| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K K Maitra, P Seth, H G Ross, M Thewissen, D K Gangul. Presynaptic dopaminergic inhibition of the spinal reflex in rats. Brain research bulletin. vol 28. issue 5. 1992-08-05. PMID:1352179. |
on the reflex could be reversed by the dopaminergic antagonist haloperidol (0.5 mg/kg, i.v.). |
1992-08-05 |
2023-08-11 |
rat |
| E Toth, H Sershen, A Hashim, E S Vizi, A Lajth. Effect of nicotine on extracellular levels of neurotransmitters assessed by microdialysis in various brain regions: role of glutamic acid. Neurochemical research. vol 17. issue 3. 1992-08-05. PMID:1352387. |
the cholinergic antagonists mecamylamine and atropine, the dopaminergic antagonists haloperidol and sulpiride, and the excitatory amino acid antagonist kynurenic acid all inhibited the nicotine-induced increase of extracellular dopamine in the striatum. |
1992-08-05 |
2023-08-11 |
rat |
| Y Matsumoto, H Okamura, Y Ichitani, N Yanaihara, T Nakajima, Y Ibat. Immunocytochemical survey of haloperidol-induced immunoreactive changes of [Met]enkephalin-Arg6-Gly7-Leu8 in the rat forebrain. Brain research bulletin. vol 28. issue 5. 1992-08-05. PMID:1617455. |
these findings suggest that haloperidol influences enkephalinergic neurons region specifically and that in the dorsal and ventral striopallidal enkephalinergic system haloperidol increases meagl immunoreactivity in cell bodies, fibers, and terminals by blocking intrastriatal dopaminergic neurotransmission. |
1992-08-05 |
2023-08-11 |
rat |
| R J Care. Pavlovian conditioning of L-dopa induced movement. Psychopharmacology. vol 107. issue 2-3. 1992-07-30. PMID:1615121. |
additionally, drug tests with the combined dopaminergic receptor antagonists, sch 23390 (0.1 mg/kg) and haloperidol (0.5 mg/kg), at doses sufficient to block spontaneous behavior and l-dopa (20 mg/kg)-induced rotation, revealed that the conditioned contralateral rotation response, unlike l-dopa-induced contralateral rotation, is not affected by d1/d2 receptor blockade. |
1992-07-30 |
2023-08-11 |
rat |
| S Li, G Pelletie. Role of dopamine in the regulation of gonadotropin-releasing hormone in the male rat brain as studied by in situ hybridization. Endocrinology. vol 131. issue 1. 1992-07-27. PMID:1612019. |
the effects of the dopaminergic antagonist haloperidol (hal) as well as the d2 dopamine receptor agonist bromocriptine (bro) on gnrh messenger rna (mrna) levels in the male rat were investigated by quantitative in situ hybridization. |
1992-07-27 |
2023-08-11 |
rat |
| M B Lazarova-Bakarova, B P Petkova, I K Todorov, V D Petko. Memory impairment induced by combined disturbance of noradrenergic and dopaminergic neurotransmissions: effects of nootropic drugs. Acta physiologica et pharmacologica Bulgarica. vol 17. issue 1. 1992-06-22. PMID:1667717. |
the effect of the combined application of the alpha 2-adrenoreceptor agonist clonidine and of the dopaminergic blocker haloperidol on the memory processes was tested on albino rats. |
1992-06-22 |
2023-08-11 |
rat |
| M B Lazarova-Bakarova, B P Petkova, I K Todorov, V D Petko. Memory impairment induced by combined disturbance of noradrenergic and dopaminergic neurotransmissions: effects of nootropic drugs. Acta physiologica et pharmacologica Bulgarica. vol 17. issue 1. 1992-06-22. PMID:1667717. |
the paper discusses the role of the noradrenergic and dopaminergic neurotransmitter systems for the amnestic effect of the clonidine + haloperidol combination, as well as for the favourable effect on the cognitive functions of the tested nootropic drugs adafenoxate and p-p. |
1992-06-22 |
2023-08-11 |
rat |
| I Jibiki, H Matsuda, N Yamaguchi, K Kurokawa, K Hisad. Acutely administered haloperidol-induced widespread reduction of regional cerebral blood flow observed from subtraction of brain imaging with single photon emission computed tomography using technetium-99m hexamethyl-propyleneamine oxime. Neuropsychobiology. vol 24. issue 3. 1992-05-21. PMID:2135067. |
the widespread cortical reduction is considered to be due to a nonspecific or indirect effect of haloperidol in view of the broad action sites inconsistent with the known anatomy of the mesocortical dopaminergic system. |
1992-05-21 |
2023-08-11 |
human |
| b' V R Paunovi\\xc4\\x87, I Timotijevi\\xc4\\x87, D Marinkovi\\xc4\\x8. Neuroleptic actions on the thyroid axis: different effects of clozapine and haloperidol. International clinical psychopharmacology. vol 6. issue 3. 1992-05-11. PMID:1806619.' |
the results obtained are discussed in terms of the different pharmacological profiles of haloperidol and clozapine, especially regarding their dopaminergic actions, alpha-adrenergic and serotonergic control upon thyroid axis. |
1992-05-11 |
2023-08-11 |
Not clear |
| X Z Ding, I Mocchett. Dopaminergic regulation of cholecystokinin mRNA content in rat striatum. Brain research. Molecular brain research. vol 12. issue 1-3. 1992-04-13. PMID:1312208. |
haloperidol, a dopaminergic receptor blocker, injected at 1 mg/kg, i.p., daily for 7 days, decreased cck mrna content in striatum but not in the cerebral cortex. |
1992-04-13 |
2023-08-11 |
rat |
| X Z Ding, I Mocchett. Dopaminergic regulation of cholecystokinin mRNA content in rat striatum. Brain research. Molecular brain research. vol 12. issue 1-3. 1992-04-13. PMID:1312208. |
moreover, haloperidol blocked the effect of cocaine and benztropine, suggesting that the stimulation of striatal dopaminergic receptors is necessary for the induction of cck biosynthesis. |
1992-04-13 |
2023-08-11 |
rat |
| K K Maitra, P Seth, K P Mohanakumar, D K Gangul. Supersensitivity of spinal dopaminergic receptors in rat after chronic haloperidol. Brain research bulletin. vol 28. issue 1. 1992-04-09. PMID:1540840. |
supersensitivity of spinal dopaminergic receptors in rat after chronic haloperidol. |
1992-04-09 |
2023-08-11 |
rat |
| K K Maitra, P Seth, K P Mohanakumar, D K Gangul. Supersensitivity of spinal dopaminergic receptors in rat after chronic haloperidol. Brain research bulletin. vol 28. issue 1. 1992-04-09. PMID:1540840. |
in order to examine the effect of chronic neuroleptics on spinal dopaminergic system, rats were treated with haloperidol (0.5 mg/kg ip) for 21 days and the monosynaptic mass reflex (mmr) as well as dopamine (da) metabolism were investigated. |
1992-04-09 |
2023-08-11 |
rat |
| G S Robertson, H C Fibige. Neuroleptics increase c-fos expression in the forebrain: contrasting effects of haloperidol and clozapine. Neuroscience. vol 46. issue 2. 1992-04-08. PMID:1347406. |
destruction of mesotelencephalic dopaminergic neurons with 6-hydroxydopamine abolished the increase in fos expression in the nucleus accumbens and striatum produced by haloperidol and raclopride, and also blocked the clozapine-induced increase in the nucleus accumbens. |
1992-04-08 |
2023-08-11 |
Not clear |
| C Messier, O Mrabet, C Destrad. Locomotor bias produced by intra-accumbens injection of dopamine agonists and antagonists. Pharmacology, biochemistry, and behavior. vol 41. issue 1. 1992-04-02. PMID:1347172. |
to further evaluate the contribution of dopaminergic function in the accumbens to the direction of locomotion, we first compared the effect on the direction of locomotor activity of unilateral intra-accumbens injections of the nonspecific da antagonist haloperidol, the specific d-1 antagonist sch-23390, the specific d-2 antagonist metoclopramide. |
1992-04-02 |
2023-08-11 |
Not clear |
| C Mandal, C Mandal, C Harrington, M Adamczyk, D S Linthicu. Kinetics of haloperidol binding to monoclonal antibodies as measured by direct fluorescence quenching. Biochemical pharmacology. vol 43. issue 4. 1992-04-02. PMID:1540239. |
we report here the kinetic and equilibrium characteristics of ligand-antibody complexes of haloperidol, a dopaminergic antagonist, with three of its monoclonal antibodies as studied by fluorescence quenching techniques. |
1992-04-02 |
2023-08-11 |
Not clear |
| R Rivest, C A Marsde. Muscarinic antagonists attenuate the increase in accumbens and striatum dopamine metabolism produced by clozapine but not by haloperidol. British journal of pharmacology. vol 104. issue 1. 1992-03-23. PMID:1786513. |
the results indicate that central muscarinic receptors are involved in the actions on dopaminergic function of clozapine but not haloperidol. |
1992-03-23 |
2023-08-11 |
rat |
| N Wang, D H Zhao, B H Shen. Positive inotropic effect of apomorphine on guinea pig myocardium is mediated by dopamine DA1 receptors. Zhongguo yao li xue bao = Acta pharmacologica Sinica. vol 12. issue 3. 1992-03-10. PMID:1781280. |
dopaminergic antagonist haloperidol antagonized the positive inotropic effect of apo. |
1992-03-10 |
2023-08-11 |
Not clear |
| K A Grant, J E Barret. Blockade of the discriminative stimulus effects of ethanol with 5-HT3 receptor antagonists. Psychopharmacology. vol 104. issue 4. 1992-03-09. PMID:1780414. |
in addition, the dopaminergic antagonist haloperidol and the 5-ht2 receptor antagonist ketanserin also failed to block the ethanol discrimination. |
1992-03-09 |
2023-08-11 |
Not clear |
| M Mavridis, F C Colpaert, M J Milla. Differential modulation of (+)-amphetamine-induced rotation in unilateral substantia nigra-lesioned rats by alpha 1 as compared to alpha 2 agonists and antagonists. Brain research. vol 562. issue 2. 1992-03-03. PMID:1685341. |
in rats sustaining unilateral 6-hydroxy-dopamine lesions of the substantia nigra (sn), the indirect dopaminergic agonist, (+)-amphetamine (amph), dose-dependently induced robust, ipsilateral rotation: this could be dose-dependently abolished by the dopamine (d2/d1) antagonist, haloperidol. |
1992-03-03 |
2023-08-11 |
rat |