| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Bianchi, E De Micheli, A Bricolo, C Ballini, M Fattori, C Venturi, F Pedata, K F Tipton, L Della Cort. Extracellular levels of amino acids and choline in human high grade gliomas: an intraoperative microdialysis study. Neurochemical research. vol 29. issue 1. 2004-08-17. PMID:14992293. |
there was no difference between grade iii and grade iv tumors in the concentrations of phenylalanine, isoleucine, tyrosine, valine, and lysine, whereas the concentrations of choline, aspartate, taurine, gaba, leucine, and glutamate were significantly different in the two tumor-grade subgroups. |
2004-08-17 |
2023-08-12 |
human |
| Fei Du, Wen-Jang Chu, Baolian Yang, Jan A Den Hollander, Thian C N. In vivo GABA detection with improved selectivity and sensitivity by localized double quantum filter technique at 4.1T. Magnetic resonance imaging. vol 22. issue 1. 2004-06-10. PMID:14972399. |
our editing efficiency of 40-50% was achievable on a gaba phantom (50 mm gaba and 61 mm choline). |
2004-06-10 |
2023-08-12 |
human |
| Alfonso Di Costanzo, F Trojsi, M Tosetti, G M Giannatempo, F Nemore, M Piccirillo, S Bonavita, G Tedeschi, T Scarabin. High-field proton MRS of human brain. European journal of radiology. vol 48. issue 2. 2004-03-25. PMID:14680905. |
in addition to improved measurement precision of n-acetylaspartate, choline, creatine and myo-inositol, high-field systems allow the high-resolution measurement of other metabolites, such as glutamate, glutamine, gamma-aminobutyric acid, scyllo-inositol, aspartate, taurine, n-acetylaspartylglutamate, glucose and branched amino acids, thus extending the range of metabolic information. |
2004-03-25 |
2023-08-12 |
human |
| C C Cloak, L Chang, T Ernst, M C Barr, S Huitron-Resendiz, M Sanchez-Alavez, T R Phillips, S Henrikse. Methamphetamine and AIDS: 1HMRS studies in a feline model of human disease. Journal of neuroimmunology. vol 147. issue 1-2. 2004-03-15. PMID:14741420. |
in the frontal white matter, fiv-infected cats showed decreases in creatine and choline, while ma-treated cats had elevated gamma-aminobutyric acid (gaba). |
2004-03-15 |
2023-08-12 |
human |
| Christophe Bossuet, Françoise Vaufrey, Françoise Condé, Fabrice Chrétien, Jacques Pichon, Philippe Hantraye, Roger Le Grand, Dominique Dormont, Gabriel Gra. Up-regulation of glutamate concentration in the putamen and in the prefrontal cortex of asymptomatic SIVmac251-infected macaques without major brain involvement. Journal of neurochemistry. vol 88. issue 4. 2004-03-15. PMID:14756814. |
absolute concentrations of acetate, alanine, aspartate, choline, creatine, gaba, glutamate, glutamine, lactate, myo-inositol, n-acetylaspartate, taurine and valine were determined by ex vivo proton magnetic resonance spectroscopy. |
2004-03-15 |
2023-08-12 |
Not clear |
| J L Griffin, C K Cemal, M A Poo. Defining a metabolic phenotype in the brain of a transgenic mouse model of spinocerebellar ataxia 3. Physiological genomics. vol 16. issue 3. 2004-03-11. PMID:14679302. |
as well as an increase in glutamine both brain regions demonstrated decreases in gaba, choline, phosphocholine and lactate (representing the summation of lactate in vivo, and postmortem glycolysis of glucose and glycogen). |
2004-03-11 |
2023-08-12 |
mouse |
| T Hammen, H Stefan, K E Eberhardt, B H W-Huk, B F Tomand. Clinical applications of 1H-MR spectroscopy in the evaluation of epilepsies--what do pathological spectra stand for with regard to current results and what answers do they give to common clinical questions concerning the treatment of epilepsies? Acta neurologica Scandinavica. vol 108. issue 4. 2003-12-05. PMID:12956855. |
nuclear magnetic resonance spectroscopy (1h-mrs) is a non-invasive method in detecting abnormal spectra of various brain metabolites containing n-acetylaspartate (naa), choline (cho), creatine (cr), gamma-aminobutyric acid (gaba) and glutamate. |
2003-12-05 |
2023-08-12 |
Not clear |
| J M Durán, M J Peral, M L Calonge, A A Ilundái. Functional characterization of intestinal L-carnitine transport. The Journal of membrane biology. vol 185. issue 1. 2003-08-27. PMID:11891565. |
l-carnitine uptake into either enterocytes or bbmv was inhibited by excess amount of cold l-carnitine > d-carnitine = acetyl-l-carnitine = gamma-butyrobetaine > palmitoyl-l-carnitine > betaine > tea, whereas alanine, histidine, gaba or choline were without significant effect. |
2003-08-27 |
2023-08-12 |
chicken |
| M J Peral, M García-Delgado, M L Calonge, J M Durán, M C De La Horra, T Wallimann, O Speer, A Ilundái. Human, rat and chicken small intestinal Na+ - Cl- -creatine transporter: functional, molecular characterization and localization. The Journal of physiology. vol 545. issue 1. 2003-05-07. PMID:12433955. |
more distant structural analogues of creatine, such as gaba, choline, glycine, beta-alanine, taurine and betaine, had no effect on intestinal creatine uptake, indicating a high substrate specificity of the creatine transporter. |
2003-05-07 |
2023-08-12 |
human |
| Nanna MacAulay, Thomas Zeuthen, Ulrik Gethe. Conformational basis for the Li(+)-induced leak current in the rat gamma-aminobutyric acid (GABA) transporter-1. The Journal of physiology. vol 544. issue 2. 2003-04-15. PMID:12381817. |
in addition, it was found that the gaba transport current was sustained at correspondingly low na(+) concentrations if li(+) was present instead of choline. |
2003-04-15 |
2023-08-12 |
rat |
| D Seto, W-H Zheng, A McNicoll, B Collier, R Quirion, S Ka. Insulin-like growth factor-I inhibits endogenous acetylcholine release from the rat hippocampal formation: possible involvement of GABA in mediating the effects. Neuroscience. vol 115. issue 2. 2003-01-23. PMID:12421625. |
in the present study, we have characterized the possible involvement of gaba in igf-i-mediated inhibition of ach release and measured the effects of this growth factor on choline acetyltransferase (chat) activity and high-affinity choline uptake in the hippocampus of the adult rat brain. |
2003-01-23 |
2023-08-12 |
rat |
| Gregory J Moore, Matthew P Gallowa. Magnetic resonance spectroscopy: neurochemistry and treatment effects in affective disorders. Psychopharmacology bulletin. vol 36. issue 2. 2002-11-19. PMID:12397837. |
for example, several independent groups have reported alterations in levels of choline, myoinositol, n-acetylaspartate, and gamma-aminobutyric acid in the central nervous systems of patients with major depression, bipolar disorder, panic disorder, or obsessive-compulsive disorder. |
2002-11-19 |
2023-08-12 |
Not clear |
| Sylvie Poluch, Norbert Köni. AMPA receptor activation induces GABA release from neurons migrating tangentially in the intermediate zone of embryonic rat neocortex. The European journal of neuroscience. vol 16. issue 2. 2002-11-06. PMID:12169116. |
in contrast, it was abolished after sodium substitution by choline, or after coapplication of nipecotic acid, a gaba transporter inhibitor. |
2002-11-06 |
2023-08-12 |
rat |
| S A Menzikov, O V Menzikov. Effect of activators and blockers of ligand-regulated ion channels on the activity of the Cl-stimulated Mg2+-ATPase of the plasma membrane fraction from bream (Abramis brama L.) brain. Biochemistry. Biokhimiia. vol 67. issue 2. 2002-08-13. PMID:11952420. |
effects of gaba, glycine, acetylcholine, and glutamate (agonists of the gabaa/benzodiazepine, glycine, choline, and glutamate receptors, respectively) at concentrations in the range 10(-8)-10(-4) m on the activity of "basal" mg(2+)-atpase of the plasma membrane fraction from bream brain and on its activation by cl(-) were investigated. |
2002-08-13 |
2023-08-12 |
Not clear |
| J-Z Guo, V A Chiappinell. A novel choline-sensitive nicotinic receptor subtype that mediates enhanced GABA release in the chick ventral lateral geniculate nucleus. Neuroscience. vol 110. issue 3. 2002-06-12. PMID:11906789. |
during long-term (5 min) exposure to choline the gaba enhancement was maintained until choline was washed out. |
2002-06-12 |
2023-08-12 |
chicken |
| K Z Shen, S W Johnso. Potentiation of GABA(A) receptor agonists by GABA uptake inhibitors in the rat ventral midbrain. European journal of pharmacology. vol 428. issue 1. 2002-04-02. PMID:11779025. |
equimolar replacement of na+ with choline increased gaba-evoked currents, suggesting that a low na+ concentration has an inhibitory effect on gaba transport. |
2002-04-02 |
2023-08-12 |
rat |
| I D Grachev, A V Apkaria. Multi-chemical networking profile of the living human brain: potential relevance to molecular studies of cognition and behavior in normal and diseased brain. Journal of neural transmission (Vienna, Austria : 1996). vol 109. issue 1. 2002-03-14. PMID:11793159. |
in vivo proton magnetic resonance spectroscopy was used to determine relative concentrations of multiple chemicals (n-acetyl aspartate, choline, glutamate, glutamine, gaba, inositol, glucose, and lactate in relation to creatine/phosphocreatine complex) in 6 brain regions: thalamus, and cingulate, insula, sensorimotor, orbital frontal, and dorsolateral prefrontal cortices. |
2002-03-14 |
2023-08-12 |
human |
| Marta García-Delgado, María J Peral, Mercedes Cano, María L Calonge, Anunciación A Ilundái. Creatine transport in brush-border membrane vesicles isolated from rat kidney cortex. Journal of the American Society of Nephrology : JASN. vol 12. issue 9. 2001-12-04. PMID:11518774. |
creatine uptake was inhibited by a 100-fold excess of various compounds with the following potency order: cold creatine = guanidinopropionic acid > nipecotic acid > gamma-aminobutyric acid (gaba) = beta-alanine = betaine, whereas carnitine, glycine, taurine, and choline were without effect. |
2001-12-04 |
2023-08-12 |
rat |
| G Fontana, G Taccola, J Galante, S Salis, M Raiter. AMPA-evoked acetylcholine release from cultured spinal cord motoneurons and its inhibition by GABA and glycine. Neuroscience. vol 106. issue 1. 2001-12-04. PMID:11564428. |
the release of [(3)h]acetylcholine evoked by alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (ampa) and its inhibition mediated by gaba(a) and glycine receptors were studied in superfused cultured rat embryo spinal cord motoneurons prelabeled with [(3)h]choline. |
2001-12-04 |
2023-08-12 |
rat |
| A V Pozdniakov, L A Tiutin, G N Bisaga, M M Odina. [Proton magnetic-resonance spectroscopy in remitting and secondary-progressive multiple sclerosis]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 101. issue 4. 2001-10-04. PMID:11490432. |
proton magnetic-resonance spectroscopy (pmrs) was used to measure the levels of inositol/myoinositol (ins), choline, creatine/phosphocreatine (cr), glutamine/glutamate (glx/glx1), n-acetylaspartate (naa), gamma-aminobutyric acid (gaba) and lipids were measured in the foci of demyelinization in the brains of 59 patients with multiple sclerosis (ms). |
2001-10-04 |
2023-08-12 |
Not clear |