| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G M Brown, P Seeman, T Le. Dopamine/neuroleptic receptors in basal hypothalamus and pituitary. Endocrinology. vol 99. issue 5. 1977-01-29. PMID:991828. |
the pituitary receptors for (3h)haloperidol and (3h)dopamine have the characteristics of a functional system. |
1977-01-29 |
2023-08-11 |
rat |
| M C Carrara, A D Baine. Propranolol induces acute natriuresis by beta blockade and dopaminergic stimulation. Canadian journal of physiology and pharmacology. vol 54. issue 5. 1977-01-28. PMID:11039. |
haloperidol and pimozide, both dopamine blocking agents with minimal beta blocking effects, prevented the natriuretic response. |
1977-01-28 |
2023-08-11 |
rat |
| B Costall, R J Naylo. A comparison of the abilities of typical neuroleptic agents and of thioridazine, clozapine, sulpiride and metoclopramide to antagonise the hyperactivity induced by dopamine applied intracerebrally to areas of the extrapyramidal and mesolimbic systems. European journal of pharmacology. vol 40. issue 1. 1977-01-28. PMID:791660. |
haloperidol, fluphenazine and pimozide were shown to antagonise, in a dose-dependent manner, the hyperactivity induced by dopamine from all 3 areas. |
1977-01-28 |
2023-08-11 |
rat |
| M L Smee, D H Overstree. Alterations in the effects of dopamine agonists and antagonists on general activity in rats following chronic morphine treatment. Psychopharmacology. vol 49. issue 2. 1977-01-25. PMID:825898. |
the dose-response curve for haloperidol, another dopamine antagonist, was unchanged. |
1977-01-25 |
2023-08-11 |
rat |
| D R Burt, I Creese, S H Snyde. Properties of [3H]haloperidol and [3H]dopamine binding associated with dopamine receptors in calf brain membranes. Molecular pharmacology. vol 12. issue 5. 1977-01-25. PMID:995128. |
properties of [3h]haloperidol and [3h]dopamine binding associated with dopamine receptors in calf brain membranes. |
1977-01-25 |
2023-08-11 |
Not clear |
| H Satoh, Y Satoh, Y Notsu, F Hond. Adenosine 3',5'-cyclic monophosphate as a possible mediator of rotational behaviour induced by dopaminergic receptor stimulation in rats lesioned unilaterally in the substantia nigra. European journal of pharmacology. vol 39. issue 2. 1977-01-03. PMID:185065. |
the activation by dopamine was blocked by haloperidol. |
1977-01-03 |
2023-08-11 |
rat |
| H S Ahn, R K Mishra, C Demirjian, M H Makma. Catecholamine-sensitive adenylate cyclase in frontal cortex of primate brain. Brain research. vol 116. issue 3. 1977-01-03. PMID:824023. |
this latter system differs from more typical dopamine receptors found in caudate, retina and limbic cortex in that (a) it is not stimulated by 1-(3,4-dihydroxybenzyl)-4-(2-pyrimidinyl) piperazine (s584); (b) it is stimulated significantly by the putative alpha-receptor agonist, clonidine; (c) it is more sensitive to blockade by clozapine than primate retina or caudate; also the sensitivity to haloperidol is greater than has been reported for non-primate caudate; (d) it is very sensitive to stimulation by norepinephrine and to blockade by phentolamine (an alpha-receptor blocker). |
1977-01-03 |
2023-08-11 |
monkey |
| T E Bridges, E W Hillhouse, M T Jone. The effect of dopamine on neurohypophysial hormone release in vivo and from the rat neural lobe and hypothalamus in vitro. The Journal of physiology. vol 260. issue 3. 1977-01-03. PMID:988183. |
the hormone release induced in vivo by dopamine could be prevented by the prior administration of haloperidol or phentolamine and these antagonists were equally effective in blocking the hormone release due to noradrenaline. |
1977-01-03 |
2023-08-11 |
rat |
| K Hashimoto, J Takahara, H Hosogi, N Ofuji, T Yasuhar. [In vitro assay for ACTH-releasing activity using ACTH radioimmunoassay: ACTH releasing activities by various drugs (author's transl)]. Nihon Naibunpi Gakkai zasshi. vol 52. issue 2. 1976-12-30. PMID:185101. |
using this method, it found that lvp, avp, norepinephrine (100 ng/ml200 ng/ml) and 5-hydroxytryptophane (1 mug/ml) had acth releasing activities but lh-rh, trh, glucagon, dopamine, phentolamine, propranolol, haloperidol, prostaglandin e1 and indomethacin did not affect the release of acth. |
1976-12-30 |
2023-08-11 |
human |
| A Simon, E F Van Maane. Dopamine receptors and dopaminergic nerves in the vas deferens of the rat. Archives internationales de pharmacodynamie et de therapie. vol 222. issue 1. 1976-12-30. PMID:984969. |
haloperidol had a pa2 value of 7.3 against dopamine and 6.5 against noradrenaline. |
1976-12-30 |
2023-08-11 |
rat |
| A Carlsson, W Kehr, M Lindqvis. The role of intraneuronal amine levels in the feedback control of dopamine, noradrenaline and 5-hydroxytryptamine synthesis in rat brain. Journal of neural transmission. vol 39. issue 1-2. 1976-12-30. PMID:1086343. |
the influence of varying levels of dopamine and noradrenaline on the synthesis of these amines could still be demonstrated after blockade of dopamine receptos and of alpha-adrenergic (noradrenaline) receptors by haloperidol, suggesting that the mechanism involved in this feedback control is mediated via end-product inhibition of tyrosine hydroxylase. |
1976-12-30 |
2023-08-11 |
rat |
| B Costall, R J Naylor, R M Pinde. Hyperactivity induced by tetrahydroisoquinoline derivatives injected into the nucleus accumbens. European journal of pharmacology. vol 39. issue 1. 1976-11-21. PMID:134899. |
both effects developed within 1-2 h and persisted for at least 6 h. the hyperactivity induced by dopamine was antagonised in a dose-dependent manner by haloperidol: propranolol and aceperone were without effect. |
1976-11-21 |
2023-08-11 |
rat |
| I Kääriäine. Effects of aminooxyacetic acid and baclofen on the catalepsy and on the increase of mesolimbic and striatal dopamine turnover induced by haloperidol in rats. Acta pharmacologica et toxicologica. vol 39. issue 3. 1976-11-21. PMID:989685. |
effects of aminooxyacetic acid and baclofen on the catalepsy and on the increase of mesolimbic and striatal dopamine turnover induced by haloperidol in rats. |
1976-11-21 |
2023-08-11 |
rat |
| V V Murthy, J C Gilbert, L I Goldberg, J F Ku. Dopamine-sensitive adenylate cyclase in canine renal artery. The Journal of pharmacy and pharmacology. vol 28. issue 7. 1976-11-01. PMID:8611. |
in tissue from the phenoxybenzamine-pretreated dog, the sitmulatroy effect of dopamine on the renal artery enzyme was selectively blocked by 0-01 mum haloperidol, but not by 0-2 mum propranolol. |
1976-11-01 |
2023-08-11 |
dog |
| W Keh. [Interactions of dopamine receptor agonists and antagonists with regard to dopamine synthesis and metabolism]. Arzneimittel-Forschung. vol 26. issue 6. 1976-11-01. PMID:9107. |
also, amphetamine potentiated the haloperidol induced increase in dopamine release in vivo measured as 3-methoxytyramine formation. |
1976-11-01 |
2023-08-11 |
rat |
| J Korf, P H Boer, D Fekke. CYCLIC AMP/*SECRETl cyclic AMP into push-pull perfusates in freely moving rats. Brain research. vol 113. issue 3. 1976-11-01. PMID:182325. |
the effects of noradrenaline and dopamine on cyclic amp were found to be mediated by different receptors: haloperidol antagonized only the dopamine response. |
1976-11-01 |
2023-08-11 |
rat |
| D M Atrens, T Ljungberg, U Ungersted. Modulation of reward and aversion processes in the rat diencephalon by neuroleptics: differential effects of clozapine and haloperidol. Psychopharmacology. vol 49. issue 1. 1976-11-01. PMID:822454. |
consequently, the attenuation of self-stimulation produced by haloperidol does not indicate a direct role for dopamine in modulating reward. |
1976-11-01 |
2023-08-11 |
rat |
| G P Mueller, J Simpkins, J Meites, K E Moor. Differential effects of dopamine agonists and haloperidol on release of prolactin, thyroid stimulating hormone, growth hormone and luteinizing hormone in rats. Neuroendocrinology. vol 20. issue 2. 1976-11-01. PMID:958594. |
differential effects of dopamine agonists and haloperidol on release of prolactin, thyroid stimulating hormone, growth hormone and luteinizing hormone in rats. |
1976-11-01 |
2023-08-11 |
rat |
| G P Mueller, J Simpkins, J Meites, K E Moor. Differential effects of dopamine agonists and haloperidol on release of prolactin, thyroid stimulating hormone, growth hormone and luteinizing hormone in rats. Neuroendocrinology. vol 20. issue 2. 1976-11-01. PMID:958594. |
the dose-response effects of apomorphine and et-495 (piribedil), 2 specific dopamine (da) receptor stimulators, and haloperidol, a da receptor blocker, were tested on the secretion of prolactin (prl), thyroid stimulating hormone (tsh), growth hormone (gh) and luteinizing hormone (lh) in male rats. |
1976-11-01 |
2023-08-11 |
rat |
| L Candelis. [Haloperidol, reserpine, l-dopa and amantidine in the treatment of Huntington chorea (author's transl)]. Rivista di patologia nervosa e mentale. vol 96. issue 1. 1976-10-20. PMID:134449. |
two drugs that should reduce striatal dopamine activity (haloperidol and reserpine) and two other drugs that should increase it (l-dopa and amantadine) have been successively adminstered to six patients suffering from huntington's chorea. |
1976-10-20 |
2023-08-11 |
Not clear |