| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Miri Gitik, Erica D Holliday, Ming Leung, Qiaoping Yuan, Sheree F Logue, Roope Tikkanen, David Goldman, Thomas J Goul. Choline ameliorates adult learning deficits and reverses epigenetic modification of chromatin remodeling factors related to adolescent nicotine exposure. Neurobiology of learning and memory. vol 155. 2019-09-23. PMID:30099202. |
our findings support a role for epigenetic modification of hippocampal chromatin remodeling genes in long-term learning deficits induced by adolescent nicotine and their amelioration by dietary choline supplementation. |
2019-09-23 |
2023-08-13 |
mouse |
| Jong Whi Kim, Kyu Ri Hahn, Dae Young Yoo, Hyo Young Jung, In Koo Hwang, Je Kyung Seong, Yeo Sung Yoo. Methionine-Choline Deprivation Impairs Adult Hippocampal Neurogenesis in C57BL/6 Mice. Journal of medicinal food. vol 22. issue 4. 2019-07-16. PMID:30990755. |
in this study, we investigated the effects of methionine and choline deficiency on adult hippocampal neurogenesis and neural stem cell (nsc) lineage in the adult stage. |
2019-07-16 |
2023-08-13 |
mouse |
| Jong Whi Kim, Kyu Ri Hahn, Dae Young Yoo, Hyo Young Jung, In Koo Hwang, Je Kyung Seong, Yeo Sung Yoo. Methionine-Choline Deprivation Impairs Adult Hippocampal Neurogenesis in C57BL/6 Mice. Journal of medicinal food. vol 22. issue 4. 2019-07-16. PMID:30990755. |
these results suggest that suitable levels of methionine and choline are essential for the maintenance of hippocampal neurogenesis in mice and affect nsc proliferation and differentiation through phosphorylation of creb. |
2019-07-16 |
2023-08-13 |
mouse |
| Natalie L Voets, Carl J Hodgetts, Arjune Sen, Jane E Adcock, Uzay Emi. Hippocampal MRS and subfield volumetry at 7T detects dysfunction not specific to seizure focus. Scientific reports. vol 7. issue 1. 2019-07-08. PMID:29170537. |
hippocampal metabolite spectra were acquired to determine absolute concentrations of glutamate, glutamine, myo-inositol, naa, creatine and choline. |
2019-07-08 |
2023-08-13 |
human |
| Yuji Sahara, Daisuke Matsuzawa, Daisuke Ishii, Takahiro Fuchida, Takashi Goto, Chihiro Sutoh, Eiji Shimiz. Paternal methyl donor deficient diets during development affect male offspring behavior and memory-related gene expression in mice. Developmental psychobiology. vol 61. issue 1. 2019-05-29. PMID:30460679. |
in our previous study, a methyl-donors (folate, methionine, and choline)-deficient (fmcd) diet during the juvenile period could be shown to affect anxiety-like behavior and fear memory, accompanied by alteration in some gene expression and their methylations in the hippocampus. |
2019-05-29 |
2023-08-13 |
mouse |
| N N Shusharina, M V Patrushev, E V Silina, V A Stupin, P F Litvitsky, A S Orlov. [Expression of genes for neurotransmitter transporters in astrocytes in different brain regions in experiment]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 118. issue 6. 2019-05-17. PMID:30040802. |
to investigate the expression of transporters of different neurotransmitters (glutamate, aspartate, lactate, choline) in the culture of astrocytes isolated from different regions of the brain (cortex, hippocampus and brainstem) in 3- and 11-day rats. |
2019-05-17 |
2023-08-13 |
rat |
| Chelsea A Nickerson, Alexandra L Brown, Waylin Yu, Yoona Chun, Melissa J Glen. Prenatal choline supplementation attenuates MK-801-induced deficits in memory, motor function, and hippocampal plasticity in adult male rats. Neuroscience. vol 361. 2018-06-14. PMID:28790020. |
prenatal choline supplementation attenuates mk-801-induced deficits in memory, motor function, and hippocampal plasticity in adult male rats. |
2018-06-14 |
2023-08-13 |
rat |
| Chelsea A Nickerson, Alexandra L Brown, Waylin Yu, Yoona Chun, Melissa J Glen. Prenatal choline supplementation attenuates MK-801-induced deficits in memory, motor function, and hippocampal plasticity in adult male rats. Neuroscience. vol 361. 2018-06-14. PMID:28790020. |
using doublecortin and ki67 to mark neurogenesis and cell division, respectively, in the hippocampus, we found that prenatal choline supplementation, in the face of mk-801 toxicity, protected against reduced hippocampal plasticity. |
2018-06-14 |
2023-08-13 |
rat |
| Bruce C Kennedy, Phu V Tran, Maulika Kohli, Jamie J Maertens, Jonathan C Gewirtz, Michael K Georgief. Beneficial effects of postnatal choline supplementation on long-Term neurocognitive deficit resulting from fetal-Neonatal iron deficiency. Behavioural brain research. vol 336. 2018-06-01. PMID:28811181. |
in rodents, prenatal choline supplementation can diminish long-term hippocampal gene dysregulation and neurocognitive deficits caused by iron deficiency. |
2018-06-01 |
2023-08-13 |
rat |
| Iñigo Murga, Virginia Guillen, José-Vicente Lafuent. Cerebral magnetic resonance changes associated with fibromyalgia syndrome. Medicina clinica. vol 148. issue 11. 2018-04-04. PMID:28450073. |
modifications in gray and white matter volume, as well as in levels of n-acetylaspartate, choline or glutamate, among other metabolites, have been observed in the hippocampus, insula, prefrontal and cingular cortex. |
2018-04-04 |
2023-08-13 |
Not clear |
| Michiko Oya, Hiromi Suzuki, Andrea Roxanne J Anas, Koichi Oishi, Kenji Ono, Shun Yamaguchi, Megumi Eguchi, Makoto Sawad. LC-MS/MS imaging with thermal film-based laser microdissection. Analytical and bioanalytical chemistry. vol 410. issue 2. 2018-03-09. PMID:29184999. |
with this imaging technique, we successfully obtained the distributions of pilocarpine, glutamate, γ-aminobutyric acid, acetylcholine, and choline in a cross-section of mouse hippocampus. |
2018-03-09 |
2023-08-13 |
mouse |
| E Albiñana, J G Luengo, A M Baraibar, M D Muñoz, L Gandía, J M Solís, J M Hernández-Guij. Choline induces opposite changes in pyramidal neuron excitability and synaptic transmission through a nicotinic receptor-independent process in hippocampal slices. Pflugers Archiv : European journal of physiology. vol 469. issue 5-6. 2018-03-05. PMID:28176016. |
choline induces opposite changes in pyramidal neuron excitability and synaptic transmission through a nicotinic receptor-independent process in hippocampal slices. |
2018-03-05 |
2023-08-13 |
mouse |
| E Albiñana, J G Luengo, A M Baraibar, M D Muñoz, L Gandía, J M Solís, J M Hernández-Guij. Choline induces opposite changes in pyramidal neuron excitability and synaptic transmission through a nicotinic receptor-independent process in hippocampal slices. Pflugers Archiv : European journal of physiology. vol 469. issue 5-6. 2018-03-05. PMID:28176016. |
in this study, we determined how choline affects action potentials and excitatory synaptic transmission using extracellular and intracellular recording techniques in ca1 area of hippocampal slices obtained from both mice and rats. |
2018-03-05 |
2023-08-13 |
mouse |
| Sridevi Balaraman, Nirelia M Idrus, Rajesh C Miranda, Jennifer D Thoma. Postnatal choline supplementation selectively attenuates hippocampal microRNA alterations associated with developmental alcohol exposure. Alcohol (Fayetteville, N.Y.). vol 60. 2018-02-05. PMID:28433422. |
postnatal choline supplementation selectively attenuates hippocampal microrna alterations associated with developmental alcohol exposure. |
2018-02-05 |
2023-08-13 |
human |
| Sridevi Balaraman, Nirelia M Idrus, Rajesh C Miranda, Jennifer D Thoma. Postnatal choline supplementation selectively attenuates hippocampal microRNA alterations associated with developmental alcohol exposure. Alcohol (Fayetteville, N.Y.). vol 60. 2018-02-05. PMID:28433422. |
we have shown that supplementation with the nutrient choline reduces the severity of developmental alcohol-associated deficits in hippocampal-dependent behaviors and normalizes some aspects of hippocampal cholinergic development and dna methylation patterns. |
2018-02-05 |
2023-08-13 |
human |
| Brian E Powers, Christy M Kelley, Ramon Velazquez, Jessica A Ash, Myla S Strawderman, Melissa J Alldred, Stephen D Ginsberg, Elliott J Mufson, Barbara J Strup. Maternal choline supplementation in a mouse model of Down syndrome: Effects on attention and nucleus basalis/substantia innominata neuron morphology in adult offspring. Neuroscience. vol 340. 2017-11-07. PMID:27840230. |
our prior studies demonstrated that maternal choline supplementation (mcs) improves attention and spatial cognition in ts65dn offspring, normalizes hippocampal neurogenesis, and lessens bfcn degeneration in the medial septal nucleus (msn). |
2017-11-07 |
2023-08-13 |
mouse |
| Cui-Hong Zhu, Ting Wu, Yu Jin, Bi-Xia Huang, Rui-Fen Zhou, Yi-Qin Wang, Xiao-Lin Luo, Hui-Lian Zh. Prenatal choline supplementation attenuates spatial learning deficits of offspring rats exposed to low-protein diet during fetal period. The Journal of nutritional biochemistry. vol 32. 2017-10-09. PMID:27142732. |
prenatal choline supplementation could attenuate the spatial learning deficits caused by prenatal protein malnutrition by increasing brain choline, betaine and phospholipids and by influencing the hippocampus structure. |
2017-10-09 |
2023-08-13 |
rat |
| Tiffany J Mellott, Olivia M Huleatt, Bethany N Shade, Sarah M Pender, Yi B Liu, Barbara E Slack, Jan K Blusztaj. Perinatal Choline Supplementation Reduces Amyloidosis and Increases Choline Acetyltransferase Expression in the Hippocampus of the APPswePS1dE9 Alzheimer's Disease Model Mice. PloS one. vol 12. issue 1. 2017-08-14. PMID:28103298. |
perinatal choline supplementation reduces amyloidosis and increases choline acetyltransferase expression in the hippocampus of the appsweps1de9 alzheimer's disease model mice. |
2017-08-14 |
2023-08-13 |
mouse |
| Jaivijay Ramu, Tetyana Konak, Serguei Liachenk. Magnetic resonance spectroscopic analysis of neurometabolite changes in the developing rat brain at 7T. Brain research. vol 1651. 2017-07-28. PMID:27663970. |
some differences between our data and the published literature were observed in the concentrations and dynamics of phosphocreatine, myo-inositol, and gaba in the hippocampus and creatine, gaba, glutamine, choline and n-acetyl-aspartate in the cortex. |
2017-07-28 |
2023-08-13 |
rat |
| Xu Rui, Li Wenfang, Cheng Jing, Chen Meng, Ding Chengcheng, Xu Jiqu, Rong Shuan. Neuroprotective effects of phytosterol esters against high cholesterol-induced cognitive deficits in aged rat. Food & function. vol 8. issue 3. 2017-07-07. PMID:28256666. |
furthermore, pse improved cholinergic activities by restoring the acetylcholine (ach) content and decreasing acetylcholinesterase (ache) activity in the cerebral cortex, as well as by elevating choline acetyl transferase (chat) activity in the hippocampus and the cerebral cortex. |
2017-07-07 |
2023-08-13 |
rat |