| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M B Forrester, K Kleinschmidt, E Schwarz, A Youn. Synthetic cannabinoid and marijuana exposures reported to poison centers. Human & experimental toxicology. vol 31. issue 10. 2013-01-29. PMID:22859662. |
compared to marijuana, synthetic cannabinoid exposures were more likely to be used through inhalation, to involve adults, to be used at a residence, and to result in serious outcomes. |
2013-01-29 |
2023-08-12 |
Not clear |
| Satoshi Yamaori, Kyoko Koeda, Mika Kushihara, Yui Hada, Ikuo Yamamoto, Kazuhito Watanab. Comparison in the in vitro inhibitory effects of major phytocannabinoids and polycyclic aromatic hydrocarbons contained in marijuana smoke on cytochrome P450 2C9 activity. Drug metabolism and pharmacokinetics. vol 27. issue 3. 2013-01-11. PMID:22166891. |
these results indicated that the three major phytocannabinoids but not pahs contained in marijuana smoke potently inhibited cyp2c9 activity and that these cannabinoids can be characterized as direct inhibitors for cyp2c9. |
2013-01-11 |
2023-08-12 |
human |
| Patrick D Skosnik, Deepak C D'Souza, Adam B Steinmetz, Chad R Edwards, Jennifer M Vollmer, William P Hetrick, Brian F O'Donnel. The effect of chronic cannabinoids on broadband EEG neural oscillations in humans. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 10. 2013-01-09. PMID:22713908. |
in order to assess the effect of cannabinoids on broadband-frequency neural oscillations in humans, the current study examined the effect of chronic cannabis use on auditory steady-state responses (assrs) utilizing electroencephalography (eeg). |
2013-01-09 |
2023-08-12 |
Not clear |
| Shuso Takeda, Shunsuke Okajima, Hiroko Miyoshi, Kazutaka Yoshida, Yoshiko Okamoto, Tomoko Okada, Toshiaki Amamoto, Kazuhito Watanabe, Curtis J Omiecinski, Hironori Aramak. Cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration. Toxicology letters. vol 214. issue 3. 2013-01-08. PMID:22963825. |
cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of mda-mb-231 breast cancer cell migration. |
2013-01-08 |
2023-08-12 |
human |
| Sabine Steffens, Pál Pache. Targeting cannabinoid receptor CB(2) in cardiovascular disorders: promises and controversies. British journal of pharmacology. vol 167. issue 2. 2013-01-07. PMID:22612332. |
the discovery that Δ-9-tetrahydrocannabinol (Δ9-thc), the main active constituent of marijuana, inhibited atherosclerotic plaque progression via a cannabinoid 2 (cb(2) ) receptor-dependent anti-inflammatory mechanism, and that certain natural and synthetic cannabinoid ligands could modulate the myocardial or cerebral ischaemia-reperfusion-induced tissue damage, have stimulated impetus for a growing number of studies investigating the implication of cb(2) receptors in atherosclerosis, restenosis, stroke, myocardial infarction and heart failure. |
2013-01-07 |
2023-08-12 |
Not clear |
| Andrew J Kwilasz, S Stevens Negu. Dissociable effects of the cannabinoid receptor agonists Δ9-tetrahydrocannabinol and CP55940 on pain-stimulated versus pain-depressed behavior in rats. The Journal of pharmacology and experimental therapeutics. vol 343. issue 2. 2012-12-31. PMID:22892341. |
to extend the range of preclinical cannabinoid assessment, this study compared the effects of the marijuana constituent and low-efficacy cannabinoid agonist Δ9-tetrahydrocannabinol (thc) and the high-efficacy synthetic cannabinoid agonist 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol (cp55940) in assays of pain-stimulated and pain-depressed behavior. |
2012-12-31 |
2023-08-12 |
rat |
| Yehoshua Maor, Jinlong Yu, Paula M Kuzontkoski, Bruce J Dezube, Xuefeng Zhang, Jerome E Groopma. Cannabidiol inhibits growth and induces programmed cell death in kaposi sarcoma-associated herpesvirus-infected endothelium. Genes & cancer. vol 3. issue 7-8. 2012-12-25. PMID:23264851. |
cannabidiol (cbd), a plant-derived cannabinoid, exhibits promising antitumor effects without inducing psychoactive side effects. |
2012-12-25 |
2023-08-12 |
Not clear |
| Jake M Stout, Zakia Boubakir, Stephen J Ambrose, Randy W Purves, Jonathan E Pag. The hexanoyl-CoA precursor for cannabinoid biosynthesis is formed by an acyl-activating enzyme in Cannabis sativa trichomes. The Plant journal : for cell and molecular biology. vol 71. issue 3. 2012-12-14. PMID:22353623. |
the hexanoyl-coa precursor for cannabinoid biosynthesis is formed by an acyl-activating enzyme in cannabis sativa trichomes. |
2012-12-14 |
2023-08-12 |
Not clear |
| Cristóbal S Berry-Cabán, Paul E Kleinschmidt, Dinesh S Rao, Jamie Jenkin. Synthetic cannabinoid and cathinone use among US soldiers. U.S. Army Medical Department journal. 2012-12-13. PMID:23007932. |
a large and complex variety of synthetic cannabinoids, most often cannabicyclohexanol, jwh-018, jwh-073, or hu-210, are used in an attempt to avoid the laws that make cannabis illegal, making synthetic cannabis a designer drug. |
2012-12-13 |
2023-08-12 |
Not clear |
| F F Youssef, A J Irvin. From cannabis to the endocannabinoid system: refocussing attention on potential clinical benefits. The West Indian medical journal. vol 61. issue 3. 2012-12-11. PMID:23155985. |
from cannabis to the endocannabinoid system: refocussing attention on potential clinical benefits. |
2012-12-11 |
2023-08-12 |
human |
| F F Youssef, A J Irvin. From cannabis to the endocannabinoid system: refocussing attention on potential clinical benefits. The West Indian medical journal. vol 61. issue 3. 2012-12-11. PMID:23155985. |
during this time, the primary active ingredients in cannabis have been isolated, specific cannabinoid receptors have been discovered and at least five endogenous cannabinoid neurotransmitters (endocannabinoids) have been identified. |
2012-12-11 |
2023-08-12 |
human |
| Rudolf Moldzio, Thomas Pacher, Christopher Krewenka, Barbara Kranner, Johannes Novak, Johanna Catharina Duvigneau, Wolf-Dieter Rausc. Effects of cannabinoids Δ(9)-tetrahydrocannabinol, Δ(9)-tetrahydrocannabinolic acid and cannabidiol in MPP+ affected murine mesencephalic cultures. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 19. issue 8-9. 2012-12-04. PMID:22571976. |
effects of cannabinoids Δ(9)-tetrahydrocannabinol, Δ(9)-tetrahydrocannabinolic acid and cannabidiol in mpp+ affected murine mesencephalic cultures. |
2012-12-04 |
2023-08-12 |
mouse |
| Rudolf Moldzio, Thomas Pacher, Christopher Krewenka, Barbara Kranner, Johannes Novak, Johanna Catharina Duvigneau, Wolf-Dieter Rausc. Effects of cannabinoids Δ(9)-tetrahydrocannabinol, Δ(9)-tetrahydrocannabinolic acid and cannabidiol in MPP+ affected murine mesencephalic cultures. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 19. issue 8-9. 2012-12-04. PMID:22571976. |
cannabinoids derived from cannabis sativa demonstrate neuroprotective properties in various cellular and animal models. |
2012-12-04 |
2023-08-12 |
mouse |
| A Hazekamp, J T Fischedic. Cannabis - from cultivar to chemovar. Drug testing and analysis. vol 4. issue 7-8. 2012-12-03. PMID:22362625. |
the cannabinoids and terpenoids, present in high concentrations in cannabis flowers, are the main candidates. |
2012-12-03 |
2023-08-12 |
Not clear |
| Benjamin De Backer, Kevin Maebe, Alain G Verstraete, Corinne Charlie. Evolution of the content of THC and other major cannabinoids in drug-type cannabis cuttings and seedlings during growth of plants. Journal of forensic sciences. vol 57. issue 4. 2012-12-03. PMID:22390363. |
evolution of the content of thc and other major cannabinoids in drug-type cannabis cuttings and seedlings during growth of plants. |
2012-12-03 |
2023-08-12 |
Not clear |
| Benjamin De Backer, Kevin Maebe, Alain G Verstraete, Corinne Charlie. Evolution of the content of THC and other major cannabinoids in drug-type cannabis cuttings and seedlings during growth of plants. Journal of forensic sciences. vol 57. issue 4. 2012-12-03. PMID:22390363. |
the aim of our study was to evaluate when the chemotype of cannabis plantlets can be surely determined through analysis of eight major cannabinoids content during growth. |
2012-12-03 |
2023-08-12 |
Not clear |
| Brendan J Holland, Paul S Francis, Bingshan Li, Takuya Tsuzuki, Jacqui L Adcock, Neil W Barnett, Xavier A Conla. Chemiluminescence detection of cannabinoids and related compounds with acidic potassium permanganate. Drug testing and analysis. vol 4. issue 7-8. 2012-12-03. PMID:22461321. |
this is the first report of chemiluminescence from the reaction of cannabinoids with acidic potassium permanganate, which we have applied to the high performance liquid chromatography (hplc) determination of cannabidiol (cbd) in industrial-grade hemp. |
2012-12-03 |
2023-08-12 |
Not clear |
| Brendan J Holland, Paul S Francis, Bingshan Li, Takuya Tsuzuki, Jacqui L Adcock, Neil W Barnett, Xavier A Conla. Chemiluminescence detection of cannabinoids and related compounds with acidic potassium permanganate. Drug testing and analysis. vol 4. issue 7-8. 2012-12-03. PMID:22461321. |
this analytical approach has potential for the determination of other cannabinoids including Δ(9) -tetrahydrocannabinol in drug-grade cannabis. |
2012-12-03 |
2023-08-12 |
Not clear |
| Gareth Pryce, David Bake. Potential control of multiple sclerosis by cannabis and the endocannabinoid system. CNS & neurological disorders drug targets. vol 11. issue 5. 2012-11-19. PMID:22583441. |
potential control of multiple sclerosis by cannabis and the endocannabinoid system. |
2012-11-19 |
2023-08-12 |
Not clear |
| Gabriella Aviello, Barbara Romano, Francesca Borrelli, Raffaele Capasso, Laura Gallo, Fabiana Piscitelli, Vincenzo Di Marzo, Angelo A Izz. Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer. Journal of molecular medicine (Berlin, Germany). vol 90. issue 8. 2012-11-16. PMID:22231745. |
cannabidiol, a safe and non-psychotropic ingredient of cannabis sativa, exerts pharmacological actions (antioxidant and intestinal antinflammatory) and mechanisms (inhibition of endocannabinoid enzymatic degradation) potentially beneficial for colon carcinogenesis. |
2012-11-16 |
2023-08-12 |
mouse |