| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Frid. Multiple roles for the endocannabinoid system during the earliest stages of life: pre- and postnatal development. Journal of neuroendocrinology. vol 20 Suppl 1. 2008-07-18. PMID:18426504. |
manipulating the endocannabinoid system by pre- and/or postnatal administration of cannabinoids or maternal marijuana consumption, has significant, yet subtle effects on the offspring. |
2008-07-18 |
2023-08-12 |
mouse |
| N Battista, N Pasquariello, M Di Tommaso, M Maccarron. Interplay between endocannabinoids, steroids and cytokines in the control of human reproduction. Journal of neuroendocrinology. vol 20 Suppl 1. 2008-07-18. PMID:18426505. |
anandamide (n-arachidonoylethanolamine, aea) and 2-arachidonoylglycerol (2-ag) mimic delta(9)-tetrahydrocannabinol (thc), the psychoactive principle of cannabis sativa, by binding to both the brain-type (cb(1)) and the spleen-type (cb(2)) cannabinoid receptors. |
2008-07-18 |
2023-08-12 |
human |
| M Rossato, C Pagano, R Vetto. The cannabinoid system and male reproductive functions. Journal of neuroendocrinology. vol 20 Suppl 1. 2008-07-18. PMID:18426506. |
cannabinoids, the main active components of marijuana, have been shown to exert different adverse effects on male reproduction both in vertebrates and invertebrates. |
2008-07-18 |
2023-08-12 |
Not clear |
| R D Hosking, J P Zajice. Therapeutic potential of cannabis in pain medicine. British journal of anaesthesia. vol 101. issue 1. 2008-07-18. PMID:18515270. |
cannabinoids (cbs) are chemical compounds derived from cannabis. |
2008-07-18 |
2023-08-12 |
human |
| Ken Macki. Signaling via CNS cannabinoid receptors. Molecular and cellular endocrinology. vol 286. issue 1-2 Suppl 1. 2008-07-11. PMID:18336996. |
because of the prominent psychoactive effects of cannabis and its preparations, much research has focused on the actions of cannabinoids, the primary psychoactive components of cannabis, on neuronal function. |
2008-07-11 |
2023-08-12 |
Not clear |
| T Rubino, D Parolar. Long lasting consequences of cannabis exposure in adolescence. Molecular and cellular endocrinology. vol 286. issue 1-2 Suppl 1. 2008-07-11. PMID:18358595. |
therefore, the potential problems arising in relation to marijuana consumption in adolescence suggest that this developmental phase is a vulnerable period for persistent adverse effects of cannabinoids. |
2008-07-11 |
2023-08-12 |
Not clear |
| Marco Rossat. Endocannabinoids, sperm functions and energy metabolism. Molecular and cellular endocrinology. vol 286. issue 1-2 Suppl 1. 2008-07-11. PMID:18406050. |
cannabinoids, the main active components of marijuana, have been shown to exert different adverse effects on male reproduction both in vertebrates and invertebrates. |
2008-07-11 |
2023-08-12 |
Not clear |
| Ning Qin, Michael P Neeper, Yi Liu, Tasha L Hutchinson, Mary Lou Lubin, Christopher M Flore. TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 24. 2008-07-10. PMID:18550765. |
we also demonstrated that cannabidiol evoked a concentration-dependent release of calcitonin gene-related peptide (cgrp) from cultured rat dorsal root ganglion neurons in a cannabinoid receptor- and trpv1-independent manner. |
2008-07-10 |
2023-08-12 |
rat |
| Ziva D Cooper, Margaret Hane. Cannabis reinforcement and dependence: role of the cannabinoid CB1 receptor. Addiction biology. vol 13. issue 2. 2008-07-08. PMID:18279497. |
cannabis reinforcement and dependence: role of the cannabinoid cb1 receptor. |
2008-07-08 |
2023-08-12 |
Not clear |
| Ziva D Cooper, Margaret Hane. Cannabis reinforcement and dependence: role of the cannabinoid CB1 receptor. Addiction biology. vol 13. issue 2. 2008-07-08. PMID:18279497. |
this paper will review data implicating the cannabinoid cb1 receptor in regulating the behavioral effects of delta(9)-tetrahydrocannobinol (thc), the primary psychoactive component of cannabis, across a range of species. |
2008-07-08 |
2023-08-12 |
Not clear |
| Ziva D Cooper, Margaret Hane. Cannabis reinforcement and dependence: role of the cannabinoid CB1 receptor. Addiction biology. vol 13. issue 2. 2008-07-08. PMID:18279497. |
the behavioral effects that will be discussed include those that directly contribute to the maintenance of chronic marijuana smoking, such as reward, subjective effects, and the positive and negative reinforcing effects of marijuana, thc and synthetic cannabinoids. |
2008-07-08 |
2023-08-12 |
Not clear |
| Roger G Pertwe. Ligands that target cannabinoid receptors in the brain: from THC to anandamide and beyond. Addiction biology. vol 13. issue 2. 2008-07-08. PMID:18482430. |
a major finding--that (-)-trans-delta(9)-tetrahydrocannabinol (delta(9)-thc) is largely responsible for the psychotropic effects of cannabis--prompted research in the 1970s and 1980s that led to the discovery that this plant cannabinoid acts through at least two types of cannabinoid receptor, cb(1) and cb(2), and that delta(9)-thc and other compounds that target either or both of these receptors as agonists or antagonists have important therapeutic applications. |
2008-07-08 |
2023-08-12 |
Not clear |
| Miriam Schneide. Puberty as a highly vulnerable developmental period for the consequences of cannabis exposure. Addiction biology. vol 13. issue 2. 2008-07-08. PMID:18482434. |
considering the variety of maturational processes occurring in the endocannabinoid system during this critical period, it is not surprising that the still-developing brain might by highly susceptible to cannabis exposure. |
2008-07-08 |
2023-08-12 |
human |
| Miriam Schneide. Puberty as a highly vulnerable developmental period for the consequences of cannabis exposure. Addiction biology. vol 13. issue 2. 2008-07-08. PMID:18482434. |
these findings suggest that young people represent a highly vulnerable cannabis consumer group and that they run a higher risk than adult consumers of suffering from adverse consequences from cannabinoid exposure. |
2008-07-08 |
2023-08-12 |
human |
| F Markus Leweke, Dagmar Koeth. Cannabis and psychiatric disorders: it is not only addiction. Addiction biology. vol 13. issue 2. 2008-07-08. PMID:18482435. |
a possible neurobiological mechanism for the deleterious influence of cannabis use in scz has been suggested, involving the disruption of endogenous cannabinoid signaling and functioning. |
2008-07-08 |
2023-08-12 |
Not clear |
| F Markus Leweke, Dagmar Koeth. Cannabis and psychiatric disorders: it is not only addiction. Addiction biology. vol 13. issue 2. 2008-07-08. PMID:18482435. |
although the data on the influence of cannabis use on the development of major depression is controversial, cannabinoid compounds could display a new class of medication, as suggested by the antidepressive effects of the fatty acid amino hydrolase inhibitor urb597 in animal models. |
2008-07-08 |
2023-08-12 |
Not clear |
| Louisa Degenhardt, Wayne D Hal. The adverse effects of cannabinoids: implications for use of medical marijuana. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne. vol 178. issue 13. 2008-07-03. PMID:18559807. |
the adverse effects of cannabinoids: implications for use of medical marijuana. |
2008-07-03 |
2023-08-12 |
Not clear |
| Robert E Vann, Thomas F Gamage, Jonathan A Warner, Ericka M Marshall, Nathan L Taylor, Billy R Martin, Jenny L Wile. Divergent effects of cannabidiol on the discriminative stimulus and place conditioning effects of Delta(9)-tetrahydrocannabinol. Drug and alcohol dependence. vol 94. issue 1-3. 2008-06-27. PMID:18206320. |
cannabis sativa (marijuana plant) contains myriad cannabinoid compounds; yet, investigative attention has focused almost exclusively on delta(9)-tetrahydrocannabinol (thc), its primary psychoactive substituent. |
2008-06-27 |
2023-08-12 |
mouse |
| Robert E Vann, Thomas F Gamage, Jonathan A Warner, Ericka M Marshall, Nathan L Taylor, Billy R Martin, Jenny L Wile. Divergent effects of cannabidiol on the discriminative stimulus and place conditioning effects of Delta(9)-tetrahydrocannabinol. Drug and alcohol dependence. vol 94. issue 1-3. 2008-06-27. PMID:18206320. |
interest in modulation of thc's effects by these other cannabinoids (e.g., cannabidiol (cbd)) has been stimulated anew by recent approval by canada of sativex (a 1:1 dose ratio combination of cbd:thc) for the treatment of multiple sclerosis. |
2008-06-27 |
2023-08-12 |
mouse |
| Ethan B Russ. Clinical endocannabinoid deficiency (CECD): can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions? Neuro endocrinology letters. vol 29. issue 2. 2008-06-25. PMID:18404144. |
clinical endocannabinoid deficiency (cecd): can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions? |
2008-06-25 |
2023-08-12 |
Not clear |