| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Perini, M Brunetti, L Parnetti, G E De Medio, G Trovarelli, S Banfi, L Dorigotti, A Gait. The effect of oxiracetam treatment on alterations of lipid metabolism in brain areas from spontaneously hypertensive rats. Pharmacological research. vol 21. issue 3. 1989-08-17. PMID:2748513. |
we have now assayed the incorporation of labelled choline, ethanolamine, glycerol and arachidonic acid into the phospholipids from the cortex and hippocampus of shr-water and shr-nacl at different time intervals from injection into the lateral ventricle of the brain. |
1989-08-17 |
2023-08-11 |
rat |
| S Perini, M Brunetti, L Parnetti, G E De Medio, G Trovarelli, S Banfi, L Dorigotti, A Gait. The effect of oxiracetam treatment on alterations of lipid metabolism in brain areas from spontaneously hypertensive rats. Pharmacological research. vol 21. issue 3. 1989-08-17. PMID:2748513. |
a noticeable decrease of both choline and arachidonate specific activity (sa) in the phospholipids was found in the cortex and hippocampus (where the effect is most evident) from shr-nacl. |
1989-08-17 |
2023-08-11 |
rat |
| R Schliebs, M Zivin, J Steinbach, T Roth. Changes in cholinergic but not in GABAergic markers in amygdala, piriform cortex, and nucleus basalis of the rat brain following systemic administration of kainic acid. Journal of neurochemistry. vol 53. issue 1. 1989-07-13. PMID:2542459. |
sodium-dependent high-affinity choline uptake into cholinergic nerve terminals was decreased in the piriform cortex (by 25%) and amygdala (by 24%) after kainic acid treatment. |
1989-07-13 |
2023-08-11 |
rat |
| A Horita, M A Carino, C Chin. Fentanyl produces cholinergically-mediated analeptic and EEG arousal effects in rats. Neuropharmacology. vol 28. issue 5. 1989-07-11. PMID:2566949. |
fentanyl also increased sodium-dependent high affinity uptake of choline activity in the hippocampus and cortex that had been depressed by the barbiturate. |
1989-07-11 |
2023-08-11 |
rat |
| D Curti, F Dagani, M R Galmozzi, F Marzatic. Effect of aging and acetyl-L-carnitine on energetic and cholinergic metabolism in rat brain regions. Mechanisms of ageing and development. vol 47. issue 1. 1989-07-03. PMID:2542702. |
in synaptosomes, pyruvate dehydrogenase, choline acetyltransferase and acetylcholinesterase specific activity remained unchanged, but the high-affinity choline uptake decreased in cerebral cortex and striatum of 18-month-old rats. |
1989-07-03 |
2023-08-11 |
rat |
| D Curti, F Dagani, M R Galmozzi, F Marzatic. Effect of aging and acetyl-L-carnitine on energetic and cholinergic metabolism in rat brain regions. Mechanisms of ageing and development. vol 47. issue 1. 1989-07-03. PMID:2542702. |
acetyl-l-carnitine treatment increased the high-affinity choline uptake in cerebral cortex of 18-month-old rats. |
1989-07-03 |
2023-08-11 |
rat |
| Z Pittel, A Fisher, E Heldma. Cholinotoxicity induced by ethylcholine aziridinium ion after intracarotid and intracerebroventricular administration. Life sciences. vol 44. issue 20. 1989-06-30. PMID:2725177. |
high-affinity choline transport was reduced significantly 11 days after an icv injection of af64a in all the above mentioned brain regions, and recovered 60 days post injection in the cerebral cortex and in the corpus striatum but not in the hippocampus. |
1989-06-30 |
2023-08-11 |
rat |
| K Kinouchi, S Maeda, K Saito, R Inoki, K Fukumitsu, I Yoshiy. Effects of d- and l-pentazocine on the release and uptake of norepinephrine in rat brain cortex. Research communications in chemical pathology and pharmacology. vol 63. issue 2. 1989-06-06. PMID:2565594. |
both isomers inhibited the uptake of [3h]norepinephrine, [3h]dopamine and [3h]5-ht but not that of [3h]gaba and [3h]choline into synaptosomes prepared from the cortex. |
1989-06-06 |
2023-08-11 |
rat |
| K F Funk, J Schmid. [Cholinergic effects of nootropics]. Biomedica biochimica acta. vol 47. issue 4-5. 1989-04-25. PMID:3149192. |
a single dose of pramiracetam enhances the choline uptake in cortex and hippocampus. |
1989-04-25 |
2023-08-11 |
Not clear |
| A Lysakowski, B H Wainer, G Bruce, L B Hers. An atlas of the regional and laminar distribution of choline acetyltransferase immunoreactivity in rat cerebral cortex. Neuroscience. vol 28. issue 2. 1989-04-18. PMID:2646551. |
the distribution of cholinergic fibers in rat cortex was investigated using choline acetyl-transferase immunohistochemistry. |
1989-04-18 |
2023-08-11 |
rat |
| L G Miller, D J Greenblatt, R B Roy, F Lopez, L Wecke. Dietary choline intake modulates benzodiazepine receptor binding and gamma-aminobutyric acidA receptor function in mouse brain. The Journal of pharmacology and experimental therapeutics. vol 248. issue 1. 1989-03-03. PMID:2536422. |
choline supplementation significantly increased the in vivo binding of [3h]ro15-1788 to cortex and cerebellum by 19% and 24%, respectively, and in vitro studies in cortical membranes indicated a significant 36% increase in the maximal number of [3h]flunitrazepam binding sites without a change in affinity, as compared to basal controls. |
1989-03-03 |
2023-08-11 |
mouse |
| N A Muma, P P Rowell, G S Schult. Effects of long-term dietary choline and phosphatidylcholine administration on muscarinic receptors in aged mouse brain. Neurological research. vol 10. issue 3. 1989-02-28. PMID:2905774. |
choline levels were unaffected by the various diets, however phosphatidylcholine treatment resulted in an increase in phosphatidylcholine in the cortex and somewhat in the hippocampus. |
1989-02-28 |
2023-08-11 |
mouse |
| E B Grossman, S C Heber. Renal inner medullary choline dehydrogenase activity: characterization and modulation. The American journal of physiology. vol 256. issue 1 Pt 2. 1989-02-23. PMID:2643346. |
during hypernatremia, when betaine content of the inner medulla has been shown to increase 1.5-fold, choline dehydrogenase activity remains unchanged (or slightly increased), whereas enzyme activity in the cortex increases approximately 50%. |
1989-02-23 |
2023-08-11 |
rat |
| O U Scremin, D J Jende. Focal ischemia enhances choline output and decreases acetylcholine output from rat cerebral cortex. Stroke. vol 20. issue 1. 1989-02-22. PMID:2911840. |
focal ischemia enhances choline output and decreases acetylcholine output from rat cerebral cortex. |
1989-02-22 |
2023-08-11 |
rat |
| O U Scremin, D J Jende. Focal ischemia enhances choline output and decreases acetylcholine output from rat cerebral cortex. Stroke. vol 20. issue 1. 1989-02-22. PMID:2911840. |
we determined choline and acetylcholine output from the ischemic cerebral cortex by analyzing their concentrations in the fluid contained in cortical cups by gas chromatography-mass spectrometry. |
1989-02-22 |
2023-08-11 |
rat |
| P H Yance. Osmotic effectors in kidneys of xeric and mesic rodents: corticomedullary distributions and changes with water availability. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology. vol 158. issue 3. 1988-12-30. PMID:3057002. |
in animals kept without water for 4-6 days, sodium, urea, betaine and gpc + choline were found in gradients increasing from cortex to outer to inner medulla in all species, with perognathus having the highest levels. |
1988-12-30 |
2023-08-11 |
mouse |
| A Toumane, T Durkin, A Marighetto, D Galey, R Jaffar. Differential hippocampal and cortical cholinergic activation during the acquisition, retention, reversal and extinction of a spatial discrimination in an 8-arm radial maze by mice. Behavioural brain research. vol 30. issue 3. 1988-12-06. PMID:3178994. |
high-affinity choline uptake velocities in the hippocampus and cortex were analyzed, in parallel, at various periods during the acquisition, over 8 days, as were the subsequent retention, reversal and extinction of a spatial discrimination in an 8-arm radial maze. |
1988-12-06 |
2023-08-11 |
mouse |
| R L Bernays, L Heeb, M Cuenod, P Strei. Afferents to the rat red nucleus studied by means of D-[3H]aspartate, [3H]choline and non-selective tracers. Neuroscience. vol 26. issue 2. 1988-11-23. PMID:3173690. |
following application of [3h]choline and using an improved autoradiographic method, perikaryal labeling was massive within nucleus interpositus, while it was absent in dorsal raphé nucleus, cerebral cortex and zona incerta. |
1988-11-23 |
2023-08-11 |
rat |
| G V Johnson, M Simonato, R S Jop. Dose- and time-dependent hippocampal cholinergic lesions induced by ethylcholine mustard aziridinium ion: effects of nerve growth factor, GM1 ganglioside, and vitamin E. Neurochemical research. vol 13. issue 8. 1988-11-21. PMID:3173620. |
dose- and time-dependent hippocampal cholinergic lesions induced by ethylcholine mustard aziridinium ion: effects of nerve growth factor, gm1 ganglioside, and vitamin e. ethylcholine mustard aziridinium ion (ecma) was infused intracerebroventricularly (icv) to rats followed by measurement of two markers of presynaptic cholinergic neurons, choline acetyltransferase (chat) activity and high affinity choline transport (hacht), in the hippocampus and cortex. |
1988-11-21 |
2023-08-11 |
rat |
| V E Grimm, B Friede. Prenatal caffeine causes long lasting behavioral and neurochemical changes. The International journal of neuroscience. vol 41. issue 1-2. 1988-09-26. PMID:3410649. |
the neurochemical studies carried out at 2-3 months of age revealed an increase in choline uptake in hippocampus, mainly in the animals treated with the lower doses of caffeine and higher protein concentration (microgram/mg wet tissue) in the cortex or hippocampus of offspring exposed to the higher doses of caffeine. |
1988-09-26 |
2023-08-11 |
rat |