to block dopamine enhancement of adp aggregation, but propranolol and haloperidol fail to prevent dopamine inhibition of epinephrine aggregation. |
1977-04-15 |
2023-08-11 |
human |
| P Protais, J Costentin, J C Schwart. Climbing behavior induced by apomorphine in mice: a simple test for the study of dopamine receptors in striatum. Psychopharmacology. vol 50. issue 1. 1977-03-31. PMID:827755. |
this peculiar behavior appears to be elicited by stimulation of dopamine receptors in the striatum: it is suppressed after coagulation of this structure while it is facilitated when these receptors are made hypersensitive by previous treatments with 6-hydroxy-dopamine or haloperidol; on the other hand, it is not modified by coagulation of the nucleus accumbens. |
1977-03-31 |
2023-08-11 |
mouse |
| P Laduron, K de Bie, J Leyse. Specific effect of haloperidol on dopamine turnover in the frontal cortex. Naunyn-Schmiedeberg's archives of pharmacology. vol 296. issue 2. 1977-03-31. PMID:834317. |
specific effect of haloperidol on dopamine turnover in the frontal cortex. |
1977-03-31 |
2023-08-11 |
rabbit |
| E Laschka, A Herz, J Bläsi. Activity of the nigro-striatal dopaminergic system during precipitated morphine withdrawal investigated in rats with acute unilateral inactivation of the striatum. Naunyn-Schmiedeberg's archives of pharmacology. vol 296. issue 1. 1977-03-21. PMID:1034882. |
this contralateral circling was only slightly enhanced by haloperidol, but strongly enhanced by a low dosage of apomorphine as well as by some weak dopamine agonists such as cb 154 or by 101. |
1977-03-21 |
2023-08-11 |
rat |
| A K Mukhopadhyay, N Weisbrod. Effect of dopamine on esophageal motor function. The American journal of physiology. vol 232. issue 1. 1977-03-15. PMID:835699. |
both haloperidol and bulbocapnine potently antagonized the effect of dopamine. |
1977-03-15 |
2023-08-11 |
Not clear |
| G Gianutsos, J E Thornburg, K E Moor. Differential actions of dopamine agonists and antagonists on the gamma-butyrolactone-induced in mouse brain dopamine. Psychopharmacology. vol 50. issue 3. 1977-02-26. PMID:826966. |
after chronic treatment with haloperidol or pimozide, there was no alteration of the maximum gbl-induced increase in dopamine nor was there any significant change in the antagonism by apomorphine, although a trend toward increased sensitivity to apomorphine was noted in the group withdrawn from haloperidol. |
1977-02-26 |
2023-08-11 |
mouse |
| G Gianutsos, J E Thornburg, K E Moor. Differential actions of dopamine agonists and antagonists on the gamma-butyrolactone-induced in mouse brain dopamine. Psychopharmacology. vol 50. issue 3. 1977-02-26. PMID:826966. |
these results suggest that in the mouse, haloperidol is a more effective antagonist of presynaptic dopamine autoreceptors than pimozide, while apomorphine is a better presynaptic agonist than piribedil. |
1977-02-26 |
2023-08-11 |
mouse |