| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ethan B Russ. Clinical endocannabinoid deficiency (CECD): can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions? Neuro endocrinology letters. vol 29. issue 2. 2008-06-25. PMID:18404144. |
this study examines the concept of clinical endocannabinoid deficiency (cecd), and the prospect that it could underlie the pathophysiology of migraine, fibromyalgia, irritable bowel syndrome, and other functional conditions alleviated by clinical cannabis. |
2008-06-25 |
2023-08-12 |
Not clear |
| Radosław Rudź, Urszula Baranowska, Barbara Malinowsk. [Function of cannabinoids in heart failure]. Postepy higieny i medycyny doswiadczalnej (Online). vol 62. 2008-06-17. PMID:18464680. |
cannabinoids, substances derived from cannabis sativa, have been used by humans as therapeutic agents for thousands of years. |
2008-06-17 |
2023-08-12 |
Not clear |
| Luciano De Petrocellis, Vittorio Vellani, Aniello Schiano-Moriello, Pietro Marini, Pier Cosimo Magherini, Pierangelo Orlando, Vincenzo Di Marz. Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8. The Journal of pharmacology and experimental therapeutics. vol 325. issue 3. 2008-06-16. PMID:18354058. |
the plant cannabinoids (phytocannabinoids), cannabidiol (cbd), and delta(9)-tetrahydrocannabinol (thc) were previously shown to activate transient receptor potential channels of both vanilloid type 1 (trpv1) and ankyrin type 1 (trpa1), respectively. |
2008-06-16 |
2023-08-12 |
rat |
| Safwat A Ahmed, Samir A Ross, Desmond Slade, Mohamed M Radwan, Fazila Zulfiqar, Rae R Matsumoto, Yan-Tong Xu, Eddy Viard, Robert C Speth, Vardan T Karamyan, M A ElSohl. Cannabinoid ester constituents from high-potency Cannabis sativa. Journal of natural products. vol 71. issue 4. 2008-06-13. PMID:18303850. |
cannabinoid ester constituents from high-potency cannabis sativa. |
2008-06-13 |
2023-08-12 |
Not clear |
| Safwat A Ahmed, Samir A Ross, Desmond Slade, Mohamed M Radwan, Fazila Zulfiqar, Rae R Matsumoto, Yan-Tong Xu, Eddy Viard, Robert C Speth, Vardan T Karamyan, M A ElSohl. Cannabinoid ester constituents from high-potency Cannabis sativa. Journal of natural products. vol 71. issue 4. 2008-06-13. PMID:18303850. |
eleven new cannabinoid esters, together with three known cannabinoid acids and delta9-tetrahydrocannabinol ( delta9-thc ), were isolated from a high-potency variety of cannabis sativa. |
2008-06-13 |
2023-08-12 |
Not clear |
| Marisela Agudelo, Cathy Newton, Ray Widen, Tracy Sherwood, Liang Nong, Herman Friedman, Thomas W Klei. Cannabinoid receptor 2 (CB2) mediates immunoglobulin class switching from IgM to IgE in cultures of murine-purified B lymphocytes. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 3. issue 1. 2008-05-13. PMID:18247126. |
marijuana cannabinoid treatment increases th2 activity, and previous reports showed that b cells express the highest level of cb(2) mrna relative to other immune cells, suggesting that cannabinoids play a critical role in b cell activation and maturation. |
2008-05-13 |
2023-08-12 |
mouse |
| David J Potter, Peter Clark, Marc B Brow. Potency of delta 9-THC and other cannabinoids in cannabis in England in 2005: implications for psychoactivity and pharmacology. Journal of forensic sciences. vol 53. issue 1. 2008-05-08. PMID:18279244. |
potency of delta 9-thc and other cannabinoids in cannabis in england in 2005: implications for psychoactivity and pharmacology. |
2008-05-08 |
2023-08-12 |
Not clear |
| David J Potter, Peter Clark, Marc B Brow. Potency of delta 9-THC and other cannabinoids in cannabis in England in 2005: implications for psychoactivity and pharmacology. Journal of forensic sciences. vol 53. issue 1. 2008-05-08. PMID:18279244. |
gas chromatography was used to study the cannabinoid content ("potency") of illicit cannabis seized by police in england in 2004/5. |
2008-05-08 |
2023-08-12 |
Not clear |
| David J Potter, Peter Clark, Marc B Brow. Potency of delta 9-THC and other cannabinoids in cannabis in England in 2005: implications for psychoactivity and pharmacology. Journal of forensic sciences. vol 53. issue 1. 2008-05-08. PMID:18279244. |
in sinsemilla and imported herbal cannabis, the content of the antipsychotic cannabinoid cannabidiol (cbd) was extremely low. |
2008-05-08 |
2023-08-12 |
Not clear |
| David J Potter, Peter Clark, Marc B Brow. Potency of delta 9-THC and other cannabinoids in cannabis in England in 2005: implications for psychoactivity and pharmacology. Journal of forensic sciences. vol 53. issue 1. 2008-05-08. PMID:18279244. |
the increases in average thc content and relative popularity of sinsemilla cannabis, combined with the absence of the anti-psychotic cannabinoid cbd, suggest that the current trends in cannabis use pose an increasing risk to those users susceptible to the harmful psychological effects associated with high doses of thc. |
2008-05-08 |
2023-08-12 |
Not clear |
| Zsuzsanna Sidló, Patricia H Reggio, Margaret E Ric. Inhibition of striatal dopamine release by CB1 receptor activation requires nonsynaptic communication involving GABA, H2O2, and KATP channels. Neurochemistry international. vol 52. issue 1-2. 2008-05-05. PMID:17767979. |
the main psychoactive component of marijuana, delta9-tetrahydrocannabinol (thc), acts in the cns via type 1 cannabinoid receptors (cb1rs). |
2008-05-05 |
2023-08-12 |
mouse |
| H P Huemer, A Himmelreich, B Hönlinger, M Pavlic, K Eisendle, R Höpfl, W Rabl, C-P Czern. "Recreational" drug abuse associated with failure to mount a proper antibody response after a generalised orthopoxvirus infection. Infection. vol 35. issue 6. 2008-05-01. PMID:17917699. |
the patient had been hospitalised for alcohol and cannabis intoxication 2 months prior to the orthopoxvirus infection and high levels of cannabinoids have been found repeatedly in the urine and upon one occasion also benzodiazepines. |
2008-05-01 |
2023-08-12 |
Not clear |
| M E Page, V C Oropeza, E J Van Bockstael. Local administration of a cannabinoid agonist alters norepinephrine efflux in the rat frontal cortex. Neuroscience letters. vol 431. issue 1. 2008-05-01. PMID:18055114. |
delta(9)-tetrahydrocannabinol, the main psychoactive ingredient in marijuana, activates specific cannabinoid (cb) receptors to exert complex actions on modulatory neurotransmitters involved in attention and cognition. |
2008-05-01 |
2023-08-12 |
rat |
| Gisela Skopp, Lucia Pötsc. Cannabinoid concentrations in spot serum samples 24-48 hours after discontinuation of cannabis smoking. Journal of analytical toxicology. vol 32. issue 2. 2008-04-22. PMID:18334100. |
cannabinoid concentrations in spot serum samples 24-48 hours after discontinuation of cannabis smoking. |
2008-04-22 |
2023-08-12 |
Not clear |
| Cristina Blázquez, Arkaitz Carracedo, María Salazar, Mar Lorente, Ainara Egia, Luis González-Feria, Amador Haro, Guillermo Velasco, Manuel Guzmá. Down-regulation of tissue inhibitor of metalloproteinases-1 in gliomas: a new marker of cannabinoid antitumoral activity? Neuropharmacology. vol 54. issue 1. 2008-04-18. PMID:17675107. |
cannabinoids, the active components of cannabis sativa l. and their derivatives, inhibit tumor growth in laboratory animals by inducing apoptosis of tumor cells and inhibiting tumor angiogenesis. |
2008-04-18 |
2023-08-12 |
mouse |
| Natalya M Kogan, Raphael Mechoula. Cannabinoids in health and disease. Dialogues in clinical neuroscience. vol 9. issue 4. 2008-04-11. PMID:18286801. |
despite the mild addiction to cannabis and the possible enhancement of addiction to other substances of abuse, when combined with cannabis, the therapeutic value of cannabinoids is too high to be put aside. |
2008-04-11 |
2023-08-12 |
Not clear |
| Cristina Blázquez, María Salazar, Arkaitz Carracedo, Mar Lorente, Ainara Egia, Luis González-Feria, Amador Haro, Guillermo Velasco, Manuel Guzmá. Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression. Cancer research. vol 68. issue 6. 2008-04-09. PMID:18339876. |
cannabinoids, the active components of cannabis sativa l. and their derivatives, inhibit tumor growth in laboratory animals by inducing apoptosis of tumor cells and impairing tumor angiogenesis. |
2008-04-09 |
2023-08-12 |
mouse |
| David Moir, William S Rickert, Genevieve Levasseur, Yolande Larose, Rebecca Maertens, Paul White, Suzanne Desjardin. A comparison of mainstream and sidestream marijuana and tobacco cigarette smoke produced under two machine smoking conditions. Chemical research in toxicology. vol 21. issue 2. 2008-04-08. PMID:18062674. |
there have been only limited examinations of marijuana smoke, including for cannabinoid content and for tar generation. |
2008-04-08 |
2023-08-12 |
Not clear |
| R G Pertwe. The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin. British journal of pharmacology. vol 153. issue 2. 2008-04-02. PMID:17828291. |
the diverse cb1 and cb2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin. |
2008-04-02 |
2023-08-12 |
Not clear |
| R G Pertwe. The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin. British journal of pharmacology. vol 153. issue 2. 2008-04-02. PMID:17828291. |
cannabis sativa is the source of a unique set of compounds known collectively as plant cannabinoids or phytocannabinoids. |
2008-04-02 |
2023-08-12 |
Not clear |