All Relations between cocaine and dopamine

Publication Sentence Publish Date Extraction Date Species
D E Comings, N Gonzalez, S Wu, G Saucier, P Johnson, R Verde, J P MacMurra. Homozygosity at the dopamine DRD3 receptor gene in cocaine dependence. Molecular psychiatry. vol 4. issue 5. 1999-12-10. PMID:10523822. homozygosity at the dopamine drd3 receptor gene in cocaine dependence. 1999-12-10 2023-08-12 human
D E Comings, N Gonzalez, S Wu, G Saucier, P Johnson, R Verde, J P MacMurra. Homozygosity at the dopamine DRD3 receptor gene in cocaine dependence. Molecular psychiatry. vol 4. issue 5. 1999-12-10. PMID:10523822. we examined the hypothesis that the dopamine d3 receptor gene (drd3) is a susceptibility factor for cocaine dependence. 1999-12-10 2023-08-12 human
S A Bennett, J M Arnold, J Chen, J Stenger, D L Paul, D C Robert. Long-term changes in connexin32 gap junction protein and mRNA expression following cocaine self-administration in rats. The European journal of neuroscience. vol 11. issue 9. 1999-11-24. PMID:10510198. considerable evidence indicates a critical role for dopamine in the reinforcing effects of cocaine. 1999-11-24 2023-08-12 rat
S A Bennett, J M Arnold, J Chen, J Stenger, D L Paul, D C Robert. Long-term changes in connexin32 gap junction protein and mRNA expression following cocaine self-administration in rats. The European journal of neuroscience. vol 11. issue 9. 1999-11-24. PMID:10510198. because dopamine has been shown to be a critical modulator of gap junction communication in both eye and brain, we sought to examine whether extended intravenous cocaine self-administration would affect the expression of gap junction channel-forming proteins (connexins). 1999-11-24 2023-08-12 rat
I Sziráki, H Sershen, M Benuck, M Lipovac, A Hashim, T B Cooper, D Allen, A Lajth. The effect of cotinine on nicotine- and cocaine-induced dopamine release in the nucleus accumbens. Neurochemical research. vol 24. issue 11. 1999-11-24. PMID:10555788. in studies on conscious, freely-moving rats, intravenous administration of either nicotine or cocaine induced the release of dopamine in the nucleus accumbens, as assayed by microdialysis. 1999-11-24 2023-08-12 rat
J Helfenbein, J Sandell, C Halldin, S Chalon, P Emond, Y Okubo, Y H Chou, Y Frangin, L Douziech, L Gareau, C G Swahn, J C Besnard, L Farde, D Guillotea. PET examination of three potent cocaine derivatives as specific radioligands for the serotonin transporter. Nuclear medicine and biology. vol 26. issue 5. 1999-11-22. PMID:10473187. rti-364, rti-330, and rti-357 (3-beta-(4'-n-propyl-,4'-iso-propyl-, and 4'-iso-propenyl-phenyl)nortropane-2-beta-carboxylic acid methyl ester) are three recently synthesized cocaine analogues with higher affinity for the serotonin (5-htt) than the dopamine transporter (dat). 1999-11-22 2023-08-12 monkey
S M Husbands, S Izenwasser, T Kopajtic, W D Bowen, B J Vilner, J L Katz, A H Newma. Structure-activity relationships at the monoamine transporters and sigma receptors for a novel series of 9-[3-(cis-3, 5-dimethyl-1-piperazinyl)propyl]carbazole (rimcazole) analogues. Journal of medicinal chemistry. vol 42. issue 21. 1999-11-22. PMID:10543888. although the binding affinities at the dopamine transporter of rimcazole and cocaine are comparable, rimcazole only depressed locomotor activity in mice and antagonized the stimulant effects produced by cocaine. 1999-11-22 2023-08-12 mouse
S M Husbands, S Izenwasser, T Kopajtic, W D Bowen, B J Vilner, J L Katz, A H Newma. Structure-activity relationships at the monoamine transporters and sigma receptors for a novel series of 9-[3-(cis-3, 5-dimethyl-1-piperazinyl)propyl]carbazole (rimcazole) analogues. Journal of medicinal chemistry. vol 42. issue 21. 1999-11-22. PMID:10543888. the neurochemical mechanisms underlying the attenuation of cocaine's effects are not understood, although interaction at a low affinity site/state of the dopamine transporter has been suggested. 1999-11-22 2023-08-12 mouse
S M Husbands, S Izenwasser, T Kopajtic, W D Bowen, B J Vilner, J L Katz, A H Newma. Structure-activity relationships at the monoamine transporters and sigma receptors for a novel series of 9-[3-(cis-3, 5-dimethyl-1-piperazinyl)propyl]carbazole (rimcazole) analogues. Journal of medicinal chemistry. vol 42. issue 21. 1999-11-22. PMID:10543888. these novel rimcazole analogues may provide important tools with which to characterize the relationship between the low affinity site or state of the dopamine transporter, sigma receptors, and their potential roles in modulating cocaine's psychostimulant actions. 1999-11-22 2023-08-12 mouse
C Schmidt-Mutter, C Muller, J Zwiller, S Gobaille, M Maitr. Gamma-hydroxybutyrate and cocaine administration increases mRNA expression of dopamine D1 and D2 receptors in rat brain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 21. issue 5. 1999-11-15. PMID:10516962. gamma-hydroxybutyrate and cocaine administration increases mrna expression of dopamine d1 and d2 receptors in rat brain. 1999-11-15 2023-08-12 rat
S R Letchworth, T Sexton, S R Childers, K E Vrana, R A Vaughan, H M Davies, L J Porrin. Regulation of rat dopamine transporter mRNA and protein by chronic cocaine administration. Journal of neurochemistry. vol 73. issue 5. 1999-11-05. PMID:10537056. regulation of rat dopamine transporter mrna and protein by chronic cocaine administration. 1999-11-05 2023-08-12 rat
S R Letchworth, T Sexton, S R Childers, K E Vrana, R A Vaughan, H M Davies, L J Porrin. Regulation of rat dopamine transporter mRNA and protein by chronic cocaine administration. Journal of neurochemistry. vol 73. issue 5. 1999-11-05. PMID:10537056. this study describes a direct comparison of dopamine transporter (dat) mrna and protein, as well as its binding sites, in tissue from the same animals after chronic cocaine administration. 1999-11-05 2023-08-12 rat
M R Gerasimov, S L Dewe. Gamma-vinyl gamma-aminobutyric acid attenuates the synergistic elevations of nucleus accumbens dopamine produced by a cocaine/heroin (speedball) challenge. European journal of pharmacology. vol 380. issue 1. 1999-11-03. PMID:10513553. these findings indicate that gamma-vinyl gaba can interfere with the synergistic effects produced by the combination of an indirect dopamine releaser (heroin) and a dopamine reuptake blocker (cocaine). 1999-11-03 2023-08-12 Not clear
O Kuche. Peripheral dopamine in hypertension and associated conditions. Journal of human hypertension. vol 13. issue 9. 1999-11-01. PMID:10482970. secondary forms of hypertension (renovascular, renal, polycystic kidneys, mineralocorticoid, pheochromocytoma) associated conditions (renal and heart failure, diabetes, hypovolaemia, mastocytosis) or iatrogenic (cocaine abuse) are mostly reflected by increased dopamine indices, some of them proposed to be counteracting the activation of prohypertensive mechanisms. 1999-11-01 2023-08-12 Not clear
Y Fang, O K Ronneklei. Cocaine upregulates the dopamine transporter in fetal rhesus monkey brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 20. 1999-10-28. PMID:10516315. cocaine upregulates the dopamine transporter in fetal rhesus monkey brain. 1999-10-28 2023-08-12 human
Y Fang, O K Ronneklei. Cocaine upregulates the dopamine transporter in fetal rhesus monkey brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 20. 1999-10-28. PMID:10516315. cocaine is a highly addictive drug that binds to the dopamine transporter (dat), inhibits the reuptake of dopamine, and initiates multiple actions within midbrain dopaminergic systems. 1999-10-28 2023-08-12 human
Y Fang, O K Ronneklei. Cocaine upregulates the dopamine transporter in fetal rhesus monkey brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 20. 1999-10-28. PMID:10516315. in utero cocaine exposure between days 22 and 70 significantly increased dat mrna expression, and the density of [125i]rti-121 binding sites within midbrain dopamine neurons in the 70-d-old fetus. 1999-10-28 2023-08-12 human
Y Fang, O K Ronneklei. Cocaine upregulates the dopamine transporter in fetal rhesus monkey brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 20. 1999-10-28. PMID:10516315. this increased dat expression is accompanied by other presynaptic and postsynaptic neuronal changes, which collectively suggest that midbrain dopamine neurons are hypoactive after prolonged cocaine exposure, a state that may be a contributing factor in the development of attention deficit disorders observed in subjects exposed prenatally to cocaine. 1999-10-28 2023-08-12 human
S Izenwasser, D French, F I Carroll, P M Kunk. Continuous infusion of selective dopamine uptake inhibitors or cocaine produces time-dependent changes in rat locomotor activity. Behavioural brain research. vol 99. issue 2. 1999-10-27. PMID:10512586. continuous infusion of selective dopamine uptake inhibitors or cocaine produces time-dependent changes in rat locomotor activity. 1999-10-27 2023-08-12 rat
S Izenwasser, D French, F I Carroll, P M Kunk. Continuous infusion of selective dopamine uptake inhibitors or cocaine produces time-dependent changes in rat locomotor activity. Behavioural brain research. vol 99. issue 2. 1999-10-27. PMID:10512586. to study the pharmacological mechanisms that underlie this phenomenon, osmotic minipumps containing cocaine or selective uptake inhibitors of dopamine (gbr 12909 or rti-117), serotonin (fluoxetine), or norepinephrine (nisoxetine) were implanted into rats. 1999-10-27 2023-08-12 rat