| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J M Wilson, S J Kis. The vesicular monoamine transporter, in contrast to the dopamine transporter, is not altered by chronic cocaine self-administration in the rat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 10. 1996-06-21. PMID:8627383. |
the vesicular monoamine transporter, in contrast to the dopamine transporter, is not altered by chronic cocaine self-administration in the rat. |
1996-06-21 |
2023-08-12 |
rat |
| J M Wilson, S J Kis. The vesicular monoamine transporter, in contrast to the dopamine transporter, is not altered by chronic cocaine self-administration in the rat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 10. 1996-06-21. PMID:8627383. |
in the present investigation, we used a chronic, unlimited-access, cocaine self-administration paradigm to determine whether brain levels of vmat2, as estimated using [3h]dihydrotetrabenazine (dtbz) binding, are altered by chronic exposure to a dopamine uptake blocker. |
1996-06-21 |
2023-08-12 |
rat |
| N H Chen, C Xu, L L Coffey, M E Reit. [3H]WIN 35,428 [2 beta-carbomethoxy-3 beta-(4-fluorophenyl)tropane] binding to rat brain membranes. Comparing dopamine cell body areas with nerve terminal regions. Biochemical pharmacology. vol 51. issue 4. 1996-06-13. PMID:8619903. |
the results suggest that somatodendritic and axonal dopamine transporters in the ventral mesencephalon and nucleus accumbens are not very different as far as their binding domains for uptake blockers such as cocaine and gbr 12909 are concerned. |
1996-06-13 |
2023-08-12 |
rat |
| W Wieczorek, Z L Kru. Influences of neuronal uptake and D2 autoreceptors on regulation of extracellular dopamine in the core, shell and rostral pole of the rat nucleus accumbens. Brain research. vol 699. issue 2. 1996-06-12. PMID:8616619. |
one microm (-)-sulpiride, significantly increased dopamine overflow in all 3 regions but only when the duration of stimulation was greater than 500 ms. one microm cocaine, significantly potentiated dopamine overflow in all 3 regions following all patterns of stimulation. |
1996-06-12 |
2023-08-12 |
rat |
| W Wieczorek, Z L Kru. Influences of neuronal uptake and D2 autoreceptors on regulation of extracellular dopamine in the core, shell and rostral pole of the rat nucleus accumbens. Brain research. vol 699. issue 2. 1996-06-12. PMID:8616619. |
in the presence of 1 microm cocaine, superfusion with 1 microm (-)-sulpiride did not result in a further increase in dopamine overflow at any frequency of stimulation in the rostral pole, but significant increases in dopamine overflow were observed after stimulation with 20 pulses at 10 or 20 hz in the core or shell; the degree of potentiation was greater in the shell than core. |
1996-06-12 |
2023-08-12 |
rat |
| F E Pontieri, G Tanda, G Di Chiar. Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 92. issue 26. 1996-06-07. PMID:8618890. |
intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens. |
1996-06-07 |
2023-08-12 |
rat |
| F E Pontieri, G Tanda, G Di Chiar. Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 92. issue 26. 1996-06-07. PMID:8618890. |
the present study investigated the effect in freely moving rats of intravenous cocaine, amphetamine, and morphine on extracellular dopamine concentrations in the nucleus accumbens shell and core by means of microdialysis with vertically implanted concentric probes. |
1996-06-07 |
2023-08-12 |
rat |
| F E Pontieri, G Tanda, G Di Chiar. Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 92. issue 26. 1996-06-07. PMID:8618890. |
morphine, at 0.2 and 0.4 mg/kg, and cocaine, at 0.5 mg/kg, increased extracellular dopamine selectivity in the shell. |
1996-06-07 |
2023-08-12 |
rat |
| F E Pontieri, G Tanda, G Di Chiar. Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 92. issue 26. 1996-06-07. PMID:8618890. |
higher doses of cocaine (1.0 mg/kg) and the lowest dose of amphetamine tested (0.125 mg/kg) increased extracellular dopamine both in the shell and in the core, but the effect was significantly more pronounced in the shell compared with the core. |
1996-06-07 |
2023-08-12 |
rat |
| J B Acri, B K Siedleck, J M Witki. Effects of benztropine on behavioral and toxic effects of cocaine: comparison with atropine and the selective dopamine uptake inhibitor 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl-propyl)-piperazine. The Journal of pharmacology and experimental therapeutics. vol 277. issue 1. 1996-06-06. PMID:8613919. |
effects of benztropine on behavioral and toxic effects of cocaine: comparison with atropine and the selective dopamine uptake inhibitor 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl-propyl)-piperazine. |
1996-06-06 |
2023-08-12 |
mouse |
| J B Acri, B K Siedleck, J M Witki. Effects of benztropine on behavioral and toxic effects of cocaine: comparison with atropine and the selective dopamine uptake inhibitor 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl-propyl)-piperazine. The Journal of pharmacology and experimental therapeutics. vol 277. issue 1. 1996-06-06. PMID:8613919. |
behavioral effects of cocaine that are relevant to its abuse have been associated with pharmacological actions at the dopamine uptake carrier. |
1996-06-06 |
2023-08-12 |
mouse |
| J B Acri, B K Siedleck, J M Witki. Effects of benztropine on behavioral and toxic effects of cocaine: comparison with atropine and the selective dopamine uptake inhibitor 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl-propyl)-piperazine. The Journal of pharmacology and experimental therapeutics. vol 277. issue 1. 1996-06-06. PMID:8613919. |
benztropine (cogentin) is an antiparkinson agent that has limited abuse despite its ability to block dopamine uptake, and has been suggested as a candidate for the treatment of cocaine dependence. |
1996-06-06 |
2023-08-12 |
mouse |
| R M Carelli, S A Deadwyle. Dose-dependent transitions in nucleus accumbens cell firing and behavioral responding during cocaine self-administration sessions in rats. The Journal of pharmacology and experimental therapeutics. vol 277. issue 1. 1996-06-06. PMID:8613945. |
pretreatment with the dopamine d1 receptor antagonist sch23390 (5 or 10 microgram/kg) prolonged the onset of na patterned discharges, similar to responding for low doses of cocaine (0.08 and 0.16 mg/inf. |
1996-06-06 |
2023-08-12 |
rat |
| L W Fitzgerald, J Ortiz, A G Hamedani, E J Nestle. Drugs of abuse and stress increase the expression of GluR1 and NMDAR1 glutamate receptor subunits in the rat ventral tegmental area: common adaptations among cross-sensitizing agents. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 1. 1996-06-03. PMID:8613793. |
we therefore examined the effect of repeated cocaine treatment on glutamate receptor subunit expression in central dopamine (da) pathways implicated in many of cocaine's behavioral actions. |
1996-06-03 |
2023-08-12 |
rat |
| Z de Saint Hilaire, A Python, G Blanc, Y Charnay, J M Gaillar. Effects of WIN 35,428 a potent antagonist of dopamine transporter on sleep and locomotor activity in rats. Neuroreport. vol 6. issue 16. 1996-04-18. PMID:8595198. |
the new cocaine derivative cft naphthalene sulphonate (win 35,428), has been shown to have a considerably longer duration of action and greater potency than cocaine as a central stimulant and it appears to have a similar mode of action on dopamine (da) systems. |
1996-04-18 |
2023-08-12 |
rat |
| T Kano, Y Suzuki, M Shibuya, K Kiuchi, M Hagiwar. Cocaine-induced CREB phosphorylation and c-Fos expression are suppressed in Parkinsonism model mice. Neuroreport. vol 6. issue 16. 1996-04-18. PMID:8595201. |
cocaine exerts multiple neurochemical effects in the central nervous system through inhibition of the dopamine transporter at the synapse. |
1996-04-18 |
2023-08-12 |
mouse |
| B S Kolachana, R C Saunders, D R Weinberge. Augmentation of prefrontal cortical monoaminergic activity inhibits dopamine release in the caudate nucleus: an in vivo neurochemical assessment in the rhesus monkey. Neuroscience. vol 69. issue 3. 1996-04-18. PMID:8596654. |
increase of monoaminergic activity by infusion of either d-amphetamine (100 microm) or cocaine hydrochloride (100 microm) resulted in a gradual and prolonged decrease in caudate nucleus dopamine levels. |
1996-04-18 |
2023-08-12 |
monkey |
| B M Prasad, B A Sorg, C Ulibarri, P W Kaliva. Sensitization to stress and psychostimulants. Involvement of dopamine transmission versus the HPA axis. Annals of the New York Academy of Sciences. vol 771. 1996-04-17. PMID:8597435. |
this behavioral cross-sensitization between stress (repeated mild footshock) and cocaine (15 mg/kg, ip) is associated with an increase in extracellular dopamine in the nucleus accumbens, but a decrease in the prefrontal cortex. |
1996-04-17 |
2023-08-12 |
rat |
| J Chen, R Marmur, W Paredes, A Pulles, E L Gardne. Systemic cocaine challenge after chronic cocaine treatment reveals sensitization of extracellular dopamine levels in nucleus accumbens but direct cocaine perfusion into nucleus accumbens does not: implications for the neural locus of cocaine sensitization. Life sciences. vol 58. issue 8. 1996-04-10. PMID:8594313. |
systemic cocaine challenge after chronic cocaine treatment reveals sensitization of extracellular dopamine levels in nucleus accumbens but direct cocaine perfusion into nucleus accumbens does not: implications for the neural locus of cocaine sensitization. |
1996-04-10 |
2023-08-12 |
rat |
| J Chen, R Marmur, W Paredes, A Pulles, E L Gardne. Systemic cocaine challenge after chronic cocaine treatment reveals sensitization of extracellular dopamine levels in nucleus accumbens but direct cocaine perfusion into nucleus accumbens does not: implications for the neural locus of cocaine sensitization. Life sciences. vol 58. issue 8. 1996-04-10. PMID:8594313. |
on the next day, rats were challenged with an acute dose of cocaine administered by one of two routes (systemic or intracranial), and extra-cellular dopamine (da) in the nucleus accumbens (acb) was measured by in vivo microdialysis. |
1996-04-10 |
2023-08-12 |
rat |