| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R T Bartu. Short-term memory in the rhesus monkey: effects of dopamine blockade via acute haloperidol administration. Pharmacology, biochemistry, and behavior. vol 9. issue 3. 1979-01-15. PMID:101990. |
short-term memory in the rhesus monkey: effects of dopamine blockade via acute haloperidol administration. |
1979-01-15 |
2023-08-11 |
monkey |
| B Biswas, A Carlsso. Potentiation by neuroleptic agents of the inhibitory action of intraperitoneally administered GABA on the locomotor activity of mice. Pharmacology, biochemistry, and behavior. vol 8. issue 6. 1978-12-02. PMID:29313. |
haloperidol, chlorpromazine, thioridazine, and clozapine, but not the apparently selective dopamine receptor-blocking agent spiperone, were found to possess such activity. |
1978-12-02 |
2023-08-11 |
mouse |
| P Moleman, J Bruinvels, C F van Valkenbur. Haloperidol inhibits the disappearance of acidic dopamine metabolites from rat striatum. The Journal of pharmacy and pharmacology. vol 30. issue 9. 1978-11-29. PMID:29101. |
haloperidol inhibits the disappearance of acidic dopamine metabolites from rat striatum. |
1978-11-29 |
2023-08-11 |
rat |
| G M Baca, G C Palme. Presence of hormonally-sensitive adenylate cyclase receptors in capillary-enriched fractions from rat cerebral cortex. Blood vessels. vol 15. issue 5. 1978-11-29. PMID:210869. |
haloperidol was seen to be a potent inhibitor of either dopamine- or dopamine agonist-sensitive adenylate cyclase. |
1978-11-29 |
2023-08-11 |
rat |
| G A Gudelsky, L Annunziato, K E Moor. Localization of the site of the haloperidol-induced, prolactin-mediated increase of dopamine turnover in the median eminence: studies in rats with complete hypothalamic deafferentations. Journal of neural transmission. vol 42. issue 3. 1978-11-27. PMID:690628. |
the isolation of tuberoinfundibular neurons from the rest of the brain did not alter the ability of haloperidol to increase the rate of alpha-methyltyrosine-induced decline of dopamine in the median eminence. |
1978-11-27 |
2023-08-11 |
rat |
| B Scatton, P Worm. Subsensitivity of striatal and mesolimbic dopamine target cells after repeated treatment with apomorphine dipivaloyl ester. Naunyn-Schmiedeberg's archives of pharmacology. vol 303. issue 3. 1978-10-18. PMID:567284. |
similarly, a shift to the left of the haloperidol dose-response curve for the increase in striatal dopamine metabolite levels was observed in rats treated subacutely with the ester as compared to control rats. |
1978-10-18 |
2023-08-11 |
rat |
| W Hoss, J H Reese, C Smile. Binding of apomorphine to neural membranes. Journal of neuroscience research. vol 3. issue 4. 1978-09-29. PMID:615274. |
butyrophenones have the highest affinities for these sites--kd = 43 micrometer for haloperidol--while dopamine and dopamine releasers and reuptake blockers, as well as a variety of other alkaloids, have much lower affinities. |
1978-09-29 |
2023-08-11 |
Not clear |
| D J Boullin, D Molyneux, B Roac. The binding of haloperidol to human blood platelets and interactions with 5-hydroxytryptamine and dopamine. British journal of pharmacology. vol 63. issue 3. 1978-09-29. PMID:667500. |
the binding of haloperidol to human blood platelets and interactions with 5-hydroxytryptamine and dopamine. |
1978-09-29 |
2023-08-11 |
human |
| R A Steiner, P Illner, A D Rolfs, P T Toivola, C C Gal. Noradrenergic and dopaminergic regulation of GH and prolactin in baboons. Neuroendocrinology. vol 26. issue 1. 1978-09-25. PMID:209362. |
infusion of dopamine (da), norepinephrine (ne), thyrotropin-releasing hormone (trh), phentolamine, haloperidol, and inhibitors of da-beta-hydroxylase and peripheral decarboxylase. |
1978-09-25 |
2023-08-11 |
Not clear |
| T O De Roij, J Frens, F Woutersen-Van-Nijnanten, M Vianen-Meijerin. Comparison of the thermoregulatory responses to intracerebroventricularly injected dopamine, noradrenaline and 5-hydroxytryptamine in the goat. European journal of pharmacology. vol 49. issue 4. 1978-09-25. PMID:668811. |
the thermoregulatory responses to dopamine (da), noradrenaline (na) and 5-hydroxytryptamine (5-ht), injected into the third cerebral ventricle of goats at 20 degrees c ambient temperature (ta) or during cold exposure, were compared before and after pretreatment with the da receptor blocker haloperidol or the 5-ht receptor blocker methysergide. |
1978-09-25 |
2023-08-11 |
Not clear |
| B V Clineschmidt, J C McGuffin, A B Pflueger, J A Totar. A 5-hydroxytryptamine-like mode of anorectic action for 6-chloro-2-[1-piperazinyl]-pyrazine (MK-212). British journal of pharmacology. vol 62. issue 4. 1978-08-28. PMID:656703. |
5 haloperidol, which blocks receptors for dopamine, antagonized the anorexigenic effect of amphetamine, but was ineffective in offsetting the action of mk-212, 3 mg/kg. |
1978-08-28 |
2023-08-11 |
rat |
| W C Friend, G M Brown, G Jawahir, T Lee, P Seema. Effect of haloperidol and apomorphine treatment on dopamine receptors in pituitary and striatum. The American journal of psychiatry. vol 135. issue 7. 1978-08-14. PMID:665797. |
effect of haloperidol and apomorphine treatment on dopamine receptors in pituitary and striatum. |
1978-08-14 |
2023-08-11 |
rat |
| M J Kukla, C M Woo, J R Kehr, A Mille. 5-Chloro-2-phenyl-1-benzo[b]thiophene-3-alkanimines, potential antipsychotic agents. Journal of medicinal chemistry. vol 21. issue 4. 1978-07-24. PMID:25967. |
they were evaluated in dopamine and haloperidol receptor assays. |
1978-07-24 |
2023-08-11 |
Not clear |
| R C Smith, N Narasimhachari, J M Davi. Increased effect of apomorphine on homovanillic acid in rats terminated from chronic haloperidol. Journal of neural transmission. vol 42. issue 2. 1978-07-24. PMID:650206. |
this finding is consistent with the behavioral evidence suggesting supersensitivity of post-synaptic dopamine receptors after termination of chronic haloperidol. |
1978-07-24 |
2023-08-11 |
rat |
| A Hitri, W J Weiner, R L Borison, B I Diamond, P A Nausieda, H L Klawan. Dopamine binding following prolonged haloperidol pretreatment. Annals of neurology. vol 3. issue 2. 1978-07-24. PMID:655662. |
dopamine binding following prolonged haloperidol pretreatment. |
1978-07-24 |
2023-08-11 |
rat |
| A Hitri, W J Weiner, R L Borison, B I Diamond, P A Nausieda, H L Klawan. Dopamine binding following prolonged haloperidol pretreatment. Annals of neurology. vol 3. issue 2. 1978-07-24. PMID:655662. |
the number of binding sites for tritiated dopamine as well as the affinity of 3h-dopamine for dopamine receptors was studied in rats chronically pretreated with the neuroleptic haloperidol. |
1978-07-24 |
2023-08-11 |
rat |
| J S Kizer, J Humm, G Nicholson, G Greeley, W Youngbloo. The effect of castration, thyroidectomy and haloperidol upon the turnover rates of dopamine and norepinephrine and the kinetic properties of tyrosine hydroxylase in discrete hypothalamic nuclei of the male rat. Brain research. vol 146. issue 1. 1978-07-15. PMID:25696. |
the effect of castration, thyroidectomy and haloperidol upon the turnover rates of dopamine and norepinephrine and the kinetic properties of tyrosine hydroxylase in discrete hypothalamic nuclei of the male rat. |
1978-07-15 |
2023-08-11 |
rat |
| J S Kizer, J Humm, G Nicholson, G Greeley, W Youngbloo. The effect of castration, thyroidectomy and haloperidol upon the turnover rates of dopamine and norepinephrine and the kinetic properties of tyrosine hydroxylase in discrete hypothalamic nuclei of the male rat. Brain research. vol 146. issue 1. 1978-07-15. PMID:25696. |
adult male rats were either castrated, thyroidectomized, or treated with haloperidol and the rates of turnover of dopamine (da) and norepinephrine (ne) in the median eminence (me), the arcuate and dorsomedial nuclei of the hypothalamus were estimated from the rate of decay of da and ne concentrations as determined by radioenzymatic assay following blockade of catecholamine synthesis by alpha-methyl-p-tyrosine. |
1978-07-15 |
2023-08-11 |
rat |
| F J Tilders, P G Smeli. Effects of hypothalamic lesions and drugs interfering with dopaminergic transmission on pituitary MSH content of rats. Neuroendocrinology. vol 25. issue 5. 1978-07-15. PMID:206853. |
haloperidol and pimozide (both neuroleptics) were used to block specifically dopamine (da)-receptors. |
1978-07-15 |
2023-08-11 |
rat |
| M Titeler, P Weinreich, D Sinclair, P Seema. Multiple receptors for brain dopamine. Proceedings of the National Academy of Sciences of the United States of America. vol 75. issue 3. 1978-07-15. PMID:418405. |
the inhibitions of two agonist radioligands ([3h]dopamine, [3h]apomorphine) by haloperidol, chlorpromazine, or piflutixol were biphasic. |
1978-07-15 |
2023-08-11 |
Not clear |