| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| W S Choi, O K Rønneklei. Effects of in utero cocaine exposure on the expression of mRNAS encoding the dopamine transporter and the D1, D2 and D5 dopamine receptor subtypes in fetal rhesus monkey. Brain research. Developmental brain research. vol 96. issue 1-2. 1997-03-11. PMID:8922687. |
the effects of in utero cocaine exposure on the development of the mrnas encoding the dopamine transporter (dat) and the d1, d2 and d5 dopamine receptor subtypes were determined in fetal monkey brains at day 45 and day 60 of gestation. |
1997-03-11 |
2023-08-12 |
human |
| W S Choi, O K Rønneklei. Effects of in utero cocaine exposure on the expression of mRNAS encoding the dopamine transporter and the D1, D2 and D5 dopamine receptor subtypes in fetal rhesus monkey. Brain research. Developmental brain research. vol 96. issue 1-2. 1997-03-11. PMID:8922687. |
in utero cocaine exposure caused a significant increase in dopamine d1, d2 and d5 receptor subtype mrnas in the frontal cortex/striatal area of day 60 fetal monkeys. |
1997-03-11 |
2023-08-12 |
human |
| N D Volkow, Y S Ding, J S Fowler, G J Wan. Cocaine addiction: hypothesis derived from imaging studies with PET. Journal of addictive diseases. vol 15. issue 4. 1997-03-11. PMID:8943582. |
analysis of the behavior of cocaine in the human brain with positron emission tomography reveals that it is not only its affinity for the dopamine transporter that gives it its unique properties but also its fast pharmacokinetics. |
1997-03-11 |
2023-08-12 |
human |
| M J Kree. Cocaine, dopamine and the endogenous opioid system. Journal of addictive diseases. vol 15. issue 4. 1997-03-11. PMID:8943583. |
cocaine, dopamine and the endogenous opioid system. |
1997-03-11 |
2023-08-12 |
Not clear |
| M J Kree. Cocaine, dopamine and the endogenous opioid system. Journal of addictive diseases. vol 15. issue 4. 1997-03-11. PMID:8943583. |
fundamental studies from many laboratories including our own have shown that cocaine has profound effects on dopaminergic function, primarily from its well-established primary action of blocking the reuptake of dopamine from the synaptic cleft, an action of cocaine directed at the specific dopamine transporter. |
1997-03-11 |
2023-08-12 |
Not clear |
| A Imperato, M C Obinu, M S Mascia, M A Casu, A Zocchi, S Cabib, S Puglisi-Allegr. Strain-dependent effects of dopamine agonists on acetylcholine release in the hippocampus: an in vivo study in mice. Neuroscience. vol 70. issue 3. 1997-03-06. PMID:9045078. |
the effects of selective d1 or d2 dopamine receptor agonists and the indirect dopamine agonist cocaine on hippocampal acetylcholine release in mice of the c57bl/6 and dba/2 inbred strains were investigated using intracerebral microdialysis. |
1997-03-06 |
2023-08-12 |
mouse |
| E Friedman, E Yadin, H Y Wan. Effect of prenatal cocaine on dopamine receptor-G protein coupling in mesocortical regions of the rabbit brain. Neuroscience. vol 70. issue 3. 1997-03-06. PMID:9045085. |
effect of prenatal cocaine on dopamine receptor-g protein coupling in mesocortical regions of the rabbit brain. |
1997-03-06 |
2023-08-12 |
rabbit |
| E Friedman, E Yadin, H Y Wan. Effect of prenatal cocaine on dopamine receptor-G protein coupling in mesocortical regions of the rabbit brain. Neuroscience. vol 70. issue 3. 1997-03-06. PMID:9045085. |
the effects of in utero exposure to cocaine on dopamine receptors in the frontal and cingulate areas of the developing rabbit cortex were assessed by examining receptor-mediated stimulations in gtp binding to alpha-subunits of g proteins. |
1997-03-06 |
2023-08-12 |
rabbit |
| E Friedman, E Yadin, H Y Wan. Effect of prenatal cocaine on dopamine receptor-G protein coupling in mesocortical regions of the rabbit brain. Neuroscience. vol 70. issue 3. 1997-03-06. PMID:9045085. |
furthermore, prenatal cocaine did not affect [3h]8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1h-3-benzazepin-7- olhemimaleate binding to cortical d1 dopamine receptors. |
1997-03-06 |
2023-08-12 |
rabbit |
| J Z Little, T J Teyle. In utero cocaine exposure decreases dopamine D1 receptor modulation of hippocampal long-term potentiation in the rabbit. Neuroscience letters. vol 215. issue 3. 1997-02-28. PMID:8899737. |
in utero cocaine exposure decreases dopamine d1 receptor modulation of hippocampal long-term potentiation in the rabbit. |
1997-02-28 |
2023-08-12 |
rabbit |
| J Z Little, T J Teyle. In utero cocaine exposure decreases dopamine D1 receptor modulation of hippocampal long-term potentiation in the rabbit. Neuroscience letters. vol 215. issue 3. 1997-02-28. PMID:8899737. |
disturbances of behavior and cellular physiology have been associated with prenatal cocaine exposure and are related to changes in dopamine transmission. |
1997-02-28 |
2023-08-12 |
rabbit |
| T Belej, D Manji, S Sioutis, H M Barros, J N Nobreg. Changes in serotonin and norepinephrine uptake sites after chronic cocaine: pre- vs. post-withdrawal effects. Brain research. vol 736. issue 1-2. 1997-02-26. PMID:8930335. |
although acute cocaine is a strong reuptake inhibitor at dopamine (da), norepinephrine (ne) and serotonin (5-ht) synapses, the effects of chronic cocaine on 5-ht and ne transporters have received less attention than its effects on da transporters. |
1997-02-26 |
2023-08-12 |
rat |
| J Harvey, M G Lace. Endogenous and exogenous dopamine depress EPSCs in rat nucleus accumbens in vitro via D1 receptors activation. The Journal of physiology. vol 492 ( Pt 1). 1997-02-21. PMID:8730590. |
epscs were reversibly depressed by the dopamine mimetic psychostimulants cocaine (1-20 microm) and amphetamine (10-30 microm) by 40 +/- 16 and 62 +/- 9%, respectively, but only in about half of the cells tested (11/23 and 6/13, respectively). |
1997-02-21 |
2023-08-12 |
rat |
| J Harvey, M G Lace. Endogenous and exogenous dopamine depress EPSCs in rat nucleus accumbens in vitro via D1 receptors activation. The Journal of physiology. vol 492 ( Pt 1). 1997-02-21. PMID:8730590. |
no discernable effects of dopamine, skf 81297a, skf 38393, quinpirole, cocaine or amphetamine were observed on membrane conductance or holding current (at holding potentials of -80 to -90 mv), suggesting that the depression of the epsc was solely due to an action on presynaptic d1 receptors. |
1997-02-21 |
2023-08-12 |
rat |
| T A Grady, A Broocks, S K Canter, T A Pigott, B Dubbert, J L Hill, D L Murph. Biological and behavioral responses to D-amphetamine, alone and in combination with the serotonin3 receptor antagonist ondansetron, in healthy volunteers. Psychiatry research. vol 64. issue 1. 1997-02-21. PMID:8888359. |
evidence that serotonin3 (5-hydroxytryptamine3, 5-ht3) antagonists attenuate behavioral responses to d-amphetamine and cocaine suggests that 5-ht3 receptors modulate brain dopamine in animals. |
1997-02-21 |
2023-08-12 |
human |
| R M Craft, J A Stratman. Discriminative stimulus effects of cocaine in female versus male rats. Drug and alcohol dependence. vol 42. issue 1. 1997-02-21. PMID:8889401. |
the dopamine antagonist fluphenazine blocked the discriminative stimulus effects of cocaine to approximately the same extent in both sexes. |
1997-02-21 |
2023-08-12 |
rat |
| B Geter-Douglass, A L Rile. Dopamine D1/D2 antagonist combinations as antagonists of the discriminative stimulus effects of cocaine. Pharmacology, biochemistry, and behavior. vol 54. issue 2. 1997-02-12. PMID:8743607. |
dopamine d1/d2 antagonist combinations as antagonists of the discriminative stimulus effects of cocaine. |
1997-02-12 |
2023-08-12 |
rat |
| B Geter-Douglass, A L Rile. Dopamine D1/D2 antagonist combinations as antagonists of the discriminative stimulus effects of cocaine. Pharmacology, biochemistry, and behavior. vol 54. issue 2. 1997-02-12. PMID:8743607. |
although data suggest that the dopaminergic system mediates the discriminative stimulus effects of cocaine, neither selective d1 or d2 dopamine agonists nor selective d1 or d2 antagonists substitute reliably for or consistently block these effects. |
1997-02-12 |
2023-08-12 |
rat |
| L Koetzner, A L Riley, J R Glow. Discriminative stimulus effects of dopaminergic agents in rhesus monkeys. Pharmacology, biochemistry, and behavior. vol 54. issue 2. 1997-02-12. PMID:8743617. |
recent reports have shown that treatment with dopamine reuptake inhibitors can selectively decrease responding maintained by low doses of cocaine in rhesus monkeys. |
1997-02-12 |
2023-08-12 |
monkey |
| L Koetzner, A L Riley, J R Glow. Discriminative stimulus effects of dopaminergic agents in rhesus monkeys. Pharmacology, biochemistry, and behavior. vol 54. issue 2. 1997-02-12. PMID:8743617. |
one behavioral effect that dopamine reuptake inhibitors and cocaine share is their ability to serve as a discriminative stimulus. |
1997-02-12 |
2023-08-12 |
monkey |