| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Stéphane Vignot, Benjamin Besse, Thibault de la Motte Rouge, Christophe Massard, Jean-Philippe Spano, Laurent Karil. [Cannabis and cancer]. Bulletin du cancer. vol 93. issue 2. 2006-04-25. PMID:16517414. |
the two varieties of hemp, cannabis sativa and cannabis indica, contain about sixty compounds, named cannabinoids. |
2006-04-25 |
2023-08-12 |
Not clear |
| Stéphane Vignot, Benjamin Besse, Thibault de la Motte Rouge, Christophe Massard, Jean-Philippe Spano, Laurent Karil. [Cannabis and cancer]. Bulletin du cancer. vol 93. issue 2. 2006-04-25. PMID:16517414. |
this review of the literature analyses these questions with special concern on the carcinogenic role of cannabis, the potential antitumor effect of cannabinoids and the place of thc and its derivatives for supportive care in cancerology. |
2006-04-25 |
2023-08-12 |
Not clear |
| Grzegorz Kwolek, Agnieszka Zakrzeska, Hanna Kozłowska, Barbara Malinowsk. [Influence of anandamide, the endogenous agonist of cannabinoid receptors on the circulatory system]. Postepy higieny i medycyny doswiadczalnej (Online). vol 59. 2006-04-24. PMID:15928605. |
cannabinoids, the active ingredients of cannabis sativa, have been used by humans as hallucinogens and therapeutic agents for thousands of years. |
2006-04-24 |
2023-08-12 |
human |
| Bradley E Alge. Endocannabinoid identification in the brain: studies of breakdown lead to breakthrough, and there may be NO hope. Science's STKE : signal transduction knowledge environment. vol 2005. issue 309. 2006-04-21. PMID:16278487. |
endocannabinoids are a class of fatty acid derivatives defined by their ability to interact with the specific cannabinoid receptors that were originally identified as the targets of delta9-tetrahydocannabinol (delta9-thc), the psychoactive component of cannabis. |
2006-04-21 |
2023-08-12 |
Not clear |
| R G Pertwe. Pharmacological actions of cannabinoids. Handbook of experimental pharmacology. issue 168. 2006-04-19. PMID:16596770. |
in addition, more information is beginning to emerge about the pharmacological actions of the non-psychoactive plant cannabinoid, cannabidiol. |
2006-04-19 |
2023-08-12 |
Not clear |
| C W Vaughan, M J Christi. Retrograde signalling by endocannabinoids. Handbook of experimental pharmacology. issue 168. 2006-04-19. PMID:16596781. |
within the brain the marijuana constituent delta9-tetrahydrocannabinol (thc) produces its pharmacological actions by acting on cannabinoid cb1 receptors. |
2006-04-19 |
2023-08-12 |
Not clear |
| G A Cabral, A Staa. Effects on the immune system. Handbook of experimental pharmacology. issue 168. 2006-04-19. PMID:16596782. |
marijuana and other exogenous cannabinoids alter immune function and decrease host resistance to microbial infections in experimental animal models and in vitro. |
2006-04-19 |
2023-08-12 |
Not clear |
| G A Cabral, A Staa. Effects on the immune system. Handbook of experimental pharmacology. issue 168. 2006-04-19. PMID:16596782. |
while marijuana and various cannabinoids have been documented to alter immune functions in vitro and in experimental animals, no controlled longitudinal epidemiological studies have yet definitively correlated immunosuppressive effects with increased incidence of infections or immune disorders in humans. |
2006-04-19 |
2023-08-12 |
Not clear |
| M Maccarrone, T Wenge. Effects of cannabinoids on hypothalamic and reproductive function. Handbook of experimental pharmacology. issue 168. 2006-04-19. PMID:16596787. |
marijuana and cannabinoids have been shown to exert profound effects on hypothalamic regulatory functions and reproduction in both experimental animals and humans. |
2006-04-19 |
2023-08-12 |
human |
| M A Huesti. Pharmacokinetics and metabolism of the plant cannabinoids, delta9-tetrahydrocannabinol, cannabidiol and cannabinol. Handbook of experimental pharmacology. issue 168. 2006-04-19. PMID:16596792. |
pharmacokinetics and metabolism of the plant cannabinoids, delta9-tetrahydrocannabinol, cannabidiol and cannabinol. |
2006-04-19 |
2023-08-12 |
human |
| M A Huesti. Pharmacokinetics and metabolism of the plant cannabinoids, delta9-tetrahydrocannabinol, cannabidiol and cannabinol. Handbook of experimental pharmacology. issue 168. 2006-04-19. PMID:16596792. |
delta9-tetrahydrocannabinol, the primary psychoactive component of cannabis sativa, and its metabolites 11-hydroxy-delta9-tetrahydrocannabinol and 11-nor-9-carboxy-tetrahydrocannabinol are the focus of this chapter, although cannabidiol and cannabinol, two other cannabinoids with an interesting array of activities, will also be reviewed. |
2006-04-19 |
2023-08-12 |
human |
| P Robso. Human studies of cannabinoids and medicinal cannabis. Handbook of experimental pharmacology. issue 168. 2006-04-19. PMID:16596794. |
human studies of cannabinoids and medicinal cannabis. |
2006-04-19 |
2023-08-12 |
human |
| Keizo Wak. [Endogenous cannabinoid receptor ligands--anandamide and 2-arachidonoylglycerol]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 126. issue 2. 2006-04-17. PMID:16462096. |
delta(9)-tetrahydrocannabinol, major psychoactive component of marijuana, has been shown to interact with specific cannabinoid receptors, thereby eliciting a variety of pharmacological responses in experimental animals and human. |
2006-04-17 |
2023-08-12 |
human |
| W K Scholte. [The mechanism of action of cannabis and cannabinoids]. Nederlands tijdschrift voor geneeskunde. vol 150. issue 3. 2006-04-13. PMID:16463612. |
[the mechanism of action of cannabis and cannabinoids]. |
2006-04-13 |
2023-08-12 |
Not clear |
| Janne Mannila, Tomi Järvinen, Kristiina Järvinen, Maarit Tarvainen, Pekka Jarh. Effects of RM-beta-CD on sublingual bioavailability of Delta9-tetrahydrocannabinol in rabbits. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. vol 26. issue 1. 2006-04-07. PMID:15955678. |
complexation of model cannabinoids, delta(9)-tetrahydrocannabinol (thc) and cannabidiol (cbd), with randomly methylated beta-cyclodextrin (rm-beta-cd) and hydroxypropyl-beta-cyclodextrin (hp-beta-cd), were studied by the phase-solubility method. |
2006-04-07 |
2023-08-12 |
Not clear |
| M Storr, B Yüce, B Gök. [Perspectives of cannabinoids in gastroenterology]. Zeitschrift fur Gastroenterologie. vol 44. issue 2. 2006-03-31. PMID:16456761. |
the possibility of cannabis abuse resulted in a worldwide prohibition and thus the temporary ending of the medical use of cannabinoids. |
2006-03-31 |
2023-08-12 |
Not clear |
| Mauro Maccarron. Fatty acid amide hydrolase: a potential target for next generation therapeutics. Current pharmaceutical design. vol 12. issue 6. 2006-03-31. PMID:16472164. |
anandamide (n-arachidonoylethanolamine; aea) and 2-arachidonoylglycerol are the main endogenous agonists of cannabinoid receptors, able to mimic several pharmacological effects of delta(9)-tetrahydrocannabinol, the active principle of cannabis sativa preparations like hashish and marijuana. |
2006-03-31 |
2023-08-12 |
human |
| Azza B El-Remessy, Mohamed Al-Shabrawey, Yousuf Khalifa, Nai-Tse Tsai, Ruth B Caldwell, Gregory I Lio. Neuroprotective and blood-retinal barrier-preserving effects of cannabidiol in experimental diabetes. The American journal of pathology. vol 168. issue 1. 2006-03-23. PMID:16400026. |
in the present study, the protective effects of a nonpsychotropic cannabinoid, cannabidiol (cbd), were examined in streptozotocin-induced diabetic rats after 1, 2, or 4 weeks. |
2006-03-23 |
2023-08-12 |
rat |
| F Musshoff, F Driever, K Lachenmeier, D W Lachenmeier, M Banger, B Made. Results of hair analyses for drugs of abuse and comparison with self-reports and urine tests. Forensic science international. vol 156. issue 2-3. 2006-03-23. PMID:16410161. |
in contrast to cocaine, hair lacks sensitivity as a detection agent for cannabinoids and a proof of cannabis use by means of hair analysis should include the sensitive detection of the metabolite thc carboxylic acid in the lower picogram range. |
2006-03-23 |
2023-08-12 |
Not clear |
| Lynne B Whan, Mhairi C L West, Neil McClure, Sheena E M Lewi. Effects of delta-9-tetrahydrocannabinol, the primary psychoactive cannabinoid in marijuana, on human sperm function in vitro. Fertility and sterility. vol 85. issue 3. 2006-03-21. PMID:16500334. |
effects of delta-9-tetrahydrocannabinol, the primary psychoactive cannabinoid in marijuana, on human sperm function in vitro. |
2006-03-21 |
2023-08-12 |
human |