| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Verney, M Baulac, B Berger, C Alvarez, A Vigny, K B Hell. Morphological evidence for a dopaminergic terminal field in the hippocampal formation of young and adult rat. Neuroscience. vol 14. issue 4. 1985-07-23. PMID:2860616. |
we have visualized the dopaminergic innervation of the hippocampal formation of the rat using two morphological methods: (1) tyrosine hydroxylase immunocytochemistry on noradrenaline-depleted animals and (2) fluorescence histochemistry after the uptake and storage of dopamine on hippocampal slices in vitro. |
1985-07-23 |
2023-08-11 |
rat |
| C J Schmidt, J W Gib. Role of the dopamine uptake carrier in the neurochemical response to methamphetamine: effects of amfonelic acid. European journal of pharmacology. vol 109. issue 1. 1985-07-18. PMID:2581794. |
coadministration of the dopamine uptake inhibitor, amfonelic acid, selectively prevented the methamphetamine-induced decrease in tyrosine hydroxylase activity while not altering the depression of tryptophan hydroxylase activity. |
1985-07-18 |
2023-08-11 |
Not clear |
| G A Foster, T Hökfelt, J T Coyle, M Goldstei. Immunohistochemical evidence for phenylethanolamine-N-methyltransferase-positive/tyrosine hydroxylase-negative neurones in the retina and the posterior hypothalamus of the rat. Brain research. vol 330. issue 1. 1985-06-18. PMID:2859084. |
these neurons did not seem to contain tyrosine hydroxylase (th)-like or dopamine-beta-hydroxylase (dbh)-like immunoreactivity and were much smaller and more numerous than the previously described th-positive dopamine neurons. |
1985-06-18 |
2023-08-11 |
rat |
| R B Simerly, L W Swanson, R A Gorsk. The distribution of monoaminergic cells and fibers in a periventricular preoptic nucleus involved in the control of gonadotropin release: immunohistochemical evidence for a dopaminergic sexual dimorphism. Brain research. vol 330. issue 1. 1985-06-18. PMID:2859086. |
sections through the avpv of both colchicine and non-colchicine-treated adult male and female sprague-dawley rats were processed for immunohistofluorescence with antisera directed against tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), or serotonin (5-ht), and were subsequently counterstained with the fluorescent nissl stain ethidium bromide. |
1985-06-18 |
2023-08-11 |
rat |
| D R Compton, K M Johnso. Striatal synaptosomal dopamine synthesis: evidence against direct regulation by an autoreceptor mechanism. European journal of pharmacology. vol 110. issue 2. 1985-06-18. PMID:2859213. |
regulation of the rate-limiting step in dopamine (da) synthesis was estimated in striatal synaptosomes by measuring the rate of hydroxylation of l-4-[3h]phenylalanine, a substrate of tyrosine hydroxylase (th). |
1985-06-18 |
2023-08-11 |
Not clear |
| J P Gagner, S Gauthier, T L Sourke. Differential effects of transection of the spinal cord and splanchnic nerve on adrenal tyrosine hydroxylase and catecholamines. Neuroscience. vol 14. issue 3. 1985-06-14. PMID:2859554. |
this treatment led after three days to a progressive reduction of tyrosine hydroxylase activity and dopamine content (as compared to unoperated controls) until at least the 10th day. |
1985-06-14 |
2023-08-11 |
rat |
| J P Gagner, S Gauthier, T L Sourke. Differential effects of transection of the spinal cord and splanchnic nerve on adrenal tyrosine hydroxylase and catecholamines. Neuroscience. vol 14. issue 3. 1985-06-14. PMID:2859554. |
the decline of adrenal tyrosine hydroxylase and dopamine after spinal section may result from a decrease of modulatory impulses to the adrenal from decentralized sympathoadrenal preganglionic neurons in the isolated cord, following the loss of a descending facilitation of these neurons and/or the release of a segmental interneuronal inhibition of these neurons from a descending inhibitory influence. |
1985-06-14 |
2023-08-11 |
rat |
| J P Gagner, S Gauthier, T L Sourke. Differential effects of transection of the spinal cord and splanchnic nerve on adrenal tyrosine hydroxylase and catecholamines. Neuroscience. vol 14. issue 3. 1985-06-14. PMID:2859554. |
such descending pathways may decussate partially below the low cervical level because rats with hemisection of the cord at c6-c7 exhibited no decline of adrenal tyrosine hydroxylase or of dopamine measured on either side seven days postoperatively. |
1985-06-14 |
2023-08-11 |
rat |
| M Ekker, T L Sourke. Effects of alpha-difluoromethylornithine on polyamine biosynthesis and tyrosine hydroxylase induction in the adrenal gland of the rat subjected to stress or apomorphine. Biochemical pharmacology. vol 34. issue 8. 1985-06-06. PMID:2859859. |
ornithine decarboxylase (odc) and tyrosine hydroxylase (th), the first enzymes in the polyamine and catecholamine biosynthetic pathways, respectively, are induced in the adrenal gland of the rat through the application of stressors or dopamine agonists. |
1985-06-06 |
2023-08-11 |
rat |
| M Bräutigam, B Kittner, H Herke. Evaluation of neurotropic drug actions on tyrosine hydroxylase activity and dopamine metabolism in clonal cell lines. Arzneimittel-Forschung. vol 35. issue 1A. 1985-05-23. PMID:2859029. |
evaluation of neurotropic drug actions on tyrosine hydroxylase activity and dopamine metabolism in clonal cell lines. |
1985-05-23 |
2023-08-11 |
Not clear |
| M Bräutigam, B Kittner, H Herke. Evaluation of neurotropic drug actions on tyrosine hydroxylase activity and dopamine metabolism in clonal cell lines. Arzneimittel-Forschung. vol 35. issue 1A. 1985-05-23. PMID:2859029. |
two clonal cell lines (the pheochromocytoma clone pc-12 and the neuroblastoma clone n1e-115) were used to compare direct and indirect drug effects on tyrosine hydroxylase and dopamine turnover. |
1985-05-23 |
2023-08-11 |
Not clear |
| M Bräutigam, B Kittner, H Herke. Evaluation of neurotropic drug actions on tyrosine hydroxylase activity and dopamine metabolism in clonal cell lines. Arzneimittel-Forschung. vol 35. issue 1A. 1985-05-23. PMID:2859029. |
the regulating enzyme for dopa synthesis, tyrosine hydroxylase, can be inhibited by certain drugs either directly or indirectly by increasing dopamine concentrations in the cytoplasm after release from its vesicular stores. |
1985-05-23 |
2023-08-11 |
Not clear |
| M Bräutigam, B Kittner, H Herke. Evaluation of neurotropic drug actions on tyrosine hydroxylase activity and dopamine metabolism in clonal cell lines. Arzneimittel-Forschung. vol 35. issue 1A. 1985-05-23. PMID:2859029. |
after total depletion of dopamine by nigericin at high concentrations or long-term incubation with 3-hydroxybenzyl-hydrazine (nsd 1015), dopa production increased in the pc-12 cells indicating a usually occurring regulation of tyrosine hydroxylase by cytoplasmic dopamine. |
1985-05-23 |
2023-08-11 |
Not clear |
| T H Jo. Genomic and phenotypic expression of autonomic neurons. Advances in experimental medicine and biology. vol 181. 1985-05-08. PMID:6152375. |
we found that catecholamine biosynthetic enzymes, tyrosine hydroxylase, dopamine b-hydroxylase and phenylethanolamine n-methyl-transferase share similar protein domains in their primary structures, and therefore are coded for by a single gene or a family of genes. |
1985-05-08 |
2023-08-12 |
Not clear |
| S Spencer, C B Saper, T Joh, D J Reis, M Goldstein, J D Raes. Distribution of catecholamine-containing neurons in the normal human hypothalamus. Brain research. vol 328. issue 1. 1985-04-19. PMID:2857591. |
our data indicate that the hypothalamic neuroendocrine dopamine neurons in the human brain are distributed in a pattern similar to that in other primate species, and that both postmortem tyrosine hydroxylase and melanin staining provide an incomplete but representative sampling of the periventricular-arcuate cell group. |
1985-04-19 |
2023-08-11 |
human |
| A N van den Pol, R S Herbst, J F Powel. Tyrosine hydroxylase-immunoreactive neurons of the hypothalamus: a light and electron microscopic study. Neuroscience. vol 13. issue 4. 1985-04-09. PMID:6152034. |
absorption of the antiserum with purified tyrosine hydroxylase abolished immunocytochemical staining, while addition of bovine dopamine beta-hydroxylase had no effect on immunostaining. |
1985-04-09 |
2023-08-12 |
rat |
| J M Feldma. Increased dopamine production in patients with carcinoid tumors. Metabolism: clinical and experimental. vol 34. issue 3. 1985-04-05. PMID:3974452. |
although both carcinoid tumors and pheochromocytomas arise from neural crest origin, they are thought to each secrete distinctive monoamines; carcinoid tumors, which contain tryptophan hydroxylase, secrete serotonin, and pheochromocytomas, which contain tyrosine hydroxylase, may secrete dopamine (da), norepinephrine (ne), or epinephrine (e). |
1985-04-05 |
2023-08-11 |
Not clear |
| L R Halpern-Sebold, H Margolis-Kazan, M P Schreibman, T H Jo. Immunoreactive tyrosine hydroxylase in the brain and pituitary gland of the platyfish. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). vol 178. issue 3. 1985-04-03. PMID:2858104. |
immunoreactive tyrosine hydroxylase (ir-th), the rate-limiting enzyme for the synthesis of dopamine and other catecholamines, was localized in the brain and pituitary gland of sexually mature platyfish (xiphophorus maculatus). |
1985-04-03 |
2023-08-11 |
Not clear |
| G M Jonakait, K A Markey, M Goldstein, C F Dreyfus, I B Blac. Selective expression of high-affinity uptake of catecholamines by transiently catecholaminergic cells of the rat embryo: studies in vivo and in vitro. Developmental biology. vol 108. issue 1. 1985-03-29. PMID:2857667. |
by combining the techniques of radioautography following accumulation of [3h]norepinephrine (3h-ne) and [3h]dopamine (3h-da) with immunohistochemical detection of tyrosine hydroxylase (t-oh), it has been possible to demonstrate simultaneously ca accumulation by t-oh-positive gut cells. |
1985-03-29 |
2023-08-11 |
rat |
| J Atkinson, M Sonnay, N Boilla. Changes in central monoaminergic function during chronic treatment with clonidine in the spontaneously hypertensive rat. European journal of pharmacology. vol 106. issue 3. 1985-03-05. PMID:6519179. |
no other changes in central monoaminergic function in either cortex or hindbrain were detected at the level of the enzymes (tyrosine hydroxylase) of the neurotransmitters (noradrenaline, dopamine) or of the adrenoceptors [( 3h]clonidine binding). |
1985-03-05 |
2023-08-12 |
rat |