| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| X Lamas, S S Negus, M A Nader, N K Mell. Effects of the putative dopamine D3 receptor agonist 7-OH-DPAT in rhesus monkeys trained to discriminate cocaine from saline. Psychopharmacology. vol 124. issue 4. 1996-11-25. PMID:8739545. |
effects of the putative dopamine d3 receptor agonist 7-oh-dpat in rhesus monkeys trained to discriminate cocaine from saline. |
1996-11-25 |
2023-08-12 |
monkey |
| X Lamas, S S Negus, M A Nader, N K Mell. Effects of the putative dopamine D3 receptor agonist 7-OH-DPAT in rhesus monkeys trained to discriminate cocaine from saline. Psychopharmacology. vol 124. issue 4. 1996-11-25. PMID:8739545. |
these studies were designed to evaluate the effects of the putative dopamine d3 receptor agonist 7-hydroxy-n,n-di-n-propyl-2-aminotetraline (7-oh-dpat), alone and in combination with cocaine, in four rhesus monkeys trained to discriminate cocaine (0.4 mg/kg, im) from saline under a fixed-ratio 30 schedule of food presentation. |
1996-11-25 |
2023-08-12 |
monkey |
| X Lamas, S S Negus, M A Nader, N K Mell. Effects of the putative dopamine D3 receptor agonist 7-OH-DPAT in rhesus monkeys trained to discriminate cocaine from saline. Psychopharmacology. vol 124. issue 4. 1996-11-25. PMID:8739545. |
finally, the d3/d2 dopamine agonist quinpirole completely generalized to cocaine in three monkeys, and partially in the fourth monkey. |
1996-11-25 |
2023-08-12 |
monkey |
| C Ollo, T N Alim, R B Rosse, T Lindquist, T Green, T Gillis, J Ricci, M Khan, S I Deutsc. Lack of neurotoxic effect of diethylpropion in crack-cocaine abusers. Clinical neuropharmacology. vol 19. issue 1. 1996-11-15. PMID:8867517. |
dopamine agonists have been used with some success in treating cocaine addiction. |
1996-11-15 |
2023-08-12 |
Not clear |
| N D Volkow, G J Wang, J S Fowler, S J Gatley, Y S Ding, J Logan, S L Dewey, R Hitzemann, J Lieberma. Relationship between psychostimulant-induced "high" and dopamine transporter occupancy. Proceedings of the National Academy of Sciences of the United States of America. vol 93. issue 19. 1996-11-13. PMID:8816810. |
the ability of cocaine to inhibit the dopamine transporter (dat) appears to be crucial for its reinforcing properties. |
1996-11-13 |
2023-08-12 |
human |
| J M Wilson, A I Levey, C Bergeron, K Kalasinsky, L Ang, F Peretti, V I Adams, J Smialek, W R Anderson, K Shannak, J Deck, H B Niznik, S J Kis. Striatal dopamine, dopamine transporter, and vesicular monoamine transporter in chronic cocaine users. Annals of neurology. vol 40. issue 3. 1996-11-12. PMID:8797532. |
striatal dopamine, dopamine transporter, and vesicular monoamine transporter in chronic cocaine users. |
1996-11-12 |
2023-08-12 |
human |
| J M Wilson, A I Levey, C Bergeron, K Kalasinsky, L Ang, F Peretti, V I Adams, J Smialek, W R Anderson, K Shannak, J Deck, H B Niznik, S J Kis. Striatal dopamine, dopamine transporter, and vesicular monoamine transporter in chronic cocaine users. Annals of neurology. vol 40. issue 3. 1996-11-12. PMID:8797532. |
depletion of striatal dopamine (da) has been hypothesized to explain some of the neurological and psychiatric complications of chronic use of cocaine, including increased risk for neuroleptic-precipitated movement disorders. |
1996-11-12 |
2023-08-12 |
human |
| K Matthews, B A Baldo, A Markou, O Lown, D H Overstreet, G F Koo. Rewarding electrical brain stimulation: similar thresholds for Flinders Sensitive Line Hypercholinergic and Flinders Resistant Line Hypocholinergic rats. Physiology & behavior. vol 59. issue 6. 1996-11-08. PMID:8737906. |
all animals were tested in a rate-free, current-threshold brain stimulation-reward paradigm, following acute challenges with the monoamine reuptake inhibitor cocaine, the dopamine d1 receptor antagonist sch-23390, the cholinergic muscarinic antagonist scopolamine, and the serotonin reuptake inhibitor fluoxetine. |
1996-11-08 |
2023-08-12 |
human |
| C L Coulter, H K Happe, L C Murri. Postnatal development of the dopamine transporter: a quantitative autoradiographic study. Brain research. Developmental brain research. vol 92. issue 2. 1996-11-08. PMID:8738124. |
knowledge of the differential developmental patterns of the dopamine transporter in different brain regions may have implications for understanding the neurodevelopmental effects of prenatal cocaine exposure. |
1996-11-08 |
2023-08-12 |
rat |
| N S Pilotte, L G Sharpe, S D Rountree, M J Kuha. Cocaine withdrawal reduces dopamine transporter binding in the shell of the nucleus accumbens. Synapse (New York, N.Y.). vol 22. issue 1. 1996-11-08. PMID:8822482. |
cocaine withdrawal reduces dopamine transporter binding in the shell of the nucleus accumbens. |
1996-11-08 |
2023-08-12 |
rat |
| N S Pilotte, L G Sharpe, S D Rountree, M J Kuha. Cocaine withdrawal reduces dopamine transporter binding in the shell of the nucleus accumbens. Synapse (New York, N.Y.). vol 22. issue 1. 1996-11-08. PMID:8822482. |
we have previously shown that withdrawal from repeated, intermittent infusions of cocaine in lewis rats results in a long-lasting reduction in dopamine transporter levels in the nucleus accumbens. |
1996-11-08 |
2023-08-12 |
rat |
| G R Uhl, D J Vandenbergh, L L Mine. Knockout mice and dirty drugs. Drug addiction. Current biology : CB. vol 6. issue 8. 1996-11-07. PMID:8805320. |
recent studies with knockout mice implicate the dopamine transporter as the target of the locomotor effects of the addictive psychomotor drugs cocaine and amphetamine; studies of reward in these animals are eagerly awaited. |
1996-11-07 |
2023-08-12 |
mouse |
| R D Spealma. Dopamine D3 receptor agonists partially reproduce the discriminative stimulus effects of cocaine in squirrel monkeys. The Journal of pharmacology and experimental therapeutics. vol 278. issue 3. 1996-11-05. PMID:8819495. |
dopamine d3 receptor agonists partially reproduce the discriminative stimulus effects of cocaine in squirrel monkeys. |
1996-11-05 |
2023-08-12 |
human |
| R D Spealma. Dopamine D3 receptor agonists partially reproduce the discriminative stimulus effects of cocaine in squirrel monkeys. The Journal of pharmacology and experimental therapeutics. vol 278. issue 3. 1996-11-05. PMID:8819495. |
dopamine agonists and antagonists varying in affinity and selectivity at the d3 subtype of d2-like receptors were studied in squirrel monkeys trained to discriminate cocaine from vehicle in a two-lever choice procedure. |
1996-11-05 |
2023-08-12 |
human |
| N A Darman. Differential potentiation of L-tryptophan-induced head-twitch response in mice by cocaine and sertraline. Life sciences. vol 59. issue 14. 1996-10-31. PMID:8831798. |
in the present study, we have investigated the effects of cocaine and the selective 5-ht (sertraline), norepinephrine (nisoxetine) and dopamine (gbr 12935) uptake inhibitors on the l-tryptophan-induced htr in the presence of a nonselective monoamine oxidase inhibitor, tranylcypromine. |
1996-10-31 |
2023-08-12 |
mouse |
| M J Kuhar, N S Pilott. Neurochemical changes in cocaine withdrawal. Trends in pharmacological sciences. vol 17. issue 7. 1996-10-28. PMID:8756185. |
cocaine withdrawal in animals causes a transient increase followed by a long-lasting decrease in mesolimbic dopamine transporters, dopamine efflux and the number of dopamine cells firing spontaneously. |
1996-10-28 |
2023-08-12 |
Not clear |
| Y Egilmez, M E Jung, J D Lane, M W Emmett-Oglesb. Dopamine release during cocaine self-administration in rats: effect of SCH23390. Brain research. vol 701. issue 1-2. 1996-10-25. PMID:8925277. |
dopamine release during cocaine self-administration in rats: effect of sch23390. |
1996-10-25 |
2023-08-12 |
rat |
| Y Egilmez, M E Jung, J D Lane, M W Emmett-Oglesb. Dopamine release during cocaine self-administration in rats: effect of SCH23390. Brain research. vol 701. issue 1-2. 1996-10-25. PMID:8925277. |
this experiment tested the hypotheses that: (1) self-administration of cocaine would produce an increase in dopamine (da) oxidation current in the nucleus accumbens (n. |
1996-10-25 |
2023-08-12 |
rat |
| L Jones, I Fischer, P Levit. Nonuniform alteration of dendritic development in the cerebral cortex following prenatal cocaine exposure. Cerebral cortex (New York, N.Y. : 1991). vol 6. issue 3. 1996-10-24. PMID:8670669. |
analysis of brain development focused on two areas of the cerebral cortex, anterior cingulate and primary visual, in which dopamine afferents, a target of cocaine, are differentially distributed. |
1996-10-24 |
2023-08-12 |
Not clear |
| R De La Garza, P M Callahan, K A Cunningha. Detailed investigations of 5-HT3 compounds in a drug discrimination model. Pharmacology, biochemistry, and behavior. vol 54. issue 3. 1996-10-24. PMID:8743626. |
serotonin type-3 (5-ht3) receptors modulate both dopamine (da) release and locomotor stimulation induced by cocaine, yet appear to be ineffective at blocking its stimulus and reinforcing effects. |
1996-10-24 |
2023-08-12 |
rat |