| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G E Ploeger, B M Spruijt, A R Cool. Spatial localization in the Morris water maze in rats: acquisition is affected by intra-accumbens injections of the dopaminergic antagonist haloperidol. Behavioral neuroscience. vol 108. issue 5. 1995-02-23. PMID:7826515. |
spatial localization in the morris water maze in rats: acquisition is affected by intra-accumbens injections of the dopaminergic antagonist haloperidol. |
1995-02-23 |
2023-08-12 |
rat |
| Y Haskel, M Hanan. Inhibition of gastrointestinal motility by MPTP via adrenergic and dopaminergic mechanisms. Digestive diseases and sciences. vol 39. issue 11. 1994-12-13. PMID:7956604. |
the dopaminergic blocker haloperidol also partly reversed the effects of mptp. |
1994-12-13 |
2023-08-12 |
mouse |
| C A Fornal, W J Litto, C W Metzler, F Marrosu, K Tada, B L Jacob. Single-unit responses of serotonergic dorsal raphe neurons to 5-HT1A agonist and antagonist drug administration in behaving cats. The Journal of pharmacology and experimental therapeutics. vol 270. issue 3. 1994-11-07. PMID:7932189. |
these effects of spiperone cannot be attributed to its dopaminergic d2 or serotonergic 5-ht2 antagonist properties, because administration of haloperidol and ritanserin produced no increase in neuronal activity and did not block the action of 8-oh-dpat. |
1994-11-07 |
2023-08-12 |
Not clear |
| D A Dartt, P E Rose, D M Dicker, L V Ronco, R R Hodge. Alpha 1-adrenergic agonist-stimulated protein secretion in rat exorbital lacrimal gland acini. Experimental eye research. vol 58. issue 4. 1994-10-21. PMID:7925679. |
the alpha 2-adrenergic antagonist yohimbine, the beta-adrenergic antagonist timolol, and the dopaminergic antagonist haloperidol also inhibited phenylephrine-induced secretion but were 100-fold less potent than prazosin. |
1994-10-21 |
2023-08-12 |
rat |
| R Li, D M Chuang, R J Wyatt, D G Kirc. Effect of chronic haloperidol treatment on dopamine-induced inositol phosphate formation in rat brain slices. Neurochemical research. vol 19. issue 6. 1994-09-20. PMID:8065524. |
the effects of chronic haloperidol administration on the accumulation of inositol phosphates were examined in rat brain slices pre-labeled with [3h]myo-inositol and incubated with various dopaminergic drugs. |
1994-09-20 |
2023-08-12 |
rat |
| D I Schuster, G K Ehrlich, R B Murph. Purification and partial amino acid sequence of a 28 kDa cyclophilin-like component of the rat liver sigma receptor. Life sciences. vol 55. issue 8. 1994-08-30. PMID:8046989. |
the sigma (sigma) receptor, a putative non-opioid receptor site which has been suggested to function as a neuromodulator of dopaminergic and nmda systems, and is found in brain, liver and many other tissues, has been purified > 560-fold from a detergent-solubilized rat liver membrane preparation by affinity chromatography, using an affinity matrix prepared from an oximino derivative of haloperidol. |
1994-08-30 |
2023-08-12 |
rat |
| J D Brioni, D J Kim, A B O'Neill, J E Williams, M W Decke. Clozapine attenuates the discriminative stimulus properties of (-)-nicotine. Brain research. vol 643. issue 1-2. 1994-08-12. PMID:8032906. |
the effect of neuronal nicotinic acetylcholine receptor (nachr) agonists and antagonists were verified, and the participation of dopaminergic receptors subtypes in the expression of the (-)-nicotine cue was investigated with cis-flupentixol (d1-d2 antagonist), haloperidol (d2 antagonist) and clozapine (d4 antagonist). |
1994-08-12 |
2023-08-12 |
rat |
| O Stork, T Hashimoto, K Obat. Increase of tyrosine hydroxylase and its mRNA in the rat substantia nigra pars reticulata by diazepam and picrotoxin. Neuroscience research. vol 19. issue 1. 1994-07-20. PMID:7911985. |
these results suggest that haloperidol and diazepam regulate th gene expression in the snr commonly by depressing dopaminergic transmission, and that diazepam activates th expression in a group of snr neurons which express this gene after haloperidol treatment. |
1994-07-20 |
2023-08-12 |
rat |
| M A Cheĭdo, G V Idov. [The participation of the delta opioid receptors in immunomodulation]. Fiziologicheskii zhurnal imeni I.M. Sechenova. vol 79. issue 12. 1994-05-26. PMID:8162115. |
the immunostimulation was shown to be realised via the thymus and prevented by a preliminary haloperidol blockade of the d-2 dopaminergic receptors. |
1994-05-26 |
2023-08-12 |
mouse |
| U D Behrens, R H Douglas, H J Wagne. Gonadotropin-releasing hormone, a neuropeptide of efferent projections to the teleost retina induces light-adaptive spinule formation on horizontal cell dendrites in dark-adapted preparations kept in vitro. Neuroscience letters. vol 164. issue 1-2. 1994-05-09. PMID:8152616. |
this effect was blocked by addition of haloperidol to the incubation medium suggesting that gnrh acts via stimulation of the dopaminergic interplexiform cells. |
1994-05-09 |
2023-08-12 |
Not clear |
| N Bäck, S Soinil. Regulation of secretory granule formation in chronically hypersecretory melanotrophs in the rat pituitary. Cell and tissue research. vol 275. issue 2. 1994-03-28. PMID:8111840. |
hypersecretion was induced by treatment with the dopamine antagonist haloperidol (1.5 mg/kg daily for 7 days), which releases the normal neural dopaminergic inhibition of secretion from the melanotroph. |
1994-03-28 |
2023-08-12 |
rat |
| A Di Giannuario, S Pieretti, M Luzi, A Loizz. Subchronic treatment with fragments of beta-endorphin prevents electroencephalographic seizures and behavioral alterations induced by centrally administered beta-endorphin in the rabbit. The Journal of pharmacology and experimental therapeutics. vol 268. issue 2. 1994-03-28. PMID:8113960. |
the effects of some beta-endorphin fragments with neuroleptic-like properties, i.e., tau-endorphin, des-tyr1-tau-endorphin (dt tau e), desenkephalin-tau-endorphin (de tau e), in comparison with the dopaminergic antagonist haloperidol,- were studied on the eeg and behavioral alterations induced by beta-endorphin in the rabbit. |
1994-03-28 |
2023-08-12 |
rabbit |
| A Di Giannuario, S Pieretti, M Luzi, A Loizz. Subchronic treatment with fragments of beta-endorphin prevents electroencephalographic seizures and behavioral alterations induced by centrally administered beta-endorphin in the rabbit. The Journal of pharmacology and experimental therapeutics. vol 268. issue 2. 1994-03-28. PMID:8113960. |
our results show that dt tau e and de tau e, which are devoid of opioid activity, exert a strong antagonism on ictal seizures as well as on other eeg alterations and behavioral alterations induced by beta-endorphin, and suggest that the antagonism shown by these drugs and by haloperidol on the eeg effects induced by beta-endorphin are exerted at least in part through an indirect action, i.e., an interaction with the dopaminergic system. |
1994-03-28 |
2023-08-12 |
rabbit |
| C W Shults, R T Matthews, C A Altar, L R Hill, P J Langlai. A single intramesencephalic injection of brain-derived neurotrophic factor induces persistent rotational asymmetry in rats. Experimental neurology. vol 125. issue 2. 1994-03-23. PMID:8313937. |
the amphetamine-induced contraversive rotation could be blocked by administration of the dopaminergic antagonist haloperidol. |
1994-03-23 |
2023-08-12 |
rat |
| A C Cherñavsky, A V Valerani, J A Burdma. Haloperidol and oestrogens induce c-myc and c-fos expression in the anterior pituitary gland of the rat. Neurological research. vol 15. issue 5. 1994-03-10. PMID:7905609. |
administration of the dopaminergic antagonist haloperidol did not change the levels of protooncogenes mrna. |
1994-03-10 |
2023-08-12 |
rat |
| H Rollema, M Skolnik, J D'Engelbronner, K Igarashi, E Usuki, N Castagnol. MPP(+)-like neurotoxicity of a pyridinium metabolite derived from haloperidol: in vivo microdialysis and in vitro mitochondrial studies. The Journal of pharmacology and experimental therapeutics. vol 268. issue 1. 1994-03-10. PMID:8301579. |
intracerebral (intrastriatal, intranigral and intracortical) microdialysis studies were conducted in conscious rats to investigate the comparative dopaminergic and serotonergic neurotoxic potential of the pyridinium metabolite 4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]pyridinium (hpp+), derived from the extensively used neuroleptic agent haloperidol and 1-methyl-4-phenylpyridinium (mpp+), the pyridinium metabolite derived from the parkinsonian inducing agent 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp). |
1994-03-10 |
2023-08-12 |
rat |
| R Gaggi, R Cont, A M Giann. Comparison among the effects of nifedipine, nimodipine and nisoldipine on the brain biogenic amines of normal or haloperidol treated rats. General pharmacology. vol 24. issue 5. 1994-02-01. PMID:8270166. |
the small changes induced by the drugs on normal rats were markedly increased in the haloperidol treated rats, clearly showing an inhibition of dopaminergic systems. |
1994-02-01 |
2023-08-12 |
rat |
| B H Schmidt, F Chaoulof. Chronic treatment with an anxiolytic dose of the 5-HT1A agonist ipsapirone does not alter ipsapirone acute neuroendocrine effects. Psychoneuroendocrinology. vol 18. issue 7. 1994-01-27. PMID:7903466. |
moreover, ipsapirone pretreatment did not affect the increase in plasma prolactin levels elicited by the dopaminergic receptor antagonist haloperidol. |
1994-01-27 |
2023-08-12 |
rat |
| K K Pant, C Nat. Dopaminergic involvement in the effects of piracetam on foot shock induced aggression in mice. The Indian journal of medical research. vol 98. 1993-12-02. PMID:7901159. |
dopaminergic receptor blocker haloperidol (0.5; 0.25 and 0.12 mg/kg, ip) and pimozide (1.0 mg/kg, ip) produced inhibition of the aggressive behaviour. |
1993-12-02 |
2023-08-12 |
mouse |
| T P Shevchenko, B A Tolpyshev, L N Zban\. [The behavioral and neurochemical changes in rats caused by the subchronic administration of haloperidol]. Eksperimental'naia i klinicheskaia farmakologiia. vol 56. issue 3. 1993-12-01. PMID:8219980. |
rat experiments showed that subchronic haloperidol enhanced or perverted motor asymmetry appearing in response to apomorphine, resulted in imbalance between the dopaminergic and serotoninergic systems and increased norepinephrine levels. |
1993-12-01 |
2023-08-12 |
rat |