| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jenny L Wiley, Julie A Marusich, Billy R Martin, John W Huffma. 1-Pentyl-3-phenylacetylindoles and JWH-018 share in vivo cannabinoid profiles in mice. Drug and alcohol dependence. vol 123. issue 1-3. 2012-09-13. PMID:22127210. |
the indole-derived cannabinoids identified in these products were originally developed as research tools and are structurally distinct from cannabinoids in the cannabis plant. |
2012-09-13 |
2023-08-12 |
mouse |
| Andrew Zalesky, Nadia Solowij, Murat Yücel, Dan I Lubman, Michael Takagi, Ian H Harding, Valentina Lorenzetti, Ruopeng Wang, Karissa Searle, Christos Pantelis, Marc Sea. Effect of long-term cannabis use on axonal fibre connectivity. Brain : a journal of neurology. vol 135. issue Pt 7. 2012-09-13. PMID:22669080. |
cannabis use typically begins during adolescence and early adulthood, a period when cannabinoid receptors are still abundant in white matter pathways across the brain. |
2012-09-13 |
2023-08-12 |
Not clear |
| Anderson O Cox, Richard C Daw, Michele D Mason, Megan Grabenauer, Poonam G Pande, Kenneth H Davis, Jenny L Wiley, Peter R Stout, Brian F Thomas, John W Huffma. Use of SPME-HS-GC-MS for the analysis of herbal products containing synthetic cannabinoids. Journal of analytical toxicology. vol 36. issue 5. 2012-09-10. PMID:22582264. |
in contrast to the plant-derived cannabinoids in medical marijuana and other cannabinoid-based therapeutics, the commonly encountered synthetic cannabinoids in these mendaciously labeled products constitute a structurally diverse set of compounds of relatively unknown pharmacology and toxicology. |
2012-09-10 |
2023-08-12 |
Not clear |
| Delphine Psychoyos, K Yaragudri Vinod, Jin Cao, Shan Xie, Richard L Hyson, Bogdan Wlodarczyk, Weimin He, Thomas B Cooper, Basalingappa L Hungund, Richard H Finnel. Cannabinoid receptor 1 signaling in embryo neurodevelopment. Birth defects research. Part B, Developmental and reproductive toxicology. vol 95. issue 2. 2012-09-06. PMID:22311661. |
in utero exposure to tetrahydrocannabinol, the psychoactive component of marijuana, is associated with an increased risk for neurodevelopmental defects in the offspring by interfering with the functioning of the endocannabinoid (ecb) system. |
2012-09-06 |
2023-08-12 |
mouse |
| Dayong Lee, Garry Milman, David M Schwope, Allan J Barnes, David A Gorelick, Marilyn A Huesti. Cannabinoid stability in authentic oral fluid after controlled cannabis smoking. Clinical chemistry. vol 58. issue 7. 2012-09-06. PMID:22532594. |
cannabinoid stability in authentic oral fluid after controlled cannabis smoking. |
2012-09-06 |
2023-08-12 |
Not clear |
| Nina B L Urban, Diana Martine. Neurobiology of addiction: insight from neurochemical imaging. The Psychiatric clinics of North America. vol 35. issue 2. 2012-09-06. PMID:22640769. |
predominantly reduced striatal dopamine transmission appears to play an important role in psychostimulant, alcohol and heroin addiction, while addiction to cannabis may be mediated primarily by the endocannabinoid system. |
2012-09-06 |
2023-08-12 |
human |
| Roland J Lamarin. Marijuana: modern medical chimaera. Journal of drug education. vol 42. issue 1. 2012-08-31. PMID:22873011. |
benefits related to medical use of cannabinoids are examined and a number of potential risks associated with cannabis use, both medical and recreational, are considered. |
2012-08-31 |
2023-08-12 |
Not clear |
| Gladys Torres, Fabián Fiesta. [Effects of marijuana on cognition: a review form the neurobiological perspective]. Revista peruana de medicina experimental y salud publica. vol 29. issue 1. 2012-08-24. PMID:22510918. |
there is evidence suggesting that cannabinoids, marijuana's primary psychoactive substance, have a negative effect in short-term memory, working memory, and decision making. |
2012-08-24 |
2023-08-12 |
Not clear |
| Juan A Ramos, Fernando J Bianc. The role of cannabinoids in prostate cancer: Basic science perspective and potential clinical applications. Indian journal of urology : IJU : journal of the Urological Society of India. vol 28. issue 1. 2012-08-23. PMID:22557710. |
pubmed search utilizing the terms "cannabis," "cannabinoids," "prostate cancer," and "cancer pain management," giving preference to most recent publications was done. |
2012-08-23 |
2023-08-12 |
Not clear |
| Igor Grant, J Hampton Atkinson, Ben Gouaux, Barth Wilse. Medical marijuana: clearing away the smoke. The open neurology journal. vol 6. 2012-08-23. PMID:22629287. |
recent advances in understanding of the mode of action of tetrahydrocannabinol and related cannabinoid in-gredients of marijuana, plus the accumulating anecdotal reports on potential medical benefits have spurred increasing re-search into possible medicinal uses of cannabis. |
2012-08-23 |
2023-08-12 |
Not clear |
| Igor Grant, J Hampton Atkinson, Ben Gouaux, Barth Wilse. Medical marijuana: clearing away the smoke. The open neurology journal. vol 6. 2012-08-23. PMID:22629287. |
recent clinical trials with smoked and vaporized marijuana, as well as other botanical extracts indicate the likelihood that the cannabinoids can be useful in the management of neuropathic pain, spasticity due to multiple sclerosis, and possibly other indications. |
2012-08-23 |
2023-08-12 |
Not clear |
| F A Pamplona, R N Takahash. Psychopharmacology of the endocannabinoids: far beyond anandamide. Journal of psychopharmacology (Oxford, England). vol 26. issue 1. 2012-08-21. PMID:21652605. |
the study of endocannabinoid pharmacology has proceeded from the discovery of Δ9-tetrahydrocannabinol, the main psychoactive compound in cannabis sativa, to the identification of an endogenous endocannabinoid system that is essential for physiological modulation of neuronal functions. |
2012-08-21 |
2023-08-12 |
Not clear |
| M P Viveros, R Llorente, J Suarez, A Llorente-Berzal, M López-Gallardo, F Rodriguez de Fonsec. The endocannabinoid system in critical neurodevelopmental periods: sex differences and neuropsychiatric implications. Journal of psychopharmacology (Oxford, England). vol 26. issue 1. 2012-08-21. PMID:21669929. |
this review focuses on the endocannabinoid system as a crucial player during critical periods of brain development, and how its disturbance either by early life stressful events or cannabis consumption may lead to important neuropsychiatric signs and symptoms. |
2012-08-21 |
2023-08-12 |
Not clear |
| Tiziana Rubino, Erica Zamberletti, Daniela Parolar. Adolescent exposure to cannabis as a risk factor for psychiatric disorders. Journal of psychopharmacology (Oxford, England). vol 26. issue 1. 2012-08-21. PMID:21768160. |
cannabis is the most consumed drug among adolescent people and its heavy use may affect maturational refinement by disrupting the regulatory role of the endocannabinoid system. |
2012-08-21 |
2023-08-12 |
Not clear |
| Mateus Machado Bergamaschi, Regina Helena Costa Queiroz, Antonio Waldo Zuardi, José Alexandre S Cripp. Safety and side effects of cannabidiol, a Cannabis sativa constituent. Current drug safety. vol 6. issue 4. 2012-08-20. PMID:22129319. |
the keywords searched were "cannabinoids", "cannabidiol" and "side effects". |
2012-08-20 |
2023-08-12 |
Not clear |
| Lauren C Harte-Hargrove, Diana L Dow-Edward. Withdrawal from THC during adolescence: sex differences in locomotor activity and anxiety. Behavioural brain research. vol 231. issue 1. 2012-08-20. PMID:22421367. |
due to the localization of cannabinoid receptors within the limbic system and the established effects of cannabinoids on emotional states and anxiety levels of rats and humans, we studied the sex- and dose-related effects of Δ⁹-tetrahydrocannabinol (thc, the main psychoactive component in marijuana) on behavior and anxiety during spontaneous withdrawal. |
2012-08-20 |
2023-08-12 |
rat |
| C K Tung, T P Chiang, M La. Acute mental disturbance caused by synthetic cannabinoid: a potential emerging substance of abuse in Hong Kong. East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan. vol 22. issue 1. 2012-08-20. PMID:22447803. |
synthetic cannabinoids are hybrid herbal/chemical products which mimic the effects of cannabis. |
2012-08-20 |
2023-08-12 |
Not clear |
| Guillermo Velasco, Cristina Sánchez, Manuel Guzmá. Towards the use of cannabinoids as antitumour agents. Nature reviews. Cancer. vol 12. issue 6. 2012-08-20. PMID:22555283. |
various reports have shown that cannabinoids (the active components of marijuana and their derivatives) can reduce tumour growth and progression in animal models of cancer, in addition to their well-known palliative effects on some cancer-associated symptoms. |
2012-08-20 |
2023-08-12 |
Not clear |
| Peter T Nguyen, Cullen L Schmid, Kirsten M Raehal, Dana E Selley, Laura M Bohn, Laura J Sim-Selle. β-arrestin2 regulates cannabinoid CB1 receptor signaling and adaptation in a central nervous system region-dependent manner. Biological psychiatry. vol 71. issue 8. 2012-08-16. PMID:22264443. |
cannabinoid cb(1) receptors (cb(1)rs) mediate the effects of ▵(9)-tetrahydrocannabinol (thc), the psychoactive component in marijuana. |
2012-08-16 |
2023-08-12 |
Not clear |
| Dragan M Svrakic, Patrick J Lustman, Ashok Mallya, Taylor Andrea Lynn, Rhonda Finney, Neda M Svraki. Legalization, decriminalization & medicinal use of cannabis: a scientific and public health perspective. Missouri medicine. vol 109. issue 2. 2012-08-14. PMID:22675784. |
if there is any medical role for cannabinoid drugs, it lies with chemically defined compounds, not with unprocessed cannabis plant. |
2012-08-14 |
2023-08-12 |
Not clear |