| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L D Middaugh, K K McGroarty, C H Groseclose, B Adinof. Cocaine discrimination: relationship to local anesthetics and monoamine uptake inhibitors in C57BL/6 mice. Psychopharmacology. vol 136. issue 1. 1998-05-21. PMID:9537681. |
these experiments emphasize the importance of the dopamine transporter in mediating the discriminative stimulus effects of cocaine in c57 mice. |
1998-05-21 |
2023-08-12 |
mouse |
| H Wayment, S M Meiergerd, J O Schen. Relationships between the catechol substrate binding site and amphetamine, cocaine, and mazindol binding sites in a kinetic model of the striatal transporter of dopamine in vitro. Journal of neurochemistry. vol 70. issue 5. 1998-05-18. PMID:9572278. |
relationships between the catechol substrate binding site and amphetamine, cocaine, and mazindol binding sites in a kinetic model of the striatal transporter of dopamine in vitro. |
1998-05-18 |
2023-08-12 |
Not clear |
| P M Kunko, D French, S Izenwasse. Alterations in locomotor activity during chronic cocaine administration: effect on dopamine receptors and interaction with opioids. The Journal of pharmacology and experimental therapeutics. vol 285. issue 1. 1998-05-12. PMID:9536022. |
alterations in locomotor activity during chronic cocaine administration: effect on dopamine receptors and interaction with opioids. |
1998-05-12 |
2023-08-12 |
Not clear |
| P M Kunko, D French, S Izenwasse. Alterations in locomotor activity during chronic cocaine administration: effect on dopamine receptors and interaction with opioids. The Journal of pharmacology and experimental therapeutics. vol 285. issue 1. 1998-05-12. PMID:9536022. |
thus, continuous cocaine administration produces a rapid sensitization that is lost over the course of the treatment period, yet does not produce any immediate alterations in dopamine receptors or regulation of adenylyl cyclase. |
1998-05-12 |
2023-08-12 |
Not clear |
| D R Woolfolk, S G Holtzma. mu-, delta- and kappa-opioid receptor agonists do not alter the discriminative stimulus effects of cocaine or d-amphetamine in rats. Drug and alcohol dependence. vol 48. issue 3. 1998-05-04. PMID:9449020. |
opioid receptor agonists can modulate the activity of dopamine neurons and could therefore, modify the behavioral effects of drugs that act through the dopamine systems, such as d-amphetamine and cocaine. |
1998-05-04 |
2023-08-12 |
rat |
| M B Bowers, R T Malison, J P Seibyl, T R Koste. Plasma homovanillic acid and the dopamine transporter during cocaine withdrawal. Biological psychiatry. vol 43. issue 4. 1998-04-30. PMID:9513737. |
plasma homovanillic acid and the dopamine transporter during cocaine withdrawal. |
1998-04-30 |
2023-08-12 |
human |
| M B Bowers, R T Malison, J P Seibyl, T R Koste. Plasma homovanillic acid and the dopamine transporter during cocaine withdrawal. Biological psychiatry. vol 43. issue 4. 1998-04-30. PMID:9513737. |
we used single photon emission tomography (spect) assessment of the dopamine (da) transporter for comparison with plasma hva in subjects at varying stages of abstinence from cocaine. |
1998-04-30 |
2023-08-12 |
human |
| R B Rothman, M L Silverthorn, J R Glowa, D Matecka, K C Rice, F I Carroll, J S Partilla, G R Uhl, D J Vandenbergh, C M Dersc. Studies of the biogenic amine transporters. VII. Characterization of a novel cocaine binding site identified with [125I]RTI-55 in membranes prepared from human, monkey and guinea pig caudate. Synapse (New York, N.Y.). vol 28. issue 4. 1998-04-30. PMID:9517841. |
[125i]rti-55 is a cocaine analog with high affinity for dopamine (da) and serotonin (5-ht) transporters. |
1998-04-30 |
2023-08-12 |
human |
| M P Epping-Jordan, A Markou, G F Koo. The dopamine D-1 receptor antagonist SCH 23390 injected into the dorsolateral bed nucleus of the stria terminalis decreased cocaine reinforcement in the rat. Brain research. vol 784. issue 1-2. 1998-04-30. PMID:9518570. |
the dopamine d-1 receptor antagonist sch 23390 injected into the dorsolateral bed nucleus of the stria terminalis decreased cocaine reinforcement in the rat. |
1998-04-30 |
2023-08-12 |
rat |
| M P Epping-Jordan, A Markou, G F Koo. The dopamine D-1 receptor antagonist SCH 23390 injected into the dorsolateral bed nucleus of the stria terminalis decreased cocaine reinforcement in the rat. Brain research. vol 784. issue 1-2. 1998-04-30. PMID:9518570. |
these results suggest a role for d-1 dopamine receptors in the dlbnst in the reinforcing properties of self-administered cocaine, and also support the hypothesis that d-1 dopamine receptors in the 'extended amygdala' may play a significant role in cocaine self-administration. |
1998-04-30 |
2023-08-12 |
rat |
| Y L Hurd, A McGregor, M Ponté. In vivo amygdala dopamine levels modulate cocaine self-administration behaviour in the rat: D1 dopamine receptor involvement. The European journal of neuroscience. vol 9. issue 12. 1998-04-24. PMID:9517459. |
in vivo amygdala dopamine levels modulate cocaine self-administration behaviour in the rat: d1 dopamine receptor involvement. |
1998-04-24 |
2023-08-12 |
rat |
| Y L Hurd, A McGregor, M Ponté. In vivo amygdala dopamine levels modulate cocaine self-administration behaviour in the rat: D1 dopamine receptor involvement. The European journal of neuroscience. vol 9. issue 12. 1998-04-24. PMID:9517459. |
nucleus accumbens dopamine is often hypothesized as the critical factor for modulating cocaine self-administration. |
1998-04-24 |
2023-08-12 |
rat |
| Y L Hurd, A McGregor, M Ponté. In vivo amygdala dopamine levels modulate cocaine self-administration behaviour in the rat: D1 dopamine receptor involvement. The European journal of neuroscience. vol 9. issue 12. 1998-04-24. PMID:9517459. |
in the current study we examined the extent to which dopamine in the amygdala could contribute to cocaine intake behaviour and modify nucleus accumbens dopamine levels. |
1998-04-24 |
2023-08-12 |
rat |
| Y L Hurd, A McGregor, M Ponté. In vivo amygdala dopamine levels modulate cocaine self-administration behaviour in the rat: D1 dopamine receptor involvement. The European journal of neuroscience. vol 9. issue 12. 1998-04-24. PMID:9517459. |
although cocaine induced similar profiles of dopamine overflow in the two mesolimbic areas, in the nucleus accumbens the latency of the dopaminergic response was shorter (three- to four-fold) during both initiation and termination of the cocaine self-administration session than in the amygdala. |
1998-04-24 |
2023-08-12 |
rat |
| Y L Hurd, A McGregor, M Ponté. In vivo amygdala dopamine levels modulate cocaine self-administration behaviour in the rat: D1 dopamine receptor involvement. The European journal of neuroscience. vol 9. issue 12. 1998-04-24. PMID:9517459. |
despite achieving a stable self-regulated pattern of cocaine intake and high dopamine concentrations in the nucleus accumbens, a unilateral injection of the d1 receptor antagonist sch 23390 (0.5 or 1.5 microg) into the amygdala was still able to increase the rate of cocaine intake. |
1998-04-24 |
2023-08-12 |
rat |
| Y L Hurd, A McGregor, M Ponté. In vivo amygdala dopamine levels modulate cocaine self-administration behaviour in the rat: D1 dopamine receptor involvement. The European journal of neuroscience. vol 9. issue 12. 1998-04-24. PMID:9517459. |
this behavioural effect was accompanied by a dose-dependent increase in nucleus accumbens dopamine levels; at the highest sch 23390 concentration cocaine intake was increased by 400% and dopamine levels were potentiated by an additional 400%. |
1998-04-24 |
2023-08-12 |
rat |
| Y L Hurd, A McGregor, M Ponté. In vivo amygdala dopamine levels modulate cocaine self-administration behaviour in the rat: D1 dopamine receptor involvement. The European journal of neuroscience. vol 9. issue 12. 1998-04-24. PMID:9517459. |
altogether these results point to a significant contribution of in vivo amygdala d1 dopamine transmission to cocaine self-administration behaviour. |
1998-04-24 |
2023-08-12 |
rat |
| M B Gatch, S S Negus, N K Mell. Antinociceptive effects of monoamine reuptake inhibitors administered alone or in combination with mu opioid agonists in rhesus monkeys. Psychopharmacology. vol 135. issue 1. 1998-04-22. PMID:9489939. |
cocaine, which non-selectively blocks the reuptake of the monoamines serotonin, dopamine and norepinephrine, produces weak antinociceptive effects and increases the antinociceptive effects of low- to intermediate-efficacy mu opioid agonists in rhesus monkeys. |
1998-04-22 |
2023-08-12 |
monkey |
| S F Lieske, B Yang, M E Eldefrawi, A D MacKerell, J Wrigh. (-)-3 beta-Substituted ecgonine methyl esters as inhibitors for cocaine binding and dopamine uptake. Journal of medicinal chemistry. vol 41. issue 6. 1998-04-16. PMID:9526561. |
(-)-3 beta-substituted ecgonine methyl esters as inhibitors for cocaine binding and dopamine uptake. |
1998-04-16 |
2023-08-12 |
rat |
| M S Kleven, W Koe. Discriminative stimulus properties of cocaine: enhancement by monoamine reuptake blockers. The Journal of pharmacology and experimental therapeutics. vol 284. issue 3. 1998-04-09. PMID:9495862. |
in this study we examined the ability of compounds varying in their in vitro potencies as inhibitors of dopamine (da), norepinephrine (ne) or serotonin (5-ht) reuptake to enhance the discriminative stimulus (ds) effects of cocaine. |
1998-04-09 |
2023-08-12 |
rat |