| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alessia Ligresti, Aniello Schiano Moriello, Katarzyna Starowicz, Isabel Matias, Simona Pisanti, Luciano De Petrocellis, Chiara Laezza, Giuseppe Portella, Maurizio Bifulco, Vincenzo Di Marz. Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma. The Journal of pharmacology and experimental therapeutics. vol 318. issue 3. 2006-10-10. PMID:16728591. |
antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma. |
2006-10-10 |
2023-08-12 |
mouse |
| Alessia Ligresti, Aniello Schiano Moriello, Katarzyna Starowicz, Isabel Matias, Simona Pisanti, Luciano De Petrocellis, Chiara Laezza, Giuseppe Portella, Maurizio Bifulco, Vincenzo Di Marz. Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma. The Journal of pharmacology and experimental therapeutics. vol 318. issue 3. 2006-10-10. PMID:16728591. |
we investigated the antitumor activities of other plant cannabinoids, i.e., cannabidiol, cannabigerol, cannabichromene, cannabidiol acid and thc acid, and assessed whether there is any advantage in using cannabis extracts (enriched in either cannabidiol or thc) over pure cannabinoids. |
2006-10-10 |
2023-08-12 |
mouse |
| Alessia Ligresti, Aniello Schiano Moriello, Katarzyna Starowicz, Isabel Matias, Simona Pisanti, Luciano De Petrocellis, Chiara Laezza, Giuseppe Portella, Maurizio Bifulco, Vincenzo Di Marz. Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma. The Journal of pharmacology and experimental therapeutics. vol 318. issue 3. 2006-10-10. PMID:16728591. |
at least for mda-mb-231 cells, however, our experiments indicate that cannabidiol effect is due to its capability of inducing apoptosis via: direct or indirect activation of cannabinoid cb(2) and vanilloid transient receptor potential vanilloid type-1 receptors and cannabinoid/vanilloid receptor-independent elevation of intracellular ca(2+) and reactive oxygen species. |
2006-10-10 |
2023-08-12 |
mouse |
| Anna Lisa Muntoni, Giuliano Pillolla, Miriam Melis, Simona Perra, Gian Luigi Gessa, Marco Pisti. Cannabinoids modulate spontaneous neuronal activity and evoked inhibition of locus coeruleus noradrenergic neurons. The European journal of neuroscience. vol 23. issue 9. 2006-10-06. PMID:16706846. |
intravenous injection of both the synthetic cannabinoid agonist, win55212-2, and the main psychoactive principle of cannabis, delta9-tetrahydrocannabinol, dose-dependently increased the firing rate of lc noradrenergic neurons, with win55212-2 being the most efficacious. |
2006-10-06 |
2023-08-12 |
rat |
| Robert J McKallip, Wentao Jia, Jerome Schlomer, James W Warren, Prakash S Nagarkatti, Mitzi Nagarkatt. Cannabidiol-induced apoptosis in human leukemia cells: A novel role of cannabidiol in the regulation of p22phox and Nox4 expression. Molecular pharmacology. vol 70. issue 3. 2006-09-28. PMID:16754784. |
in the current study, we examined the effects of the nonpsychoactive cannabinoid, cannabidiol, on the induction of apoptosis in leukemia cells. |
2006-09-28 |
2023-08-12 |
human |
| P Massi, A Vaccani, D Parolar. Cannabinoids, immune system and cytokine network. Current pharmaceutical design. vol 12. issue 24. 2006-09-25. PMID:16918439. |
studies on drug-abusing humans and animals, as well as in vitro models employing immune cell cultures, have shown that marijuana, natural and endogenous cannabinoid compounds are immunomodulators. |
2006-09-25 |
2023-08-12 |
Not clear |
| Annick Ménétrey, Marc Augsburger, Bernard Favrat, Marie A Pin, Laura E Rothuizen, Monique Appenzeller, Thierry Buclin, Patrice Mangin, Christian Girou. Assessment of driving capability through the use of clinical and psychomotor tests in relation to blood cannabinoids levels following oral administration of 20 mg dronabinol or of a cannabis decoction made with 20 or 60 mg Delta9-THC. Journal of analytical toxicology. vol 29. issue 5. 2006-09-22. PMID:16105257. |
assessment of driving capability through the use of clinical and psychomotor tests in relation to blood cannabinoids levels following oral administration of 20 mg dronabinol or of a cannabis decoction made with 20 or 60 mg delta9-thc. |
2006-09-22 |
2023-08-12 |
human |
| Annick Ménétrey, Marc Augsburger, Bernard Favrat, Marie A Pin, Laura E Rothuizen, Monique Appenzeller, Thierry Buclin, Patrice Mangin, Christian Girou. Assessment of driving capability through the use of clinical and psychomotor tests in relation to blood cannabinoids levels following oral administration of 20 mg dronabinol or of a cannabis decoction made with 20 or 60 mg Delta9-THC. Journal of analytical toxicology. vol 29. issue 5. 2006-09-22. PMID:16105257. |
forensic interpretation of cannabinoids blood concentrations were attempted using the models proposed by daldrup (cannabis influencing factor or cif) and huestis and coworkers. |
2006-09-22 |
2023-08-12 |
human |
| X Wang, D Dow-Edwards, V Anderson, H Minkoff, Y L Hur. Discrete opioid gene expression impairment in the human fetal brain associated with maternal marijuana use. The pharmacogenomics journal. vol 6. issue 4. 2006-09-18. PMID:16477274. |
the present study investigated the effects of in utero marijuana exposure on expression levels of opioid-related genes in the human fetal forebrain in light of the strong interaction between the cannabinoid and opioid systems. |
2006-09-18 |
2023-08-12 |
human |
| B Vidinský, P Gál, J Mojzi. [Different views on the association between cannabinoids and cancer]. Casopis lekaru ceskych. vol 145. issue 6. 2006-09-12. PMID:16835997. |
third, the results of the newest study focused on the association between cannabinoids use and cancer risk showed no significant association between increased cancer incidence and cannabinoids use and it does not depend on the amount of used cannabis. |
2006-09-12 |
2023-08-12 |
human |
| Suresh Sundra. Cannabis and neurodevelopment: implications for psychiatric disorders. Human psychopharmacology. vol 21. issue 4. 2006-08-31. PMID:16783814. |
the developing brain is susceptible to the effects of exogenous cannabinoids both during the perinatal period through maternal cannabis use and in young adolescent users. |
2006-08-31 |
2023-08-12 |
human |
| Suresh Sundra. Cannabis and neurodevelopment: implications for psychiatric disorders. Human psychopharmacology. vol 21. issue 4. 2006-08-31. PMID:16783814. |
further understanding how cannabinoids influence neurodevelopment will inform public debate about the health effects of cannabis but also open avenues in discerning how modulation of the endocannabinoid system may assist in the development of therapeutic tools for a variety of neuropsychiatric disorders. |
2006-08-31 |
2023-08-12 |
human |
| Soo Yeun Lee, Seung Min Oh, Kyu Hyuck Chun. Estrogenic effects of marijuana smoke condensate and cannabinoid compounds. Toxicology and applied pharmacology. vol 214. issue 3. 2006-08-24. PMID:16499939. |
estrogenic effects of marijuana smoke condensate and cannabinoid compounds. |
2006-08-24 |
2023-08-12 |
rat |
| Karina K Kedzior, Mathew T Martin-Iverso. Chronic cannabis use is associated with attention-modulated reduction in prepulse inhibition of the startle reflex in healthy humans. Journal of psychopharmacology (Oxford, England). vol 20. issue 4. 2006-08-18. PMID:16174673. |
the ppi was correlated with the duration of cannabis use but not with the concentration of cannabinoid metabolites in urine and the recency of cannabis use in the preceding 24 hours. |
2006-08-18 |
2023-08-12 |
Not clear |
| John C Ashton, Cynthia L Darlington, Paul F Smit. Co-distribution of the cannabinoid CB1 receptor and the 5-HT transporter in the rat amygdale. European journal of pharmacology. vol 537. issue 1-3. 2006-08-11. PMID:16624281. |
cannabis sometimes causes dysphoria rather than euphoria; however, evidence relating to the interaction between the cannabinoid and 5-hydroxtryptamine (5-ht) systems is limited, especially in areas of the brain such as the amygdale. |
2006-08-11 |
2023-08-12 |
rat |
| Alex Straiker, Ken Macki. Cannabinoids, electrophysiology, and retrograde messengers: challenges for the next 5 years. The AAPS journal. vol 8. issue 2. 2006-08-11. PMID:16796377. |
most of the behavioral effects of cannabis and its active ingredients, the cannabinoids (delta9thc being the most abundant of these), appear to be mediated by cannabinoid receptors. |
2006-08-11 |
2023-08-12 |
Not clear |
| C Giroud, M Augsburger, B Favrat, A Menetrey, M-A Pin, L-E Rothuizen, M Appenzeller, T Buclin, S Mathieu, V Castella, A Hazekamp, P Mangi. [Effects of oral cannabis and dronabinol on driving capacity]. Annales pharmaceutiques francaises. vol 64. issue 3. 2006-08-10. PMID:16710114. |
the cannabis influence factor (cif) which relies on the molar ratio of active and inactive cannabinoids in blood provided a good estimate of the fitness to drive. |
2006-08-10 |
2023-08-12 |
human |
| U Pagotto, C Cervino, V Vicennati, G Marsicano, B Lutz, R Pasqual. How many sites of action for endocannabinoids to control energy metabolism? International journal of obesity (2005). vol 30 Suppl 1. 2006-08-08. PMID:16570104. |
however, in the last few years, with the advanced understanding of the crucial role of the hypothalamic neuronal network in the regulation of appetite, several studies have also directed attention to the orexigenic role of the endocannabinoid system, substantiating the well known appetite stimulating properties of derivatives of cannabis sativa. |
2006-08-08 |
2023-08-12 |
Not clear |
| Spiro Pavlopoulos, Ganesh A Thakur, Spyros P Nikas, Alexandros Makriyanni. Cannabinoid receptors as therapeutic targets. Current pharmaceutical design. vol 12. issue 14. 2006-08-01. PMID:16712486. |
the cannabinoid receptors cb1 and cb2 are family a, g-protein coupled receptors that mediate the effects of cannabinoids, a class of compounds that are so named because the first members were isolates of the cannabis plant. |
2006-08-01 |
2023-08-12 |
Not clear |
| Erica J Carrier, John A Auchampach, Cecilia J Hillar. Inhibition of an equilibrative nucleoside transporter by cannabidiol: a mechanism of cannabinoid immunosuppression. Proceedings of the National Academy of Sciences of the United States of America. vol 103. issue 20. 2006-07-28. PMID:16672367. |
inhibition of an equilibrative nucleoside transporter by cannabidiol: a mechanism of cannabinoid immunosuppression. |
2006-07-28 |
2023-08-12 |
mouse |