| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T A Jenkins, S Y Chai, F A Mendelsoh. Upregulation of angiotensin II AT1 receptors in the mouse nucleus accumbens by chronic haloperidol treatment. Brain research. vol 748. issue 1-2. 1997-05-27. PMID:9067454. |
considering our previous anatomical and functional studies demonstrating an interaction between brain angiotensin ii and dopaminergic systems, the effect of chronic treatment with the dopamine antagonist, haloperidol, on at1 and at2 receptor levels was investigated in the mouse brain. |
1997-05-27 |
2023-08-12 |
mouse |
| J Fan. Hyperactive behavioural effects induced by intranigral infusion of a pyridinium metabolite of haloperidol in rats. Canadian journal of physiology and pharmacology. vol 74. issue 12. 1997-05-08. PMID:9047047. |
this apparent dopamine agonist effect of hp+ may be relevant to some of the clinical side effects of haloperidol such as acute dystonia and chronic tardive dyskinesia, which have been proposed to be the result of dopaminergic hyperactivity. |
1997-05-08 |
2023-08-12 |
rat |
| S K Hore, V K Dumka, D Kumar, H C Tripathi, S K Tanda. Central noradrenergic & dopaminergic modulation of brewer's yeast-induced inflammation & nociception in rats. The Indian journal of medical research. vol 105. 1997-04-29. PMID:9055502. |
conversely, the beta-adrenoceptor blocker, propranolol, catecholaminergic neuron degenerator, 6-hydroxydopamine (6-ohda), dopaminergic antagonist, haloperidol and dopamine synthesis inhibitor, alpha-methyl para tyrosine (ampt) augmented paw oedema. |
1997-04-29 |
2023-08-12 |
rat |
| G Catalano, M C Catalano, W Taylo. Acute risperidone overdose. Clinical neuropharmacology. vol 20. issue 1. 1997-04-28. PMID:9037577. |
it is different from the conventional neuroleptics, such as haloperidol, as it has both serotinergic and dopaminergic activity. |
1997-04-28 |
2023-08-12 |
Not clear |
| K Antoniou, A Vamvakides, Z Papadopoulou-Daifotis, I Zervou, D Varono. The neurochemical effects on striatal dopamine turnover rate of N-stearyl dopamine after acute administration in rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 20. issue 1. 1997-04-11. PMID:8861181. |
it is worth noting that this behavioural response was partially antagonized by dopaminergic antagonists, such as haloperidol and sulpiride, administered at doses that block da autoreceptors. |
1997-04-11 |
2023-08-12 |
mouse |
| A Yeşilada, N Gökhan, I Ozer, K Vural, K Ero. 5-methyl-8-N-substituted-thiocarbamoyl-7,8-diazabicyclo[4.3.0] non-6-enes: evaluation as BSAO inhibitors and pharmacological activity screening. Farmaco (Societa chimica italiana : 1989). vol 51. issue 12. 1997-04-10. PMID:9050209. |
while the other group was inactive as antidepressant effect, these compounds have shown diastereoselective antitremor activity by inhibiting the tremors induced by oxotremorin in mice pretreated with dopaminergic antagonist haloperidol. |
1997-04-10 |
2023-08-12 |
mouse |
| b' P Sikiri\\xc4\\x87, B Mazul, S Seiwerth, Z Grabarevi\\xc4\\x87, R Rucman, M Petek, V Jagi\\xc4\\x87, B Turkovi\\xc4\\x87, I Rotkvi\\xc4\\x87, S Mise, I Zorici\\xc4\\x87, L Jurina, P Konjevoda, M Hanzevacki, M Gjurasin, J Separovi\\xc4\\x87, D Ljubanovi\\xc4\\x87, B Artukovi\\xc4\\x87, M Bratuli\\xc4\\x87, M Tisljar, P Mikli\\xc4\\x87, J Sumajstorci\\xc4\\x8. Pentadecapeptide BPC 157 interactions with adrenergic and dopaminergic systems in mucosal protection in stress. Digestive diseases and sciences. vol 42. issue 3. 1997-04-09. PMID:9073154.' |
animals were pretreated (1 hr before stress) with saline (controls) or bpc 157 (dissolved in saline) (10 microg or 10 ng/kg body wt intraperitoneally or intragastrically) applied either alone to establish basal conditions or, when manipulating the adrenergic or dopaminergic system, a simultaneous administration was carried out with various agents with specific effects on adrenergic or dopaminergic receptors [given in milligrams per kilogram intraperitoneally except for atenolol, which was given subcutaneously] phentolamine (10.0), prazosin (0.5), yohimbine (5.0), clonidine (0.1) (alpha-adrenergic domain), propranolol (1.0), atenolol (20.0) (beta-adrenergic domain), domperidone (5.0), and haloperidol (5.0) (peripheral/central dopamine system). |
1997-04-09 |
2023-08-12 |
Not clear |
| B Vitiello, A Martin, J Hill, C Mack, S Molchan, R Martinez, D L Murphy, T Sunderlan. Cognitive and behavioral effects of cholinergic, dopaminergic, and serotonergic blockade in humans. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 16. issue 1. 1997-03-28. PMID:8981385. |
the data indicate that scopolamine and haloperidol can independently and selectively affect cognition and that at the doses tested in this study no synergistic exacerbation of cognitive functioning was found when cholinergic blockage was coupled with dopaminergic or serotonergic blockade. |
1997-03-28 |
2023-08-12 |
human |
| L M Gershteĭn, E L Dovedova, M T Dobrynina, A V Sergutina, V I Rakhmanov. [The morphochemical characteristics of the reaction of the motor structures of the brain to hyper- and hypofunction of the dopaminergic system]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 96. issue 6. 1997-03-26. PMID:9072895. |
the study was performed during chronic l-dopa and haloperidol administration that is under the conditions of hyper- and hypofunction of dopaminergic system. |
1997-03-26 |
2023-08-12 |
rat |
| T A Kosten, J L DeCaprio, E J Nestle. Long-term haloperidol administration enhances and short-term administration attenuates the behavioral effects of cocaine in a place conditioning procedure. Psychopharmacology. vol 128. issue 3. 1997-03-24. PMID:8972550. |
place conditioning to moderate doses of cocaine (10-15 mg/kg) was attenuated significantly, consistent with the dopaminergic actions of haloperidol and cocaine. |
1997-03-24 |
2023-08-12 |
rat |
| G McAllister, M R Knowles, S M Ward-Booth, H A Sinclair, S Patel, R Marwood, F Emms, S Patel, A Smith, G R Seabroo. Functional coupling of human D2, D3, and D4 dopamine receptors in HEK293 cells. Journal of receptor and signal transduction research. vol 15. issue 1-4. 1997-03-12. PMID:8903944. |
this activation was prevented by pre-incubation of the cells expressing these receptors with the dopaminergic antagonist haloperidol. |
1997-03-12 |
2023-08-12 |
human |
| P Stathis, K Antoniou, Z Papadopoulou-Daifotis, M N Rimikis, D Varono. Risperidone: a novel antipsychotic with many "atypical" properties? Psychopharmacology. vol 127. issue 3. 1997-03-11. PMID:8912395. |
the acute and chronic administration effects of risperidone (ris), a mixed 5ht2/d2 receptor antagonist, versus haloperidol (hal) on dopaminergic and serotoninergic activity were investigated in the rat prefrontal cortex (pfc), and the whole striatum (str) as well as separately, in dorsal striatum (strd) and nucleus accumbens (acb). |
1997-03-11 |
2023-08-12 |
rat |
| B Karolewicz, L Antkiewicz-Michaluk, J Michaluk, J Vetulan. Different effects of chronic administration of haloperidol and pimozide on dopamine metabolism in the rat brain. European journal of pharmacology. vol 313. issue 3. 1997-03-07. PMID:8911913. |
our results suggest that in contrast to haloperidol, pimozide is not able to produce adaptive changes leading to supersensitivity of the dopaminergic system. |
1997-03-07 |
2023-08-12 |
rat |
| D A Sakharov, E E Voronezhskaya, L Nezlin, M W Baker, K Elekes, R P Crol. Tyrosine hydroxylase-negative, dopaminergic neurons are targets for transmitter-depleting action of haloperidol in the snail brain. Cellular and molecular neurobiology. vol 16. issue 4. 1997-02-05. PMID:8879748. |
tyrosine hydroxylase-negative, dopaminergic neurons are targets for transmitter-depleting action of haloperidol in the snail brain. |
1997-02-05 |
2023-08-12 |
Not clear |
| D A Sakharov, E E Voronezhskaya, L Nezlin, M W Baker, K Elekes, R P Crol. Tyrosine hydroxylase-negative, dopaminergic neurons are targets for transmitter-depleting action of haloperidol in the snail brain. Cellular and molecular neurobiology. vol 16. issue 4. 1997-02-05. PMID:8879748. |
the results thus demonstrate a depleting action of low micromolar doses of chronic haloperidol on specific subsets of dopaminergic neurons and a novel preparation for studying catecholaminergic mechanisms operating across the animal kingdom. |
1997-02-05 |
2023-08-12 |
Not clear |
| M Nomot. [Recent progress in development of psychotropic drugs (3)--Antiparkinsonian agents applied in the treatment of Parkinson's disease or are under investigation for patients or model animals]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 16. issue 4. 1997-01-21. PMID:8905800. |
on the other hand, an electrical focal lesion in the brain, neurotoxin to dopaminergic neurons such as 6-hydroxydopamine (6-ohda) or i-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (mptp), cholinomimetic tremorogenic agents such as oxotremorine or tremorine, monoamine depleting agents such as reserpine or tetrabenazine, or dopamine receptor antagonists such as haloperidol are applied to render animal parkinsonism. |
1997-01-21 |
2023-08-12 |
Not clear |
| M R Kilbourn, K A Frey, T Vander Borght, P S Sherma. Effects of dopaminergic drug treatments on in vivo radioligand binding to brain vesicular monoamine transporters. Nuclear medicine and biology. vol 23. issue 4. 1997-01-16. PMID:8832701. |
in contrast, radiotracer distributions remained unchanged after treatments with other dopaminergic drugs, whether given by single injection (haloperidol, 1 mg/kg i.p., pargyline 80 mg/kg), repeatedly (pargyline, 80 mg/kg s.c., 14 days), or by continuous infusion (deprenyl, 10 mg/kg/day, 5 days; l-dopa methyl ester 100 mg/kg/day, 5 days). |
1997-01-16 |
2023-08-12 |
rat |
| A Dalia, N J Uretsky, L J Wallac. Induction of locomotor activity by the glutamate antagonist DNQX injected into the ventral tegmental area. Brain research. vol 728. issue 2. 1997-01-15. PMID:8864484. |
however, the locomotor stimulation produced by dnqx was markedly attenuated following blockade of dopaminergic receptors by haloperidol (0.5 mg/kg, s.c.) or following dopamine depletion induced by reserpine plus alpha-methyl-para-tyrosine pretreatment. |
1997-01-15 |
2023-08-12 |
Not clear |
| E D Levin, D Torr. Acute and chronic nicotine effects on working memory in aged rats. Psychopharmacology. vol 123. issue 1. 1996-12-03. PMID:8741959. |
after a 2 week withdrawal period the remaining rats underwent a series of acute drug challenges with nicotinic and muscarinic agonists and antagonists as well as the dopaminergic antagonist haloperidol. |
1996-12-03 |
2023-08-12 |
rat |
| M F Egan, S J Chrapusta, F Karoum, R J Wyat. The effects of acute and chronic haloperidol treatment on dopamine release mediated by the medial forebrain bundle in the striatum and nucleus accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 14. issue 3. 1996-12-03. PMID:8866705. |
these data suggest that dopaminergic neuronal impulse flow modulates similar amounts of total transmitter release after both acute and chronic haloperidol treatment. |
1996-12-03 |
2023-08-12 |
rat |