| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Gaggi, R Cont, A M Giann. Comparison among the effects of nifedipine, nimodipine and nisoldipine on the brain biogenic amines of normal or haloperidol treated rats. General pharmacology. vol 24. issue 5. 1994-02-01. PMID:8270166. |
the small changes induced by the drugs on normal rats were markedly increased in the haloperidol treated rats, clearly showing an inhibition of dopaminergic systems. |
1994-02-01 |
2023-08-12 |
rat |
| B H Schmidt, F Chaoulof. Chronic treatment with an anxiolytic dose of the 5-HT1A agonist ipsapirone does not alter ipsapirone acute neuroendocrine effects. Psychoneuroendocrinology. vol 18. issue 7. 1994-01-27. PMID:7903466. |
moreover, ipsapirone pretreatment did not affect the increase in plasma prolactin levels elicited by the dopaminergic receptor antagonist haloperidol. |
1994-01-27 |
2023-08-12 |
rat |
| K K Pant, C Nat. Dopaminergic involvement in the effects of piracetam on foot shock induced aggression in mice. The Indian journal of medical research. vol 98. 1993-12-02. PMID:7901159. |
dopaminergic receptor blocker haloperidol (0.5; 0.25 and 0.12 mg/kg, ip) and pimozide (1.0 mg/kg, ip) produced inhibition of the aggressive behaviour. |
1993-12-02 |
2023-08-12 |
mouse |
| T P Shevchenko, B A Tolpyshev, L N Zban\. [The behavioral and neurochemical changes in rats caused by the subchronic administration of haloperidol]. Eksperimental'naia i klinicheskaia farmakologiia. vol 56. issue 3. 1993-12-01. PMID:8219980. |
rat experiments showed that subchronic haloperidol enhanced or perverted motor asymmetry appearing in response to apomorphine, resulted in imbalance between the dopaminergic and serotoninergic systems and increased norepinephrine levels. |
1993-12-01 |
2023-08-12 |
rat |
| E Castrén, M da Penha Berzaghi, D Lindholm, H Thoene. Differential effects of MK-801 on brain-derived neurotrophic factor mRNA levels in different regions of the rat brain. Experimental neurology. vol 122. issue 2. 1993-10-26. PMID:8405262. |
pentobarbital (an enhancer of gabaergic functions) and scopolamine (a muscarinic receptor antagonist) blocked the effects of mk-801 on bdnf mrna levels in the retrosplenial cortex, but the nicotinic and dopaminergic receptor antagonists mecamylamine and haloperidol, respectively, were ineffective. |
1993-10-26 |
2023-08-12 |
rat |
| C L Nilsson, E Eriksso. Haloperidol increases prolactin release and cyclic AMP formation in vitro: inverse agonism at dopamine D2 receptors? Journal of neural transmission. General section. vol 92. issue 2-3. 1993-10-12. PMID:7690232. |
it is suggested that haloperidol may act as an inverse agonist rather than as a neutral antagonist at dopaminergic d2 receptors. |
1993-10-12 |
2023-08-12 |
Not clear |
| J Caboche, P Vernier, M Rogard, M J Besso. Haloperidol increases PPE mRNA levels in the caudal part of the nucleus accumbens in the rat. Neuroreport. vol 4. issue 5. 1993-07-22. PMID:8513136. |
in this study, the effects of an interruption of dopamine transmission by haloperidol (a dopaminergic receptor antagonist) were examined in the rat nucleus accumbens. |
1993-07-22 |
2023-08-12 |
rat |
| B V Kumar, P S Sastr. Dopamine receptors in human foetal brains: characterization, regulation and ontogeny of [3H]spiperone binding sites in striatum. Neurochemistry international. vol 20. issue 4. 1993-07-15. PMID:1304871. |
spiperone binding sites were characterized in a 40-week-old foetal brain to be dopamine receptors by the following criteria: (1) it was localized in a crude mitochondrial pellet that included synaptosomes; (2) binding was saturable at 0.8 nm concentration; (3) dopaminergic antagonists spiperone, haloperidol, pimozide, trifluperazine and chlorpromazine competed for the binding with ic50 values in the range of 0.3-14 nm while agonists--apomorphine and dopamine gave ic50 values of 2.5 and 10 microm, respectively suggesting a d2 type receptor. |
1993-07-15 |
2023-08-11 |
human |
| B Levant, E B DeSouz. Differential pharmacological profile of striatal and cerebellar dopamine receptors labeled by [3H]quinpirole: identification of a discrete population of putative D3 receptors. Synapse (New York, N.Y.). vol 14. issue 1. 1993-07-15. PMID:8099762. |
dopaminergic compounds inhibited the specific binding of [3h]quinpirole in the caudate/putamen with the following rank order of potencies: spiperone > haloperidol > or = (+)butaclamol > or = quinpirole > or = 7-oh-dpat > or = bromocriptine > clozapine > (-)sulpiride. |
1993-07-15 |
2023-08-12 |
Not clear |
| G Pelletie. Regulation of proopiomelanocortin gene expression in rat brain and pituitary as studied by in situ hybridization. Annals of the New York Academy of Sciences. vol 680. 1993-07-15. PMID:8512219. |
the role of dopamine was investigated following the administration of the dopaminergic antagonist haloperidol and the d2 dopaminergic receptor agonist bromocriptine. |
1993-07-15 |
2023-08-12 |
rat |
| T I Lidsky, S P Banerje. Acute administration of haloperidol enhances dopaminergic transmission. The Journal of pharmacology and experimental therapeutics. vol 265. issue 3. 1993-07-14. PMID:8389855. |
acute administration of haloperidol enhances dopaminergic transmission. |
1993-07-14 |
2023-08-12 |
rat |
| T I Lidsky, S P Banerje. Acute administration of haloperidol enhances dopaminergic transmission. The Journal of pharmacology and experimental therapeutics. vol 265. issue 3. 1993-07-14. PMID:8389855. |
however, it is generally assumed that augmentation of dopaminergic transmission is precluded by haloperidol's postsynaptic actions. |
1993-07-14 |
2023-08-12 |
rat |
| T I Lidsky, S P Banerje. Acute administration of haloperidol enhances dopaminergic transmission. The Journal of pharmacology and experimental therapeutics. vol 265. issue 3. 1993-07-14. PMID:8389855. |
the present data suggest that acute administration of haloperidol actually augments dopaminergic activity due to relatively strong presynaptic actions and relatively weak postsynaptic blocking effects. |
1993-07-14 |
2023-08-12 |
rat |
| T I Lidsky, S P Banerje. Acute administration of haloperidol enhances dopaminergic transmission. The Journal of pharmacology and experimental therapeutics. vol 265. issue 3. 1993-07-14. PMID:8389855. |
it is plausible that this initial increase in dopaminergic transmission may participate in producing the neural changes evoked by chronic haloperidol administration that allow this drug to have antipsychotic potency. |
1993-07-14 |
2023-08-12 |
rat |
| T Scimonelli, M Marucco, M E Celi. Evidence for catecholaminergic control of alpha-melanotropin (alpha-MSH) content in hypothalamic areas. Acta physiologica, pharmacologica et therapeutica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y [de] la Asociacion Latinoamericana de Farmacologia. vol 42. issue 2. 1993-05-25. PMID:1363745. |
haloperidol (1.2mg/kg), a dopaminergic receptor antagonist, propranolol (6.0mg/kg) and yohimbine (10mg/kg) (non selective beta- and alpha 2-adrenergic antagonist drugs respectively) had no effect on the alpha-msh in any of the hypothalamic areas studied. |
1993-05-25 |
2023-08-11 |
rat |
| E Perez-Oso, E Arill. Effect of prenatal dopamine receptor blocking on somatostatin receptor binding in the developing rat brain. Brain research bulletin. vol 31. issue 1-2. 1993-04-22. PMID:8095841. |
pregnant sprague-dawley rats were injected intraperitoneally with either haloperidol (2.5 mg/kg/day), which blocks dopaminergic receptors, or saline. |
1993-04-22 |
2023-08-12 |
rat |
| G Rudolf, N Wiolan. Acute blockade of dopamine receptors with haloperidol: a retinal model to study impairments of dopaminergic transmission. European journal of pharmacology. vol 230. issue 3. 1993-04-01. PMID:8382615. |
acute blockade of dopamine receptors with haloperidol: a retinal model to study impairments of dopaminergic transmission. |
1993-04-01 |
2023-08-12 |
chicken |
| G Rudolf, N Wiolan. Acute blockade of dopamine receptors with haloperidol: a retinal model to study impairments of dopaminergic transmission. European journal of pharmacology. vol 230. issue 3. 1993-04-01. PMID:8382615. |
acute blockade of retinal dopaminergic transmission with haloperidol, a mixed antagonist, produced a dose-correlated tep voltage decrease which was rapidly reversed by intravitreal injection of dopamine. |
1993-04-01 |
2023-08-12 |
chicken |
| M C Arenas, A Parra, V M Simó. Gender differences in escape-avoidance behavior of mice after haloperidol administration. Pharmacology, biochemistry, and behavior. vol 44. issue 1. 1993-03-09. PMID:8430126. |
several possible mechanisms responsible for this greater susceptibility of males to the inhibitory effects of haloperidol on escape-avoidance learning are discussed, especially the modulating role of female hormones on dopaminergic activity. |
1993-03-09 |
2023-08-12 |
mouse |
| F Marchal, A Bairam, P Haouzi, J M Hascoet, J P Crance, P Vert, S Lahir. Dual responses of carotid chemosensory afferents to dopamine in the newborn kitten. Respiration physiology. vol 90. issue 2. 1993-03-08. PMID:1494718. |
it is concluded that the dopaminergic mechanisms are active in the carotid body of the kitten, and the observed responses to dopamine and haloperidol are qualitatively similar to those reported in the adult cat. |
1993-03-08 |
2023-08-11 |
cat |