| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Pulvirenti, C Balducci, M Piercy, G F Koo. Characterization of the effects of the partial dopamine agonist terguride on cocaine self-administration in the rat. The Journal of pharmacology and experimental therapeutics. vol 286. issue 3. 1998-10-08. PMID:9732383. |
characterization of the effects of the partial dopamine agonist terguride on cocaine self-administration in the rat. |
1998-10-08 |
2023-08-12 |
rat |
| L Pulvirenti, C Balducci, M Piercy, G F Koo. Characterization of the effects of the partial dopamine agonist terguride on cocaine self-administration in the rat. The Journal of pharmacology and experimental therapeutics. vol 286. issue 3. 1998-10-08. PMID:9732383. |
dopamine neurotransmission is an important neuropharmacological component of cocaine self-administration in rodents. |
1998-10-08 |
2023-08-12 |
rat |
| R T Malison, E McCance, L L Carpenter, R M Baldwin, J P Seibyl, L H Price, T R Kosten, R B Inni. [123I]beta-CIT SPECT imaging of dopamine transporter availability after mazindol administration in human cocaine addicts. Psychopharmacology. vol 137. issue 4. 1998-10-05. PMID:9676890. |
[123i]beta-cit spect imaging of dopamine transporter availability after mazindol administration in human cocaine addicts. |
1998-10-05 |
2023-08-12 |
human |
| M M Schweri, B R de Costa, K C Ric. Fourphit, an acylating phencyclidine derivative, attenuates cocaine-induced hyperactivity in rats. Pharmacology, biochemistry, and behavior. vol 60. issue 3. 1998-10-02. PMID:9678644. |
these results show that fourphit can antagonize some behavioral actions of cocaine, but these effects are not likely due to covalent modification of the site on the dopamine transporter recognized by cocaine. |
1998-10-02 |
2023-08-12 |
rat |
| J D Steketee, L A Rowe, L J Chandle. The effects of acute and repeated cocaine injections on protein kinase C activity and isoform levels in dopaminergic brain regions. Neuropharmacology. vol 37. issue 3. 1998-10-02. PMID:9681932. |
the present study was designed to assess the effects of acute and repeated cocaine exposure on protein kinase c (pkc) activity and the levels of calcium-dependent isoforms of pkc in mesocorticolimbic and nigrostriatal dopamine brain regions. |
1998-10-02 |
2023-08-12 |
Not clear |
| P M Kanani, P A Guse, W M Smith, A Barnett, E H Ellinwoo. Acute deleterious effects of cocaine on cardiac conduction, hemodynamics, and ventricular fibrillation threshold: effects of interaction with a selective dopamine D1 antagonist SCH 39166. Journal of cardiovascular pharmacology. vol 32. issue 1. 1998-10-01. PMID:9676719. |
acute deleterious effects of cocaine on cardiac conduction, hemodynamics, and ventricular fibrillation threshold: effects of interaction with a selective dopamine d1 antagonist sch 39166. |
1998-10-01 |
2023-08-12 |
Not clear |
| W Gong, D B Neill, J B Justic. GABAergic modulation of ventral pallidal dopamine release studied by in vivo microdialysis in the freely moving rat. Synapse (New York, N.Y.). vol 29. issue 4. 1998-09-24. PMID:9661258. |
cocaine (10 microm) produced a 6.5-fold increase of vp dopamine. |
1998-09-24 |
2023-08-12 |
rat |
| W Gong, D B Neill, J B Justic. GABAergic modulation of ventral pallidal dopamine release studied by in vivo microdialysis in the freely moving rat. Synapse (New York, N.Y.). vol 29. issue 4. 1998-09-24. PMID:9661258. |
neither picrotoxin (200 microm), phaclofen (2,000 microm), nor gaba (20-2,000 microm) altered the response of vp dopamine to locally applied cocaine. |
1998-09-24 |
2023-08-12 |
rat |
| W Gong, D B Neill, J B Justic. GABAergic modulation of ventral pallidal dopamine release studied by in vivo microdialysis in the freely moving rat. Synapse (New York, N.Y.). vol 29. issue 4. 1998-09-24. PMID:9661258. |
however, the effect of gaba on the mesopallidal dopamine system's response to locally applied cocaine may be complicated by actions of cocaine other than dopamine uptake inhibition. |
1998-09-24 |
2023-08-12 |
rat |
| L Zhang, L W Elmer, K Y Littl. Expression and regulation of the human dopamine transporter in a neuronal cell line. Brain research. Molecular brain research. vol 59. issue 1. 1998-09-23. PMID:9729282. |
human cocaine users exhibit increased striatal [3h]win35428 binding to the dopamine transporter (dat). |
1998-09-23 |
2023-08-12 |
human |
| D Guilloteau, P Emond, J L Baulieu, L Garreau, Y Frangin, L Pourcelot, L Mauclaire, J C Besnard, S Chalo. Exploration of the dopamine transporter: in vitro and in vivo characterization of a high-affinity and high-specificity iodinated tropane derivative (E)-N-(3-iodoprop-2-enyl)-2beta-carbomethoxy-3beta-(4'-m ethylph enyl)nortropane (PE2I). Nuclear medicine and biology. vol 25. issue 4. 1998-09-17. PMID:9639293. |
for the diagnosis and follow-up of neurodegenerative diseases, many cocaine derivatives have been proposed as radioligands to explore the dopamine transporter. |
1998-09-17 |
2023-08-12 |
human |
| P Emond, L Farde, S Chalon, C Belzung, V Mauclaire, J P Chiron, C Halldin, J C Besnard, D Guillotea. Toxicity, mutagenicity, and behavioral effects of beta-CIT, a ligand for dopamine transporter exploration by SPECT. Nuclear medicine and biology. vol 25. issue 4. 1998-09-17. PMID:9639303. |
the cocaine analog beta-cit is one of the most used compounds for spet examination of the dopamine transporter in drug abuse and parkinson's disease. |
1998-09-17 |
2023-08-12 |
mouse |
| B Mets, G Winger, C Cabrera, S Seo, S Jamdar, G Yang, K Zhao, R J Briscoe, R Almonte, J H Woods, D W Landr. A catalytic antibody against cocaine prevents cocaine's reinforcing and toxic effects in rats. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 17. 1998-09-17. PMID:9707620. |
mab 15a10 blocked cocaine specifically and did not affect behavior maintained by milk or by the dopamine reuptake inhibitor bupropion. |
1998-09-17 |
2023-08-12 |
rat |
| K Y Little, D P McLaughlin, L Zhang, P R McFinton, G W Dalack, E H Cook, B J Cassin, S J Watso. Brain dopamine transporter messenger RNA and binding sites in cocaine users: a postmortem study. Archives of general psychiatry. vol 55. issue 9. 1998-09-16. PMID:9736005. |
brain dopamine transporter messenger rna and binding sites in cocaine users: a postmortem study. |
1998-09-16 |
2023-08-12 |
Not clear |
| K Y Little, D P McLaughlin, L Zhang, P R McFinton, G W Dalack, E H Cook, B J Cassin, S J Watso. Brain dopamine transporter messenger RNA and binding sites in cocaine users: a postmortem study. Archives of general psychiatry. vol 55. issue 9. 1998-09-16. PMID:9736005. |
results of recent radioligand binding experiments suggest that chronic cocaine exposure increases dopamine transporter (dat) synthesis throughout the striatum of humans. |
1998-09-16 |
2023-08-12 |
Not clear |
| J V Ferrer, J A Javitc. Cocaine alters the accessibility of endogenous cysteines in putative extracellular and intracellular loops of the human dopamine transporter. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 16. 1998-09-08. PMID:9689064. |
cocaine alters the accessibility of endogenous cysteines in putative extracellular and intracellular loops of the human dopamine transporter. |
1998-09-08 |
2023-08-12 |
human |
| J V Ferrer, J A Javitc. Cocaine alters the accessibility of endogenous cysteines in putative extracellular and intracellular loops of the human dopamine transporter. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 16. 1998-09-08. PMID:9689064. |
cocaine and other psychostimulants act by blocking the dopamine transporter. |
1998-09-08 |
2023-08-12 |
human |
| J V Ferrer, J A Javitc. Cocaine alters the accessibility of endogenous cysteines in putative extracellular and intracellular loops of the human dopamine transporter. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 16. 1998-09-08. PMID:9689064. |
binding of the cocaine analog, [3h]2-beta-carbomethoxy-3-beta-(4-fluorophenyl) tropane (cft) to the dopamine transporter is sensitive to polar sulfhydryl-specific derivatives of methanethiosulfonate (mts). |
1998-09-08 |
2023-08-12 |
human |
| G Le Pen, D Duterte-Boucher, J Costenti. Sensitization to the rewarding effects of the specific dopamine uptake inhibitor GBR12783. The Journal of pharmacology and experimental therapeutics. vol 286. issue 2. 1998-09-02. PMID:9694922. |
the conditioned place preference (cpp) induced by increasing doses (1.25-40 mg/kg) of cocaine or the specific dopamine uptake inhibitor gbr12783 was investigated in rats previously treated with cocaine (10 or 20 mg/kg), gbr12783 (10 mg/kg) or morphine (10 mg/kg) for 15 days. |
1998-09-02 |
2023-08-12 |
rat |
| G Le Pen, D Duterte-Boucher, J Costenti. Sensitization to the rewarding effects of the specific dopamine uptake inhibitor GBR12783. The Journal of pharmacology and experimental therapeutics. vol 286. issue 2. 1998-09-02. PMID:9694922. |
however, prior exposure to morphine sensitized the rats to the rewarding effects of cocaine (2.5 mg/kg) but not to those of gbr12783, suggesting that other mechanisms working in concert with dopamine may facilitate the rewarding effect of cocaine without affecting that of gbr12783. |
1998-09-02 |
2023-08-12 |
rat |