| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M A Vital, J C Flório, R Frussa-Filho, R De Lucia, S Tufik, J Palermo-Net. Effects of haloperidol and GM1 ganglioside treatment on striatal D2 receptor binding and dopamine turnover. Life sciences. vol 62. issue 13. 1998-04-06. PMID:9519797. |
previous studies have shown that whereas exogenous gm1 ganglioside co-administration leads to an increase of haloperidol-induced behavioral supersensitivity, gm1 significantly attenuates the behavioral parameters of dopaminergic supersensitivity when administered after abrupt haloperidol withdrawal. |
1998-04-06 |
2023-08-12 |
rat |
| A Zalewska, K Wiśniewsk. Behavioral activity of 1S,3R-ACPD, an agonist of metabotropic glutamate receptors. Polish journal of pharmacology. vol 49. issue 4. 1998-03-02. PMID:9437767. |
doses of 100 and 200 nmole significantly decreased apomorphine-induced stereotypy, and at a dose 200 nmole significantly diminished catalepsy caused by haloperidol, two behavioral symptoms controlled mainly by central dopaminergic system. |
1998-03-02 |
2023-08-12 |
rat |
| U Ziemann, F Tergau, D Bruns, J Baudewig, W Paulu. Changes in human motor cortex excitability induced by dopaminergic and anti-dopaminergic drugs. Electroencephalography and clinical neurophysiology. vol 105. issue 6. 1998-02-05. PMID:9448644. |
transcranial magnetic stimulation was used to probe the acute effect of a single oral dose of various dopaminergic (levodopa, selegiline, bromocriptine) and antidopaminergic drugs (sulpiride, haloperidol) on motor cortex excitability in healthy volunteers. |
1998-02-05 |
2023-08-12 |
human |
| J A Gray, P M Moran, G Grigoryan, S L Peters, A M Young, M H Josep. Latent inhibition: the nucleus accumbens connection revisited. Behavioural brain research. vol 88. issue 1. 1998-02-04. PMID:9401705. |
new evidence in support of this hypothesis is presented or reviewed here, showing that: (1) intra-accumbens injection of haloperidol at the time of conditioning potentiates li; (2) destruction of dopaminergic terminals in the nucleus accumbens potentiates li; (3) intra-accumbens haloperidol reverses the blockade of li caused by systemic nicotine; (4) intra-accumbens haloperidol reverses the blockade of li caused by systemic amphetamine; (5) after a single systemic injection of amphetamine (insufficient on its own to block li), a subsequent intra-accumbens injection of amphetamine at the time of conditioning blocks li; and (6) intra-accumbens (like systemic) amphetamine administered 15 min before conditioning, without prior systemic amphetamine, failed to block li. |
1998-02-04 |
2023-08-12 |
human |
| S A Yasin, M L Forslin. Mechanisms of melatonin inhibition of neurohypophysial hormone release from the rat hypothalamus in vitro. Brain research bulletin. vol 45. issue 1. 1998-02-04. PMID:9434202. |
the agents employed were atropine, a muscarinic cholinergic antagonist; mecamylamine, a nicotinic cholinergic antagonist; atenolol, a beta-adrenergic antagonist; phentolamine, a nonselective alpha-adrenergic antagonist; prazosin, a selective alpha-adrenergic antagonist; haloperidol, a dopaminergic antagonist; naloxone, an opioid antagonist; and ibuprofen, a cyclooxygenase inhibitor. |
1998-02-04 |
2023-08-12 |
rat |
| W Blenau, J Erber, A Bauman. Characterization of a dopamine D1 receptor from Apis mellifera: cloning, functional expression, pharmacology, and mRNA localization in the brain. Journal of neurochemistry. vol 70. issue 1. 1998-02-02. PMID:9422342. |
dopaminergic receptor ligands compete for this high-affinity binding, with the following order of potency: r(+)-lisuride > chlorpromazine = cis(z)-flupentixol > dopamine > s(+)-butaclamol > r(+)-sch 23390 > haloperidol. |
1998-02-02 |
2023-08-12 |
Not clear |
| A Hoffman, M Afargan, J Backon, I Perlstei. The anticonvulsant effect of deprenyl on pentylenetetrazol-induced seizures in Lewis rats. The International journal of neuroscience. vol 90. issue 3-4. 1998-01-26. PMID:9352429. |
the data suggests that the mechanism of this effect is not associated with the dopaminergic activity of deprenyl since pretreatment with both bromocriptine (a dopamine d2 agonist) and haloperidol (dopamine antagonist) did not affect the seizure threshold, whereas levodopa caused a proconvulsant effect. |
1998-01-26 |
2023-08-12 |
rat |
| T H Rammsaye. Effects of body core temperature and brain dopamine activity on timing processes in humans. Biological psychology. vol 46. issue 2. 1997-12-02. PMID:9288412. |
for temporal discrimination of intervals in the range of seconds, a significant interaction between ambient temperature and haloperidol could be established (p < 0.05) indicating that haloperidol caused a significant performance decrement only in subjects exposed to an ambient temperature of 28 degrees c but not in those exposed to 52 degrees c. the overall pattern of results suggests that temporal processing of intervals in the range of milliseconds can be considered a function of dopaminergic activity in the basal ganglia while temporal processing of longer intervals appears to be cognitively mediated. |
1997-12-02 |
2023-08-12 |
human |
| M E Bardgett, S L Salaris, J L Jackson, J Harding, J G Csernansk. The effects of kainic acid lesions on dopaminergic responses to haloperidol and clozapine. Psychopharmacology. vol 133. issue 2. 1997-11-20. PMID:9342780. |
the effects of kainic acid lesions on dopaminergic responses to haloperidol and clozapine. |
1997-11-20 |
2023-08-12 |
rat |
| M E Bardgett, S L Salaris, J L Jackson, J Harding, J G Csernansk. The effects of kainic acid lesions on dopaminergic responses to haloperidol and clozapine. Psychopharmacology. vol 133. issue 2. 1997-11-20. PMID:9342780. |
these results indicate that dopaminergic responses to haloperidol may be diminished by limbic-cortical neuropathology, while such pathology does not significantly alter dopaminergic responses to clozapine. |
1997-11-20 |
2023-08-12 |
rat |
| J Fang, P H Y. Effects of a quaternary pyridinium metabolite of haloperidol (HP+) on the viability and catecholamine levels of cultured PC12 cells. Canadian journal of physiology and pharmacology. vol 75. issue 8. 1997-11-20. PMID:9360014. |
hp+ is toxic towards dopaminergic neurons and was proposed to be associated with some of the extrapyramidal side effects of haloperidol. |
1997-11-20 |
2023-08-12 |
rat |
| V Kumari, P J Corr, O F Mulligan, P A Cotter, S A Checkley, J A Gra. Effects of acute administration of d-amphetamine and haloperidol on procedural learning in man. Psychopharmacology. vol 129. issue 3. 1997-11-19. PMID:9084066. |
the results showed: (1) d-amphetamine facilitated response speed, whereas haloperidol inhibited it, in comparison to placebo; (2) the linear increase in procedural learning corresponded with pharmacological manipulation of degree of dopaminergic activity, i.e. |
1997-11-19 |
2023-08-12 |
human |
| S W Tang, D M Helmeste, H Fang, M Li, R Vu, W Bunney, S Potkin, E G Jone. Differential labeling of dopamine and sigma sites by [3H]nemonapride and [3H]raclopride in postmortem human brains. Brain research. vol 765. issue 1. 1997-11-06. PMID:9310388. |
haloperidol defined a combination of sites, which were approximately the sum of the dopaminergic and sigma components defined by sulpiride and ppap, respectively. |
1997-11-06 |
2023-08-12 |
human |
| M F Piercey, D K Hyslop, W E Hoffman. Excitation of type II anterior caudate neurons by stimulation of dopamine D3 receptors. Brain research. vol 762. issue 1-2. 1997-10-01. PMID:9262154. |
the d3-preferring antagonist (+)-aj76 was weaker than haloperidol, a d2-preferring antagonist, in reversing the effects of amphetamine on firing rates in dopaminergic neurons in both the snpc and the cn. |
1997-10-01 |
2023-08-12 |
Not clear |
| M Rodríguez-Arias, J Miñarro, V M Simó. Interaction of morphine and haloperidol on agonistic and motor behaviors of male mice. Pharmacology, biochemistry, and behavior. vol 58. issue 1. 1997-09-30. PMID:9264084. |
to further clarify the interaction between opioid and dopaminergic systems, the effects of simultaneous administration of morphine hydrochloride (1.25 or 2.5 mg/kg) and haloperidol (0.1 mg/kg) on aggressive behavior of male mice were explored. |
1997-09-30 |
2023-08-12 |
mouse |
| A Newman-Tancredi, V Audinot-Bouchez, A Gobert, M J Milla. Noradrenaline and adrenaline are high affinity agonists at dopamine D4 receptors. European journal of pharmacology. vol 319. issue 2-3. 1997-09-22. PMID:9042615. |
the dopamine d4 receptor-selective ligand, 3-(4-[4-chlorophenyl]piperazin-1-yl)methyl-1h-pyrrolo[2,3b]-pyridi ne (l 745,870) and the dopaminergic antagonists, spiperone, haloperidol and clozapine, inhibited noradrenaline-stimulated [35s]gtp gamma s binding whereas alpha 1-, alpha 2- and beta-adrenoceptor antagonists did not. |
1997-09-22 |
2023-08-12 |
Not clear |
| M D Freedma. Neuroleptic malignant syndrome and acute myocardial infarction: case report and review. Maryland medical journal (Baltimore, Md. : 1985). vol 46. issue 7. 1997-09-17. PMID:9260471. |
the neuroleptic malignant syndrome (nms) is a potentially life threatening reaction usually observed following administration of dopaminergic antagonists (neuroleptic medications, e.g., phenothiazines, thioxanthenes, and haloperidol). |
1997-09-17 |
2023-08-12 |
Not clear |
| V M Mansour, I J Clarke, A I Smit. The characterization, localization and regulation of endothelin in ovine pars intermedia. Regulatory peptides. vol 70. issue 1. 1997-09-16. PMID:9250582. |
normal sheep were treated chronically with haloperidol or bromocriptine to investigate the possibility of dopaminergic regulation of et in the il. |
1997-09-16 |
2023-08-12 |
Not clear |
| S Giacomelli, L Braghiroli, A Ponzianelli, D W Koppenaal, G De Fe. A sensitive assay for studying dopaminergic activity in cultures of rat pituitary cells. The Journal of pharmacy and pharmacology. vol 49. issue 3. 1997-08-27. PMID:9231354. |
d2 agonistic activity of bromocriptine could be observed at a concentration as low as 10(-15) m, the antagonistic activity of haloperidol at 10(-16) m. the assay also proved reproducible and simple enough for routine screening of dopaminergic activity. |
1997-08-27 |
2023-08-12 |
rat |
| E M Nakamura-Palacio. Effects of haloperidol on behavioral responses induced by electrical stimulation of medial prefrontal cortex. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 29. issue 10. 1997-08-14. PMID:9181108. |
these results show that haloperidol, a dopaminergic antagonist and antipsychotic agent, interfered significantly with the expression of behaviors induced by electrical stimulation of the left medial pfc, suggesting that the induction of these behaviors may involve the dopaminergic neurotransmission. |
1997-08-14 |
2023-08-12 |
rat |