| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marie Velenovská, Zdenek Fisa. Effect of cannabinoids on platelet serotonin uptake. Addiction biology. vol 12. issue 2. 2007-08-17. PMID:17508987. |
the effect of delta(9)-tetrahydrocannabinol (delta(9)-thc), endocannabinoid anandamide and synthetic cannabinoid receptor agonist win 55,212-2 on platelet serotonin uptake and membrane microviscosity was examined in 19 marijuana smokers and 20 controls. |
2007-08-17 |
2023-08-12 |
Not clear |
| Futoshi Taura, Supaart Sirikantaramas, Yoshinari Shoyama, Kazuyoshi Yoshikai, Yukihiro Shoyama, Satoshi Morimot. Cannabidiolic-acid synthase, the chemotype-determining enzyme in the fiber-type Cannabis sativa. FEBS letters. vol 581. issue 16. 2007-08-16. PMID:17544411. |
cannabidiolic-acid (cbda) synthase is the enzyme that catalyzes oxidative cyclization of cannabigerolic-acid into cbda, the dominant cannabinoid constituent of the fiber-type cannabis sativa. |
2007-08-16 |
2023-08-12 |
Not clear |
| Futoshi Taura, Supaart Sirikantaramas, Yoshinari Shoyama, Kazuyoshi Yoshikai, Yukihiro Shoyama, Satoshi Morimot. Cannabidiolic-acid synthase, the chemotype-determining enzyme in the fiber-type Cannabis sativa. FEBS letters. vol 581. issue 16. 2007-08-16. PMID:17544411. |
the structural and functional properties of cbda synthase are quite similar to those of tetrahydrocannabinolic-acid (thca) synthase, which is responsible for the biosynthesis of thca, the major cannabinoid in drug-type cannabis plants. |
2007-08-16 |
2023-08-12 |
Not clear |
| Mitch Earleywine, Sara Smucker Barnwel. Decreased respiratory symptoms in cannabis users who vaporize. Harm reduction journal. vol 4. 2007-08-10. PMID:17437626. |
vaporizers heat cannabis to release active cannabinoids, but remain cool enough to avoid the smoke and toxins associated with combustion. |
2007-08-10 |
2023-08-12 |
human |
| Tong-Rong Jan, Shu-Ting Su, Hsin-Ying Wu, Mei-Hsiu Lia. Suppressive effects of cannabidiol on antigen-specific antibody production and functional activity of splenocytes in ovalbumin-sensitized BALB/c mice. International immunopharmacology. vol 7. issue 6. 2007-08-06. PMID:17466911. |
because the immune system has been widely demonstrated to be affected by psychoactive cannabinoids, such as delta(9)-tetrahydrocannabinol, the objective of the present studies is to investigate the immunomodulatory effect of cbd, the major non-psychoactive cannabinoid in marijuana. |
2007-08-06 |
2023-08-12 |
mouse |
| Margaret Hane. Opioid antagonism of cannabinoid effects: differences between marijuana smokers and nonmarijuana smokers. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 6. 2007-07-27. PMID:17091128. |
opioid antagonism of cannabinoid effects: differences between marijuana smokers and nonmarijuana smokers. |
2007-07-27 |
2023-08-12 |
human |
| Gerold F Kauert, Johannes G Ramaekers, Erhard Schneider, Manfred R Moeller, Stefan W Toenne. Pharmacokinetic properties of delta9-tetrahydrocannabinol in serum and oral fluid. Journal of analytical toxicology. vol 31. issue 5. 2007-07-27. PMID:17579974. |
in a study on the effects of smoked cannabis (18.2 +/- 2.8 mg as low and 36.5 +/- 5.6 mg as high dose) paired blood and oral fluid samples were collected from 10 study participants up to 6 h after smoking and analyzed for the cannabinoids delta(9)-tetrahydrocannabinol (thc), 11-hydroxy-thc (thc-oh) and 11-nor-9-carboxy-thc (thca) using gas chromatography-mass spectrometry. |
2007-07-27 |
2023-08-12 |
human |
| Sandra B Grauwiler, André Scholer, Jürgen Drew. Development of a LC/MS/MS method for the analysis of cannabinoids in human EDTA-plasma and urine after small doses of Cannabis sativa extracts. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. vol 850. issue 1-2. 2007-07-24. PMID:17236827. |
development of a lc/ms/ms method for the analysis of cannabinoids in human edta-plasma and urine after small doses of cannabis sativa extracts. |
2007-07-24 |
2023-08-12 |
human |
| Sandra B Grauwiler, André Scholer, Jürgen Drew. Development of a LC/MS/MS method for the analysis of cannabinoids in human EDTA-plasma and urine after small doses of Cannabis sativa extracts. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. vol 850. issue 1-2. 2007-07-24. PMID:17236827. |
the method was successfully applied to the determination of cannabinoids in human plasma and human urine after administration of delta(9)-tetrahydrocannabinol or cannabis sativa extracts. |
2007-07-24 |
2023-08-12 |
human |
| Kenneth E Ugen, Susan B Nylan. Injecting drugs of abuse and immunity: implications for HIV vaccine testing and efficacy. Springer seminars in immunopathology. vol 28. issue 3. 2007-07-20. PMID:17109182. |
a number of agents including cannabinoids (marijuana), cocaine opiates, amphetamines, nicotine and alcohol were demonstrated to have potentially adverse effects on the susceptibility to infections, mediated most likely, by adverse effects on immunity. |
2007-07-20 |
2023-08-12 |
Not clear |
| Marilyn A Huestis, Richard A Gustafson, Eric T Moolchan, Allan Barnes, James A Bourland, Stacy A Sweeney, Eugene F Hayes, Patrick M Carpenter, Michael L Smit. Cannabinoid concentrations in hair from documented cannabis users. Forensic science international. vol 169. issue 2-3. 2007-07-19. PMID:16963215. |
cannabinoid concentrations in hair from documented cannabis users. |
2007-07-19 |
2023-08-12 |
human |
| Duncan Wallace, Ana-Louise Martin, Bianca Par. Cannabinoid hyperemesis: marijuana puts patients in hot water. Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists. vol 15. issue 2. 2007-07-10. PMID:17464661. |
cannabinoid hyperemesis: marijuana puts patients in hot water. |
2007-07-10 |
2023-08-12 |
Not clear |
| Duncan Wallace, Ana-Louise Martin, Bianca Par. Cannabinoid hyperemesis: marijuana puts patients in hot water. Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists. vol 15. issue 2. 2007-07-10. PMID:17464661. |
this paper describes a case of cannabinoid hyperemesis, a curious, emerging condition associated with long-term cannabis abuse. |
2007-07-10 |
2023-08-12 |
Not clear |
| Alexander F Hoffman, Murat Oz, Ruiqin Yang, Aron H Lichtman, Carl R Lupic. Opposing actions of chronic Delta9-tetrahydrocannabinol and cannabinoid antagonists on hippocampal long-term potentiation. Learning & memory (Cold Spring Harbor, N.Y.). vol 14. issue 1-2. 2007-07-03. PMID:17202425. |
memory deficits produced by marijuana arise partly via interaction of the psychoactive component, delta(9)-tetrahydrocannabinol (delta(9)-thc), with cannabinoid receptors in the hippocampus. |
2007-07-03 |
2023-08-12 |
rat |
| Kazuhide Hayakawa, Kenichi Mishima, Masanori Nozako, Mai Hazekawa, Ayumi Ogata, Masayuki Fujioka, Kazuhiko Harada, Shohei Mishima, Kensuke Orito, Nobuaki Egashira, Katunori Iwasaki, Michihiro Fujiwar. Delta9-tetrahydrocannabinol (Delta9-THC) prevents cerebral infarction via hypothalamic-independent hypothermia. Life sciences. vol 80. issue 16. 2007-06-28. PMID:17289082. |
delta(9)-tetrahydrocannabinol (delta(9)-thc), a primary psychoactive constituent of cannabis, has been reported to act as a neuroprotectant via the cannabinoid cb(1) receptor. |
2007-06-28 |
2023-08-12 |
mouse |
| A Fogarty, P Rawstorne, G Prestage, J Crawford, J Grierson, S Kippa. Marijuana as therapy for people living with HIV/AIDS: social and health aspects. AIDS care. vol 19. issue 2. 2007-06-28. PMID:17364413. |
further research might consider possible interactions between cannabinoids and antiretroviral treatments, potential use of oral thc and the difficulties faced by clinicians and plwha in discussing marijuana in the current legal context. |
2007-06-28 |
2023-08-12 |
human |
| Christian C Felder, Amy K Dickason-Chesterfield, Steven A Moor. Cannabinoids biology: the search for new therapeutic targets. Molecular interventions. vol 6. issue 3. 2007-06-22. PMID:16809476. |
cannabinoids, in the form of marijuana plant extracts, have been used for thousands of years for a wide variety of medical conditions, ranging from general malaise and mood disorders to more specific ailments, such as pain, nausea, and muscle spasms. |
2007-06-22 |
2023-08-12 |
Not clear |
| Christian C Felder, Amy K Dickason-Chesterfield, Steven A Moor. Cannabinoids biology: the search for new therapeutic targets. Molecular interventions. vol 6. issue 3. 2007-06-22. PMID:16809476. |
the discovery of tetrahydrocannabinol, the active principal in marijuana, and the identification and cloning of two cannabinoid receptors (i.e., cb1 and cb2) has subsequently led to biomedical appreciation for a family of endocannabinoid lipid transmitters. |
2007-06-22 |
2023-08-12 |
Not clear |
| Marcello Solinas, Maria Scherma, Liana Fattore, Jessica Stroik, Carrie Wertheim, Gianluigi Tanda, Walter Fratta, Steven R Goldber. Nicotinic alpha 7 receptors as a new target for treatment of cannabis abuse. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 21. 2007-06-22. PMID:17522306. |
in rats, systemic administration of the selective alpha7 nicotinic acetylcholine receptor antagonist methyllycaconitine (mla), but not the selective heteromeric non-alpha7 nicotinic acetylcholine receptor antagonist dihydrobetaerythroidine, (1) antagonized the discriminative effects of delta-9-tetrahydrocannabinol (thc), the main active ingredient in cannabis, (2) reduced intravenous self-administration of the synthetic cannabinoid cb1 receptor agonist win55,212-2 [(r)-(+)-[2,3-dihydro-5-methyl-3[(4-morpholinyl)methyl]pyrrolo[1,2,3-de]-1,4-benzoxazinyl]-(1-naphthalenyl)methanone, mesylate salt], and (3) decreased thc-induced dopamine elevations in the shell of the nucleus accumbens. |
2007-06-22 |
2023-08-12 |
rat |
| Marcello Solinas, Maria Scherma, Liana Fattore, Jessica Stroik, Carrie Wertheim, Gianluigi Tanda, Walter Fratta, Steven R Goldber. Nicotinic alpha 7 receptors as a new target for treatment of cannabis abuse. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 21. 2007-06-22. PMID:17522306. |
importantly, mla reversed the effects of cannabinoids at doses that did not produce depressant or toxic effects, further pointing to alpha7 nicotinic antagonists as potentially useful agents in the treatment of cannabis abuse in humans. |
2007-06-22 |
2023-08-12 |
rat |