| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K J Buck, S G Amar. Structural domains of catecholamine transporter chimeras involved in selective inhibition by antidepressants and psychomotor stimulants. Molecular pharmacology. vol 48. issue 6. 1996-10-22. PMID:8848002. |
in contrast, all chimeras containing dopamine transporter sequences from this region resemble the dopamine transporter, which demonstrates higher affinity for psychomotor stimulants compared with antidepressants (e.g., ki = 391 +/- 39 nm cocaine compared with 9365 +/- 1260 nm desipramine). |
1996-10-22 |
2023-08-12 |
Not clear |
| E D French, K Dillon, S F Al. Effects of ibogaine, and cocaine and morphine after ibogaine, on ventral tegmental dopamine neurons. Life sciences. vol 59. issue 12. 1996-10-21. PMID:8809219. |
effects of ibogaine, and cocaine and morphine after ibogaine, on ventral tegmental dopamine neurons. |
1996-10-21 |
2023-08-12 |
Not clear |
| E D French, K Dillon, S F Al. Effects of ibogaine, and cocaine and morphine after ibogaine, on ventral tegmental dopamine neurons. Life sciences. vol 59. issue 12. 1996-10-21. PMID:8809219. |
therefore, the present study was designed to determine: (1) the acute effects of ibogaine on the activity of vta dopamine neurons, and (2) whether ibogaine pretreatment causes a persistent modification of the dopamine neuronal response to morphine and cocaine. |
1996-10-21 |
2023-08-12 |
Not clear |
| E D French, K Dillon, S F Al. Effects of ibogaine, and cocaine and morphine after ibogaine, on ventral tegmental dopamine neurons. Life sciences. vol 59. issue 12. 1996-10-21. PMID:8809219. |
however, ibogaine pretreatment (6-8 hr and 19 hr before) failed to alter either the spontaneous activity of vta neurons, or the response of these dopamine neurons to morphine or cocaine. |
1996-10-21 |
2023-08-12 |
Not clear |
| I Ushijima, Y Mizuki, M Yamad. Alteration of cataleptic responses induced by dopamine receptor antagonists after chronic cocaine administration in mice. European journal of pharmacology. vol 285. issue 1. 1996-10-21. PMID:8846811. |
the influence of chronic treatment of mice with cocaine, an indirect dopamine receptor agonist, on the cataleptic effects of r-(+)-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1h-3-benzazepin- 7ol hydrochloride (sch23390), a dopamine d1 receptor antagonist, or haloperidol, mainly a dopamine d2 receptor antagonist, was investigated. |
1996-10-21 |
2023-08-12 |
mouse |
| I Ushijima, Y Mizuki, M Yamad. Alteration of cataleptic responses induced by dopamine receptor antagonists after chronic cocaine administration in mice. European journal of pharmacology. vol 285. issue 1. 1996-10-21. PMID:8846811. |
these results suggest that chronic treatment with the indirect dopamine receptor agonist, cocaine, caused supersensitivity of dopamine d1 receptors (a decrease in sch23390 catalepsy) during the early withdrawal period and subsensitivity (an increase in sch23390 catalepsy) after a longer period of withdrawal. |
1996-10-21 |
2023-08-12 |
mouse |
| I Ushijima, Y Mizuki, M Yamad. Alteration of cataleptic responses induced by dopamine receptor antagonists after chronic cocaine administration in mice. European journal of pharmacology. vol 285. issue 1. 1996-10-21. PMID:8846811. |
it was apparent that the longer the period and the higher the dose of pretreatment with cocaine, the less were the alterations in initial responses and the greater were the alterations in subsequent responses to the dopamine d1 receptor antagonists. |
1996-10-21 |
2023-08-12 |
mouse |
| T Suzuki, Y Sugano, M Funada, M Misaw. Adrenalectomy potentiates the morphine--but not cocaine-induced place preference in rats. Life sciences. vol 56. issue 17. 1996-10-21. PMID:8847945. |
in the present study, we found that adx potentiates the reinforcing effect induced by morphine, but not that induced by cocaine, which suggests that the enhancement by adx may be due to a change in opioid receptors, morphine metabolism and/or some other cause, but not a change in dopamine receptors. |
1996-10-21 |
2023-08-12 |
rat |
| J Y Chan, C L Huang, S H Cha. Nitric oxide as a mediator of cocaine-induced penile erection in the rat. British journal of pharmacology. vol 118. issue 1. 1996-10-10. PMID:8733589. |
the potential involvement of dopamine, noradrenaline or nitric oxide as the chemical mediator in this process, and the pharmacological action of cocaine as a local anaesthetic in the induced increase in icp, were also investigated. |
1996-10-10 |
2023-08-12 |
rat |
| J Y Chan, C L Huang, S H Cha. Nitric oxide as a mediator of cocaine-induced penile erection in the rat. British journal of pharmacology. vol 118. issue 1. 1996-10-10. PMID:8733589. |
this process did not appear to involve either dopamine or noradrenaline as the chemical mediator, nor the pharmacological action of cocaine as a local anaesthetic. |
1996-10-10 |
2023-08-12 |
rat |
| B Ferger, D Stahl, K Kuschinsk. Effects of cocaine on the EEG power spectrum of rats are significantly altered after its repeated administration: do they reflect sensitization phenomena? Naunyn-Schmiedeberg's archives of pharmacology. vol 353. issue 5. 1996-10-08. PMID:8740148. |
this observation demonstrates that sensitization to cocaine can be manifest in the eeg and that after a certain dosage, a shift from an activation of d1-like dopamine receptors to an additional activation of d2-like receptors becomes obvious. |
1996-10-08 |
2023-08-12 |
rat |
| L H Parsons, S B Caine, P Sokoloff, J C Schwartz, G F Koob, F Weis. Neurochemical evidence that postsynaptic nucleus accumbens D3 receptor stimulation enhances cocaine reinforcement. Journal of neurochemistry. vol 67. issue 3. 1996-10-02. PMID:8752115. |
the mechanism by which two d3 receptor-preferring agonists, 7-hydroxydipropylaminotetralin (7-oh-dpat) and quinelorane, modulate cocaine reinforcement was examined by monitoring nucleus accumbens dopamine levels with in vivo microdialysis while rats intravenously self-administered the following four different drug solutions consecutively: (1) cocaine; (2) a combination of cocaine plus a low dose of either agonist; (3) either agonist alone; and finally, (4) a physiological saline solution. |
1996-10-02 |
2023-08-12 |
rat |
| L H Parsons, S B Caine, P Sokoloff, J C Schwartz, G F Koob, F Weis. Neurochemical evidence that postsynaptic nucleus accumbens D3 receptor stimulation enhances cocaine reinforcement. Journal of neurochemistry. vol 67. issue 3. 1996-10-02. PMID:8752115. |
both 7-oh-dpat (4 micrograms/infusion) and quinelorane (0.25 microgram/infusion) decreased cocaine (0.25 mg/infusion) intake in a manner indicating an enhancement of cocaine reinforcement and simultaneously decreased the cocaine-induced elevations in nucleus accumbens dopamine levels by > 50%. |
1996-10-02 |
2023-08-12 |
rat |
| K Y Little, U N Patel, T B Clark, J D Butt. Alteration of brain dopamine and serotonin levels in cocaine users: a preliminary report. The American journal of psychiatry. vol 153. issue 9. 1996-10-02. PMID:8780430. |
alteration of brain dopamine and serotonin levels in cocaine users: a preliminary report. |
1996-10-02 |
2023-08-12 |
Not clear |
| K Y Little, U N Patel, T B Clark, J D Butt. Alteration of brain dopamine and serotonin levels in cocaine users: a preliminary report. The American journal of psychiatry. vol 153. issue 9. 1996-10-02. PMID:8780430. |
this study tested the hypothesis that cocaine depletes dopamine levels in the brain. |
1996-10-02 |
2023-08-12 |
Not clear |
| H Sershen, A Hashim, A Lajth. Effect of ibogaine on cocaine-induced efflux of [3H] dopamine and [3H] serotonin from mouse striatum. Pharmacology, biochemistry, and behavior. vol 53. issue 4. 1996-09-30. PMID:8801590. |
cocaine (10(-6) m) added in vitro increased tthe fractional efflux of both [3h]dopamine (frs2/frs1 = 2.42 +/- 0.36) and [3h]serotonin (frs2/frs1 = 1.31 +/- 0.06). |
1996-09-30 |
2023-08-12 |
mouse |
| G I Elmer, A Brockington, D A Gorelick, F I Carrol, K C Rice, D Matecka, S R Goldberg, R B Rothma. Cocaine cross-sensitization to dopamine uptake inhibitors: unique effects of GBR12909. Pharmacology, biochemistry, and behavior. vol 53. issue 4. 1996-09-30. PMID:8801597. |
cocaine cross-sensitization to dopamine uptake inhibitors: unique effects of gbr12909. |
1996-09-30 |
2023-08-12 |
Not clear |
| G I Elmer, A Brockington, D A Gorelick, F I Carrol, K C Rice, D Matecka, S R Goldberg, R B Rothma. Cocaine cross-sensitization to dopamine uptake inhibitors: unique effects of GBR12909. Pharmacology, biochemistry, and behavior. vol 53. issue 4. 1996-09-30. PMID:8801597. |
the purpose of the current experiment was to investigate the ability of cocaine to cross-sensitize the locomotor effects of several dopamine uptake blockers with unique pharmacological profiles. |
1996-09-30 |
2023-08-12 |
Not clear |
| D Boulay, D Duterte-Boucher, I Leroux-Nicollet, L Naudon, J Costenti. Locomotor sensitization and decrease in [3H]mazindol binding to the dopamine transporter in the nucleus accumbens are delayed after chronic treatments by GBR12783 or cocaine. The Journal of pharmacology and experimental therapeutics. vol 278. issue 1. 1996-09-23. PMID:8764367. |
locomotor sensitization and decrease in [3h]mazindol binding to the dopamine transporter in the nucleus accumbens are delayed after chronic treatments by gbr12783 or cocaine. |
1996-09-23 |
2023-08-12 |
rat |
| D Boulay, D Duterte-Boucher, I Leroux-Nicollet, L Naudon, J Costenti. Locomotor sensitization and decrease in [3H]mazindol binding to the dopamine transporter in the nucleus accumbens are delayed after chronic treatments by GBR12783 or cocaine. The Journal of pharmacology and experimental therapeutics. vol 278. issue 1. 1996-09-23. PMID:8764367. |
rats were treated once daily for 15 consecutive days with either cocaine or the specific dopamine uptake inhibitor 1-[2- (diphenylmethoxy)ethyl]-4-(3-phenyl-2-(propenyl)-piperazine (gbr12783) at a dose (10 mg/kg) that given acutely increases locomotor activity. |
1996-09-23 |
2023-08-12 |
rat |