| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J W Kebabian, D R Britton, M P DeNinno, R Perner, L Smith, P Jenner, R Schoenleber, M William. A-77636: a potent and selective dopamine D1 receptor agonist with antiparkinsonian activity in marmosets. European journal of pharmacology. vol 229. issue 2-3. 1993-03-02. PMID:1362704. |
in rats with unilateral 6-ohda (6-hydroxydopamine) lesions of the nigro-striatal dopaminergic pathway, a-77636 elicits prolonged (> 20 h) contralateral turning that is blocked by sch 23390, a d1 receptor antagonist, but not by haloperidol at doses selective for the dopamine d2 receptor. |
1993-03-02 |
2023-08-11 |
mouse |
| S Li, G Pelletie. Dopamine regulation of gonadotropin-releasing hormone (GnRH) gene expression in the female rat brain. Neuroscience letters. vol 146. issue 2. 1993-03-02. PMID:1491791. |
the effects of the dopaminergic antagonist haloperidol (hal) as well as the d2 dopamine receptor agonist bromocriptine (bro) on gonadotropin-releasing hormone (gnrh) mrna levels in intact and hypophysectomized rats were investigated by quantitative in situ hybridization. |
1993-03-02 |
2023-08-11 |
rat |
| M A Hossain, J M Masserano, N Weine. Comparative effects of electroconvulsive shock and haloperidol on in vivo tyrosine hydroxylation and tetrahydrobiopterin in the brain of rats with 6-hydroxydopamine lesions. Brain research. vol 598. issue 1-2. 1993-02-25. PMID:1486474. |
these results suggest that the nigrostriatal system, although up-regulated following 6-ohda lesions, still maintains the potential for further up-regulation of dopaminergic function in response to haloperidol and ecs treatment. |
1993-02-25 |
2023-08-11 |
rat |
| G E Ploeger, B M Spruijt, A R Cool. Effects of haloperidol on the acquisition of a spatial learning task. Physiology & behavior. vol 52. issue 5. 1993-02-18. PMID:1484855. |
the effects of systemic injections of the dopaminergic antagonist haloperidol on the acquisition of the morris water maze with either a visible or an invisible platform (nonspatial vs. spatial learning) were investigated. |
1993-02-18 |
2023-08-11 |
Not clear |
| R J Carey, E N Damianopoulo. Opponent-process theory and drug conditioning: an assessment for conditioned stimulant-induced movement. Behavioural brain research. vol 51. issue 2. 1993-01-27. PMID:1466780. |
in addition, when the animals were subsequently tested with the dopaminergic receptor antagonist, haloperidol (0.5 mg/kg), unexpectedly, contralateral rotation was enhanced in the paired group, whereas, ipsilateral rotation was suppressed in both groups. |
1993-01-27 |
2023-08-11 |
rat |
| A Słuzewska, A Choder. Antidepressant effect of carbamazepine--the role of dopaminergic and noradrenergic agents. Polish journal of pharmacology and pharmacy. vol 44. issue 3. 1993-01-22. PMID:1470559. |
two blockers of dopaminergic receptors: haloperidol (0.5 mg/kg) and sulpiride (100 mg/kg) antagonized the reduction of immobility caused by cbz. |
1993-01-22 |
2023-08-11 |
rat |
| C L Cunningham, D H Malott, S D Dickinson, F O Risinge. Haloperidol does not alter expression of ethanol-induced conditioned place preference. Behavioural brain research. vol 50. issue 1-2. 1993-01-06. PMID:1449638. |
a recent experiment (risinger et al., psychopharmacology, 107 (1992) 453-456) has shown that haloperidol does not prevent acquisition of ethanol-induced conditioned place preference, suggesting that dopaminergic mechanisms do not mediate the primary rewarding properties of ethanol. |
1993-01-06 |
2023-08-11 |
mouse |
| M Virno, A Gazzaniga, L Taverniti, J Pecori Giraldi, F De Gregori. Dopamine, dopaminergic drugs and ocular hypertension. International ophthalmology. vol 16. issue 4-5. 1992-12-23. PMID:1358853. |
such hypertensive effects could not be antagonized either by topically administered dopaminergic antagonists (sulpiride, d2-receptors antagonist, and haloperidol, non-selective dopaminergic antagonist) or by the pretreatment with the commonly used topical antiglaucomatous drugs. |
1992-12-23 |
2023-08-11 |
Not clear |
| S P Sivam, J E Kraus. Tachykinin systems in the spinal cord and basal ganglia: influence of neonatal capsaicin treatment or dopaminergic intervention on levels of peptides, substance P-encoding mRNAs, and substance P receptor mRNA. Journal of neurochemistry. vol 59. issue 6. 1992-12-22. PMID:1279124. |
in the other set of experiments, interruption of dopaminergic transmission was achieved by two methods: (a) the neurotoxin 6-hydroxydopamine was used to denervate dopaminergic neurons during the early postnatal period, and (b) haloperidol was used in adult animals to block dopaminergic transmission by receptor blockade. |
1992-12-22 |
2023-08-11 |
Not clear |
| E Carboni, G Tanda, G Di Chiar. Extracellular striatal concentrations of endogenous 3,4-dihydroxyphenylalanine in the absence of a decarboxylase inhibitor: a dynamic index of dopamine synthesis in vivo. Journal of neurochemistry. vol 59. issue 6. 1992-12-22. PMID:1431903. |
the dopaminergic antagonist haloperidol (0.2 mg/kg, s.c.) stimulated dopa output by about 60% over basal values. |
1992-12-22 |
2023-08-11 |
rat |
| J B Flexner, A C Church, L B Flexne. Long-term suppression of the development of complementary memory storage sites in mice: functional interdependence of acetylcholine and dopamine. Pharmacology, biochemistry, and behavior. vol 43. issue 2. 1992-12-22. PMID:1438499. |
we now find that this suppressive action of scopolamine can be completely nullified by haloperidol, a dopaminergic antagonist. |
1992-12-22 |
2023-08-11 |
mouse |
| I Westerhof, J T Lumeij, J A Mol, W E van den Brom, A Rijnber. In vivo studies on the effects of ovine corticotrophin-releasing hormone, arginine vasotocin, arginine vasopressin, and haloperidol on adrenocortical function in the racing pigeon (Columba livia domestica). General and comparative endocrinology. vol 88. issue 1. 1992-12-16. PMID:1426965. |
the clear response to haloperidol indicates that the hypothalamo-pituitary-adrenocortical system is under dopaminergic inhibition. |
1992-12-16 |
2023-08-11 |
pigeon |
| A Saija, P Princi, C Imperatore, R De Pasquale, G Cost. Ageing influences haloperidol-induced changes in the permeability of the blood-brain barrier in the rat. The Journal of pharmacy and pharmacology. vol 44. issue 5. 1992-12-04. PMID:1359065. |
the effect of the dopaminergic antagonist haloperidol on the permeability of the blood-brain barrier (bbb) to [14c]alpha-aminoisobutyric acid was studied in 10-12- and 28-30-week old rats. |
1992-12-04 |
2023-08-11 |
rat |
| A Saija, P Princi, C Imperatore, R De Pasquale, G Cost. Ageing influences haloperidol-induced changes in the permeability of the blood-brain barrier in the rat. The Journal of pharmacy and pharmacology. vol 44. issue 5. 1992-12-04. PMID:1359065. |
such age-associated increase in the vulnerability of the bbb when challenged with haloperidol might be related to a deterioration of the dopaminergic control of cerebrovascular permeability. |
1992-12-04 |
2023-08-11 |
rat |
| Y Tong, G Pelletie. Role of dopamine in the regulation of proopiomelanocortin (POMC) mRNA levels in the arcuate nucleus and pituitary gland of the female rat as studied by in situ hybridization. Brain research. Molecular brain research. vol 15. issue 1-2. 1992-12-02. PMID:1331668. |
the effects of the dopaminergic antagonist haloperidol (hal) as well as the d2 dopamine receptor agonist bromocriptine (bro) on proopiomelanocortin (pomc) mrna levels in the female rat arcuate nucleus and pituitary were investigated by quantitative in situ hybridization. |
1992-12-02 |
2023-08-11 |
rat |
| M L Meigna. [Delirium tremens. Recent neurophysiologic concepts and therapeutic outlook]. Cahiers d'anesthesiologie. vol 40. issue 3. 1992-10-02. PMID:1515960. |
should hallucinations become manifest, linked to dopaminergic hyperactivity, haloperidol is indicated. |
1992-10-02 |
2023-08-11 |
Not clear |
| C W Schindler, J W Zheng, S R Tella, S R Goldber. Pharmacological mechanisms in the cardiovascular effects of methamphetamine in conscious squirrel monkeys. Pharmacology, biochemistry, and behavior. vol 42. issue 4. 1992-09-25. PMID:1325059. |
the dopaminergic antagonists sch 23390 and haloperidol antagonized some of the cardiovascular effects of methamphetamine. |
1992-09-25 |
2023-08-11 |
monkey |
| M Laruelle, G E Jaskiw, B K Lipska, B Kolachana, M F Casanova, J E Kleinman, D R Weinberge. D1 and D2 receptor modulation in rat striatum and nucleus accumbens after subchronic and chronic haloperidol treatment. Brain research. vol 575. issue 1. 1992-09-24. PMID:1387032. |
nevertheless, the effects of chronic (3-12 months) haloperidol administration on the dopaminergic transmission in the nucleus accumbens of rodents remains poorly understood. |
1992-09-24 |
2023-08-11 |
rat |
| S K Johnson, G C Wagner, H Fische. Neurochemical and motor effects of high dose haloperidol treatment: exacerbation by tryptophan supplementation. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). vol 200. issue 4. 1992-09-18. PMID:1380718. |
in experiment 1, this high dose of haloperidol caused dramatic increases in striatal dopaminergic and serotonergic turnover that only returned to control levels 100 hr after injection. |
1992-09-18 |
2023-08-11 |
rat |
| W Löscher, G Fredo. Effects of pharmacological manipulation of dopaminergic and cholinergic neurotransmission in genetically dystonic hamsters. European journal of pharmacology. vol 213. issue 1. 1992-09-14. PMID:1323471. |
no differences were observed between dystonic and non-dystonic hamsters with respect to extent and duration of stereotypies induced by dopaminergic and cholinergic drugs or hypolocomotion and catalepsy produced by haloperidol. |
1992-09-14 |
2023-08-11 |
Not clear |