| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E M Unterwald, M J Kreek, M Cuntapa. The frequency of cocaine administration impacts cocaine-induced receptor alterations. Brain research. vol 900. issue 1. 2001-07-26. PMID:11325352. |
increased dopamine d1 receptor binding was found in the nucleus accumbens and olfactory tubercle following twice daily cocaine injections, but not after single daily injections of the same total daily dose. |
2001-07-26 |
2023-08-12 |
rat |
| C K Hwang, U M D'Souza, A J Eisch, S Yajima, C H Lammers, Y Yang, S H Lee, Y M Kim, E J Nestler, M M Mouradia. Dopamine receptor regulating factor, DRRF: a zinc finger transcription factor. Proceedings of the National Academy of Sciences of the United States of America. vol 98. issue 13. 2001-07-26. PMID:11390978. |
mice treated with drugs that increase extracellular striatal dopamine levels (cocaine), block dopamine receptors (haloperidol), or destroy dopamine terminals (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) show significant alterations in drrf mrna. |
2001-07-26 |
2023-08-12 |
mouse |
| B A Mattingly, A Caudill, M Abe. Differential effects of 7-OH-DPAT on the development of behavioral sensitization to apomorphine and cocaine. Pharmacology, biochemistry, and behavior. vol 68. issue 3. 2001-07-19. PMID:11325394. |
the primary objective of this study was to determine whether concurrent treatments with a low dose of the dopamine d(3)-preferring receptor agonist 7-oh-dpat would attenuate the development of behavioral sensitization to the indirect dopamine receptor agonist, cocaine, or the direct dopamine receptor agonist, apomorphine. |
2001-07-19 |
2023-08-12 |
rat |
| L L Howell, K M Wilco. The dopamine transporter and cocaine medication development: drug self-administration in nonhuman primates. The Journal of pharmacology and experimental therapeutics. vol 298. issue 1. 2001-07-19. PMID:11408518. |
the dopamine transporter and cocaine medication development: drug self-administration in nonhuman primates. |
2001-07-19 |
2023-08-12 |
human |
| L L Howell, K M Wilco. The dopamine transporter and cocaine medication development: drug self-administration in nonhuman primates. The Journal of pharmacology and experimental therapeutics. vol 298. issue 1. 2001-07-19. PMID:11408518. |
given the obvious importance of the dopamine transporter in the addictive properties of cocaine, the development and use of compounds that target the dopamine transporter represents a reasonable approach for the pharmacological treatment of cocaine abuse. |
2001-07-19 |
2023-08-12 |
human |
| L L Howell, K M Wilco. The dopamine transporter and cocaine medication development: drug self-administration in nonhuman primates. The Journal of pharmacology and experimental therapeutics. vol 298. issue 1. 2001-07-19. PMID:11408518. |
a number of preclinical studies with dopamine transporter inhibitors provide evidence that substitute agonists may be used effectively to reduce cocaine use. |
2001-07-19 |
2023-08-12 |
human |
| L L Howell, K M Wilco. The dopamine transporter and cocaine medication development: drug self-administration in nonhuman primates. The Journal of pharmacology and experimental therapeutics. vol 298. issue 1. 2001-07-19. PMID:11408518. |
several cocaine analogs and other dopamine transporter inhibitors, including analogs of gbr 12909 and win 35,065-2, have been shown to reduce cocaine self-administration in nonhuman primates. |
2001-07-19 |
2023-08-12 |
human |
| K Eckermann, A Beasley, P Yang, O Gaytan, A Swann, N Dafn. Methylphenidate sensitization is modulated by valproate. Life sciences. vol 69. issue 1. 2001-07-05. PMID:11411804. |
glutamate, dopamine, and gaba have been implicated in the underlying mechanism of sensitization to stimulants such as amphetamine and cocaine. |
2001-07-05 |
2023-08-12 |
rat |
| J P Pepper, M H Baumann, M Ayestas, R B Rothma. Inhibition of MAO-A fails to alter cocaine-induced increases in extracellular dopamine and norepinephrine in rat nucleus accumbens. Brain research. Molecular brain research. vol 87. issue 2. 2001-06-28. PMID:11245920. |
cocaine administration elicited significant increases in extracellular dopamine and norepinephrine in all groups of rats, and this effect was not altered by clorgyline pretreatment. |
2001-06-28 |
2023-08-12 |
human |
| E F Schmidt, M A Sutton, C A Schad, D A Karanian, E S Brodkin, D W Sel. Extinction training regulates tyrosine hydroxylase during withdrawal from cocaine self-administration. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 7. 2001-06-28. PMID:11264329. |
the ability of extinction training to restore nac th levels is hypothesized to accelerate recovery from dopamine depletion and anhedonia during cocaine withdrawal. |
2001-06-28 |
2023-08-12 |
rat |
| M A Ungless, J L Whistler, R C Malenka, A Bonc. Single cocaine exposure in vivo induces long-term potentiation in dopamine neurons. Nature. vol 411. issue 6837. 2001-06-28. PMID:11385572. |
single cocaine exposure in vivo induces long-term potentiation in dopamine neurons. |
2001-06-28 |
2023-08-12 |
Not clear |
| M A Ungless, J L Whistler, R C Malenka, A Bonc. Single cocaine exposure in vivo induces long-term potentiation in dopamine neurons. Nature. vol 411. issue 6837. 2001-06-28. PMID:11385572. |
here we show that a single in vivo exposure to cocaine induces long-term potentiation of ampa (alpha-amino-3-hydroxy-5-methyl-isoxazole propionic acid)-receptor-mediated currents at excitatory synapses onto dopamine cells in the ventral tegmental area. |
2001-06-28 |
2023-08-12 |
Not clear |
| J S Fowler, N D Volkow, J Logan, D Franceschi, G J Wang, R MacGregor, C Shea, V Garza, N Pappas, P Carter, N Netusil, P Bridge, D Liederman, A Elkashef, J Rotrosen, R Hitzeman. Evidence that L-deprenyl treatment for one week does not inhibit MAO A or the dopamine transporter in the human brain. Life sciences. vol 68. issue 24. 2001-06-28. PMID:11400918. |
each session included one scan with [11c]clorgyline (to assess mao a) and one scan 2 hours later with [11c]cocaine (to assess dopamine transporter availability). |
2001-06-28 |
2023-08-12 |
human |
| C Roubert, P J Cox, M Bruss, M Hamon, H Bönisch, B Giro. Determination of residues in the norepinephrine transporter that are critical for tricyclic antidepressant affinity. The Journal of biological chemistry. vol 276. issue 11. 2001-06-21. PMID:11092898. |
both transport dopamine with higher affinity than norepinephrine and are targets for the psychostimulants cocaine and amphetamine. |
2001-06-21 |
2023-08-12 |
human |
| R R Matsumoto, K A McCracken, B Pouw, J Miller, W D Bowen, W Williams, B R De Cost. N-alkyl substituted analogs of the sigma receptor ligand BD1008 and traditional sigma receptor ligands affect cocaine-induced convulsions and lethality in mice. European journal of pharmacology. vol 411. issue 3. 2001-06-21. PMID:11164383. |
cocaine binds to sigma receptors with comparable affinity to its well-established interaction with dopamine transporters. |
2001-06-21 |
2023-08-12 |
mouse |
| M R Gerasimov, W K Schiffer, E L Gardner, D A Marsteller, I C Lennon, S J Taylor, J D Brodie, C R Ashby, S L Dewe. GABAergic blockade of cocaine-associated cue-induced increases in nucleus accumbens dopamine. European journal of pharmacology. vol 414. issue 2-3. 2001-06-21. PMID:11239920. |
to better understand the neurochemical mechanisms potentially mediating these cues, we measured nucleus accumbens dopamine levels in animals exposed to environmental cues previously paired with cocaine administration. |
2001-06-21 |
2023-08-12 |
Not clear |
| E G Eising, T H Müller, L Freudenberg, S P Müller, K Dutschka, W Sonnenschein, H Przuntek, A Bockisc. SPECT imaging with [123I]-beta-CIT in Parkinsonism: comparison of SPECT images obtained by a single-headed and a three-headed gamma camera. Nuclear medicine communications. vol 22. issue 2. 2001-06-21. PMID:11258400. |
single photon emission computed tomography (spect) imaging of dopamine transporters by using the cocaine derivative [123i]-(1r)-2-beta-carbomethoxy-3-beta-(4-iodophenyl)-tropane ([123i]-beta-cit) has been shown to be useful in patients with parkinsonism. |
2001-06-21 |
2023-08-12 |
Not clear |
| K Lutfy, T Do, N T Maidmen. Orphanin FQ/nociceptin attenuates motor stimulation and changes in nucleus accumbens extracellular dopamine induced by cocaine in rats. Psychopharmacology. vol 154. issue 1. 2001-06-21. PMID:11291998. |
orphanin fq/nociceptin attenuates motor stimulation and changes in nucleus accumbens extracellular dopamine induced by cocaine in rats. |
2001-06-21 |
2023-08-12 |
rat |
| E Carboni, A Silvagni, M T Rolando, G Di Chiar. Stimulation of in vivo dopamine transmission in the bed nucleus of stria terminalis by reinforcing drugs. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 20. 2001-06-07. PMID:11027253. |
we report that morphine, nicotine, cocaine, ethanol, and the selective dopamine uptake inhibitor gbr 12909 increase effectively and dose dependently extracellular dopamine in the bed nucleus of stria terminalis. |
2001-06-07 |
2023-08-12 |
Not clear |
| R S Sinnott, M A Nade. Modulation of cocaine's discriminative stimulus effects by dopamine D(1) agonists in rhesus monkeys. Pharmacology, biochemistry, and behavior. vol 68. issue 2. 2001-06-07. PMID:11267635. |
modulation of cocaine's discriminative stimulus effects by dopamine d(1) agonists in rhesus monkeys. |
2001-06-07 |
2023-08-12 |
human |