| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| V D Petkov, B Petkov. Behavioral changes as a result of dotarizine or flunarizine influence on dopaminergic neurotransmission in the striatum. Acta physiologica et pharmacologica Bulgarica. vol 23. issue 1. 1999-06-15. PMID:10347616. |
the flunarizine-induced changes in the behavioral effects of apomorphine, amphetamine and haloperidol suggest the decrease of striatal dopaminergic neurotransmission, whereby the risk of occurrence of extrapyramidal side effects of the drug when used in clinical practice. |
1999-06-15 |
2023-08-12 |
rat |
| O Yokoyama, M Yoshiyama, M Namiki, W C de Groa. Glutamatergic and dopaminergic contributions to rat bladder hyperactivity after cerebral artery occlusion. The American journal of physiology. vol 276. issue 4. 1999-05-13. PMID:10198370. |
the contribution of glutamatergic and dopaminergic mechanisms to bladder hyperactivity after left middle cerebral artery occlusion was evaluated by determining the effects of intravenous cumulative doses of an n-methyl-d-aspartate (nmda) glutamatergic antagonist (mk-801) and d1-selective (sch-23390), d2-selective (sulpiride), or nonselective (haloperidol) dopaminergic antagonists on bladder activity in sham-operated (so) and cerebral-infarcted (ci) rats. |
1999-05-13 |
2023-08-12 |
rat |
| D M Fass, K Takimoto, R E Mains, E S Levita. Tonic dopamine inhibition of L-type Ca2+ channel activity reduces alpha1D Ca2+ channel gene expression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 9. 1999-05-07. PMID:10212294. |
experiments involving in vivo and in vitro treatments with the dopaminergic drugs haloperidol, bromocriptine, and quinpirole show that d2 receptors persistently decrease alpha1d l-type ca2+ channel mrna and l-type ca2+ channel current without altering channel gating properties. |
1999-05-07 |
2023-08-12 |
Not clear |
| T L Lee, C T Hsu, S T Yen, C W Lai, J T Chen. Activation of beta3-adrenoceptors by exogenous dopamine to lower glucose uptake into rat adipocytes. Journal of the autonomic nervous system. vol 74. issue 2-3. 1999-04-07. PMID:9915622. |
dopamine induced a concentration-dependent decrease of 2-dg uptake into adipocytes in a manner which was not modified by haloperidol at concentrations sufficient to block dopaminergic receptors. |
1999-04-07 |
2023-08-12 |
rat |
| E E Hucke, P E Cruz-Casallas, J C Florio, L F Felici. Reproductive experience reduces striatal dopaminergic responses in freely moving female rats. Neuroreport. vol 9. issue 16. 1999-02-26. PMID:9858365. |
in addition, a distinct striatal dopaminergic response to haloperidol was observed in primiparous as compared to nulliparous ovariectomized rats. |
1999-02-26 |
2023-08-12 |
rat |
| S T Yen, M H Li, C T Hsu, T L Lee, J T Chen. Stimulatory effect of octopamine on beta 3-adrenoceptors to lower the uptake of [14C]-deoxy-D-glucose into rat adipocytes in vitro. Journal of autonomic pharmacology. vol 18. issue 1. 1998-11-05. PMID:9728321. |
octopamine (0.1-1 nmol 1-1) induced a concentration-dependent decrease of [14c]-deoxy-d-glucose uptake into the adipocytes and this inhibition was not influenced by haloperidol at concentrations sufficient to block dopaminergic receptors. |
1998-11-05 |
2023-08-12 |
rat |
| L Björklund, I Strömber. Dopaminergic growth patterns induced by striatal and cortical grafts show differences in sensitivity to increased striatal trophic activity induced by haloperidol. Journal of neuroscience research. vol 53. issue 2. 1998-09-24. PMID:9671973. |
dopaminergic growth patterns induced by striatal and cortical grafts show differences in sensitivity to increased striatal trophic activity induced by haloperidol. |
1998-09-24 |
2023-08-12 |
Not clear |
| L Björklund, I Strömber. Dopaminergic growth patterns induced by striatal and cortical grafts show differences in sensitivity to increased striatal trophic activity induced by haloperidol. Journal of neuroscience research. vol 53. issue 2. 1998-09-24. PMID:9671973. |
chronic treatment with the dopamine antagonist haloperidol increase the neurotrophic activity in striatum, but it is not known how this trophic activity influences different patterns of dopaminergic growth. |
1998-09-24 |
2023-08-12 |
Not clear |
| C V Buhusi, J A Gray, N A Schmaju. Perplexing effects of hippocampal lesions on latent inhibition: a neural network solution. Behavioral neuroscience. vol 112. issue 2. 1998-08-11. PMID:9588481. |
reinstatement of li by haloperidol administration is explained by assuming that dopaminergic antagonists decrease the value of novelty, when novelty increases following hippocampal lesions. |
1998-08-11 |
2023-08-12 |
Not clear |
| Y J Sun, M Suzuki, T Kurachi, M Murata, M Kurach. Expression of Fos protein in the limbic regions of the rat following haloperidol decanoate. Brain research. vol 791. issue 1-2. 1998-08-03. PMID:9593855. |
a single dose of haloperidol to chronic vehicle-treated rats produced significant increases in fos-positive neurons in 18 of 21 brain regions examined including the several cortical areas, caudate-putamen, nucleus accumbens, lateral septum, thalamic nuclei, amygdala, hippocampus ca1, mesencephalic dopaminergic nuclei, and periaqueductal grey. |
1998-08-03 |
2023-08-12 |
rat |
| M F Mazurek, S M Savedia, R S Bobba, S Garside, P I Rosebus. Persistent loss of tyrosine hydroxylase immunoreactivity in the substantia nigra after neuroleptic withdrawal. Journal of neurology, neurosurgery, and psychiatry. vol 64. issue 6. 1998-07-23. PMID:9647315. |
this prompted a study of the effect of an eight week course of haloperidol (hal) followed by two week withdrawal, on dopaminergic neurons of the substantia nigra in rats. |
1998-07-23 |
2023-08-12 |
rat |
| L Ouedraogo, M Magnon, L Sawadogo, R Tricoch. Receptors involved in the positive inotropic action induced by dopamine on the ventricle of a 7-day-old chick embryo heart. Fundamental & clinical pharmacology. vol 12. issue 2. 1998-07-16. PMID:9565766. |
the contribution of dopaminergic receptors in this positive inotropic effect might be of the da-2 receptors since haloperidol used had been reported to be more da-2 than da-1 antagonist. |
1998-07-16 |
2023-08-12 |
chicken |
| F M Gómez, M P Areso, M T Giralt, B Sainz, P García-Vallej. Effects of dopaminergic drugs, occlusal disharmonies, and chronic stress on non-functional masticatory activity in the rat, assessed by incisal attrition. Journal of dental research. vol 77. issue 6. 1998-07-01. PMID:9649174. |
however, neither chronic blockade of dopaminergic receptors with haloperidol, nor its withdrawal, modified attrition. |
1998-07-01 |
2023-08-12 |
rat |
| J J Clifford, J L Waddingto. Heterogeneity of behavioural profile between three new putative selective D3 dopamine receptor antagonists using an ethologically based approach. Psychopharmacology. vol 136. issue 3. 1998-06-16. PMID:9566814. |
this topography of responsivity to u99194a overlapped somewhat with the profiles of both d2-like and d1-like agonists, and its sensitivity to antagonism by haloperidol also indicated a dopaminergic basis thereto. |
1998-06-16 |
2023-08-12 |
Not clear |
| M J Gallagher, H Huang, D R Lync. Modulation of the N-methyl-D-aspartate receptor by haloperidol: NR2B-specific interactions. Journal of neurochemistry. vol 70. issue 5. 1998-05-18. PMID:9572299. |
the dopaminergic antagonist haloperidol has an eight- to 10-fold higher affinity for nmda receptors containing the nr2b (epsilon2) subunit, showing the same subunit specificity as ifenprodil, polyamines, and magnesium. |
1998-05-18 |
2023-08-12 |
Not clear |
| A J Levinson, S Garside, P I Rosebush, M F Mazure. Haloperidol induces persistent down-regulation of tyrosine hydroxylase immunoreactivity in substantia nigra but not ventral tegmental area in the rat. Neuroscience. vol 84. issue 1. 1998-05-08. PMID:9522374. |
we studied the time course of changes in dopaminergic neurons of the substantia nigra and ventral tegmental area following withdrawal of haloperidol. |
1998-05-08 |
2023-08-12 |
rat |
| M A Vital, J C Flório, R Frussa-Filho, R De Lucia, S Tufik, J Palermo-Net. Effects of haloperidol and GM1 ganglioside treatment on striatal D2 receptor binding and dopamine turnover. Life sciences. vol 62. issue 13. 1998-04-06. PMID:9519797. |
previous studies have shown that whereas exogenous gm1 ganglioside co-administration leads to an increase of haloperidol-induced behavioral supersensitivity, gm1 significantly attenuates the behavioral parameters of dopaminergic supersensitivity when administered after abrupt haloperidol withdrawal. |
1998-04-06 |
2023-08-12 |
rat |
| A Zalewska, K Wiśniewsk. Behavioral activity of 1S,3R-ACPD, an agonist of metabotropic glutamate receptors. Polish journal of pharmacology. vol 49. issue 4. 1998-03-02. PMID:9437767. |
doses of 100 and 200 nmole significantly decreased apomorphine-induced stereotypy, and at a dose 200 nmole significantly diminished catalepsy caused by haloperidol, two behavioral symptoms controlled mainly by central dopaminergic system. |
1998-03-02 |
2023-08-12 |
rat |
| U Ziemann, F Tergau, D Bruns, J Baudewig, W Paulu. Changes in human motor cortex excitability induced by dopaminergic and anti-dopaminergic drugs. Electroencephalography and clinical neurophysiology. vol 105. issue 6. 1998-02-05. PMID:9448644. |
transcranial magnetic stimulation was used to probe the acute effect of a single oral dose of various dopaminergic (levodopa, selegiline, bromocriptine) and antidopaminergic drugs (sulpiride, haloperidol) on motor cortex excitability in healthy volunteers. |
1998-02-05 |
2023-08-12 |
human |
| J A Gray, P M Moran, G Grigoryan, S L Peters, A M Young, M H Josep. Latent inhibition: the nucleus accumbens connection revisited. Behavioural brain research. vol 88. issue 1. 1998-02-04. PMID:9401705. |
new evidence in support of this hypothesis is presented or reviewed here, showing that: (1) intra-accumbens injection of haloperidol at the time of conditioning potentiates li; (2) destruction of dopaminergic terminals in the nucleus accumbens potentiates li; (3) intra-accumbens haloperidol reverses the blockade of li caused by systemic nicotine; (4) intra-accumbens haloperidol reverses the blockade of li caused by systemic amphetamine; (5) after a single systemic injection of amphetamine (insufficient on its own to block li), a subsequent intra-accumbens injection of amphetamine at the time of conditioning blocks li; and (6) intra-accumbens (like systemic) amphetamine administered 15 min before conditioning, without prior systemic amphetamine, failed to block li. |
1998-02-04 |
2023-08-12 |
human |