| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gisela Skopp, Peter Strohbeck-Kuehner, Karl Mann, Derik Herman. Deposition of cannabinoids in hair after long-term use of cannabis. Forensic science international. vol 170. issue 1. 2007-10-18. PMID:17098389. |
the present investigation was aimed at a possible relationship between the cannabinoid concentration in hair and the cumulative dose in regular users of cannabis. |
2007-10-18 |
2023-08-12 |
human |
| Gisela Skopp, Peter Strohbeck-Kuehner, Karl Mann, Derik Herman. Deposition of cannabinoids in hair after long-term use of cannabis. Forensic science international. vol 170. issue 1. 2007-10-18. PMID:17098389. |
cannabinoids were present in any hair sample of cannabis users, but were not detectable in control specimens. |
2007-10-18 |
2023-08-12 |
human |
| Gisela Skopp, Peter Strohbeck-Kuehner, Karl Mann, Derik Herman. Deposition of cannabinoids in hair after long-term use of cannabis. Forensic science international. vol 170. issue 1. 2007-10-18. PMID:17098389. |
the concentration of major cannabinoids (sum of thc, cbd and cbn) was significantly correlated to either the reported cumulative cannabis dose during the last 3 months or to the cannabis use during the last 3 months estimated from the daily dose and the frequency per year (r=0.68 or 0.71, p=0.023 or 0.014). |
2007-10-18 |
2023-08-12 |
human |
| Paul F Smit. Symptomatic treatment of multiple sclerosis using cannabinoids: recent advances. Expert review of neurotherapeutics. vol 7. issue 9. 2007-10-18. PMID:17868014. |
a number of different cannabinoids have been used, including: delta9-tetrahydrocannabinol (thc) itself; the synthetic delta9-thc, dronabinol; a 1:1 ratio of delta9-thc:cannabidiol (sativex); and the synthetic delta9-thc metabolites ct-3 and nabilone. |
2007-10-18 |
2023-08-12 |
Not clear |
| Margaret Haney, Erik W Gunderson, Judith Rabkin, Carl L Hart, Suzanne K Vosburg, Sandra D Comer, Richard W Folti. Dronabinol and marijuana in HIV-positive marijuana smokers. Caloric intake, mood, and sleep. Journal of acquired immune deficiency syndromes (1999). vol 45. issue 5. 2007-10-10. PMID:17589370. |
individuals with hiv constitute the largest group using cannabinoids for medicinal reasons; yet, no studies have directly compared the tolerability and efficacy of smoked marijuana and oral dronabinol maintenance in hiv-positive marijuana smokers. |
2007-10-10 |
2023-08-12 |
Not clear |
| Andrés Ozaita, Emma Puighermanal, Rafael Maldonad. Regulation of PI3K/Akt/GSK-3 pathway by cannabinoids in the brain. Journal of neurochemistry. vol 102. issue 4. 2007-10-04. PMID:17484726. |
delta9-tetrahydrocannabinol (thc), the main psychoactive component in cannabis sativa preparations, exerts its central effects mainly through the g-protein coupled receptor cb1, a component of the endocannabinoid system. |
2007-10-04 |
2023-08-12 |
mouse |
| Thomas W Klein, Catherine A Newto. Therapeutic potential of cannabinoid-based drugs. Advances in experimental medicine and biology. vol 601. 2007-10-03. PMID:17713029. |
cannabinoid-based drugs modeled on cannabinoids originally isolated from marijuana are now known to significantly impact the functioning of the endocannabinoid system of mammals. |
2007-10-03 |
2023-08-12 |
human |
| Sevda Dirikoc, Suzette A Priola, Mathieu Marella, Nicole Zsürger, Joëlle Chabr. Nonpsychoactive cannabidiol prevents prion accumulation and protects neurons against prion toxicity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 36. 2007-10-02. PMID:17804615. |
here, we report that the nonpsychoactive cannabis constituent cannabidiol (cbd) inhibited prpres accumulation in both mouse and sheep scrapie-infected cells, whereas other structurally related cannabinoid analogs were either weak inhibitors or noninhibitory. |
2007-10-02 |
2023-08-12 |
mouse |
| Giulio G Mucciol. Blocking the cannabinoid receptors: drug candidates and therapeutic promises. Chemistry & biodiversity. vol 4. issue 8. 2007-09-28. PMID:17712820. |
the physiological effects of cannabis sativa (cannabis) and a throughout study of the endocannabinoid system allowed for the identification of several pathophysiological conditions--including obesity, dyslipidemia, addictions, inflammation, and allergies--in which blocking the cannabinoid receptors might be beneficial. |
2007-09-28 |
2023-08-12 |
Not clear |
| Daniele De Filippis, Annapina Russo, Daniela De Stefano, Maria Chiara Maiuri, Giuseppe Esposito, Maria Pia Cinelli, Concetta Pietropaolo, Rosa Carnuccio, Giulia Russo, Teresa Iuvon. Local administration of WIN 55,212-2 reduces chronic granuloma-associated angiogenesis in rat by inhibiting NF-kappaB activation. Journal of molecular medicine (Berlin, Germany). vol 85. issue 6. 2007-09-21. PMID:17447045. |
cannabinoids (cbs) from cannabis sativa l. exert a large number of biological effects including anti-inflammatory and anti-angiogenic effects. |
2007-09-21 |
2023-08-12 |
human |
| Elda Del Giudice, Luciano Rinaldi, Marzia Passarotto, Fabrizio Facchinetti, Antonello D'Arrigo, Adriano Guiotto, Maurizio Dalle Carbonare, Leontino Battistin, Alberta Leo. Cannabidiol, unlike synthetic cannabinoids, triggers activation of RBL-2H3 mast cells. Journal of leukocyte biology. vol 81. issue 6. 2007-09-17. PMID:17339608. |
cannabidiol, unlike synthetic cannabinoids, triggers activation of rbl-2h3 mast cells. |
2007-09-17 |
2023-08-12 |
rat |
| Elda Del Giudice, Luciano Rinaldi, Marzia Passarotto, Fabrizio Facchinetti, Antonello D'Arrigo, Adriano Guiotto, Maurizio Dalle Carbonare, Leontino Battistin, Alberta Leo. Cannabidiol, unlike synthetic cannabinoids, triggers activation of RBL-2H3 mast cells. Journal of leukocyte biology. vol 81. issue 6. 2007-09-17. PMID:17339608. |
cannabidiol (cbd), a prominent psychoinactive component of cannabis with negligible affinity for known cannabinoid receptors, exerts numerous pharmacological actions, including anti-inflammatory and immunosuppressive effects, the underlying mechanisms of which remain unclear. |
2007-09-17 |
2023-08-12 |
rat |
| Maximilian Peters, Natalya M Koga. HU-331: a cannabinoid quinone, with uncommon cytotoxic properties and low toxicity. Expert opinion on investigational drugs. vol 16. issue 9. 2007-09-14. PMID:17714026. |
out of these molecules the quinone of cannabidiol--the most abundant non-psychoactive cannabinoid in cannabis sativa--has shown the highest cytotoxicity. |
2007-09-14 |
2023-08-12 |
mouse |
| Satoshi Morimoto, Yumi Tanaka, Kaori Sasaki, Hiroyuki Tanaka, Tomohide Fukamizu, Yoshinari Shoyama, Yukihiro Shoyama, Futoshi Taur. Identification and characterization of cannabinoids that induce cell death through mitochondrial permeability transition in Cannabis leaf cells. The Journal of biological chemistry. vol 282. issue 28. 2007-09-13. PMID:17513301. |
identification and characterization of cannabinoids that induce cell death through mitochondrial permeability transition in cannabis leaf cells. |
2007-09-13 |
2023-08-12 |
Not clear |
| Satoshi Morimoto, Yumi Tanaka, Kaori Sasaki, Hiroyuki Tanaka, Tomohide Fukamizu, Yoshinari Shoyama, Yukihiro Shoyama, Futoshi Taur. Identification and characterization of cannabinoids that induce cell death through mitochondrial permeability transition in Cannabis leaf cells. The Journal of biological chemistry. vol 282. issue 28. 2007-09-13. PMID:17513301. |
cannabinoids are secondary metabolites stored in capitate-sessile glands on leaves of cannabis sativa. |
2007-09-13 |
2023-08-12 |
Not clear |
| Mohanraj Rajesh, Partha Mukhopadhyay, Sándor Bátkai, György Haskó, Lucas Liaudet, Viktor R Drel, Irina G Obrosova, Pál Pache. Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption. American journal of physiology. Heart and circulatory physiology. vol 293. issue 1. 2007-09-12. PMID:17384130. |
a nonpsychoactive cannabinoid cannabidiol (cbd) has been shown to exert potent anti-inflammatory and antioxidant effects and has recently been reported to lower the incidence of diabetes in nonobese diabetic mice and to preserve the blood-retinal barrier in experimental diabetes. |
2007-09-12 |
2023-08-12 |
mouse |
| Supaart Sirikantaramas, Futoshi Taura, Satoshi Morimoto, Yukihiro Shoyam. Recent advances in Cannabis sativa research: biosynthetic studies and its potential in biotechnology. Current pharmaceutical biotechnology. vol 8. issue 4. 2007-09-11. PMID:17691992. |
cannabinoids, consisting of alkylresorcinol and monoterpene groups, are the unique secondary metabolites that are found only in cannabis sativa. |
2007-09-11 |
2023-08-12 |
Not clear |
| Supaart Sirikantaramas, Futoshi Taura, Satoshi Morimoto, Yukihiro Shoyam. Recent advances in Cannabis sativa research: biosynthetic studies and its potential in biotechnology. Current pharmaceutical biotechnology. vol 8. issue 4. 2007-09-11. PMID:17691992. |
tetrahydrocannabinol (thc), cannabidiol (cbd) and cannabichromene (cbc) are well known cannabinoids and their pharmacological properties have been extensively studied. |
2007-09-11 |
2023-08-12 |
Not clear |
| Guido Lastra-Lastra, Guido Lastra-Gonzalez, Camila Manriqu. The endocannabinoid network: insight into the regulation of the neuroendocrine and metabolic systems. Journal of the cardiometabolic syndrome. vol 2. issue 1. 2007-08-31. PMID:17684453. |
originating from early studies with cannabis sativa, the active compound of marijuana, there has been an impressive progress in the knowledge about the endocannabinoid network, leading to the identification of specific pathways that modulate feeding behavior. |
2007-08-31 |
2023-08-12 |
Not clear |
| Mitona Pujadas, Simona Pichini, Ester Civit, Elena Santamariña, Katherine Perez, Rafael de la Torr. A simple and reliable procedure for the determination of psychoactive drugs in oral fluid by gas chromatography-mass spectrometry. Journal of pharmaceutical and biomedical analysis. vol 44. issue 2. 2007-08-23. PMID:17395417. |
substances under investigation were: psychostimulant drugs (amphetamine, methamphetamine, 3,4-methylenedioxymethamphetamine, 3,4-methylenedioxiamphetamine, 3,4-methylenedioxy-n-ethylamphetamine, phentermine), cocaine and metabolites (benzoylecgonine, cocaethylene, and ecgonine methyl esther), cannabinoids (delta-9-tetrahydrocannabinol, 11-nor-9-carboxy-delta-9-tetrahydrocannabinol, 11-hydroxy-delta-9-tetrahydrocannabinol, cannabinol and cannabidiol), opiates (6-monoacetylmorphine, morphine and codeine), hypnotics (flurazepam, flunitrazepam, dipotassium chlorazepate, alprazolam, diazepam and oxazepam), antidepressant drugs (amitryptiline, paroxetine and sertraline), antipsychotic drugs (haloperidol, chlorpromazine and fluphenazine) chlormethiazole, loratidine, hydroxyzine, diphenhydramine, valproic acid and gabapentin. |
2007-08-23 |
2023-08-12 |
Not clear |