| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Flávia Karine Rigo, Liana Pasquetti, Carlos Ricardo Maneck Malfatti, Michele Rechia Fighera, Rafael Correa Coelho, Cristiane Zanardo Petri, Carlos Fernando Mell. Propionic acid induces convulsions and protein carbonylation in rats. Neuroscience letters. vol 408. issue 2. 2007-04-06. PMID:16997462. |
pa-induced seizures and increased protein carbonylation in the striatum were prevented by the injection of mk-801 (3 nmol/0.5 microl). |
2007-04-06 |
2023-08-12 |
rat |
| Beatriz Martínez-Villayandre, Miguel Angel Paniagua, Arsenio Fernández-López, Pedro Calv. Effect of delta-aminolevulinic acid and vitamin E treatments on the N-methyl-D-aspartate receptor at different ages in the striatum of rat brain. Brain research. vol 1114. issue 1. 2006-11-28. PMID:16956596. |
[3h]mk-801 binding in the striatum was significantly decreased at all ages in ala-treated rats with respect to their controls, and in contrast, was significantly increased at all ages when rats received the treatment with vitamin e. western blot assays were performed using antibodies against the nr2a subunit, a nmda receptor subunit widely distributed in the brain. |
2006-11-28 |
2023-08-12 |
rat |
| Raphaël Faucard, Vincent Armand, Anne Héron, Véronique Cochois, Jean-Charles Schwartz, Jean-Michel Arran. N-methyl-D-aspartate receptor antagonists enhance histamine neuron activity in rodent brain. Journal of neurochemistry. vol 98. issue 5. 2006-10-03. PMID:16923161. |
the enhancement of t-meha levels elicited by mk-801 (ed50 of approximately 0.1 mg/kg) was observed in the hypothalamus, cerebral cortex, striatum and hippocampus. |
2006-10-03 |
2023-08-12 |
mouse |
| B M Campbell, C W Kreipke, P D Walke. Failure of MK-801 to suppress D1 receptor-mediated induction of locomotor activity and striatal preprotachykinin mRNA expression in the dopamine-depleted rat. Neuroscience. vol 137. issue 2. 2006-05-03. PMID:16289829. |
similarly, direct infusion of (+/-)6-chloro-7, 8-dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepine hydrobromide (3.0 microg) into the intact striatum produced an increase in locomotor activity that was suppressed by mk-801 (1.0 microg) co-infusion. |
2006-05-03 |
2023-08-12 |
rat |
| David M Thomas, Donald M Kuh. MK-801 and dextromethorphan block microglial activation and protect against methamphetamine-induced neurotoxicity. Brain research. vol 1050. issue 1-2. 2005-09-22. PMID:15987631. |
in vivo, mk-801 and dextromethorphan reduce methamphetamine-induced activation of microglia in striatum and they protect dopamine nerve endings against drug-induced nerve terminal damage. |
2005-09-22 |
2023-08-12 |
mouse |
| T Uchida, J Lee, S Fujita, M Kiguchi, M Matsumoto, Y Oi, N Gionhaku, N Koshikaw. Effects of NMDA and MK-801 injected into the substantia nigra pars reticulata on jaw movements evoked by dopamine D1-/D2 receptor stimulation in the ventrolateral striatum: studies in freely moving rats. Methods and findings in experimental and clinical pharmacology. vol 27. issue 1. 2005-06-21. PMID:15834457. |
effects of nmda and mk-801 injected into the substantia nigra pars reticulata on jaw movements evoked by dopamine d1-/d2 receptor stimulation in the ventrolateral striatum: studies in freely moving rats. |
2005-06-21 |
2023-08-12 |
rat |
| T Uchida, J Lee, S Fujita, M Kiguchi, M Matsumoto, Y Oi, N Gionhaku, N Koshikaw. Effects of NMDA and MK-801 injected into the substantia nigra pars reticulata on jaw movements evoked by dopamine D1-/D2 receptor stimulation in the ventrolateral striatum: studies in freely moving rats. Methods and findings in experimental and clinical pharmacology. vol 27. issue 1. 2005-06-21. PMID:15834457. |
the effects of nmda and mk-801 injected into the substantia nigra pars reticulata on jaw movements evoked by dopamine d1/d2 receptor stimulation in the ventrolateral striatum were examined in freely moving rats, by using a magnet-sensing system combined with intracerebral drug microinjection technique. |
2005-06-21 |
2023-08-12 |
rat |
| Carolina Demarchi Munhoz, Elisa Mitiko Kawamoto, Larissa de Sá Lima, Lucilia Brochado Lepsch, Isaias Glezer, Tania Marcourakis, Cristoforo Scavon. Glutamate modulates sodium-potassium-ATPase through cyclic GMP and cyclic GMP-dependent protein kinase in rat striatum. Cell biochemistry and function. vol 23. issue 2. 2005-06-09. PMID:15624118. |
mk-801 was not synergistic to l-name (nos inhibitor), suggesting that glutamate stimulates the nmda-nos pathway to activate alpha2,3 na+k+-atpase in rat striatum. |
2005-06-09 |
2023-08-12 |
rat |
| Jean-Marc Taymans, Catarina Cruz, Anne Lesage, Josée E Leysen, Xavier Langloi. MK-801 alters RGS2 levels and adenylyl cyclase sensitivity in the rat striatum. Neuroreport. vol 16. issue 2. 2005-04-14. PMID:15671868. |
mk-801 alters rgs2 levels and adenylyl cyclase sensitivity in the rat striatum. |
2005-04-14 |
2023-08-12 |
rat |
| Taketo Isao, Kazufumi Akiyam. Effect of acute and chronic treatment with methamphetamine on mRNA expression of synaptotagmin IV and 25 KDa-synaptic-associated protein in the rat brain. Psychiatry and clinical neurosciences. vol 58. issue 4. 2004-12-07. PMID:15298655. |
pretreatment with 0.5 mg/kg dopamine d1 receptor antagonist (sch23390), but not 0.5 mg/kg n-methyl-d-aspartate (nmda) receptor antagonist (mk-801), significantly attenuated the increased sytiv mrna levels induced by acute meth administration in the striatum and the nucleus accumbens. |
2004-12-07 |
2023-08-12 |
rat |
| Taketo Isao, Kazufumi Akiyam. Effect of acute and chronic treatment with methamphetamine on mRNA expression of synaptotagmin IV and 25 KDa-synaptic-associated protein in the rat brain. Psychiatry and clinical neurosciences. vol 58. issue 4. 2004-12-07. PMID:15298655. |
pretreatment with 0.5 mg/kg sch23390, but not 0.5 mg/kg mk-801, significantly attenuated the increased snap25a mrna levels induced by acute meth administration in the striatum and the dentate gyrus of the hippocampus. |
2004-12-07 |
2023-08-12 |
rat |
| Shuichi Hara, Toshiji Mukai, Kunihiko Kurosaki, Fumi Kuriiwa, Takahiko End. Characterization of hydroxyl radical generation in the striatum of free-moving rats due to carbon monoxide poisoning, as determined by in vivo microdialysis. Brain research. vol 1016. issue 2. 2004-09-27. PMID:15246866. |
co poisoning significantly, though only slightly, increased extracellular glutamate in the striatum, and glutamate (glu) receptor antagonists, such as mk-801 (dizocilpine) and nbqx, failed to suppress the co-induced increase in 2,3-dhba. |
2004-09-27 |
2023-08-12 |
rat |
| Christian W Kreipke, Paul D Walke. NMDA receptor blockade attenuates locomotion elicited by intrastriatal dopamine D1-receptor stimulation. Synapse (New York, N.Y.). vol 53. issue 1. 2004-07-16. PMID:15150738. |
both systemic (0.1 mg/kg) and intrastriatal (1.0 microg) mk-801 pretreatments completely blocked locomotor and stereotypic activity elicited by 10 microg of skf 82958 directly infused into the striatum. |
2004-07-16 |
2023-08-12 |
Not clear |
| J Lee, N Rajakuma. Role of NR2B-containing N-methyl-D-aspartate receptors in haloperidol-induced c-Fos expression in the striatum and nucleus accumbens. Neuroscience. vol 122. issue 3. 2004-02-17. PMID:14622917. |
administration of haloperidol in rats leads to a robust induction of immediate-early genes including c-fos throughout the striatum, which is significantly attenuated by pretreatment with the non-competitive n-methyl-d-aspartate (nmda) receptor antagonist, mk-801. |
2004-02-17 |
2023-08-12 |
rat |
| J Lee, N Rajakuma. Role of NR2B-containing N-methyl-D-aspartate receptors in haloperidol-induced c-Fos expression in the striatum and nucleus accumbens. Neuroscience. vol 122. issue 3. 2004-02-17. PMID:14622917. |
in the medial part of the striatum, this attenuation was almost as marked as that seen following pretreatment with mk-801; however, in the lateral part mk-801 pretreatment led to a significantly greater reduction in the number of c-fos positive nuclei than did ro 25-6981 pretreatment. |
2004-02-17 |
2023-08-12 |
rat |
| Md Mahiuddin Ahmed, Masaru Yamamoto, Toshiyuki Chikuma, Md Khalilur Rahman, Takeshi Kat. Dose-dependent effect of MK-801 on the levels of neuropeptides processing enzymes in rat brain regions. Neuroscience research. vol 47. issue 2. 2003-12-11. PMID:14512142. |
in the present study, we investigated the dose dependent effect of (+) mk-801 on prolyl endopeptidase (pep), endopeptidase ec 24.15 (ep 24.15) and beta-d-glucuronidase activities as well as the protein levels of ep 24.15 and neuron specific enolase (nse) in the posterior cingulate/retrosplenial cortices (pc/rsc), hippocampus, frontal cortex and striatum of female rats 3 days after the treatment. |
2003-12-11 |
2023-08-12 |
rat |
| Tomas Olsson, Tadeusz Wieloch, Maj-Lis Smit. Brain damage in a mouse model of global cerebral ischemia. Effect of NMDA receptor blockade. Brain research. vol 982. issue 2. 2003-12-01. PMID:12915260. |
the non-competitive n-methyl-d-aspartate receptor blocker, mk-801, did not provide protection in the hippocampus, cortex, striatum or thalamus when administered 30 min prior to ischemia or 2 h after the end of ischemia, but selectively mitigated damage in the hippocampus, when administered immediately following ischemia. |
2003-12-01 |
2023-08-12 |
mouse |
| Vasily V Vorobyov, Nikolai V Schibaev, Micaela Morelli, Anna R Cart. EEG modifications in the cortex and striatum after dopaminergic priming in the 6-hydroxydopamine rat model of Parkinson's disease. Brain research. vol 972. issue 1-2. 2003-07-11. PMID:12711091. |
antagonism of nmda receptor with mk-801, a treatment known to block the development of priming, increased apomorphine inhibitory effect mainly in the striatum, producing the same degree of inhibition in the two structures. |
2003-07-11 |
2023-08-12 |
rat |
| Vasily V Vorobyov, Nikolai V Schibaev, Micaela Morelli, Anna R Cart. EEG modifications in the cortex and striatum after dopaminergic priming in the 6-hydroxydopamine rat model of Parkinson's disease. Brain research. vol 972. issue 1-2. 2003-07-11. PMID:12711091. |
the inhibitory effect of skf 38393 was enhanced in rats primed with mk-801 plus apomorphine, particularly in the striatum. |
2003-07-11 |
2023-08-12 |
rat |
| M H Teicher, E Krenzel, A P Thompson, S L Anderse. Dopamine receptor pruning during the peripubertal period is not attenuated by NMDA receptor antagonism in rat. Neuroscience letters. vol 339. issue 2. 2003-04-04. PMID:12614921. |
in order to test the hypothesis that the pruning of dopamine d(1) and d(2) receptors that occurs in the striatum after puberty (which occurs at approximately 40 days of age; p40), male and female rats were treated with saline vehicle or mk-801 (0.3 mg/kg) for 20 or 40 days and sacrificed immediately after the 20 day treatment (p60), 40 day treatment (p80), or 40 day treatment with 40 day recovery (p120). |
2003-04-04 |
2023-08-12 |
rat |