| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J De Belleroche, H F Bradfor. Biochemical evidence for the presence of presynaptic receptors on dopaminergic nerve terminals. Brain research. vol 142. issue 1. 1978-04-26. PMID:626919. |
haloperidol (0.65 mm) did not affect the size of dopamine pools but increased the conversion of [14c] dopa to [14c] dopamine and the formation of [14c] dopac. |
1978-04-26 |
2023-08-11 |
Not clear |
| P Muller, P Seema. Brain neurotransmitter receptors after long-term haloperidol: dopamine, acetylcholine, serotonin, alpha-noradrenergic and naloxone receptors. Life sciences. vol 21. issue 12. 1978-04-17. PMID:203807. |
brain neurotransmitter receptors after long-term haloperidol: dopamine, acetylcholine, serotonin, alpha-noradrenergic and naloxone receptors. |
1978-04-17 |
2023-08-11 |
Not clear |
| P Seeman, J L Tedesco, T Lee, M Chau-Wong, P Muller, J Bowles, P M Whitaker, C McManus, M Tittler, P Weinreich, W C Friend, G M Brow. Dopamine receptors in the central nervous system. Federation proceedings. vol 37. issue 2. 1978-04-17. PMID:414936. |
dopamine receptors in the central nervous system can be studied by measuring the specific binding of [3h]dopamine, [3h]haloperidol, d-[3h]lsd, [3h]dihydroergocryptine or [3h]apomorphine. |
1978-04-17 |
2023-08-11 |
rat |
| P Seeman, J L Tedesco, T Lee, M Chau-Wong, P Muller, J Bowles, P M Whitaker, C McManus, M Tittler, P Weinreich, W C Friend, G M Brow. Dopamine receptors in the central nervous system. Federation proceedings. vol 37. issue 2. 1978-04-17. PMID:414936. |
prolonged exposure in vitro of caudate homogenate to high concentrations of dopamine leads to increased binding of [3h]apomorphine or [3h]haloperidol, suggesting receptor "sensitization." |
1978-04-17 |
2023-08-11 |
rat |
| E S Garnett, G Firnau, P K Chan, S Sood, L W Belbec. [18F]fluoro-dopa, an analogue of dopa, and its use in direct external measurements of storage, degradation, and turnover of intracerebral dopamine. Proceedings of the National Academy of Sciences of the United States of America. vol 75. issue 1. 1978-04-17. PMID:415309. |
alpha-methyl-dopa, a competitive inhibitor of dopa transport and decarboxylation, prevented the accumulation of (18)f; reserpine, known to release stored intracerebral dopamine, discharged (18)f; pargyline, a monoamine oxidase inhibitor, and haloperidol, a known augmentor of intracerebral dopamine turnover, increased the rate of accumulation of (18)f. these changes in the accumulation of intracerebral (18)f, after [(18)f]fluoro-dopa, were commensurate with the known action of the drugs used to induce them and demonstrate the use of a gamma-emitting precursor of a neurotransmitter to monitor simply, atraumatically, and externally the intracerebral metabolism of the transmitter in fully conscious primates. |
1978-04-17 |
2023-08-11 |
rat |
| L Ahtee, S Kaakkol. Effect of mecamylamine on the fate of dopamine in striatal and mesolimbic areas of rat brain; interaction with morphine and haloperidol. British journal of pharmacology. vol 62. issue 2. 1978-04-17. PMID:564219. |
effect of mecamylamine on the fate of dopamine in striatal and mesolimbic areas of rat brain; interaction with morphine and haloperidol. |
1978-04-17 |
2023-08-11 |
rat |
| L Ahtee, S Kaakkol. Effect of mecamylamine on the fate of dopamine in striatal and mesolimbic areas of rat brain; interaction with morphine and haloperidol. British journal of pharmacology. vol 62. issue 2. 1978-04-17. PMID:564219. |
1 the effects of the nicotinic cholinoceptor blocking drug, mecamylamine (alone or in combination with morphine or haloperidol) were investigated on the striatal homovanillic acid (hva) concentration and on the alpha-methyl-p-tyrosine (ampt)-induced depletion of striatal or mesolimbic dopamine content in the brain of rats. |
1978-04-17 |
2023-08-11 |
rat |
| L Ahtee, S Kaakkol. Effect of mecamylamine on the fate of dopamine in striatal and mesolimbic areas of rat brain; interaction with morphine and haloperidol. British journal of pharmacology. vol 62. issue 2. 1978-04-17. PMID:564219. |
3 mecamylamine (2 and 8 mg/kg) slowed the rate of ampt-induced depletion of dopamine from the striatum and mesolimbic area both in the brain of control rats treated with morphine or haloperidol. |
1978-04-17 |
2023-08-11 |
rat |
| F Llados, P Zapat. Effects of dopamine analogues and antagonists on carotid body chemosensors in situ. The Journal of physiology. vol 274. 1978-04-17. PMID:625005. |
dose-response curves for dopamine and apomorphine inhibition were displaced to the right by administration of phenothiazines (chlorpromazine and perphenazine) and butyrophenones (haloperidol and spiroperidol). |
1978-04-17 |
2023-08-11 |
Not clear |
| Y Furuta, K Hashimoto, M Washizak. beta-Adrenoceptor stimulation of exocrine secretion from the rat pancreas. British journal of pharmacology. vol 62. issue 1. 1978-03-29. PMID:202364. |
4 haloperidol (10 mg/kg) failed to suppress the secretory effect of dopamine on the exocrine pancreas but abolished the dopamine-induced hypotension. |
1978-03-29 |
2023-08-11 |
rat |
| A Mugelli, F Ledda, L Mantelli, M Torrini, T Maccion. Studies on the positive inotropic effect of dopamine in the guinea-pig heart. Naunyn-Schmiedeberg's archives of pharmacology. vol 301. issue 1. 1978-03-29. PMID:600319. |
in preparations obtained from animals pretreated with reserpine (2.5 mg/kg, 24 h prior to the experiment) the dose-response curve was not significantly affected by haloperidol, a dopamine vascular receptor antagonist (10(-6)-3x10(-6) m). |
1978-03-29 |
2023-08-11 |
Not clear |
| A Mugelli, F Ledda, L Mantelli, M Torrini, T Maccion. Studies on the positive inotropic effect of dopamine in the guinea-pig heart. Naunyn-Schmiedeberg's archives of pharmacology. vol 301. issue 1. 1978-03-29. PMID:600319. |
in preparations in which fast sodium channels were blocked by k+ -rich medium, slow electrical responses (calcium-mediated action potentials) as well as contractions were induced by high concentrations of dopamine (10(-4)-3x10(-4) m); again these responses were unaffected by phentolamine or haloperidol, but were blocked by practolol. |
1978-03-29 |
2023-08-11 |
Not clear |
| R F Butterworth, M Gonce, A Barbea. Platelet dopamine uptake in Huntington's chorea and Gilles de la Tourette's syndrome: effect of haloperidol. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 4. issue 4. 1978-03-21. PMID:145893. |
platelet dopamine uptake in huntington's chorea and gilles de la tourette's syndrome: effect of haloperidol. |
1978-03-21 |
2023-08-11 |
human |
| G J Trachte, A M Lefe. Influence of dopamine on liver dynamics in hemorrhagic shock. Circulatory shock. vol 4. issue 4. 1978-03-21. PMID:598004. |
the increase in hepatic artery and portal vein flows appeared to result from stimulation of dopaminergic receptors since the dopamine dose was in the dopaminergic range and because haloperidol, a dopamine blocker, abolished the improved hemodynamic effects of dopamine. |
1978-03-21 |
2023-08-11 |
Not clear |
| O S Steinsland, J P Hiebl. Dopaminergic inhibition of adrenergic neurotransmission as a model for studies on dopamine receptor mechanisms. Science (New York, N.Y.). vol 199. issue 4327. 1978-02-23. PMID:22933. |
the inhibitory action of both dopamine and apomorphine was competitively antagonized by haloperidol and several other antipsychotic drugs. |
1978-02-23 |
2023-08-11 |
rabbit |
| O S Steinsland, J P Hiebl. Dopaminergic inhibition of adrenergic neurotransmission as a model for studies on dopamine receptor mechanisms. Science (New York, N.Y.). vol 199. issue 4327. 1978-02-23. PMID:22933. |
the calculated affinities of these drugs for the dopaminergic receptor correlate closely with both the pharmacological potencies of these drugs in vivo and their reported potencies as inhibitors of [3h]haloperidol binding to "dopamine receptors" in brain homogenates. |
1978-02-23 |
2023-08-11 |
rabbit |
| A Smialowsk. The effect of apomorphine injection into caudate nucleus on electrical activity of some structures of the rabbit brain. Polish journal of pharmacology and pharmacy. vol 29. issue 5. 1978-02-18. PMID:593964. |
apomorphine, dopamine, or haloperidol were injected into the caudate nucleus of wakeful rabbits at a volume of 2 microliter. |
1978-02-18 |
2023-08-11 |
rabbit |
| P Zarzecki, D J Blake, G G Somje. Neurological disturbances, nigrostriate synapses, and iontophoretic dopamine and apomorphine after haloperidol. Experimental neurology. vol 57. issue 3. 1978-01-27. PMID:200450. |
neurological disturbances, nigrostriate synapses, and iontophoretic dopamine and apomorphine after haloperidol. |
1978-01-27 |
2023-08-11 |
Not clear |
| C Bell, G Matalani. Dopamine-induced depression of adrenergic nerve-mediated contraction of smooth muscle. British journal of pharmacology. vol 61. issue 2. 1978-01-27. PMID:922257. |
2 the depressant effect of dopamine was prevented in the presence of haloperidol (0.1 micrometer) but not in the presence of phentolamine (0.03-0.14 micrometer). |
1978-01-27 |
2023-08-11 |
rabbit |
| C Bell, G Matalani. Dopamine-induced depression of adrenergic nerve-mediated contraction of smooth muscle. British journal of pharmacology. vol 61. issue 2. 1978-01-27. PMID:922257. |
however, in this tissue the effect of dopamine was prevented by phentolamine but not affected by haloperidol. |
1978-01-27 |
2023-08-11 |
rabbit |