| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Kozuk. Changes in brain energy metabolism, neurotransmitters, and choline during and after incomplete cerebral ischemia in spontaneously hypertensive rats. Neurochemical research. vol 20. issue 1. 1995-06-07. PMID:7739755. |
we measured concentrations of atp, phosphocreatine (pcr), lactate (lac), glucose (glu), acetylcholine (ach), choline (ch), and gamma-aminobutyric acid (gaba) in both the cerebral cortex and the subcortical regions after 1 h ischemia, 2 h ischemia, and 2 h reflow following 2 h ischemia, and then examined changes in concentrations of these substances during and after incomplete cerebral ischemia. |
1995-06-07 |
2023-08-12 |
rat |
| F Casamenti, C Scali, L Giovannelli, M S Faussone-Pellegrini, G Pepe. Effect of nerve growth factor and GM1 ganglioside on the recovery of cholinergic neurons after a lesion of the nucleus basalis in aging rats. Journal of neural transmission. Parkinson's disease and dementia section. vol 7. issue 3. 1995-05-17. PMID:7710670. |
intracerebroventricular administration of nerve growth factor (10 micrograms twice a week) to aging lesioned rats for 3 weeks after surgery resulted in a complete recovery in the number of choline acetyltransferase-immunoreactive neurons in the nucleus basalis of both sides, and choline acetyltransferase activity in the contralateral cortex, with little effect on the ipsilateral cortex. |
1995-05-17 |
2023-08-12 |
rat |
| S L Gage, S R Keim, J R Simon, W C Lo. Cholinergic innervation of the retrosplenial cortex via the fornix pathway as determined by high affinity choline uptake, choline acetyltransferase activity, and muscarinic receptor binding in the rat. Neurochemical research. vol 19. issue 11. 1995-04-26. PMID:7534875. |
cholinergic innervation of the retrosplenial cortex via the fornix pathway as determined by high affinity choline uptake, choline acetyltransferase activity, and muscarinic receptor binding in the rat. |
1995-04-26 |
2023-08-12 |
rat |
| L Aguis, M Hadjiconstantinou, Z X Qu, N H Neff, D K Pearl, A J Yate. GM1 ganglioside and darkly staining neurons in brains of rats subjected to neonatal hypoxia-ischemia. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 12. issue 7. 1995-04-25. PMID:7900544. |
the animals that survived for three weeks after the hypoxic-ischemic episode had clusters of darkly stained (hematoxylin-eosin) neurons in the cortex and reduced uptake of dopamine (frontal cortex) and choline (frontal cortex, hippocampus and striatum) in preparations of synaptosomes. |
1995-04-25 |
2023-08-12 |
rat |
| J Kuhmonen, J Sivenius, P J Riekkinen, R A Kauppine. Decrease in brain choline-containing compounds following a short period of global ischemia in gerbils as detected by 1H NMR spectroscopy in vivo. NMR in biomedicine. vol 7. issue 5. 1995-03-14. PMID:7848813. |
high-resolution 1h nmr of acid-extracted brain cortices showed a decrease in total cho (glycerophosphocholine, phosphocholine and choline) by 31%, but no changes in naa, total creatine, taurine and myo-inositol, in the brain cortex seven days postischaemia relative to control animals. |
1995-03-14 |
2023-08-12 |
Not clear |
| Y Nakamura, H Kubo, K Kataok. Uptake of transmitter amino acids by glial plasmalemmal vesicles from different regions of rat central nervous system. Neurochemical research. vol 19. issue 9. 1995-02-14. PMID:7824067. |
in the present study, we prepared gpv from different regions of rat cns, namely olfactory bulb (ob), cerebral cortex (cx), caudatoputamen (cp), hippocampus (hp), cerebellum (ce) and spinal cord (sc), and analyzed their activities of na(+)-dependent uptake of following neurotransmitters and a related compound; glutamate, gamma-aminobutyrate (gaba), glycine, dopamine and choline. |
1995-02-14 |
2023-08-12 |
rat |
| b' N Naumovi\\xc4\\x87, D Filipovi\\xc4\\x87, V Iveti\\xc4\\x87, V Nikoli\\xc4\\x8. [Habituation and effects of protein synthesis blockers on neuronal activity in the cerebral sensorimotor cortex in rabbits]. Medicinski pregled. vol 46. issue 7-8. 1994-11-28. PMID:7968820.' |
microiontophoretic application of actinomycin d and cyclohexamide compromised the occurrence of habituation in high number of registered neurons, while the application of a neurotransmitter, acetyl choline, promoted habituation in the sensorimotor brain cortex neurons of immature experimental animals. |
1994-11-28 |
2023-08-12 |
Not clear |
| P A Lapchak, D M Araujo, G Pasinetti, F Heft. Differential alterations of cortical cholinergic and neurotensin markers following ibotenic acid lesions of the nucleus basalis magnocellularis. Brain research. vol 613. issue 2. 1994-06-21. PMID:8186970. |
at various time points following ibotenic acid lesions of the nbm, choline acetyltransferase (chat) activity or the capacity of cortical cholinergic neurons to synthesize [3h]acetylcholine (ach) from the precursor molecule [3h]choline were measured in the frontoparietal cortex. |
1994-06-21 |
2023-08-12 |
Not clear |
| E Bronzetti, L Felici, F Ament. Effect of ipsilateral lesioning of the nucleus basalis magnocellularis and of L-alpha-glyceryl phosphorylcholine treatment on choline acetyltransferase and acetylcholinesterase in the rat fronto-parietal cortex. Neuroscience letters. vol 164. issue 1-2. 1994-05-09. PMID:8152614. |
the present study assesses the effect of unilateral lesions of the nucleus basalis magnocellularis (nbm) and of treatment with l-alpha-glyceryl phosphorylcholine (gfc, choline alfoscerate) on the acetylcholine-synthesizing (choline acetyltransferase (chat)), and acetylcholine-degradating (acetylcholinesterase (ache)) enzymes in the rat fronto-parietal cortex ipsilateral to the lesion. |
1994-05-09 |
2023-08-12 |
rat |
| L Garofalo, A C Cuell. Nerve growth factor and the monosialoganglioside GM1: analogous and different in vivo effects on biochemical, morphological, and behavioral parameters of adult cortically lesioned rats. Experimental neurology. vol 125. issue 2. 1994-03-23. PMID:8313938. |
gm1 and ngf equally prevented these deficits in the nbm and, furthermore, enhanced chat activity and choline uptake in the remaining cortex ipsilateral to the lesion site. |
1994-03-23 |
2023-08-12 |
rat |
| W Reimann, G D Bartoszyk, U Köllhofer, F Schneider, U Schoenher. Effects of ageing and long-term operant conditioning on behavior and presynaptic cholinergic and dopaminergic neuronal mechanisms in rats. Archives internationales de pharmacodynamie et de therapie. vol 325. 1994-03-22. PMID:8110029. |
striatal and cerebral cortex slices were preincubated with [3h]dopamine and [3h]choline, respectively, superfused and stimulated electrically. |
1994-03-22 |
2023-08-12 |
rat |
| Y Ikarashi, A Takahashi, H Ishimaru, T Arai, Y Maruyam. Effects of choline-free plasma induced by choline oxidase on regional levels of choline and acetylcholine in rat brain. Brain research bulletin. vol 32. issue 6. 1993-12-14. PMID:8221157. |
choline-free plasma (cfp) was induced in rats by intravenous (iv) injection of 56.0 x 10(2) units kg-1 of choline oxidase (cho) which completely metabolized the free ch circulating in the plasma for at least 15.0 h and caused subsequent significant decrease in the concentration of free ch in the three brain regions examined, the striatum, hippocampus, and cortex. |
1993-12-14 |
2023-08-12 |
rat |
| L Nilsson-Håkansson, I Civalero, X Zhang, C Carlsson-Skwirut, V R Sara, A Nordber. Effects of IGF-1, truncated IGF-1 and the tripeptide Gly-Pro-Glu on acetylcholine release from parietal cortex of rat brain. Neuroreport. vol 4. issue 9. 1993-11-29. PMID:8219036. |
in the concentration range of 10(-10)-10(-5) m, gpe did not interact with the choline uptake sites ([3h]hemicholinium binding) or the muscarinic ([3h]qnb) receptor binding sites in rat cortex. |
1993-11-29 |
2023-08-12 |
rat |
| Z Pittel, E Heldman, R Rubinstein, S Cohe. Inhibition of choline efflux results in enhanced acetylcholine synthesis and release in the guinea-pig corticocerebral synaptosomes. Neurochemistry international. vol 20. issue 2. 1993-07-12. PMID:1284802. |
synthesis and release of [3h]acetylcholine ([3h]ach) were measured in synaptosomes from the guinea pig cerebral cortex after preloading with [3h]choline ([3h]ch). |
1993-07-12 |
2023-08-11 |
Not clear |
| C G Benishi. Actions of ginsenoside Rb1 on choline uptake in central cholinergic nerve endings. Neurochemistry international. vol 21. issue 1. 1993-06-24. PMID:1338897. |
however, chronic (3 day) administration of rb1 did increase the number of choline uptake sites in the hippocampus, and to a lesser extent in the cortex. |
1993-06-24 |
2023-08-11 |
rat |
| D J Meyerhoff, S MacKay, L Bachman, N Poole, W P Dillon, M W Weiner, G Fei. Reduced brain N-acetylaspartate suggests neuronal loss in cognitively impaired human immunodeficiency virus-seropositive individuals: in vivo 1H magnetic resonance spectroscopic imaging. Neurology. vol 43. issue 3 Pt 1. 1993-04-13. PMID:8450992. |
1h spectra from nine 2.5-ml volumes in the centrum semiovale and the mesial cortex showed significantly reduced n-acetylaspartate (naa) relative to choline and creatine in the cognitively impaired hiv-infected subjects. |
1993-04-13 |
2023-08-12 |
human |
| Z Deri, P Bors, V Adam-Viz. Effect of alpha-latrotoxin on acetylcholine release and intracellular Ca2+ concentration in synaptosomes: Na(+)-dependent and Na(+)-independent components. Journal of neurochemistry. vol 60. issue 3. 1993-03-24. PMID:8436959. |
plasma membrane potential, and high-affinity choline uptake of synaptosomes isolated from guinea pig cortex. |
1993-03-24 |
2023-08-12 |
Not clear |
| N M Giusto, M E Roque, M G Ilincheta de Boscher. Effects of aging on the content, composition and synthesis of sphingomyelin in the central nervous system. Lipids. vol 27. issue 11. 1993-03-01. PMID:1491598. |
in vitro synthesis of sph from [3h]choline and [3h]palmitic acid in cerebral cortex and cerebellum showed no significant differences between adult rats and those 21.5 months of age. |
1993-03-01 |
2023-08-11 |
rat |
| M M Mesulam, C Geul. Overlap between acetylcholinesterase-rich and choline acetyltransferase-positive (cholinergic) axons in human cerebral cortex. Brain research. vol 577. issue 1. 1992-10-09. PMID:1521137. |
overlap between acetylcholinesterase-rich and choline acetyltransferase-positive (cholinergic) axons in human cerebral cortex. |
1992-10-09 |
2023-08-11 |
human |
| M M Mesulam, C Geul. Overlap between acetylcholinesterase-rich and choline acetyltransferase-positive (cholinergic) axons in human cerebral cortex. Brain research. vol 577. issue 1. 1992-10-09. PMID:1521137. |
the distribution of acetylcholinesterase-rich axons was compared to that of choline acetyltransferase-positive (cholinergic) axons in 28 major cytoarchitectonic divisions of the adult human cerebral cortex. |
1992-10-09 |
2023-08-11 |
human |