| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fidelia Cascin. Investigations into the hypothesis of transgenic cannabis. Journal of forensic sciences. vol 57. issue 3. 2012-08-13. PMID:22211569. |
the unusual concentration of cannabinoids recently found in marijuana samples submitted to the forensic laboratory for chemical analysis prompted an investigation into whether genetic modifications have been made to the dna of cannabis sativa l. to increase its potency. |
2012-08-13 |
2023-08-12 |
Not clear |
| Zeland Muccio, Claudia Wöckel, Yan An, Glen P Jackso. Comparison of bulk and compound-specific δ13C isotope ratio analyses for the discrimination between cannabis samples. Journal of forensic sciences. vol 57. issue 3. 2012-08-13. PMID:22292792. |
five marijuana samples were compared using bulk isotope analysis compound-specific isotope ratio analysis of the extracted cannabinoids. |
2012-08-13 |
2023-08-12 |
Not clear |
| Zeland Muccio, Claudia Wöckel, Yan An, Glen P Jackso. Comparison of bulk and compound-specific δ13C isotope ratio analyses for the discrimination between cannabis samples. Journal of forensic sciences. vol 57. issue 3. 2012-08-13. PMID:22292792. |
all the measured cannabinoids showed significant depletion in (13)c relative to bulk isotope values; the isotope ratios for thc, cbn, and cannabidiol were on average 1.6‰, 1.7‰, and 2.2‰ more negative than the bulk values, respectively. |
2012-08-13 |
2023-08-12 |
Not clear |
| Derick Wad. Evaluation of the safety and tolerability profile of Sativex: is it reassuring enough? Expert review of neurotherapeutics. vol 12. issue 4 Suppl. 2012-08-10. PMID:22509986. |
however, in the case of sativex, a cannabinoid medicine containing the two main active ingredients of cannabis, δ-9-tetrahydrocannabinol and cannabidiol, the picture is somewhat clouded by preconceived views regarding the world's most widely used illicit drug, herbal cannabis. |
2012-08-10 |
2023-08-12 |
Not clear |
| Laurent Karila, Aymeric Petit, Olivier Cottencin, Sarah Coscas, Michel Reynau. [Synthetic drugs: the new low-cost landscape of drugs]. La Revue du praticien. vol 62. issue 5. 2012-07-31. PMID:22730798. |
synthetic cannabinoids are a psychoactive herbal and chemical product that, when used, mimics the effects of cannabis. |
2012-07-31 |
2023-08-12 |
human |
| Daniel Castellanos, Gabriel Thornto. Synthetic cannabinoid use: recognition and management. Journal of psychiatric practice. vol 18. issue 2. 2012-07-30. PMID:22418399. |
clinicians should suspect synthetic cannabinoid product use if a patient: 1) presents with signs and symptoms consistent with cannabis use, 2) has negative routine urine toxicology screens, 3) is in a situation in which his or her urine is being routinely monitored for illicit substance use, and/or 4) presents with otherwise unexplained sudden onset psychosis. |
2012-07-30 |
2023-08-12 |
Not clear |
| Patrizia Zaccagnino, Susanna D'Oria, Luigi Luciano Romano, Almerinda Di Venere, Anna Maria Sardanelli, Michele Loruss. The endocannabinoid 2-arachidonoylglicerol decreases calcium induced cytochrome c release from liver mitochondria. Journal of bioenergetics and biomembranes. vol 44. issue 2. 2012-07-30. PMID:22437740. |
2-arachidonoylglicerol (2-ag) is an endocannabinoid that mimics the pharmacological effects of Δ⁹ tetrahydrocannabinol, the psychoactive component of the plant cannabis sativa. |
2012-07-30 |
2023-08-12 |
Not clear |
| Ana Juknat, Maciej Pietr, Ewa Kozela, Neta Rimmerman, Rivka Levy, Giovanni Coppola, Daniel Geschwind, Zvi Voge. Differential transcriptional profiles mediated by exposure to the cannabinoids cannabidiol and Δ9-tetrahydrocannabinol in BV-2 microglial cells. British journal of pharmacology. vol 165. issue 8. 2012-07-27. PMID:21542829. |
differential transcriptional profiles mediated by exposure to the cannabinoids cannabidiol and Δ9-tetrahydrocannabinol in bv-2 microglial cells. |
2012-07-27 |
2023-08-12 |
Not clear |
| Ana Juknat, Maciej Pietr, Ewa Kozela, Neta Rimmerman, Rivka Levy, Giovanni Coppola, Daniel Geschwind, Zvi Voge. Differential transcriptional profiles mediated by exposure to the cannabinoids cannabidiol and Δ9-tetrahydrocannabinol in BV-2 microglial cells. British journal of pharmacology. vol 165. issue 8. 2012-07-27. PMID:21542829. |
we previously showed that the psychoactive cannabinoid Δ(9) -tetrahydrocannabinol (thc) and the non-psychoactive cannabidiol (cbd) differ in their anti-inflammatory signalling pathways. |
2012-07-27 |
2023-08-12 |
Not clear |
| E M Rock, D Bolognini, C L Limebeer, M G Cascio, S Anavi-Goffer, P J Fletcher, R Mechoulam, R G Pertwee, L A Parke. Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT(1A) somatodendritic autoreceptors in the dorsal raphe nucleus. British journal of pharmacology. vol 165. issue 8. 2012-07-27. PMID:21827451. |
to evaluate the hypothesis that activation of somatodendritic 5-ht(1a) autoreceptors in the dorsal raphe nucleus (drn) produces the anti-emetic/anti-nausea effects of cannabidiol (cbd), a primary non-psychoactive cannabinoid found in cannabis. |
2012-07-27 |
2023-08-12 |
Not clear |
| Alex Straiker, Jim Wager-Miller, Jacqueline Hutchens, Ken Macki. Differential signalling in human cannabinoid CB1 receptors and their splice variants in autaptic hippocampal neurones. British journal of pharmacology. vol 165. issue 8. 2012-07-27. PMID:22014238. |
cannabinoids such as Δ(9) - tetrahydrocannabinol, the major psychoactive component of marijuana and hashish, primarily act via cannabinoid cb(1) and cb(2) receptors to produce characteristic behavioural effects in humans. |
2012-07-27 |
2023-08-12 |
human |
| R E Vann, D M Walentiny, J J Burston, K M Tobey, T F Gamage, J L Wile. Enhancement of the behavioral effects of endogenous and exogenous cannabinoid agonists by phenylmethyl sulfonyl fluoride. Neuropharmacology. vol 62. issue 2. 2012-07-27. PMID:22051632. |
these findings may account for the varying affect in response to marijuana in humans or cannabinoids in animals while also suggesting that metabolic inhibitors of aea may potentiate marijuana's intoxicating effects in humans. |
2012-07-27 |
2023-08-12 |
mouse |
| Barbara Malinowska, Marta Baranowska-Kuczko, Eberhard Schlicke. Triphasic blood pressure responses to cannabinoids: do we understand the mechanism? British journal of pharmacology. vol 165. issue 7. 2012-07-23. PMID:22022923. |
the cannabinoids comprise three major classes of substances, including compounds derived from the cannabis plant (e.g. |
2012-07-23 |
2023-08-12 |
Not clear |
| Joshua A Lile, Thomas H Kelly, Lon R Hay. Separate and combined effects of the GABA reuptake inhibitor tiagabine and Δ9-THC in humans discriminating Δ9-THC. Drug and alcohol dependence. vol 122. issue 1-2. 2012-07-20. PMID:21975195. |
gabaergic drugs have overlapping effects with cannabis and Δ(9)-tetrahydrocannabinol (Δ(9)-thc) on certain behavioral measures, but those measures lack the specificity to draw conclusions regarding the involvement of gaba in cannabinoid effects. |
2012-07-20 |
2023-08-12 |
Not clear |
| Jatin G Vaidya, Robert I Block, Daniel S O'Leary, Laura B Ponto, Mohamed M Ghoneim, Antoine Bechar. Effects of chronic marijuana use on brain activity during monetary decision-making. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 3. 2012-07-19. PMID:21956445. |
marijuana (mj) acutely acts on cannabinoid receptors that are found in numerous brain regions, including those involved in reward processing and decision-making. |
2012-07-19 |
2023-08-12 |
human |
| A Salomone, E Gerace, F D'Urso, D Di Corcia, M Vincent. Simultaneous analysis of several synthetic cannabinoids, THC, CBD and CBN, in hair by ultra-high performance liquid chromatography tandem mass spectrometry. Method validation and application to real samples. Journal of mass spectrometry : JMS. vol 47. issue 5. 2012-07-17. PMID:22576873. |
the method was successfully applied to the analysis of 179 real samples collected from proven consumers of cannabis, among which 14 were found positive to at least one synthetic cannabinoid. |
2012-07-17 |
2023-08-12 |
Not clear |
| Alison Ribeiro, Viviane Ferraz-de-Paula, Milena L Pinheiro, Luana B Vitoretti, Domenica P Mariano-Souza, Wanderley M Quinteiro-Filho, Adriana T Akamine, Vinícius I Almeida, João Quevedo, Felipe Dal-Pizzol, Jaime E Hallak, Antônio W Zuardi, José A Crippa, João Palermo-Net. Cannabidiol, a non-psychotropic plant-derived cannabinoid, decreases inflammation in a murine model of acute lung injury: role for the adenosine A(2A) receptor. European journal of pharmacology. vol 678. issue 1-3. 2012-07-09. PMID:22265864. |
cannabidiol, a non-psychotropic plant-derived cannabinoid, decreases inflammation in a murine model of acute lung injury: role for the adenosine a(2a) receptor. |
2012-07-09 |
2023-08-12 |
Not clear |
| Alison Ribeiro, Viviane Ferraz-de-Paula, Milena L Pinheiro, Luana B Vitoretti, Domenica P Mariano-Souza, Wanderley M Quinteiro-Filho, Adriana T Akamine, Vinícius I Almeida, João Quevedo, Felipe Dal-Pizzol, Jaime E Hallak, Antônio W Zuardi, José A Crippa, João Palermo-Net. Cannabidiol, a non-psychotropic plant-derived cannabinoid, decreases inflammation in a murine model of acute lung injury: role for the adenosine A(2A) receptor. European journal of pharmacology. vol 678. issue 1-3. 2012-07-09. PMID:22265864. |
cannabidiol, a non-psychotropic cannabinoid component of marijuana (cannabis sativa), has potent immunosuppressive and anti-inflammatory properties. |
2012-07-09 |
2023-08-12 |
Not clear |
| Garry Milman, David M Schwope, David A Gorelick, Marilyn A Huesti. Cannabinoids and metabolites in expectorated oral fluid following controlled smoked cannabis. Clinica chimica acta; international journal of clinical chemistry. vol 413. issue 7-8. 2012-06-15. PMID:22285315. |
cannabinoids and metabolites in expectorated oral fluid following controlled smoked cannabis. |
2012-06-15 |
2023-08-12 |
Not clear |
| Rebecca Andrews, Sue Paterso. Production of identical retention times and mass spectra for {delta}9-tetrahydrocannabinol and cannabidiol following derivatization with trifluoracetic anhydride with 1,1,1,3,3,3-hexafluoroisopropanol*. Journal of analytical toxicology. vol 36. issue 1. 2012-06-11. PMID:22290754. |
during method development for the analysis of cannabinoids in biological samples using gc-ms in ei and nci mode, it was observed that when Δ(9)-tetrahydrocannabinol (thc) and cannabidiol (cbd) were derivatized with trifluoroacetic anhydride (tfaa), the resultant derivatives produced the same retention times and mass spectra. |
2012-06-11 |
2023-08-12 |
Not clear |