| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Friedman, E Yadin, H Y Wan. Effect of prenatal cocaine on dopamine receptor-G protein coupling in mesocortical regions of the rabbit brain. Neuroscience. vol 70. issue 3. 1997-03-06. PMID:9045085. |
furthermore, prenatal cocaine did not affect [3h]8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1h-3-benzazepin-7- olhemimaleate binding to cortical d1 dopamine receptors. |
1997-03-06 |
2023-08-12 |
rabbit |
| J Z Little, T J Teyle. In utero cocaine exposure decreases dopamine D1 receptor modulation of hippocampal long-term potentiation in the rabbit. Neuroscience letters. vol 215. issue 3. 1997-02-28. PMID:8899737. |
in utero cocaine exposure decreases dopamine d1 receptor modulation of hippocampal long-term potentiation in the rabbit. |
1997-02-28 |
2023-08-12 |
rabbit |
| J Z Little, T J Teyle. In utero cocaine exposure decreases dopamine D1 receptor modulation of hippocampal long-term potentiation in the rabbit. Neuroscience letters. vol 215. issue 3. 1997-02-28. PMID:8899737. |
disturbances of behavior and cellular physiology have been associated with prenatal cocaine exposure and are related to changes in dopamine transmission. |
1997-02-28 |
2023-08-12 |
rabbit |
| T Belej, D Manji, S Sioutis, H M Barros, J N Nobreg. Changes in serotonin and norepinephrine uptake sites after chronic cocaine: pre- vs. post-withdrawal effects. Brain research. vol 736. issue 1-2. 1997-02-26. PMID:8930335. |
although acute cocaine is a strong reuptake inhibitor at dopamine (da), norepinephrine (ne) and serotonin (5-ht) synapses, the effects of chronic cocaine on 5-ht and ne transporters have received less attention than its effects on da transporters. |
1997-02-26 |
2023-08-12 |
rat |
| J Harvey, M G Lace. Endogenous and exogenous dopamine depress EPSCs in rat nucleus accumbens in vitro via D1 receptors activation. The Journal of physiology. vol 492 ( Pt 1). 1997-02-21. PMID:8730590. |
epscs were reversibly depressed by the dopamine mimetic psychostimulants cocaine (1-20 microm) and amphetamine (10-30 microm) by 40 +/- 16 and 62 +/- 9%, respectively, but only in about half of the cells tested (11/23 and 6/13, respectively). |
1997-02-21 |
2023-08-12 |
rat |
| J Harvey, M G Lace. Endogenous and exogenous dopamine depress EPSCs in rat nucleus accumbens in vitro via D1 receptors activation. The Journal of physiology. vol 492 ( Pt 1). 1997-02-21. PMID:8730590. |
no discernable effects of dopamine, skf 81297a, skf 38393, quinpirole, cocaine or amphetamine were observed on membrane conductance or holding current (at holding potentials of -80 to -90 mv), suggesting that the depression of the epsc was solely due to an action on presynaptic d1 receptors. |
1997-02-21 |
2023-08-12 |
rat |
| T A Grady, A Broocks, S K Canter, T A Pigott, B Dubbert, J L Hill, D L Murph. Biological and behavioral responses to D-amphetamine, alone and in combination with the serotonin3 receptor antagonist ondansetron, in healthy volunteers. Psychiatry research. vol 64. issue 1. 1997-02-21. PMID:8888359. |
evidence that serotonin3 (5-hydroxytryptamine3, 5-ht3) antagonists attenuate behavioral responses to d-amphetamine and cocaine suggests that 5-ht3 receptors modulate brain dopamine in animals. |
1997-02-21 |
2023-08-12 |
human |
| R M Craft, J A Stratman. Discriminative stimulus effects of cocaine in female versus male rats. Drug and alcohol dependence. vol 42. issue 1. 1997-02-21. PMID:8889401. |
the dopamine antagonist fluphenazine blocked the discriminative stimulus effects of cocaine to approximately the same extent in both sexes. |
1997-02-21 |
2023-08-12 |
rat |
| B Geter-Douglass, A L Rile. Dopamine D1/D2 antagonist combinations as antagonists of the discriminative stimulus effects of cocaine. Pharmacology, biochemistry, and behavior. vol 54. issue 2. 1997-02-12. PMID:8743607. |
dopamine d1/d2 antagonist combinations as antagonists of the discriminative stimulus effects of cocaine. |
1997-02-12 |
2023-08-12 |
rat |
| B Geter-Douglass, A L Rile. Dopamine D1/D2 antagonist combinations as antagonists of the discriminative stimulus effects of cocaine. Pharmacology, biochemistry, and behavior. vol 54. issue 2. 1997-02-12. PMID:8743607. |
although data suggest that the dopaminergic system mediates the discriminative stimulus effects of cocaine, neither selective d1 or d2 dopamine agonists nor selective d1 or d2 antagonists substitute reliably for or consistently block these effects. |
1997-02-12 |
2023-08-12 |
rat |
| L Koetzner, A L Riley, J R Glow. Discriminative stimulus effects of dopaminergic agents in rhesus monkeys. Pharmacology, biochemistry, and behavior. vol 54. issue 2. 1997-02-12. PMID:8743617. |
recent reports have shown that treatment with dopamine reuptake inhibitors can selectively decrease responding maintained by low doses of cocaine in rhesus monkeys. |
1997-02-12 |
2023-08-12 |
monkey |
| L Koetzner, A L Riley, J R Glow. Discriminative stimulus effects of dopaminergic agents in rhesus monkeys. Pharmacology, biochemistry, and behavior. vol 54. issue 2. 1997-02-12. PMID:8743617. |
one behavioral effect that dopamine reuptake inhibitors and cocaine share is their ability to serve as a discriminative stimulus. |
1997-02-12 |
2023-08-12 |
monkey |
| A E Fleckenstein, T A Kopajtic, J W Boja, F I Carroll, M J Kuha. Highly potent cocaine analogs cause long-lasting increases in locomotor activity. European journal of pharmacology. vol 311. issue 2-3. 1997-02-12. PMID:8891589. |
three cocaine analogs were compared with cocaine for the capacity to affect: (1) dopamine transporter binding and function; and (2) locomotor activity. |
1997-02-12 |
2023-08-12 |
mouse |
| A E Fleckenstein, T A Kopajtic, J W Boja, F I Carroll, M J Kuha. Highly potent cocaine analogs cause long-lasting increases in locomotor activity. European journal of pharmacology. vol 311. issue 2-3. 1997-02-12. PMID:8891589. |
these analogs inhibited [3h]dopamine transport into rat striatal synaptosomes, with ic50 values again less (at least 100-fold) than that for cocaine. |
1997-02-12 |
2023-08-12 |
mouse |
| S Y Chen, R I Burger, M E Reit. Extracellular dopamine in the rat ventral tegmental area and nucleus accumbens following ventral tegmental infusion of cocaine. Brain research. vol 729. issue 2. 1997-02-07. PMID:8877004. |
extracellular dopamine in the rat ventral tegmental area and nucleus accumbens following ventral tegmental infusion of cocaine. |
1997-02-07 |
2023-08-12 |
rat |
| S Y Chen, R I Burger, M E Reit. Extracellular dopamine in the rat ventral tegmental area and nucleus accumbens following ventral tegmental infusion of cocaine. Brain research. vol 729. issue 2. 1997-02-07. PMID:8877004. |
infusion of cocaine (10, 100, 1000 mm) into the ventral tegmental area gradually increased extracellular dopamine to 164, 329 and 991% of baseline in the ventral tegmental area, but reduced dopamine to 76, 47 and 38% of baseline in the nucleus acumbens. |
1997-02-07 |
2023-08-12 |
rat |
| A Imperato, M C Obinu, M A Casu, M S Mascia, G Carta, G L Gess. Chronic morphine increases hippocampal acetylcholine release: possible relevance in drug dependence. European journal of pharmacology. vol 302. issue 1-3. 1997-02-06. PMID:8790987. |
previous studies have shown that cocaine and amphetamine stimulate acetylcholine release in the hippocampus via an action of endogenously released dopamine on dopamine d1 and d2 receptors. |
1997-02-06 |
2023-08-12 |
Not clear |
| J Gelernter, D Vandenbergh, S D Kruger, D L Pauls, R Kurlan, A J Pakstis, K K Kidd, G Uh. The dopamine transporter protein gene (SLC6A3): primary linkage mapping and linkage studies in Tourette syndrome. Genomics. vol 30. issue 3. 1997-02-06. PMID:8825631. |
the dopamine transporter, the molecule responsible for presynaptic reuptake of dopamine and a major site of action of psychostimulant drugs, including cocaine, is encoded by locus slc6a3 (alias dat1). |
1997-02-06 |
2023-08-12 |
Not clear |
| S D Glick, M E Kuehne, I M Maisonneuve, U K Bandarage, H H Molinar. 18-Methoxycoronaridine, a non-toxic iboga alkaloid congener: effects on morphine and cocaine self-administration and on mesolimbic dopamine release in rats. Brain research. vol 719. issue 1-2. 1997-02-04. PMID:8782860. |
18-methoxycoronaridine, a non-toxic iboga alkaloid congener: effects on morphine and cocaine self-administration and on mesolimbic dopamine release in rats. |
1997-02-04 |
2023-08-12 |
rat |
| S Kitayama, K Morita, T Doh. Cocaine inhibits the release of MPP+ but not dopamine through the rat dopamine transporter. European journal of pharmacology. vol 309. issue 1. 1997-01-31. PMID:8864700. |
cocaine inhibits the release of mpp+ but not dopamine through the rat dopamine transporter. |
1997-01-31 |
2023-08-12 |
rat |