| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Y Moore, J P Car. Neurotransmitter histochemistry: comparison of fluorescence and immunohistochemical methods. Methods in enzymology. vol 103. 1984-04-26. PMID:6142402. |
the immunohistochemical technique relies upon the availability of antisera generated against the catecholamine-synthesizing enzymes tyrosine hydroxylase (th), dopamine beta-hydroxylase(dbh), and phenylethanolamine n-methyltransferase (pnmt). |
1984-04-26 |
2023-08-12 |
Not clear |
| T H Joh, E E Baetge, M E Ross, D J Rei. Biochemistry and molecular biology of catecholamine neurons: a single gene or gene family hypothesis. Clinical and experimental hypertension. Part A, Theory and practice. vol 6. issue 1-2. 1984-04-17. PMID:6141853. |
we postulate that the catecholamine synthesizing enzyme, tyrosine hydroxylase (th), dopamine b-hydroxylase (dbh) and phenylethanolamine n-methyltransferase (pnmt) are coded for by similar gene coding sequence(s). |
1984-04-17 |
2023-08-12 |
Not clear |
| T Höktelt, B J Everitt, K Fuxe, M Kalia, L Agnati, O Johansson, A Härfstrand, J M Lundberg, L Terenius, E Theodorsson-Norhei. Transmitter and peptide systems in areas involved in the control of blood pressure. Clinical and experimental hypertension. Part A, Theory and practice. vol 6. issue 1-2. 1984-04-17. PMID:6141854. |
the distribution of catecholamine neurons in the dorsal vagal complex is described on the basis of indirect immunofluorescence histochemistry using antisera to three enzymes in the catecholamine synthesis, tyrosine hydroxylase, dopamine-beta-hydroxylase and phenylethanolamine-n-methyltransferase, allowing differentiation between dopamine, noradrenaline and adrenaline cells. |
1984-04-17 |
2023-08-12 |
Not clear |
| R M Kream, B J Davis, T Kawano, F L Margolis, F Macride. Substance P and catecholaminergic expression in neurons of the hamster main olfactory bulb. The Journal of comparative neurology. vol 222. issue 1. 1984-04-17. PMID:6199381. |
a coordinated series of immunohistochemical and biochemical analyses have been conducted in the hamster to examine the dependence of substance p and tyrosine hydroxylase (th) expression by second-order olfactory neurons, and the level of dopamine in the main olfactory bulb (mob), on the integrity of carnosine- and olfactory marker protein (omp)-containing primary afferent neurons. |
1984-04-17 |
2023-08-12 |
Not clear |
| L F Agnati, K Fuxe, L Calza, F Benfenati, L Cavicchioli, G Toffano, M Goldstei. Gangliosides increase the survival of lesioned nigral dopamine neurons and favour the recovery of dopaminergic synaptic function in striatum of rats by collateral sprouting. Acta physiologica Scandinavica. vol 119. issue 4. 1984-03-12. PMID:6141701. |
the effects of chronic ganglioside treatment gm-1 (10 mg/kg, i.p., once daily for 56 days) have been evaluated on the degenerative and regenerative features of nigrostriatal dopamine (da) neurons following a partial lesion by tyrosine hydroxylase immunocytochemistry in combination with morphometrical analysis and by quantitative da receptor autoradiography. |
1984-03-12 |
2023-08-12 |
rat |
| P A Larsson, M Goldstein, A Dahlströ. A new methodological approach for studying axonal transport: cytofluorometric scanning of nerves. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 32. issue 1. 1984-02-14. PMID:6197439. |
this article presents data on the accumulation of noradrenaline, dopamine beta-hydroxylase, and tyrosine hydroxylase in crush-operated rat sciatic nerve. |
1984-02-14 |
2023-08-12 |
rat |
| G A Ricaurte, R W Fuller, K W Perry, L S Seiden, C R Schuste. Fluoxetine increases long-lasting neostriatal dopamine depletion after administration of d-methamphetamine and d-amphetamine. Neuropharmacology. vol 22. issue 10. 1984-01-27. PMID:6606137. |
repeated administration of large doses of d-methamphetamine produce long-lasting depletion of brain dopamine (da) and serotonin (5-ht), as well as persistent decreases in the activity of their respective biosynthetic enzymes, tyrosine hydroxylase (th) and tryptophan hydroxylase (tph). |
1984-01-27 |
2023-08-12 |
Not clear |
| P M Iuvone, A L Rauc. Alpha 2-adrenergic receptors influence tyrosine hydroxylase activity in retinal dopamine neurons. Life sciences. vol 33. issue 24. 1984-01-26. PMID:6139733. |
alpha 2-adrenergic receptors influence tyrosine hydroxylase activity in retinal dopamine neurons. |
1984-01-26 |
2023-08-12 |
rat |
| C W Coen, M C Coomb. Effects of manipulating catecholamines on the incidence of the preovulatory surge of of luteinizing hormone and ovulation in the rat: evidence for a necessary involvement of hypothalamic adrenaline in the normal or 'midnight' surge. Neuroscience. vol 10. issue 1. 1984-01-07. PMID:6358942. |
alpha-methyl-p-tyrosine, diethyldithiocarbamate and skf 64139 inhibit catecholamine synthesis at the level of tyrosine hydroxylase, dopamine beta-hydroxylase and phenylethanolamine n-methyltransferase, respectively. |
1984-01-07 |
2023-08-12 |
rat |
| F C Iturriza, M C Rubio, C L Gómez Dumm, L M Ziehe. Catecholamine metabolizing enzymes and synthesis of dopamine in normal and grafted pituitary partes distales. Neuroendocrinology. vol 37. issue 5. 1984-01-07. PMID:6646350. |
the presence of enzymatic activity (tyrosine hydroxylase, dopa-decarboxylase, dopamine-beta-hydroxylase, monoamine oxydase and catechol-o-methyl transferase), as well as dopamine (da) content and da synthesis from tyrosine and dopa, were investigated in intact rats partes distales and in grafts (both estrogenized and nonestrogenized). |
1984-01-07 |
2023-08-12 |
rat |
| A A Grace, B S Bunne. Intracellular and extracellular electrophysiology of nigral dopaminergic neurons--1. Identification and characterization. Neuroscience. vol 10. issue 2. 1983-12-20. PMID:6633863. |
one of three compounds was injected intracellularly into each cell to produce the heightened fluorescence: (1) l-dopa, to increase the intracellular dopamine content by precursor loading; (2) tetrahydrobiopterin, a cofactor for tyrosine hydroxylase, to increase intracellular dopamine concentration through activation of the rate-limiting enzyme for dopamine synthesis and (3) colchicine, to arrest intraneuronal transport and thus allow the build-up of dopamine synthesizing enzymes and dopamine in the soma. |
1983-12-20 |
2023-08-12 |
rat |
| G L Pierpont, G S Francis, E G DeMaster, T B Levine, R M Bolman, J N Coh. Elevated left ventricular myocardial dopamine in preterminal idiopathic dilated cardiomyopathy. The American journal of cardiology. vol 52. issue 8. 1983-12-17. PMID:6356860. |
conversion of tyrosine to dopa by tyrosine hydroxylase is replaced as the rate-limiting step by inability to hydroxylate dopamine to norepinephrine. |
1983-12-17 |
2023-08-12 |
Not clear |
| J P Swerts, A Le Van Thai, A Vigny, M J Webe. Regulation of enzymes responsible for neurotransmitter synthesis and degradation in cultured rat sympathetic neurons. I. Effects of muscle-conditioned medium. Developmental biology. vol 100. issue 1. 1983-11-23. PMID:6137428. |
the activities of tyrosine hydroxylase (toh), dopa decarboxylase, and dopamine beta-hydroxylase were all about twofold lower in homogenates from cm+ cultures. |
1983-11-23 |
2023-08-12 |
rat |
| H A Houwing, J C van Oene, A S Hor. 3,4-disubstituted phenyliminoimidazolidines as potential prodrugs of the purported dopamine agonist 3,4-dihydroxyphenylimino-2-imidazolidine (DPI). Pharmaceutisch weekblad. Scientific edition. vol 5. issue 4. 1983-11-23. PMID:6622213. |
their effects on both dopamine and noradrenaline utilization in the rat brain have been investigated using the tyrosine hydroxylase inhibitor alpha-methyl-p-tyrosine. |
1983-11-23 |
2023-08-12 |
rat |
| P M Iuvon. Short-term regulation of tyrosine hydroxylase in tonically-active and in tonically-inactive dopamine neurons: effects of haloperidol and protein phosphorylation. Life sciences. vol 33. issue 13. 1983-10-28. PMID:6136885. |
short-term regulation of tyrosine hydroxylase in tonically-active and in tonically-inactive dopamine neurons: effects of haloperidol and protein phosphorylation. |
1983-10-28 |
2023-08-12 |
rat |
| P M Iuvon. Short-term regulation of tyrosine hydroxylase in tonically-active and in tonically-inactive dopamine neurons: effects of haloperidol and protein phosphorylation. Life sciences. vol 33. issue 13. 1983-10-28. PMID:6136885. |
dopamine (da)-containing neurons of retina were employed as an experimental model for studying the short-term regulation of tyrosine hydroxylase (th) in tonically-active and tonically-inactive neurons. |
1983-10-28 |
2023-08-12 |
rat |
| S K Rastogi, R B Rastogi, R L Singhal, Y D Lapierr. Behavioural and biochemical alterations following haloperidol treatment and withdrawal: the animal model of tardive dyskinesia reexamined. Progress in neuro-psychopharmacology & biological psychiatry. vol 7. issue 2-3. 1983-10-28. PMID:6137027. |
chronic haloperidol treatment significantly decreased dopamine synthesis and release as evidenced by low activity of tyrosine hydroxylase and low level of homovanillic acid in striatum. |
1983-10-28 |
2023-08-12 |
rat |
| T Ieiri, N Kase, Y Hashigami, H Kobori, T Nakamura, S Shimod. [Effects of gamma-oryzanol on the hypothalamo-pituitary axis in the rat]. Nihon Naibunpi Gakkai zasshi. vol 58. issue 10. 1983-10-21. PMID:7185574. |
gamma-oz increased medial basal hypothalamic (mbh) dopamine (da) content, and the da content was decreased by a treatment of alpha-methyl-p-tyrosine (alpha mpt), a tyrosine hydroxylase inhibitor, indicating increased synthesis and release of da in mbh by gamma-oz. |
1983-10-21 |
2023-08-12 |
rat |
| M A Thompson, D E Woolley, D W Gietzen, S Conwa. Catecholamine synthesis inhibitors acutely modulate [3H]estradiol binding by specific brain areas and pituitary in ovariectomized rats. Endocrinology. vol 113. issue 3. 1983-09-23. PMID:6135604. |
administration of the tyrosine hydroxylase inhibitor alpha-methyl-p-tyrosine (alpha mpt) 2 h before [3h]e2, to reduce levels of dopamine (da), norepinephrine (ne), and epinephrine (ep), decreased total and specific [3h]e2 binding by 36-56% in the nuclear fraction of the anterior pituitary, basal hypothalamus, and anterior hypothalamus. |
1983-09-23 |
2023-08-12 |
rat |
| M S Levine, C D Hull, R S Fisher, N A Buchwald, A Helle. Effects of neonatal destruction of the medial forebrain bundle in the cat: long-term neurochemical, locomotor, and regulatory deficits. Experimental neurology. vol 81. issue 2. 1983-09-09. PMID:6135623. |
caudate dopamine and tyrosine hydroxylase were measured after the animals were killed. |
1983-09-09 |
2023-08-12 |
cat |