Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
M A De Souza Silva, C Mattern, R Häcker, P J Nogueira, J P Huston, R K Schwartin. Intranasal administration of the dopaminergic agonists L-DOPA, amphetamine, and cocaine increases dopamine activity in the neostriatum: a microdialysis study in the rat. Journal of neurochemistry. vol 68. issue 1. 1997-01-27. PMID:8978730. |
intranasal administration of the dopaminergic agonists l-dopa, amphetamine, and cocaine increases dopamine activity in the neostriatum: a microdialysis study in the rat. |
1997-01-27 |
2023-08-12 |
rat |
E A Kiyatkin, E A Stei. Conditioned changes in nucleus accumbens dopamine signal established by intravenous cocaine in rats. Neuroscience letters. vol 211. issue 2. 1997-01-23. PMID:8830847. |
conditioned changes in nucleus accumbens dopamine signal established by intravenous cocaine in rats. |
1997-01-23 |
2023-08-12 |
rat |
E A Kiyatkin, E A Stei. Conditioned changes in nucleus accumbens dopamine signal established by intravenous cocaine in rats. Neuroscience letters. vol 211. issue 2. 1997-01-23. PMID:8830847. |
to explore the role of cocaine-induced conditioning in the regulation of mesolimbic dopamine (da) activity, high-speed chronoamperometry with nafion-coated carbon fiber electrodes was used to measure changes in nucleus accumbens (nac) da-dependent signal induced by a light stimulus previously paired and not paired with intravenous cocaine (0.85 mg/kg per injection), and cocaine injections paired and not paired with light. |
1997-01-23 |
2023-08-12 |
rat |
L Cervo, L Pozzi, R Samani. 5-HT3 receptor antagonists do not modify cocaine place conditioning or the rise in extracellular dopamine in the nucleus accumbens of rats. Pharmacology, biochemistry, and behavior. vol 55. issue 1. 1997-01-23. PMID:8870035. |
5-ht3 receptor antagonists do not modify cocaine place conditioning or the rise in extracellular dopamine in the nucleus accumbens of rats. |
1997-01-23 |
2023-08-12 |
rat |
L Cervo, L Pozzi, R Samani. 5-HT3 receptor antagonists do not modify cocaine place conditioning or the rise in extracellular dopamine in the nucleus accumbens of rats. Pharmacology, biochemistry, and behavior. vol 55. issue 1. 1997-01-23. PMID:8870035. |
at 0.1 mg/kg sc ondansetron did not modify the increase of extracellular dopamine caused by 10 mg/kg cocaine in the nucleus accumbens. |
1997-01-23 |
2023-08-12 |
rat |
E Tirelli, J M Witki. Pharmacological characterization of the enhancement of apomorphine-induced gnawing in mice by cocaine. Pharmacology, biochemistry, and behavior. vol 55. issue 1. 1997-01-23. PMID:8870049. |
rather, this effect may be due to blockade of dopamine uptake and/or the local anesthetic actions of cocaine. |
1997-01-23 |
2023-08-12 |
mouse |
W J Houlihan, J W Boja, V A Parrino, T A Kopajtic, M J Kuha. Halogenated mazindol analogs as potential inhibitors of the cocaine binding site at the dopamine transporter. Journal of medicinal chemistry. vol 39. issue 25. 1997-01-23. PMID:8960553. |
halogenated mazindol analogs as potential inhibitors of the cocaine binding site at the dopamine transporter. |
1997-01-23 |
2023-08-12 |
rat |
M S Kleven, W Koe. Differential effects of direct and indirect dopamine agonists on eye blink rate in cynomolgus monkeys. The Journal of pharmacology and experimental therapeutics. vol 279. issue 3. 1997-01-23. PMID:8968343. |
spontaneous eye blink rate was assessed in cynomolgus monkeys treated intramuscularly with the high-efficacy dopamine (da) agonists, (-)-apomorphine, naxagolide, pd 128,907, 2-(n-phenylethyl-n-propyl)amino-5-hydroxytetralin (+/-)-ppht, quinpirole, skf 81297 and skf 82958; the low-efficacy da agonists, (-)-3-ppp, roxindole, sdz 208-912, skf 75670 and terguride; and the indirect da agonists, d-amphetamine, cocaine, gbr 12935 and methylphenidate. |
1997-01-23 |
2023-08-12 |
monkey |
P D Mozley, H J Kim, R C Gur, K Tatsch, L R Muenz, W T McElgin, M P Kung, M Mu, A M Myers, H F Kun. Iodine-123-IPT SPECT imaging of CNS dopamine transporters: nonlinear effects of normal aging on striatal uptake values. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 37. issue 12. 1997-01-23. PMID:8970515. |
iodine-123-labeled ipt (n-(3-iodopropen-2-yl)-2 beta-carbomethoxy-3 beta-(4-chlorophenyl)tropane) is an analog of cocaine that selectively binds the presynaptic dopamine transporter. |
1997-01-23 |
2023-08-12 |
Not clear |
G Palladini, S Ruggeri, F Stocchi, M F De Pandis, G Venturini, V Margott. A pharmacological study of cocaine activity in planaria. Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology. vol 115. issue 1. 1997-01-23. PMID:8983168. |
the dose-related effects of cocaine on planaria motility and the response to cocaine treatment associated with the administration of specific d1 or d2 dopamine agonists and antagonists were investigated. |
1997-01-23 |
2023-08-12 |
Not clear |
b' A Kankaanp\\xc3\\xa4\\xc3\\xa4, P Lillsunde, M Ruotsalainen, L Ahtee, T Sepp\\xc3\\xa2l\\xc3\\xa. 5-HT3 receptor antagonist MDL 72222 dose-dependently attenuates cocaine- and amphetamine-induced elevations of extracellular dopamine in the nucleus accumbens and the dorsal striatum. Pharmacology & toxicology. vol 78. issue 5. 1997-01-21. PMID:8737967.' |
cocaine elevated extracellular dopamine in the nucleus accumbens and to a lesser extent in the dorsal striatum, but it did not affect dopamine metabolites, 3,4-dihydroxyphenylacetic acid (dopac) and homovanillic acid. |
1997-01-21 |
2023-08-12 |
rat |
b' A Kankaanp\\xc3\\xa4\\xc3\\xa4, P Lillsunde, M Ruotsalainen, L Ahtee, T Sepp\\xc3\\xa2l\\xc3\\xa. 5-HT3 receptor antagonist MDL 72222 dose-dependently attenuates cocaine- and amphetamine-induced elevations of extracellular dopamine in the nucleus accumbens and the dorsal striatum. Pharmacology & toxicology. vol 78. issue 5. 1997-01-21. PMID:8737967.' |
the different potencies of the interactions of the 5-ht3 receptor antagonist with cocaine and amphetamine could be related to the different mechanisms by which these drugs primarily elevate extracellular dopamine. |
1997-01-21 |
2023-08-12 |
rat |
b' B Przew\\xc5\\x82ocka, W Laso\\xc5\\x8. Adaptive changes in the proenkephalin and D2 dopamine receptor mRNA expression after chronic cocaine in the nucleus accumbens and striatum of the rat. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 5. issue 4. 1997-01-17. PMID:8998398.' |
hence, these data provide further evidence for the significance of the penk and dopamine systems in the neurochemical mechanism of cocaine. |
1997-01-17 |
2023-08-12 |
rat |
B A Mattingly, J K Rowlett, T Ellison, K Ras. Cocaine-induced behavioral sensitization: effects of haloperidol and SCH 23390 treatments. Pharmacology, biochemistry, and behavior. vol 53. issue 3. 1997-01-15. PMID:8866944. |
these findings suggest that cocaine-induced behavioral sensitization may develop as a result of repeated dopamine d1- or d2-type receptor stimulation, and that brief dopamine antagonist treatments enhance subsequent behavioral sensitivity to cocaine. |
1997-01-15 |
2023-08-12 |
rat |
X H Wang, P Levitt, A O'Brien Jenkins, E H Murph. Normal development of tyrosine hydroxylase and serotonin immunoreactive fibers innervating anterior cingulate cortex and visual cortex in rabbits exposed prenatally to cocaine. Brain research. vol 715. issue 1-2. 1997-01-14. PMID:8739642. |
the interactions of cocaine with the dopamine, norepinephrine and serotonin systems makes each a potential candidate for influencing these developmental effects. |
1997-01-14 |
2023-08-12 |
Not clear |
R Weissenborn, V Deroche, G F Koob, F Weis. Effects of dopamine agonists and antagonists on cocaine-induced operant responding for a cocaine-associated stimulus. Psychopharmacology. vol 126. issue 4. 1997-01-10. PMID:8878347. |
the present study examined the effects of receptor subtype-selective dopamine agonists and antagonists on (i) cocaine-induced responding for a cocaine-associated stimulus and (ii) on responding for food and cocaine reinforcement. |
1997-01-10 |
2023-08-12 |
rat |
S R Jones, T H Lee, R M Wightman, E H Ellinwoo. Effects of intermittent and continuous cocaine administration on dopamine release and uptake regulation in the striatum: in vitro voltammetric assessment. Psychopharmacology. vol 126. issue 4. 1997-01-10. PMID:8878349. |
effects of intermittent and continuous cocaine administration on dopamine release and uptake regulation in the striatum: in vitro voltammetric assessment. |
1997-01-10 |
2023-08-12 |
rat |
S R Jones, T H Lee, R M Wightman, E H Ellinwoo. Effects of intermittent and continuous cocaine administration on dopamine release and uptake regulation in the striatum: in vitro voltammetric assessment. Psychopharmacology. vol 126. issue 4. 1997-01-10. PMID:8878349. |
following a 7-day withdrawal period, we examined the effects of these two dosing regimens on: (1) baseline dopamine efflux and uptake following single-pulse electrical stimulation, (2) inhibition of uptake by cocaine; and (3) inhibition of efflux by autoreceptor activation. |
1997-01-10 |
2023-08-12 |
rat |
S R Jones, T H Lee, R M Wightman, E H Ellinwoo. Effects of intermittent and continuous cocaine administration on dopamine release and uptake regulation in the striatum: in vitro voltammetric assessment. Psychopharmacology. vol 126. issue 4. 1997-01-10. PMID:8878349. |
in the absence of pharmacological agents, no group differences were found in the amount of baseline dopamine released or in the uptake kinetics; the potency of bath-applied cocaine (0.03-60 microm) in inhibiting the uptake was also unaltered in either group. |
1997-01-10 |
2023-08-12 |
rat |
C L Monitto, P Feuer, M O'Rourke, L Shaw, C D Kurt. Effect of dopamine antagonism on the behavioral and hemodynamic responses to cocaine in piglets. Biology of the neonate. vol 70. issue 1. 1997-01-09. PMID:8853847. |
effect of dopamine antagonism on the behavioral and hemodynamic responses to cocaine in piglets. |
1997-01-09 |
2023-08-12 |
Not clear |