| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| W Y Gao, T H Lee, G R King, E H Ellinwoo. Alterations in baseline activity and quinpirole sensitivity in putative dopamine neurons in the substantia nigra and ventral tegmental area after withdrawal from cocaine pretreatment. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 18. issue 3. 1998-04-02. PMID:9471119. |
alterations in baseline activity and quinpirole sensitivity in putative dopamine neurons in the substantia nigra and ventral tegmental area after withdrawal from cocaine pretreatment. |
1998-04-02 |
2023-08-12 |
rat |
| W Y Gao, T H Lee, G R King, E H Ellinwoo. Alterations in baseline activity and quinpirole sensitivity in putative dopamine neurons in the substantia nigra and ventral tegmental area after withdrawal from cocaine pretreatment. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 18. issue 3. 1998-04-02. PMID:9471119. |
using in vivo single-unit recording, we compared in rats the-effects of continuous infusion and once-a-day injections of cocaine on the activity of single putative dopamine neurons in the substantia nigra and ventral tegmental area. |
1998-04-02 |
2023-08-12 |
rat |
| S R Tella, S R Goldber. Monoamine transporter and sodium channel mechanisms in the rapid pressor response to cocaine. Pharmacology, biochemistry, and behavior. vol 59. issue 2. 1998-03-31. PMID:9476974. |
the present data suggest that the inhibition of dopamine, norepinephrine, or serotonin transporter functions, either alone or in combination, does not mediate the rapid pressor response to cocaine. |
1998-03-31 |
2023-08-12 |
rat |
| T Okada, M Fujita, S Shimada, K Sato, P Schloss, Y Watanabe, Y Itoh, M Tohyama, T Nishimur. Assessment of affinities of beta-CIT, beta-CIT-FE, and beta-CIT-FP for monoamine transporters permanently expressed in cell lines. Nuclear medicine and biology. vol 25. issue 1. 1998-03-26. PMID:9466362. |
we investigated the effects of three cocaine analogs, beta-cit (2-beta-carbomethoxy-3-beta-(4-iodophenyl)-tropane), beta-cit-fe (2-beta-carbomethoxy-3-beta-(4-iodophenyl)-n-(2.fluoroethyl)-nortropa ne), and beta-cit-fp (2-beta-carbomethoxy-3-beta-(4-iodophenyl)-n-(3-fluoropropyl)-n ortropane), on the uptake of [3h]dopamine(da), serotonin(5-ht), and 1-norepinephrine (ne) using cell lines permanently expressing da, 5-ht, and ne transporters, respectively, to determine their affinities for these three transporters. |
1998-03-26 |
2023-08-12 |
Not clear |
| C L Coulter, H K Happe, L C Murri. Dopamine transporter development in postnatal rat striatum: an autoradiographic study with [3H]WIN 35,428. Brain research. Developmental brain research. vol 104. issue 1-2. 1998-03-20. PMID:9466707. |
the dopamine transporter mediates the reinforcing effects of cocaine, thus playing a central role in human cocaine addiction, and perhaps providing the mechanism for inducing the effects of prenatal cocaine exposure. |
1998-03-20 |
2023-08-12 |
human |
| C L Coulter, H K Happe, L C Murri. Dopamine transporter development in postnatal rat striatum: an autoradiographic study with [3H]WIN 35,428. Brain research. Developmental brain research. vol 104. issue 1-2. 1998-03-20. PMID:9466707. |
[3h]win 35,428 is a cocaine analog that is useful for studying the distribution and density of the dopamine transporter in striatum and other brain regions. |
1998-03-20 |
2023-08-12 |
human |
| Y Fang, A Janowsky, O K Rønneklei. Cocaine exposure in fetal rhesus monkey: consequences for dopamine D1- and D2-like receptor binding densities. Brain research. Developmental brain research. vol 104. issue 1-2. 1998-03-20. PMID:9466719. |
cocaine exposure in fetal rhesus monkey: consequences for dopamine d1- and d2-like receptor binding densities. |
1998-03-20 |
2023-08-12 |
monkey |
| Y Fang, A Janowsky, O K Rønneklei. Cocaine exposure in fetal rhesus monkey: consequences for dopamine D1- and D2-like receptor binding densities. Brain research. Developmental brain research. vol 104. issue 1-2. 1998-03-20. PMID:9466719. |
previously we found that dopamine d1-, d2- and d5-receptor mrna subtypes are significantly increased in the rostral forebrain of fetal monkeys exposed to cocaine. |
1998-03-20 |
2023-08-12 |
monkey |
| Y Fang, A Janowsky, O K Rønneklei. Cocaine exposure in fetal rhesus monkey: consequences for dopamine D1- and D2-like receptor binding densities. Brain research. Developmental brain research. vol 104. issue 1-2. 1998-03-20. PMID:9466719. |
the present results provide further support for the hypothesis that gestational cocaine exposure causes reduced synthesis and release of dopamine which leads to dopamine d1- and d2-receptor up-regulation in dopamine target neurons. |
1998-03-20 |
2023-08-12 |
monkey |
| P Soares-Da-Silva, M P Serrão, M A Vieira-Coelh. Apical and basolateral uptake and intracellular fate of dopamine precursor L-dopa in LLC-PK1 cells. The American journal of physiology. vol 274. issue 2. 1998-03-17. PMID:9486218. |
the apical and basal outward transfers of dopamine were insensitive to cocaine (10 and 30 microm) and gbr-12909 (1 and 3 microm). |
1998-03-17 |
2023-08-12 |
Not clear |
| P Soares-Da-Silva, M P Serrão, M A Vieira-Coelh. Apical and basolateral uptake and intracellular fate of dopamine precursor L-dopa in LLC-PK1 cells. The American journal of physiology. vol 274. issue 2. 1998-03-17. PMID:9486218. |
however, both cocaine (10, 30, or 100 microm) and gbr-12909 (1 or 3 microm) were found not to affect the uptake of 100 microm dopamine applied from either the apical or the basal cell border. |
1998-03-17 |
2023-08-12 |
Not clear |
| E J Bilsky, M J Montegut, M L Nichols, L D Rei. CGS 10746B, a novel dopamine release inhibitor, blocks the establishment of cocaine and MDMA conditioned place preferences. Pharmacology, biochemistry, and behavior. vol 59. issue 1. 1998-03-09. PMID:9443558. |
cgs 10746b, a novel dopamine release inhibitor, blocks the establishment of cocaine and mdma conditioned place preferences. |
1998-03-09 |
2023-08-12 |
rat |
| E J Bilsky, M J Montegut, M L Nichols, L D Rei. CGS 10746B, a novel dopamine release inhibitor, blocks the establishment of cocaine and MDMA conditioned place preferences. Pharmacology, biochemistry, and behavior. vol 59. issue 1. 1998-03-09. PMID:9443558. |
here, the effects of doses of cgs 10746b, an agent reported to attenuate the release of dopamine without occupying dopamine receptors, are assessed on cocaine and mdma's ability to produce a cpp. |
1998-03-09 |
2023-08-12 |
rat |
| D W Self, L M Genova, B T Hope, W J Barnhart, J J Spencer, E J Nestle. Involvement of cAMP-dependent protein kinase in the nucleus accumbens in cocaine self-administration and relapse of cocaine-seeking behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 5. 1998-03-04. PMID:9465009. |
camp-dependent protein kinase (pka) in the nucleus accumbens (nac) has been implicated in cocaine addiction because (1) cocaine reinforcement is mediated by dopamine receptors that modulate camp formation, and (2) repeated exposure to cocaine upregulates the camp system in nac neurons. |
1998-03-04 |
2023-08-12 |
human |
| T W Seale, K Avor, S Singh, N Hall, H M Chan, G P Basmadjia. 2'-Substitution of cocaine selectively enhances dopamine and norepinephrine transporter binding. Neuroreport. vol 8. issue 16. 1998-02-26. PMID:9427328. |
2'-substitution of cocaine selectively enhances dopamine and norepinephrine transporter binding. |
1998-02-26 |
2023-08-12 |
rat |
| T W Seale, K Avor, S Singh, N Hall, H M Chan, G P Basmadjia. 2'-Substitution of cocaine selectively enhances dopamine and norepinephrine transporter binding. Neuroreport. vol 8. issue 16. 1998-02-26. PMID:9427328. |
we synthesized 2'-oh-, 2'-f- and 2'-acetoxy-cocaines and compared their binding potencies for rat dopamine, norepinephrine and 5-hydroxytryptamine transporters to cocaine, 3'-oh-, 4'-oh-, 2'-oh,4'-i-cocaine derivatives, and to the transporter selective ligands win 35,428, nisoxetine and paroxetine. |
1998-02-26 |
2023-08-12 |
rat |
| T W Seale, K Avor, S Singh, N Hall, H M Chan, G P Basmadjia. 2'-Substitution of cocaine selectively enhances dopamine and norepinephrine transporter binding. Neuroreport. vol 8. issue 16. 1998-02-26. PMID:9427328. |
unlike most substitutions, 2'-oh- and 2'-acetoxy-groups increased cocaine's binding potency for the dopamine transporter (10- and 4-fold, respectively). |
1998-02-26 |
2023-08-12 |
rat |
| M E Reith, M Y Li, Q S Ya. Extracellular dopamine, norepinephrine, and serotonin in the ventral tegmental area and nucleus accumbens of freely moving rats during intracerebral dialysis following systemic administration of cocaine and other uptake blockers. Psychopharmacology. vol 134. issue 3. 1998-02-26. PMID:9438681. |
extracellular dopamine, norepinephrine, and serotonin in the ventral tegmental area and nucleus accumbens of freely moving rats during intracerebral dialysis following systemic administration of cocaine and other uptake blockers. |
1998-02-26 |
2023-08-12 |
rat |
| J S Fowler, N D Volkow, J Logan, S J Gatley, N Pappas, P King, Y S Ding, G J Wan. Measuring dopamine transporter occupancy by cocaine in vivo: radiotracer considerations. Synapse (New York, N.Y.). vol 28. issue 2. 1998-02-24. PMID:9450511. |
measuring dopamine transporter occupancy by cocaine in vivo: radiotracer considerations. |
1998-02-24 |
2023-08-12 |
monkey |
| J S Fowler, N D Volkow, J Logan, S J Gatley, N Pappas, P King, Y S Ding, G J Wan. Measuring dopamine transporter occupancy by cocaine in vivo: radiotracer considerations. Synapse (New York, N.Y.). vol 28. issue 2. 1998-02-24. PMID:9450511. |
several recent neuroimaging studies in humans and in monkeys using different radiotracers have reported widely differing values of dopamine transporter (dat) occupancy by doses of cocaine which are perceived as reinforcing by humans. |
1998-02-24 |
2023-08-12 |
monkey |